Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3FZN
DownloadVisualize
BU of 3fzn by Molmil
Intermediate analogue in benzoylformate decarboxylase
Descriptor: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-2-{(S)-hydroxy[(R)-hydroxy(methoxy)phosphoryl]phenylmethyl}-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium, Benzoylformate decarboxylase, CHLORIDE ION, ...
Authors:Bruning, M, Berheide, M, Meyer, D, Golbik, R, Bartunik, H, Liese, A, Tittmann, K.
Deposit date:2009-01-26
Release date:2009-05-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural and kinetic studies on native intermediates and an intermediate analogue in benzoylformate decarboxylase reveal a least motion mechanism with an unprecedented short-lived predecarboxylation intermediate.
Biochemistry, 48, 2009
2EZ8
DownloadVisualize
BU of 2ez8 by Molmil
Pyruvate oxidase variant F479W in complex with reaction intermediate 2-lactyl-thiamin diphosphate
Descriptor: 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-CARBOXY-1-HYDROXYETHYL)-5-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ...
Authors:Wille, G, Meyer, D, Steinmetz, A, Hinze, E, Golbik, R, Tittmann, K.
Deposit date:2005-11-10
Release date:2006-04-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.963 Å)
Cite:The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography.
Nat.Chem.Biol., 2, 2006
2EZ4
DownloadVisualize
BU of 2ez4 by Molmil
Pyruvate oxidase variant F479W
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Wille, G, Meyer, D, Steinmetz, A, Hinze, E, Golbik, R, Tittmann, K.
Deposit date:2005-11-10
Release date:2006-04-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography.
Nat.Chem.Biol., 2, 2006
2EZT
DownloadVisualize
BU of 2ezt by Molmil
Pyruvate oxidase variant F479W in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate
Descriptor: 2-[(2E)-3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-HYDROXYETHYLIDENE)-4-METHYL-2,3-DIHYDRO-1,3-THIAZOL-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ...
Authors:Wille, G, Meyer, D, Steinmetz, A, Hinze, E, Golbik, R, Tittmann, K.
Deposit date:2005-11-10
Release date:2006-04-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography.
Nat.Chem.Biol., 2, 2006
2EZU
DownloadVisualize
BU of 2ezu by Molmil
Pyruvate oxidase variant F479W in complex with reaction intermediate 2-acetyl-thiamin diphosphate
Descriptor: 2-ACETYL-THIAMINE DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ...
Authors:Wille, G, Meyer, D, Steinmetz, A, Hinze, E, Golbik, R, Tittmann, K.
Deposit date:2005-11-10
Release date:2006-04-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography.
Nat.Chem.Biol., 2, 2006
2EZ9
DownloadVisualize
BU of 2ez9 by Molmil
Pyruvate oxidase variant F479W in complex with reaction intermediate analogue 2-phosphonolactyl-thiamin diphosphate
Descriptor: 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ...
Authors:Wille, G, Meyer, D, Steinmetz, A, Hinze, E, Golbik, R, Tittmann, K.
Deposit date:2005-11-10
Release date:2006-04-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography.
Nat.Chem.Biol., 2, 2006
2HXX
DownloadVisualize
BU of 2hxx by Molmil
Aminotryptophan Barstar
Descriptor: Barstar
Authors:Rubini, M, Lepthien, S, Golbik, R, Budisa, N.
Deposit date:2006-08-04
Release date:2006-08-22
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Aminotryptophan-containing barstar
BIOCHIM.BIOPHYS.ACTA, 1764, 2006
1JON
DownloadVisualize
BU of 1jon by Molmil
GROEL (HSP60 CLASS) FRAGMENT COMPRISING RESIDUES 191-345
Descriptor: GROEL, HSP60 CLASS
Authors:Buckle, A.M, Fersht, A.R.
Deposit date:1996-05-30
Release date:1997-03-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Chaperone activity and structure of monomeric polypeptide binding domains of GroEL.
Proc.Natl.Acad.Sci.USA, 93, 1996
1GPU
DownloadVisualize
BU of 1gpu by Molmil
Transketolase complex with reaction intermediate
Descriptor: 2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, TRANSKETOLASE 1
Authors:Fiedler, E, Thorell, S, Sandalova, T, Koenig, S, Schneider, G.
Deposit date:2001-11-09
Release date:2002-02-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Snapshot of a Key Intermediate in Enzymatic Thiamin Catalysis: Crystal Structure of the Alpha-Carbanion of (Alpha,Beta-Dihydroxyethyl)-Thiamin Diphosphate in the Active Site of Transketolase from Saccharomyces Cerevisiae.
Proc.Natl.Acad.Sci.USA, 99, 2002
2VJY
DownloadVisualize
BU of 2vjy by Molmil
Pyruvate decarboxylase from Kluyveromyces lactis in complex with the substrate analogue methyl acetylphosphonate
Descriptor: MAGNESIUM ION, METHYL HYDROGEN (S)-ACETYLPHOSPHONATE, PYRUVATE DECARBOXYLASE, ...
Authors:Kutter, S, Wille, G, Weiss, M.S, Konig, S.
Deposit date:2007-12-14
Release date:2009-01-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Covalently Bound Substrate at the Regulatory Site of Yeast Pyruvate Decarboxylases Triggers Allosteric Enzyme Activation.
J.Biol.Chem., 284, 2009
2VK1
DownloadVisualize
BU of 2vk1 by Molmil
Crystal structure of the Saccharomyces cerevisiae pyruvate decarboxylase variant D28A in complex with its substrate
Descriptor: MAGNESIUM ION, PYRUVATE DECARBOXYLASE ISOZYME 1, PYRUVIC ACID, ...
Authors:Kutter, S, Weik, M, Weiss, M.S, Konig, S.
Deposit date:2007-12-16
Release date:2009-01-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Covalently Bound Substrate at the Regulatory Site of Yeast Pyruvate Decarboxylases Triggers Allosteric Enzyme Activation.
J.Biol.Chem., 284, 2009
2VK8
DownloadVisualize
BU of 2vk8 by Molmil
Crystal structure of the Saccharomyces cerevisiae pyruvate decarboxylase variant E477Q in complex with its substrate
Descriptor: (2S)-2-HYDROXYPROPANOIC ACID, MAGNESIUM ION, PYRUVATE DECARBOXYLASE ISOZYME 1, ...
Authors:Kutter, S, Weik, M, Weiss, M.S, Konig, S.
Deposit date:2007-12-17
Release date:2009-01-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Covalently Bound Substrate at the Regulatory Site of Yeast Pyruvate Decarboxylases Triggers Allosteric Enzyme Activation.
J.Biol.Chem., 284, 2009
3S1U
DownloadVisualize
BU of 3s1u by Molmil
Transaldolase from Thermoplasma acidophilum in complex with D-erythrose 4-phosphate
Descriptor: CHLORIDE ION, ERYTHOSE-4-PHOSPHATE, Probable transaldolase
Authors:Lehwess-Litzmann, A, Neumann, P, Parthier, C, Tittmann, K.
Deposit date:2011-05-16
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Twisted Schiff base intermediates and substrate locale revise transaldolase mechanism.
Nat.Chem.Biol., 7, 2011
3S1X
DownloadVisualize
BU of 3s1x by Molmil
Transaldolase from Thermoplasma acidophilum in complex with D-sedoheptulose 7-phosphate Schiff-base intermediate
Descriptor: D-ALTRO-HEPT-2-ULOSE 7-PHOSPHATE, Probable transaldolase
Authors:Lehwess-Litzmann, A, Neumann, P, Parthier, C, Tittmann, K.
Deposit date:2011-05-16
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Twisted Schiff base intermediates and substrate locale revise transaldolase mechanism.
Nat.Chem.Biol., 7, 2011
3S0C
DownloadVisualize
BU of 3s0c by Molmil
Transaldolase wt of Thermoplasma acidophilum
Descriptor: GLYCEROL, Probable transaldolase
Authors:Lehwess-Litzmann, A, Neumann, P, Parthier, C, Tittmann, K.
Deposit date:2011-05-13
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Twisted Schiff base intermediates and substrate locale revise transaldolase mechanism.
Nat.Chem.Biol., 7, 2011
3S1W
DownloadVisualize
BU of 3s1w by Molmil
Transaldolase variant Lys86Ala from Thermoplasma acidophilum in complex with glycerol and citrate
Descriptor: CITRATE ANION, GLYCEROL, Probable transaldolase
Authors:Lehwess-Litzmann, A, Neumann, P, Parthier, C, Tittmann, K.
Deposit date:2011-05-16
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Twisted Schiff base intermediates and substrate locale revise transaldolase mechanism.
Nat.Chem.Biol., 7, 2011
3S1V
DownloadVisualize
BU of 3s1v by Molmil
Transaldolase from Thermoplasma acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
Descriptor: FRUCTOSE -6-PHOSPHATE, GLYCEROL, Probable transaldolase
Authors:Lehwess-Litzmann, A, Neumann, P, Parthier, C, Tittmann, K.
Deposit date:2011-05-16
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Twisted Schiff base intermediates and substrate locale revise transaldolase mechanism.
Nat.Chem.Biol., 7, 2011
2R8P
DownloadVisualize
BU of 2r8p by Molmil
Transketolase from E. coli in complex with substrate D-fructose-6-phosphate
Descriptor: 1,2-ETHANEDIOL, 2-C-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-3-ium-2-yl}-6-O-phosphono-D-glucitol, CALCIUM ION, ...
Authors:Wille, G, Asztalos, P, Weiss, M.S, Tittmann, K.
Deposit date:2007-09-11
Release date:2007-12-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Strain and near attack conformers in enzymic thiamin catalysis: X-ray crystallographic snapshots of bacterial transketolase in covalent complex with donor ketoses xylulose 5-phosphate and fructose 6-phosphate, and in noncovalent complex with acceptor aldose ribose 5-phosphate.
Biochemistry, 46, 2007
2R5N
DownloadVisualize
BU of 2r5n by Molmil
Crystal structure of transketolase from Escherichia coli in noncovalent complex with acceptor aldose ribose 5-phosphate
Descriptor: 1,2-ETHANEDIOL, 5-O-phosphono-beta-D-ribofuranose, CALCIUM ION, ...
Authors:Parthier, C, Asztalos, P, Wille, G, Tittmann, K.
Deposit date:2007-09-04
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Strain and Near Attack Conformers in Enzymic Thiamin Catalysis: X-ray Crystallographic Snapshots of Bacterial Transketolase in Covalent Complex with Donor Ketoses Xylulose 5-phosphate and Fructose 6-phosphate, and in Noncovalent Complex with Acceptor Aldose Ribose 5-phosphate.
Biochemistry, 46, 2007
2R8O
DownloadVisualize
BU of 2r8o by Molmil
Transketolase from E. coli in complex with substrate D-xylulose-5-phosphate
Descriptor: 1,2-ETHANEDIOL, 2-C-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thia zol-3-ium-2-yl}-5-O-phosphono-D-xylitol, CALCIUM ION, ...
Authors:Wille, G, Asztalos, P, Weiss, M.S, Tittmann, K.
Deposit date:2007-09-11
Release date:2007-12-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Strain and near attack conformers in enzymic thiamin catalysis: X-ray crystallographic snapshots of bacterial transketolase in covalent complex with donor ketoses xylulose 5-phosphate and fructose 6-phosphate, and in noncovalent complex with acceptor aldose ribose 5-phosphate.
Biochemistry, 46, 2007
6EFH
DownloadVisualize
BU of 6efh by Molmil
Pyruvate decarboxylase from Kluyveromyces lactis soaked with pyruvamide
Descriptor: (1S,2S)-1-amino-1,2-dihydroxypropan-1-olate, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ...
Authors:Kutter, S, Konig, S.
Deposit date:2018-08-16
Release date:2018-08-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:The crystal structures of pyruvate decarboxylase from Kluyveromyces lactis in the absence of ligands and in the presence of the substrate surrogate pyruvamide
To be Published
2OZL
DownloadVisualize
BU of 2ozl by Molmil
Human pyruvate dehydrogenase S264E variant
Descriptor: MAGNESIUM ION, POTASSIUM ION, Pyruvate dehydrogenase E1 component alpha subunit, ...
Authors:Ciszak, E.M, Dominiak, P.M, Patel, M.S, Korotchkina, L.G.
Deposit date:2007-02-26
Release date:2007-05-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Phosphorylation of Serine 264 Impedes Active Site Accessibility in the E1 Component of the Human Pyruvate Dehydrogenase Multienzyme Complex
Biochemistry, 46, 2007
2Q27
DownloadVisualize
BU of 2q27 by Molmil
Crystal structure of oxalyl-coA decarboxylase from Escherichia coli
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, ...
Authors:Werther, T, Zimmer, A, Wille, G, Hubner, G, Weiss, M.S, Konig, S.
Deposit date:2007-05-26
Release date:2008-06-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:New insights into structure-function relationships of oxalyl CoA decarboxylase from Escherichia coli.
Febs J., 277, 2010
2Q29
DownloadVisualize
BU of 2q29 by Molmil
Crystal structure of oxalyl-coA decarboxylase from Escherichia coli in complex with acetyl coenzyme A
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETYL COENZYME *A, MAGNESIUM ION, ...
Authors:Werther, T, Zimmer, A, Wille, G, Hubner, G, Weiss, M.S, Konig, S.
Deposit date:2007-05-26
Release date:2008-06-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:New insights into structure-function relationships of oxalyl CoA decarboxylase from Escherichia coli.
Febs J., 277, 2010
2Q28
DownloadVisualize
BU of 2q28 by Molmil
Crystal structure of oxalyl-coA decarboxylase from Escherichia coli in complex with adenosine-5`-diphosphate
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Werther, T, Zimmer, A, Wille, G, Hubner, G, Weiss, M.S, Konig, S.
Deposit date:2007-05-26
Release date:2008-06-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:New insights into structure-function relationships of oxalyl CoA decarboxylase from Escherichia coli.
Febs J., 277, 2010

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon