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6SWG
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BU of 6swg by Molmil
Crystal structure of the TASOR-Periphilin core complex
Descriptor: Periphilin-1, Protein TASOR, SULFATE ION
Authors:Prigozhin, D.M, Freund, S.M.V, Modis, Y.
Deposit date:2019-09-20
Release date:2020-08-05
Last modified:2020-10-21
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Periphilin self-association underpins epigenetic silencing by the HUSH complex.
Nucleic Acids Res., 48, 2020
6TL1
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BU of 6tl1 by Molmil
Crystal structure of the TASOR pseudo-PARP domain
Descriptor: GLYCEROL, Protein TASOR
Authors:Douse, C.H, Timms, R.T, Freund, S.M.V, Modis, Y.
Deposit date:2019-11-29
Release date:2020-09-16
Last modified:2020-10-14
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control.
Nat Commun, 11, 2020
3ZHF
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BU of 3zhf by Molmil
gamma 2 adaptin EAR domain crystal structure with preS1 site1 peptide NPDWDFN
Descriptor: 1,2-ETHANEDIOL, AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2, DI(HYDROXYETHYL)ETHER, ...
Authors:Juergens, M.C, Voros, J, Rautureau, G, Shepherd, D, Pye, V.E, Muldoon, J, Johnson, C.M, Ashcroft, A, Freund, S.M.V, Ferguson, N.
Deposit date:2012-12-21
Release date:2013-07-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Hepatitis B Virus Pres1 Domain Hijacks Host Trafficking Proteins by Motif Mimicry.
Nat.Chem.Biol., 9, 2013
4UZX
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BU of 4uzx by Molmil
High-resolution NMR structures of the domains of Saccharomyces cerevisiae Tho1
Descriptor: PROTEIN THO1
Authors:Jacobsen, J.O.B, Allen, M.D, Freund, S.M.V, Bycroft, M.
Deposit date:2014-09-09
Release date:2014-12-17
Last modified:2016-06-29
Method:SOLUTION NMR
Cite:High-Resolution NMR Structures of the Domains of Saccharomyces Cerevisiae Tho1.
Acta Crystallogr.,Sect.F, 72, 2016
4UZW
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BU of 4uzw by Molmil
High-resolution NMR structures of the domains of Saccharomyces cerevisiae Tho1
Descriptor: PROTEIN THO1
Authors:Jacobsen, J.O.B, Allen, M.D, Freund, S.M.V, Bycroft, M.
Deposit date:2014-09-09
Release date:2014-12-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:High-Resolution NMR Structures of the Domains of Saccharomyces Cerevisiae Tho1.
Acta Crystallogr.,Sect.F, 72, 2016
1H1J
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BU of 1h1j by Molmil
The SAP domain is a DNA-Binding Domain Capable of Binding S/MAR DNA
Descriptor: THO1 PROTEIN
Authors:Jacobsen, J.O.B, Freund, S.M.V, Bycroft, M.
Deposit date:2002-07-16
Release date:2002-08-08
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:The Sap Domain is a DNA-Binding Domain Capable of Binding S/Mar DNA
To be Published
5AF4
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BU of 5af4 by Molmil
Structure of Lys33-linked diUb
Descriptor: GLYCEROL, SULFATE ION, UBIQUITIN
Authors:Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
Deposit date:2015-01-19
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
5AJ1
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BU of 5aj1 by Molmil
Solution Structure of the Smarc Domain
Descriptor: SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY B MEMBER 1
Authors:Allen, M.D, Freund, S.M.V, Zinzalla, G, Bycroft, M.
Deposit date:2015-02-19
Release date:2015-08-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Swi/Snf Subunit Ini1 Contains an N-Terminal Winged Helix DNA Binding Domain that is a Target for Mutations in Schwannomatosis.
Structure, 23, 2015
5AF6
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BU of 5af6 by Molmil
Structure of Lys33-linked diUb bound to Trabid NZF1
Descriptor: TRABID, UBIQUITIN, ZINC ION
Authors:Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
Deposit date:2015-01-19
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
5AF5
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BU of 5af5 by Molmil
Structure of Lys33-linked triUb S.G. P 212121
Descriptor: POLYUBIQUITIN-C
Authors:Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
Deposit date:2015-01-19
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
6EQI
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BU of 6eqi by Molmil
Structure of PINK1 bound to ubiquitin
Descriptor: GLYCEROL, Nb696, Serine/threonine-protein kinase PINK1, ...
Authors:Schubert, A.F, Gladkova, C, Pardon, E, Wagstaff, J.L, Freund, S.M.V, Steyaert, J, Maslen, S, Komander, D.
Deposit date:2017-10-13
Release date:2017-11-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of PINK1 in complex with its substrate ubiquitin.
Nature, 552, 2017
6FPP
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BU of 6fpp by Molmil
Structure of S. pombe Mmi1
Descriptor: GLYCEROL, MAGNESIUM ION, YTH domain-containing protein mmi1
Authors:Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
Deposit date:2018-02-11
Release date:2018-05-09
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
6FPQ
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BU of 6fpq by Molmil
Structure of S. pombe Mmi1 in complex with 7-mer RNA
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, RNA (5'-R(*UP*UP*AP*AP*AP*CP*C)-3'), YTH domain-containing protein mmi1
Authors:Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
Deposit date:2018-02-11
Release date:2018-05-09
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
6FPX
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BU of 6fpx by Molmil
Structure of S. pombe Mmi1 in complex with 11-mer RNA
Descriptor: GLYCEROL, RNA (5'-R(P*UP*UP*UP*AP*AP*AP*CP*CP*UP*A)-3'), YTH domain-containing protein mmi1
Authors:Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A.
Deposit date:2018-02-12
Release date:2018-05-09
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.
J. Biol. Chem., 293, 2018
2V0E
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BU of 2v0e by Molmil
BRK domain from human CHD7
Descriptor: CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7
Authors:Allen, M.D, Religa, T.L, Freund, S.M.V, Bycroft, M.
Deposit date:2007-05-14
Release date:2007-05-22
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Solution Structure of the Brk Domains from Chd7
J.Mol.Biol., 371, 2007
2V0F
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BU of 2v0f by Molmil
BRK domain from human CHD7
Descriptor: CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7
Authors:Allen, M.D, Religa, T.L, Freund, S.M.V, Bycroft, M.
Deposit date:2007-05-14
Release date:2007-05-22
Last modified:2018-01-24
Method:SOLUTION NMR
Cite:Solution Structure of the Brk Domains from Chd7
J.Mol.Biol., 371, 2007
2VYT
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BU of 2vyt by Molmil
The MBT repeats of human SCML2 bind to peptides containing mono methylated lysine.
Descriptor: N-METHYL-LYSINE, SEX COMB ON MIDLEG-LIKE PROTEIN 2, TRIETHYLENE GLYCOL
Authors:Santiveri, C.M, Lechtenberg, B.C, Allen, M.D, Sathyamurthy, A, Jaulent, A.M, Freund, S.M.V, Bycroft, M.
Deposit date:2008-07-28
Release date:2008-08-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Malignant Brain Tumor Repeats of Human Scml2 Bind to Peptides Containing Monomethylated Lysine.
J.Mol.Biol., 382, 2008
2X4X
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BU of 2x4x by Molmil
Molecular basis of Histone H3K36me3 recognition by the PWWP domain of BRPF1.
Descriptor: HISTONE H3.2, PEREGRIN, SULFATE ION
Authors:Vezzoli, A, Bonadies, N, Allen, M.D, Freund, S.M.V, Santiveri, C.M, Kvinlaug, B, Huntly, B.J.P, Gottgens, B, Bycroft, M.
Deposit date:2010-02-02
Release date:2010-04-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
Nat.Struct.Mol.Biol., 17, 2010
2X35
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BU of 2x35 by Molmil
Molecular basis of Histone H3K36me3 recognition by the PWWP domain of BRPF1.
Descriptor: PEREGRIN
Authors:Vezzoli, A, Bonadies, N, Allen, M.D, Freund, S.M.V, Santiveri, C.M, Kvinlaug, B, Huntly, B.J.P, Gottgens, B, Bycroft, M.
Deposit date:2010-01-21
Release date:2010-02-02
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
Nat.Struct.Mol.Biol., 17, 2010
2X4W
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BU of 2x4w by Molmil
Molecular basis of Histone H3K36me3 recognition by the PWWP domain of BRPF1.
Descriptor: FORMIC ACID, HISTONE H3.2, PEREGRIN
Authors:Vezzoli, A, Bonadies, N, Allen, M.D, Freund, S.M.V, Santiveri, C.M, Kvinlaug, B, Huntly, B.J.P, Gottgens, B, Bycroft, M.
Deposit date:2010-02-02
Release date:2010-04-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
Nat.Struct.Mol.Biol., 17, 2010
2X4Y
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BU of 2x4y by Molmil
Molecular basis of Histone H3K36me3 recognition by the PWWP domain of BRPF1.
Descriptor: HISTONE H3.2, PEREGRIN, SULFATE ION
Authors:Vezzoli, A, Bonadies, N, Allen, M.D, Freund, S.M.V, Santiveri, C.M, Kvinlaug, B, Huntly, B.J.P, Gottgens, B, Bycroft, M.
Deposit date:2010-02-02
Release date:2010-04-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Basis of Histone H3K36Me3 Recognition by the Pwwp Domain of Brpf1.
Nat.Struct.Mol.Biol., 17, 2010
2XEW
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BU of 2xew by Molmil
Crystal structure of K11-linked diubiquitin
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CITRATE ANION, ...
Authors:Bremm, A, Freund, S.M.V, Komander, D.
Deposit date:2010-05-18
Release date:2010-07-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Lys11-Linked Ubiquitin Chains Adopt Compact Conformations and are Preferentially Hydrolyzed by the Deubiquitinase Cezanne
Nat.Struct.Mol.Biol., 17, 2010
2Y9U
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BU of 2y9u by Molmil
Structural basis of p63a SAM domain mutants involved in AEC syndrome
Descriptor: SULFATE ION, TUMOR PROTEIN 63
Authors:Sathyamurthy, A, Freund, S.M.V, Johnson, C.M, Allen, M.D.
Deposit date:2011-02-16
Release date:2011-08-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis of P63Alpha Sam Domain Mutants Involved in Aec Syndrome.
FEBS J., 278, 2011
2Y9T
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BU of 2y9t by Molmil
Structural basis of p63a SAM domain mutants involved in AEC syndrome
Descriptor: TUMOR PROTEIN 63
Authors:Sathyamurthy, A, Freund, S.M.V, Johnson, C.M, Allen, M.D.
Deposit date:2011-02-16
Release date:2011-08-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis of P63Alpha Sam Domain Mutants Involved in Aec Syndrome.
FEBS J., 278, 2011
2YMT
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BU of 2ymt by Molmil
gamma 2 adaptin EAR domain crystal structure with phage peptide GEEWGPWV
Descriptor: 1,3-PROPANDIOL, AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2, PHAGE DISPLAY DERIVED GAMMA 2 ADAPTIN EAR DOMAIN BINDING PEPTIDE
Authors:Juergens, M.C, Voros, J, Rautureau, G, Shepherd, D, Pye, V.E, Muldoon, J, Johnson, C.M, Ashcroft, A, Freund, S.M.V, Ferguson, N.
Deposit date:2012-10-10
Release date:2013-07-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:The Hepatitis B Virus Pres1 Domain Hijacks Host Trafficking Proteins by Motif Mimicry.
Nat.Chem.Biol., 9, 2013

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