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4AO8
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BU of 4ao8 by Molmil
PEG-bound complex of a novel cold-adapted esterase from an Arctic intertidal metagenomic library
Descriptor: DI(HYDROXYETHYL)ETHER, ESTERASE
Authors:Fu, J, Leiros, H.-K.S, Pascale, D.d, Johnson, K.A, Blencke, H.M, Landfald, B.
Deposit date:2012-03-23
Release date:2012-08-08
Last modified:2013-05-01
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Functional and Structural Studies of a Novel Cold-Adapted Esterase from an Arctic Intertidal Metagenomic Library.
Appl.Microbiol.Biotechnol., 97, 2013
4AO6
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BU of 4ao6 by Molmil
Native structure of a novel cold-adapted esterase from an Arctic intertidal metagenomic library
Descriptor: ESTERASE
Authors:Fu, J, Leiros, H.-K.S, Pascale, D.d, Johnson, K.A, Blencke, H.M, Landfald, B.
Deposit date:2012-03-23
Release date:2012-08-08
Last modified:2013-05-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Functional and Structural Studies of a Novel Cold-Adapted Esterase from an Arctic Intertidal Metagenomic Library.
Appl.Microbiol.Biotechnol., 97, 2013
4AO7
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BU of 4ao7 by Molmil
Zinc bound structure of a novel cold-adapted esterase from an Arctic intertidal metagenomic library
Descriptor: ESTERASE, ZINC ION
Authors:Fu, J, Leiros, H.-K.S, Pascale, D.d, Johnson, K.A, Blencke, H.M, Landfald, B.
Deposit date:2012-03-23
Release date:2012-08-08
Last modified:2013-05-01
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Functional and Structural Studies of a Novel Cold-Adapted Esterase from an Arctic Intertidal Metagenomic Library.
Appl.Microbiol.Biotechnol., 97, 2013
7T9P
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BU of 7t9p by Molmil
Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain native virion
Descriptor: viral protein 1, viral protein 2, viral protein 3, ...
Authors:Fu, J, Klose, T, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-12-19
Release date:2023-01-25
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68
To Be Published
7TAF
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BU of 7taf by Molmil
Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with inhibitor 11526092
Descriptor: N,N-dimethyl-5-(3-{2-methyl-4-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenoxy}propyl)-1,2-oxazole-3-carboxamide, viral protein 1, viral protein 2, ...
Authors:Fu, J, Klose, T, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-12-20
Release date:2023-01-25
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68
To Be Published
7TAH
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BU of 7tah by Molmil
Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain in complex with inhibitor 11526091 (no/low occupancy-no inhibitor modeled)
Descriptor: viral protein 1, viral protein 2, viral protein 3, ...
Authors:Fu, J, Klose, T, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-12-20
Release date:2023-01-25
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68
To Be Published
7TAJ
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BU of 7taj by Molmil
Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain in complex with inhibitor 11526093 (no/low occupancy-no inhibitor modeled)
Descriptor: viral protein 1, viral protein 2, viral protein 3, ...
Authors:Fu, J, Klose, T, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-12-20
Release date:2023-01-25
Method:ELECTRON MICROSCOPY (2 Å)
Cite:Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68
To Be Published
7TAG
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BU of 7tag by Molmil
Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain virion in complex with pleconaril
Descriptor: 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, viral protein 1, viral protein 2, ...
Authors:Fu, J, Klose, T, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2021-12-20
Release date:2023-01-25
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68
To Be Published
3IZ4
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BU of 3iz4 by Molmil
Modified E. coli tmRNA in the resume state with the tRNA-like domain in the ribosomal P site interacting with the SmpB
Descriptor: Modified E. coli transfer-messenger RNA, SsrA-binding protein
Authors:Hashem, Y, Fu, J, Frank, J.
Deposit date:2010-09-21
Release date:2010-10-20
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (13.6 Å)
Cite:Visualizing the transfer-messenger RNA as the ribosome resumes translation.
Embo J., 29, 2010
6WDT
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BU of 6wdt by Molmil
Enterovirus D68 in complex with human monoclonal antibody EV68-228
Descriptor: EV68-228 heavy chain, EV68-228 light chain, viral protein 1, ...
Authors:Fu, J, Vogt, M.R, Klose, T, Crowe, J.E, Rossmann, M.G, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-04-01
Release date:2020-07-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease.
Sci Immunol, 5, 2020
6WDS
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BU of 6wds by Molmil
Enterovirus D68 in complex with human monoclonal antibody EV68-159
Descriptor: EV68-159 heavy chain, EV68-159 light chain, viral protein 1, ...
Authors:Fu, J, Klose, T, Vogt, M.R, Crowe, J.E, Rossmann, M.G, Kuhn, R.J, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-04-01
Release date:2020-07-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease.
Sci Immunol, 5, 2020
4V8M
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BU of 4v8m by Molmil
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
Descriptor: 18S RRNA OF THE SMALL RIBOSOMAL SUBUNIT, 40S RIBOSOMAL PROTEIN S10, PUTATIVE, ...
Authors:Hashem, Y, des Georges, A, Fu, J, Buss, S.N, Jossinet, F, Jobe, A, Zhang, Q, Liao, H.Y, Grassucci, R.A, Bajaj, C, Westhof, E, Madison-Antenucci, S, Frank, J.
Deposit date:2012-12-09
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5.57 Å)
Cite:High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.
Nature, 494, 2013
4V6R
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BU of 4v6r by Molmil
Structural characterization of mRNA-tRNA translocation intermediates (class 6 of the six classes)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
Deposit date:2011-12-08
Release date:2014-07-09
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V6N
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BU of 4v6n by Molmil
Structural characterization of mRNA-tRNA translocation intermediates (50S ribosome of class2 of the six classes)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
Deposit date:2011-12-07
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (12.1 Å)
Cite:Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V6S
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BU of 4v6s by Molmil
Structural characterization of mRNA-tRNA translocation intermediates (class 3 of the six classes)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
Deposit date:2011-12-09
Release date:2014-07-09
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (13.1 Å)
Cite:Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V6O
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BU of 4v6o by Molmil
Structural characterization of mRNA-tRNA translocation intermediates (class 4a of the six classes)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
Deposit date:2011-12-07
Release date:2014-07-09
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (14.7 Å)
Cite:Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
2B8K
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BU of 2b8k by Molmil
12-subunit RNA Polymerase II
Descriptor: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ...
Authors:Meyer, P.A, Ye, P, Zhang, M, Suh, M.H, Fu, J.
Deposit date:2005-10-07
Release date:2006-06-20
Last modified:2012-06-13
Method:X-RAY DIFFRACTION (4.15 Å)
Cite:Phasing RNA Polymerase II Using Intrinsically Bound Zn Atoms: An Updated Structural Model.
Structure, 14, 2006
4V6Q
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BU of 4v6q by Molmil
Structural characterization of mRNA-tRNA translocation intermediates (class 5 of the six classes)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
Deposit date:2011-12-08
Release date:2014-07-09
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V6P
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BU of 4v6p by Molmil
Structural characterization of mRNA-tRNA translocation intermediates (class 4b of the six classes)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J.
Deposit date:2011-12-08
Release date:2014-07-09
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (13.5 Å)
Cite:Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
3FKI
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BU of 3fki by Molmil
12-Subunit RNA Polymerase II Refined with Zn-SAD data
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Meyer, P.A, Ye, P, Suh, M.H, Zhang, M, Fu, J.
Deposit date:2008-12-16
Release date:2009-03-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.88 Å)
Cite:Structure of the 12-Subunit RNA Polymerase II Refined with the Aid of Anomalous Diffraction Data
J.Biol.Chem., 284, 2009
4YTL
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BU of 4ytl by Molmil
Structure of the KOW2-KOW3 Domain of Transcription Elongation Factor Spt5.
Descriptor: GLYCEROL, SULFATE ION, Transcription elongation factor SPT5
Authors:Meyer, P.A, Li, S, ZHang, M, Yamada, K, Takagi, Y, Hartzog, G.A, Fu, J.
Deposit date:2015-03-17
Release date:2015-08-12
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structures and Functions of the Multiple KOW Domains of Transcription Elongation Factor Spt5.
Mol.Cell.Biol., 35, 2015
4YTK
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BU of 4ytk by Molmil
Structure of the KOW1-Linker1 domain of Transcription Elongation Factor Spt5
Descriptor: Transcription elongation factor SPT5
Authors:Meyer, P.A, Li, S, Zhang, M, Yamada, K, Takagi, Y, Hartzog, G.A, Fu, J.
Deposit date:2015-03-17
Release date:2015-08-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.0904 Å)
Cite:Structures and Functions of the Multiple KOW Domains of Transcription Elongation Factor Spt5.
Mol.Cell.Biol., 35, 2015
3LD1
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BU of 3ld1 by Molmil
Crystal Structure of IBV Nsp2a
Descriptor: Replicase polyprotein 1a
Authors:Xu, Y, Cong, L, Wei, L, Fu, J, Chen, C, Yang, A, Tang, H, Bartlam, M, Rao, Z.
Deposit date:2010-01-12
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.498 Å)
Cite:IBV nsp2 is an endosome-associated protein and viral pathogenicity factor
To be Published
4TOT
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BU of 4tot by Molmil
Crystal structure of rat cyclophilin D in complex with a potent nonimmunosuppressive inhibitor
Descriptor: HEXAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ...
Authors:Knapp, M.S, Elling, R.A.
Deposit date:2014-06-06
Release date:2014-11-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.
J.Med.Chem., 57, 2014
7W3S
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BU of 7w3s by Molmil
The complex structure of Larg1-ADPr from Legionella pneumophila
Descriptor: Type IV secretion protein Dot, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Ouyang, S, Guan, H, Li, P.
Deposit date:2021-11-26
Release date:2022-04-06
Last modified:2022-05-18
Method:X-RAY DIFFRACTION (2.324 Å)
Cite:Legionella pneumophila temporally regulates the activity of ADP/ATP translocases by reversible ADP-ribosylation.
mLife, 2022

 

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