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2IMU
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BU of 2imu by Molmil
NMR structure of pep46 from the infectious bursal disease virus (IBDV) in dodecylphosphocholin (DPC).
Descriptor: Structural polyprotein (PP) p1
Authors:Galloux, M, Libersou, S, Morellet, N, Bouaziz, S, Ouldali, M, Da Costa, B, Lepault, J, Delmas, B.
Deposit date:2006-10-05
Release date:2007-06-05
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Cell entry of a dsRNA virus through pores induced by one of its structural peptides.
To be Published
4BKK
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BU of 4bkk by Molmil
The Respiratory Syncytial Virus nucleoprotein-RNA complex forms a left-handed helical nucleocapsid.
Descriptor: NUCLEOPROTEIN, RNA (161-MER)
Authors:Bakker, S.E, Duquerroy, S, Galloux, M, Loney, C, Conner, E, Eleouet, J.F, Rey, F.A, Bhella, D.
Deposit date:2013-04-26
Release date:2013-10-30
Last modified:2019-04-24
Method:ELECTRON MICROSCOPY
Cite:The Respiratory Syncytial Virus Nucleoprotein-RNA Complex Forms a Left-Handed Helical Nucleocapsid.
J.Gen.Virol., 94, 2013
4UCE
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BU of 4uce by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with the Nucleoprotein Phosphoprotein interaction inhibitor M72
Descriptor: 1-[(4-fluorophenyl)methyl]pyrazole-3,5-dicarboxylic acid, NUCLEOPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC6
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BU of 4uc6 by Molmil
N-terminal globular domain of the RSV Nucleoprotein
Descriptor: NUCLEOPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC7
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BU of 4uc7 by Molmil
N-terminal globular domain of the RSV Nucleoprotein
Descriptor: NUCLEOPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCC
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BU of 4ucc by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with the Nucleoprotein Phosphoprotein interaction inhibitor M76
Descriptor: 1-[(2,4-dichlorophenyl)methyl]pyrazole-3,5-dicarboxylic acid, NUCLEOPROTEIN
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC8
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BU of 4uc8 by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal phenylalanine of the Phosphoprotein
Descriptor: GLYCEROL, NUCLEOPROTEIN, PHENYLALANINE, ...
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCA
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BU of 4uca by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal peptide of the Phosphoprotein
Descriptor: NUCLEOPROTEIN, PHOSPHOSPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCB
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BU of 4ucb by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal peptide of the Phosphoprotein
Descriptor: NUCLEOPROTEIN, PHOSPHOSPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UC9
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BU of 4uc9 by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with C- terminal dipeptide of the Phosphoprotein
Descriptor: ASPARTIC ACID, NUCLEOPROTEIN, PHENYLALANINE, ...
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
4UCD
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BU of 4ucd by Molmil
N-terminal globular domain of the RSV Nucleoprotein in complex with the Nucleoprotein Phosphoprotein interaction inhibitor M81
Descriptor: 1-[(2-chlorophenyl)methyl]pyrazole-3,5-dicarboxylic acid, NUCLEOPROTEIN, SULFATE ION
Authors:Ouizougun-Oubari, M, Pereira, N, Tarus, B, Galloux, M, Tortorici, M.-A, Hoos, S, Baron, B, England, P, Bontems, F, Rey, F.A, Eleouet, J.-F, Sizun, C, Slama-Schwok, A, Duquerroy, S.
Deposit date:2014-12-03
Release date:2015-08-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
J.Virol., 89, 2015
6YJL
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BU of 6yjl by Molmil
Solution NMR structure of the C-terminal arm of RSV nucleoprotein
Descriptor: Nucleoprotein
Authors:Cardone, C, Eleouet, J.-F, Galloux, M, Sizun, C.
Deposit date:2020-04-03
Release date:2021-04-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution NMR structure of the C-terminal arm of RSV nucleoprotein
To Be Published
8PDN
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BU of 8pdn by Molmil
Spiral of assembled human metapneumovirus (HMPV) N-RNA
Descriptor: Nucleoprotein, RNA
Authors:Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
Deposit date:2023-06-12
Release date:2023-12-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDL
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BU of 8pdl by Molmil
10-mer ring of human metapneumovirus (HMPV) N-RNA
Descriptor: Nucleoprotein, RNA
Authors:Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
Deposit date:2023-06-12
Release date:2023-12-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDR
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BU of 8pdr by Molmil
Rigid body fit of assembled HMPV N-RNA spiral bound to the C-terminal region of P
Descriptor: Nucleoprotein, Phosphoprotein, RNA
Authors:Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
Deposit date:2023-06-12
Release date:2023-12-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDO
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BU of 8pdo by Molmil
Local refinement of dimeric human metapneumovirus (HMPV) N-RNA
Descriptor: Nucleoprotein, RNA
Authors:Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
Deposit date:2023-06-12
Release date:2023-12-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDQ
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BU of 8pdq by Molmil
11-mer ring of HMPV N-RNA bound to the C-terminal region of P
Descriptor: Nucleoprotein, Phosphoprotein, RNA
Authors:Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
Deposit date:2023-06-12
Release date:2023-12-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDS
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BU of 8pds by Molmil
Local refinement of dimeric HMPV N-RNA bound to the C-terminal region of P
Descriptor: Nucleoprotein, Phosphoprotein, RNA
Authors:Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
Deposit date:2023-06-12
Release date:2023-12-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDP
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BU of 8pdp by Molmil
10-mer ring of HMPV N-RNA bound to the C-terminal region of P
Descriptor: Nucleoprotein, Phosphoprotein, RNA
Authors:Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
Deposit date:2023-06-12
Release date:2023-12-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8PDM
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BU of 8pdm by Molmil
11-mer ring of human metapneumovirus (HMPV) N-RNA
Descriptor: Nucleoprotein, RNA
Authors:Whitehead, J.D, Decool, H, Leyrat, C, Carrique, L, Fix, J, Eleouet, J.F, Galloux, M, Renner, M.
Deposit date:2023-06-12
Release date:2023-12-06
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Nat Commun, 14, 2023
8OP1
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BU of 8op1 by Molmil
Subsection of a helical nucleocapsid of the Respiratory Syncytial Virus
Descriptor: Nucleoprotein, RNA (5'-R(P*CP*CP*CP*CP*CP*CP*C)-3')
Authors:Gonnin, L, Desfosses, A, Eleouet, J.F, Galloux, M, Gutsche, I.
Deposit date:2023-04-06
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural landscape of the respiratory syncytial virus nucleocapsids.
Nat Commun, 14, 2023
8PHI
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BU of 8phi by Molmil
Crystal structure of prefusion-stabilized RSV F Variant DS-Cav1 in complex with Lonafarnib
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, 4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE, CALCIUM ION, ...
Authors:Rajak, M, Krey, T.
Deposit date:2023-06-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.289 Å)
Cite:Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor.
Nat Commun, 15, 2024
6S3D
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BU of 6s3d by Molmil
Structure of D25 Fab in complex with scaffold S0_2.126
Descriptor: Heavy Chain, Light Chain, S0_2.126
Authors:Cramer, J.T, Krey, T.
Deposit date:2019-06-25
Release date:2020-04-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:De novo protein design enables the precise induction of RSV-neutralizing antibodies.
Science, 368, 2020
6YP5
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BU of 6yp5 by Molmil
Solution NMR structure of the oligomerization domain of respiratory syncytial virus phosphoprotein
Descriptor: Phosphoprotein
Authors:Cardone, C, Bontems, F, Bardiaux, B, Sizun, C.
Deposit date:2020-04-15
Release date:2021-04-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Structural and Dynamic Analysis of the Partially Disordered Polymerase-Binding Domain in RSV Phosphoprotein.
Biomolecules, 11, 2021
6VTW
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BU of 6vtw by Molmil
De novo protein design enables the precise induction of RSV-neutralizing antibodies
Descriptor: 101F Fab Heavy Chain, 101F Fab Light Chain, S4_2.45
Authors:Jardetzky, T, Correia, B.
Deposit date:2020-02-13
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:De novo protein design enables the precise induction of RSV-neutralizing antibodies.
Science, 368, 2020

 

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