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1ATZ
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BU of 1atz by Molmil
HUMAN VON WILLEBRAND FACTOR A3 DOMAIN
Descriptor: VON WILLEBRAND FACTOR
Authors:Huizinga, E.G, Gros, P.
Deposit date:1997-08-15
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the A3 domain of human von Willebrand factor: implications for collagen binding.
Structure, 5, 1997
2MAD
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BU of 2mad by Molmil
THE ACTIVE SITE STRUCTURE OF METHYLAMINE DEHYDROGENASE: HYDRAZINES IDENTIFY C6 AS THE REACTIVE SITE OF THE TRYPTOPHAN DERIVED QUINONE COFACTOR
Descriptor: METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT)
Authors:Huizinga, E.G, Vellieux, F.M.D, Hol, W.G.J.
Deposit date:1992-05-20
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor.
Biochemistry, 31, 1992
1MAF
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BU of 1maf by Molmil
The Active Site Structure of Methylamine Dehydrogenase: Hydrazines Identify C6 as the Reactive Site of the Tryptophan Derived Quinone Cofactor
Descriptor: METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT), NITROGEN MOLECULE
Authors:Huizinga, E.G, Vellieux, F.M.D, Hol, W.G.J.
Deposit date:1992-05-20
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor.
Biochemistry, 31, 1992
1MAE
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BU of 1mae by Molmil
The Active Site Structure of Methylamine Dehydrogenase: Hydrazines Identify C6 as the Reactive Site of the Tryptophan Derived Quinone Cofactor
Descriptor: METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT), METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT), NITROGEN MOLECULE
Authors:Huizinga, E.G, Vellieux, F.M.D, Hol, W.G.J.
Deposit date:1992-05-20
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor.
Biochemistry, 31, 1992
1I8N
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BU of 1i8n by Molmil
CRYSTAL STRUCTURE OF LEECH ANTI-PLATELET PROTEIN
Descriptor: ANTI-PLATELET PROTEIN, PROPIONAMIDE
Authors:Huizinga, E.G, Schouten, A, Connolly, T.M, Kroon, J, Sixma, J.J, Gros, P.
Deposit date:2001-03-15
Release date:2001-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of leech anti-platelet protein, an inhibitor of haemostasis.
Acta Crystallogr.,Sect.D, 57, 2001
1M10
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BU of 1m10 by Molmil
Crystal structure of the complex of Glycoprotein Ib alpha and the von Willebrand Factor A1 Domain
Descriptor: Glycoprotein Ib alpha, von Willebrand Factor
Authors:Huizinga, E.G, Tsuji, S, Romijn, R.A.P, Schiphorst, M.E, de Groot, P.G, Sixma, J.J, Gros, P.
Deposit date:2002-06-16
Release date:2002-08-28
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.
Science, 297, 2002
1M0Z
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BU of 1m0z by Molmil
Crystal Structure of the von Willebrand Factor Binding Domain of Glycoprotein Ib alpha
Descriptor: Glycoprotein Ib alpha
Authors:Huizinga, E.G, Tsuji, S, Romijn, R.A.P, Schiphorst, M.E, de Groot, P.G, Sixma, J.J, Gros, P.
Deposit date:2002-06-16
Release date:2002-08-28
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain.
Science, 297, 2002
6QFY
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BU of 6qfy by Molmil
CRYSTAL STRUCTURE OF PORCINE HEMAGGLUTINATING ENCEPHALOMYELITIS VIRUS SPIKE PROTEIN LECTIN DOMAIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Huizinga, E.G, Bakkers, M, Lang, Y.
Deposit date:2019-01-10
Release date:2019-02-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
1FE8
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BU of 1fe8 by Molmil
CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR A3 DOMAIN IN COMPLEX WITH A FAB FRAGMENT OF IGG RU5 THAT INHIBITS COLLAGEN BINDING
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, IMMUNOGLOBULIN IGG RU5, ...
Authors:Bouma, B, Huizinga, E.G, Schiphorst, M.E, Sixma, J.J, Kroon, J, Gros, P.
Deposit date:2000-07-21
Release date:2001-04-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Identification of the collagen-binding site of the von Willebrand factor A3-domain.
J.Biol.Chem., 276, 2001
5N11
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BU of 5n11 by Molmil
Crystal structure of Human beta1-coronavirus OC43 NL/A/2005 Hemagglutinin-Esterase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ...
Authors:Bakkers, M.J.G, Feitsma, L.J, de Groot, R.J, Huizinga, E.G.
Deposit date:2017-02-04
Release date:2017-03-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Betacoronavirus Adaptation to Humans Involved Progressive Loss of Hemagglutinin-Esterase Lectin Activity.
Cell Host Microbe, 21, 2017
4ZXN
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BU of 4zxn by Molmil
Crystal structure of rat coronavirus strain New-Jersey Hemagglutinin-Esterase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HE protein, SODIUM ION, ...
Authors:Bakkers, M.J.G, Feitsma, L.J, Huizinga, E.G, de Groot, R.J.
Deposit date:2015-05-20
Release date:2016-05-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of murine coronavirus hemagglutinin-esterases reveal structural basis for esterase substrate specificity
To Be Published
5AJ2
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BU of 5aj2 by Molmil
Cryo electron tomography of the Naip5-Nlrc4 inflammasome
Descriptor: NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4
Authors:Diebolder, C.A, Halff, E.F, Koster, A.J, Huizinga, E.G, Koning, R.I.
Deposit date:2015-02-20
Release date:2015-11-11
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (40 Å)
Cite:Cryoelectron Tomography of the Naip5/Nlrc4 Inflammasome: Implications for Nlr Activation.
Structure, 23, 2015
5JIF
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BU of 5jif by Molmil
Crystal structure of mouse hepatitis virus strain DVIM Hemagglutinin-Esterase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Zeng, Q.H, Bakkers, M.J.G, Feitsma, L.J, de Groot, R.J, Huizinga, E.G.
Deposit date:2016-04-22
Release date:2016-05-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Coronavirus receptor switch explained from the stereochemistry of protein-carbohydrate interactions and a single mutation.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JIL
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BU of 5jil by Molmil
Crystal structure of rat coronavirus strain New-Jersey Hemagglutinin-Esterase in complex with 4N-acetyl sialic acid
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-esterase, ...
Authors:Bakkers, M.J.G, Feitsma, L.J, de Groot, R.J, Huizinga, E.G.
Deposit date:2016-04-22
Release date:2016-05-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Coronavirus receptor switch explained from the stereochemistry of protein-carbohydrate interactions and a single mutation.
Proc.Natl.Acad.Sci.USA, 113, 2016
2I6S
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BU of 2i6s by Molmil
Complement component C2a
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C2a fragment, ...
Authors:Milder, F.J, Raaijmakers, H.C.A, Vandeputte, D.A.A, Schouten, A, Huizinga, E.G, Romijn, R.A, Hemrika, W, Roos, A, Daha, M.R, Gros, P.
Deposit date:2006-08-29
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of complement component c2a: implications for convertase formation and substrate binding.
Structure, 14, 2006
2I6Q
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BU of 2i6q by Molmil
Complement component C2a
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C2a fragment, ...
Authors:Milder, F.J, Raaijmakers, H.C.A, Vandeputte, D.A.A, Schouten, A, Huizinga, E.G, Romijn, R.A, Hemrika, W, Roos, A, Daha, M.R, Gros, P.
Deposit date:2006-08-29
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of complement component c2a: implications for convertase formation and substrate binding.
Structure, 14, 2006
2ADF
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BU of 2adf by Molmil
Crystal Structure and Paratope Determination of 82D6A3, an Antithrombotic Antibody Directed Against the von Willebrand factor A3-Domain
Descriptor: 82D6A3 IgG, ACETIC ACID, GLYCEROL, ...
Authors:Staelens, S, Hadders, M.A, Vauterin, S, Platteau, C, Vanhoorelbeke, K, Huizinga, E.G, Deckmyn, H.
Deposit date:2005-07-20
Release date:2005-12-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Paratope determination of the antithrombotic antibody 82D6A3 based on the crystal structure of its complex with the von Willebrand factor A3-domain
J.Biol.Chem., 281, 2006
6GRQ
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BU of 6grq by Molmil
Paired immunoglobulin-like receptor B (PirB) or Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3) full extracellular domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Paired immunoglobulin-like receptor B
Authors:Vlieg, H.C, Huizinga, E.G, Janssen, B.J.C.
Deposit date:2018-06-12
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure and flexibility of the extracellular region of the PirB receptor.
J.Biol.Chem., 294, 2019
6GRT
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BU of 6grt by Molmil
Paired immunoglobulin-like receptor B (PirB) or Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3) full extracellular domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Paired immunoglobulin-like receptor B, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Vlieg, H.C, Huizinga, E.G, Janssen, B.J.C.
Deposit date:2018-06-12
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (4.504 Å)
Cite:Structure and flexibility of the extracellular region of the PirB receptor.
J.Biol.Chem., 294, 2019
6GRS
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BU of 6grs by Molmil
Paired immunoglobulin-like receptor B (PirB) or Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3) full extracellular domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Paired immunoglobulin-like receptor B
Authors:Vlieg, H.C, Huizinga, E.G, Janssen, B.J.C.
Deposit date:2018-06-12
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure and flexibility of the extracellular region of the PirB receptor.
J.Biol.Chem., 294, 2019
5D3I
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BU of 5d3i by Molmil
Crystal structure of the SSL3-TLR2 complex
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Feitsma, L.J, Huizinga, E.G.
Deposit date:2015-08-06
Release date:2015-08-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3).
Proc.Natl.Acad.Sci.USA, 112, 2015
5D3D
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BU of 5d3d by Molmil
Crystal structure of Staphylococcal Superantigen-Like protein 3
Descriptor: CHLORIDE ION, GLYCEROL, SODIUM ION, ...
Authors:Feitsma, L.J, Huizinga, E.G.
Deposit date:2015-08-06
Release date:2015-08-19
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3).
Proc.Natl.Acad.Sci.USA, 112, 2015
2OK5
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BU of 2ok5 by Molmil
Human Complement factor B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement factor B, ...
Authors:Milder, F.J, Gomes, L, Schouten, A, Janssen, B.J.C, Huizinga, E.G, Romijn, R.A, Hemrika, W, Roos, A, Daha, M.R, Gros, P.
Deposit date:2007-01-16
Release date:2007-02-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Factor B structure provides insights into activation of the central protease of the complement system.
Nat.Struct.Mol.Biol., 14, 2007
3I1K
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BU of 3i1k by Molmil
Structure of porcine torovirus Hemagglutinin-Esterase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, Hemagglutinin-esterase protein
Authors:Zeng, Q.H, Huizinga, E.G.
Deposit date:2009-06-26
Release date:2009-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for ligand and substrate recognition by torovirus hemagglutinin esterases
Proc.Natl.Acad.Sci.USA, 106, 2009
3I27
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BU of 3i27 by Molmil
Structure of bovine torovirus Hemagglutinin-Esterase in complex with receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-esterase, ...
Authors:Zeng, Q.H, Huizinga, E.G.
Deposit date:2009-06-29
Release date:2009-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for ligand and substrate recognition by torovirus hemagglutinin esterases
Proc.Natl.Acad.Sci.USA, 106, 2009

 

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