Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
5U96
DownloadVisualize
BU of 5u96 by Molmil
Crystal structure of the coiled-coil domain from Listeria Innocua (Tetragonal Form)
Descriptor: Putative integrase
Authors:Gupta, K, Van Duyne, G.D, Sharp, R, Yuan, J.B.
Deposit date:2016-12-15
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Coiled-coil interactions mediate serine integrase directionality.
Nucleic Acids Res., 45, 2017
5UAE
DownloadVisualize
BU of 5uae by Molmil
Crystal structure of the coiled-coil domain from Listeria Innocua Phage Integrase (Trigonal Form)
Descriptor: CITRATE ANION, Putative integrase
Authors:Gupta, K, Sharp, R, Yuan, J.B, Van Duyne, G.D.
Deposit date:2016-12-19
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Coiled-coil interactions mediate serine integrase directionality.
Nucleic Acids Res., 45, 2017
5UDO
DownloadVisualize
BU of 5udo by Molmil
Crystal structure of the coiled-coil domain from Listeria Innocua Phage Integrase (Tetragonal Form II)
Descriptor: A118 serine integrase
Authors:Gupta, K, Yuan, J.B, Sharp, R, Van Duyne, G.D.
Deposit date:2016-12-28
Release date:2017-06-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.541 Å)
Cite:Coiled-coil interactions mediate serine integrase directionality.
Nucleic Acids Res., 45, 2017
4RG5
DownloadVisualize
BU of 4rg5 by Molmil
Crystal Structure of S. Pombe SMN YG-Dimer
Descriptor: MALONATE ION, Maltose-binding periplasmic protein, Survival Motor Neuron protein chimera, ...
Authors:Gupta, K, Martin, R.S, Sarachan, K.L, Sharp, B, Van Duyne, G.D.
Deposit date:2014-09-29
Release date:2015-07-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Oligomeric Properties of Survival Motor NeuronGemin2 Complexes.
J.Biol.Chem., 290, 2015
5HOT
DownloadVisualize
BU of 5hot by Molmil
Structural Basis for Inhibitor-Induced Aggregation of HIV-1 Integrase
Descriptor: (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinolin-3-yl]ethanoic acid, Integrase
Authors:Gupta, K, Turkki, V, Sherrill-Mix, S, Hwang, Y, Eilers, G, Taylor, L, McDanal, C, Wang, P, Temelkoff, D, Nolte, R, Velthuisen, E, Jeffrey, J, Van Duyne, G.D, Bushman, F.D.
Deposit date:2016-01-19
Release date:2016-12-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase.
PLoS Biol., 14, 2016
4OJR
DownloadVisualize
BU of 4ojr by Molmil
Crystal Structure of the HIV-1 Integrase catalytic domain with GSK1264
Descriptor: (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinolin-3-yl]ethanoic acid, CACODYLATE ION, HIV-1 Integrase, ...
Authors:Gupta, K, Brady, T, Dyer, B, Hwang, Y, Male, F, Nolte, R.T, Wang, L, Velthuisen, E, Jeffrey, J, Van Duyne, G, Bushman, F.D.
Deposit date:2014-01-21
Release date:2014-06-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Allosteric Inhibition of Human Immunodeficiency Virus Integrase: LATE BLOCK DURING VIRAL REPLICATION AND ABNORMAL MULTIMERIZATION INVOLVING SPECIFIC PROTEIN DOMAINS.
J.Biol.Chem., 289, 2014
1Q4G
DownloadVisualize
BU of 1q4g by Molmil
2.0 Angstrom Crystal Structure of Ovine Prostaglandin H2 Synthase-1, in complex with alpha-methyl-4-biphenylacetic acid
Descriptor: 2-(1,1'-BIPHENYL-4-YL)PROPANOIC ACID, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Gupta, K, Selinksy, B.S, Kaub, C.J, Katz, A.K, Loll, P.J.
Deposit date:2003-08-03
Release date:2004-01-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0A Resolution Crystal Structure of Prostaglandin H(2) Synthase-1: Structural Insights into an Unusual Peroxidase
J.Mol.Biol., 335, 2004
2AYL
DownloadVisualize
BU of 2ayl by Molmil
2.0 Angstrom Crystal Structure of Manganese Protoporphyrin IX-reconstituted Ovine Prostaglandin H2 Synthase-1 Complexed With Flurbiprofen
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLURBIPROFEN, GLYCEROL, ...
Authors:Gupta, K, Selinsky, B.S, Loll, P.J.
Deposit date:2005-09-07
Release date:2006-01-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:2.0 angstroms structure of prostaglandin H2 synthase-1 reconstituted with a manganese porphyrin cofactor.
Acta Crystallogr.,Sect.D, 62, 2006
8CT5
DownloadVisualize
BU of 8ct5 by Molmil
Catalytic Core Domain of HIV-1 Integrase (F185K)
Descriptor: Integrase, SULFATE ION
Authors:Gupta, K, Van Duyne, G.D, Eilers, G.
Deposit date:2022-05-13
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure of a HIV-1 IN-Allosteric inhibitor complex at 2.93 angstrom resolution: Routes to inhibitor optimization.
Plos Pathog., 19, 2023
8CT7
DownloadVisualize
BU of 8ct7 by Molmil
Catalytic Core Domain of HIV-1 Integrase (F185K) bound with BI-224436
Descriptor: (2S)-tert-butoxy[4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl]acetic acid, 1,2-ETHANEDIOL, Integrase, ...
Authors:Gupta, K, Van Duyne, G.D, Eilers, G, Bushman, F.D.
Deposit date:2022-05-13
Release date:2023-02-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structure of a HIV-1 IN-Allosteric inhibitor complex at 2.93 angstrom resolution: Routes to inhibitor optimization.
Plos Pathog., 19, 2023
8CTA
DownloadVisualize
BU of 8cta by Molmil
Minimal 2:2 Ternary Complex between BI-224436 bound HIV-1 Integrase Catalytic Core Domain Dimer and Carboxy Terminal Domains
Descriptor: (2S)-tert-butoxy[4-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2-methylquinolin-3-yl]acetic acid, 1,2-ETHANEDIOL, Integrase
Authors:Gupta, K, Van Duyne, G.D, Eilers, G, Bushman, F.D.
Deposit date:2022-05-13
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structure of a HIV-1 IN-Allosteric inhibitor complex at 2.93 angstrom resolution: Routes to inhibitor optimization.
Plos Pathog., 19, 2023
5M4S
DownloadVisualize
BU of 5m4s by Molmil
Transcription factor TFIIA as a single chain protein
Descriptor: Transcription initiation factor IIA subunit 2,Transcription initiation factor IIA subunit 1,Transcription initiation factor IIA subunit 1
Authors:Kandiah, E, Gupta, K.
Deposit date:2016-10-19
Release date:2017-11-29
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.
Elife, 6, 2017
7ODL
DownloadVisualize
BU of 7odl by Molmil
SARS CoV-2 Spike protein, Bristol UK Deletion variant, Closed conformation, C1 symmetry
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, Spike glycoprotein
Authors:Toelzer, C, Gupta, K, Yadav, S.K.N, Borucu, U, Schaffitzel, C, Berger, I.
Deposit date:2021-04-29
Release date:2022-01-26
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2.
Nat Commun, 13, 2022
7OD3
DownloadVisualize
BU of 7od3 by Molmil
SARS CoV-2 Spike protein, Bristol UK Deletion variant, Closed conformation, C3 symmetry
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, Spike glycoprotein
Authors:Toelzer, C, Gupta, K, Yadav, S.K.N, Borucu, U, Schaffitzel, C, Berger, I.
Deposit date:2021-04-28
Release date:2022-01-26
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2.
Nat Commun, 13, 2022
7ZH2
DownloadVisualize
BU of 7zh2 by Molmil
SARS CoV Spike protein, Closed C1 conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ...
Authors:Toelzer, C, Gupta, K, Yadav, S.K.N, Buzas, D, Borucu, U, Schaffitzel, C, Berger, I.
Deposit date:2022-04-05
Release date:2023-02-15
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:The free fatty acid-binding pocket is a conserved hallmark in pathogenic beta-coronavirus spike proteins from SARS-CoV to Omicron.
Sci Adv, 8, 2022
7ZH5
DownloadVisualize
BU of 7zh5 by Molmil
SARS CoV Spike protein, Open conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin
Authors:Toelzer, C, Gupta, K, Yadav, S.K.N, Buzas, D, Borucu, U, Schaffitzel, C, Berger, I.
Deposit date:2022-04-05
Release date:2023-02-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The free fatty acid-binding pocket is a conserved hallmark in pathogenic beta-coronavirus spike proteins from SARS-CoV to Omicron.
Sci Adv, 8, 2022
7ZH1
DownloadVisualize
BU of 7zh1 by Molmil
SARS CoV Spike protein, Closed C3 conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ...
Authors:Toelzer, C, Gupta, K, Yadav, S.K.N, Buzas, D, Borucu, U, Schaffitzel, C, Berger, I.
Deposit date:2022-04-05
Release date:2023-02-15
Method:ELECTRON MICROSCOPY (2.48 Å)
Cite:The free fatty acid-binding pocket is a conserved hallmark in pathogenic beta-coronavirus spike proteins from SARS-CoV to Omicron.
Sci Adv, 8, 2022
6DNW
DownloadVisualize
BU of 6dnw by Molmil
Sequence Requirements of the Listeria innocua prophage attP site
Descriptor: DNA (26-MER), Putative integrase [Bacteriophage A118], ZINC ION
Authors:Li, H, Sharp, R, Rutherford, K, Gupta, K, Van Duyne, G.D.
Deposit date:2018-06-08
Release date:2018-10-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.849 Å)
Cite:Serine Integrase attP Binding and Specificity.
J. Mol. Biol., 430, 2018
3MGV
DownloadVisualize
BU of 3mgv by Molmil
Cre recombinase-DNA transition state
Descriptor: DNA (5'-D(*CP*AP*TP*AP*TP*GP*CP*TP*AP*TP*AP*CP*GP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*CP*TP*TP*CP*GP*TP*AP*TP*AP*G)-3'), Recombinase cre, ...
Authors:Gibb, B.P, Gupta, K, Ghosh, K, Sharp, R, Chen, J, Van Duyne, G.D.
Deposit date:2010-04-07
Release date:2010-05-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Requirements for catalysis in the Cre recombinase active site.
Nucleic Acids Res., 38, 2010
8COI
DownloadVisualize
BU of 8coi by Molmil
Human adenovirus-derived synthetic ADDobody binder
Descriptor: ADDobody
Authors:Buzas, D, Toelzer, C, Gupta, K, Berger-Schaffitzel, C, Berger, I.
Deposit date:2023-02-28
Release date:2023-12-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders.
Structure, 32, 2024
6VRG
DownloadVisualize
BU of 6vrg by Molmil
Structure of HIV-1 integrase with native amino-terminal sequence
Descriptor: Integrase, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Eilers, G, Gupta, K, Allen, A, Zhou, J, Hwang, Y, Cory, M, Bushman, F.D, Van Duyne, G.D.
Deposit date:2020-02-07
Release date:2020-09-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Influence of the amino-terminal sequence on the structure and function of HIV integrase.
Retrovirology, 17, 2020
6ZB5
DownloadVisualize
BU of 6zb5 by Molmil
SARS CoV-2 Spike protein, Closed conformation, C3 symmetry
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ...
Authors:Toelzer, C, Gupta, K, Yadav, S.K.N, Burucu, U, Schaffitzel, C, Berger, I.
Deposit date:2020-06-07
Release date:2020-09-30
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein.
Science, 370, 2020
6ZB4
DownloadVisualize
BU of 6zb4 by Molmil
SARS CoV-2 Spike protein, Closed conformation, C1 symmetry
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LINOLEIC ACID, ...
Authors:Toelzer, C, Gupta, K, Yadav, S.K.N, Burucu, U, Schaffitzel, C, Berger, I.
Deposit date:2020-06-06
Release date:2020-09-30
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein.
Science, 370, 2020
1EQG
DownloadVisualize
BU of 1eqg by Molmil
THE 2.6 ANGSTROM MODEL OF OVINE COX-1 COMPLEXED WITH IBUPROFEN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IBUPROFEN, PROSTAGLANDIN H2 SYNTHASE-1, ...
Authors:Loll, P.J, Selinsky, B.S, Gupta, K, Sharkey, C.T.
Deposit date:2000-04-04
Release date:2001-04-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations.
Biochemistry, 40, 2001
1EQH
DownloadVisualize
BU of 1eqh by Molmil
THE 2.7 ANGSTROM MODEL OF OVINE COX-1 COMPLEXED WITH FLURBIPROFEN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FLURBIPROFEN, PROSTAGLANDIN H2 SYNTHASE-1, ...
Authors:Loll, P.J, Selinsky, B.S, Gupta, K, Sharkey, C.T.
Deposit date:2000-04-04
Release date:2001-04-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations.
Biochemistry, 40, 2001

 

123>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon