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8AXO
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BU of 8axo by Molmil
Crystal structure of the C-terminal domain of Trypanosoma brucei CFAP410
Descriptor: TbCFAP410-CTD
Authors:Dong, G, Stadler, A.
Deposit date:2022-08-31
Release date:2023-09-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Structural studies of cilia and flagella associated protein 410 (CFAP410) reveal its bimodular organization with an N-terminal LRR motif and a C-terminal tetrameric helical bundle
To Be Published
8AXR
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BU of 8axr by Molmil
Crystal structure of the C-terminal domain of human CFAP410
Descriptor: CHLORIDE ION, Cilia- and flagella-associated protein 410
Authors:Dong, G, Stadler, A.
Deposit date:2022-08-31
Release date:2023-09-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural studies of cilia and flagella associated protein 410 (CFAP410) reveal its bimodular organization with an N-terminal LRR motif and a C-terminal tetrameric helical bundle
To Be Published
8AXJ
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BU of 8axj by Molmil
Crystal structure of the N-terminal domain of Trypanosoma brucei CFAP410
Descriptor: Chains: A, GLYCEROL, PHOSPHATE ION
Authors:Dong, G, Stadler, A.
Deposit date:2022-08-31
Release date:2023-09-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structural studies of cilia and flagella associated protein 410 (CFAP410) reveal its bimodular organization with an N-terminal LRR motif and a C-terminal tetrameric helical bundle
To Be Published
1K8H
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BU of 1k8h by Molmil
NMR Structure of Small Protein B (SmpB) from Aquifex aeolicus
Descriptor: Small protein B
Authors:Dong, G, Hoffman, D.W.
Deposit date:2001-10-24
Release date:2002-03-20
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structure of small protein B: the protein component of the tmRNA-SmpB system for ribosome rescue.
EMBO J., 21, 2002
1S29
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BU of 1s29 by Molmil
La autoantigen N-terminal domain
Descriptor: La protein
Authors:Dong, G, Chakshusmathi, G, Wolin, S.L, Reinisch, K.M.
Deposit date:2004-01-08
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the La motif: a winged helix domain mediates RNA binding via a conserved aromatic patch.
Embo J., 23, 2004
3F8U
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BU of 3f8u by Molmil
Tapasin/ERp57 heterodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein disulfide-isomerase A3ERp57, Tapasin
Authors:Dong, G, Reinisch, K.M.
Deposit date:2008-11-13
Release date:2009-01-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights into MHC class I peptide loading from the structure of the tapasin-ERp57 thiol oxidoreductase heterodimer.
Immunity, 30, 2009
2B1E
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BU of 2b1e by Molmil
The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif
Descriptor: Exocyst complex component EXO70
Authors:Dong, G, Hutagalung, A.H, Fu, C, Novick, P, Reinisch, K.M.
Deposit date:2005-09-15
Release date:2005-11-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif
Nat.Struct.Mol.Biol., 12, 2005
2D2S
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BU of 2d2s by Molmil
Crystal Structure of the Exo84p C-terminal Domains
Descriptor: Exocyst complex component EXO84
Authors:Dong, G, Hutagalung, A.H, Fu, C, Novick, P, Reinisch, K.M.
Deposit date:2005-09-16
Release date:2005-11-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The structures of exocyst subunit Exo70p and the Exo84p C-terminal domains reveal a common motif
Nat.Struct.Mol.Biol., 12, 2005
8AY2
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BU of 8ay2 by Molmil
Crystal structure of the C-terminal part of rat Sec8
Descriptor: Exocyst complex component 4
Authors:Dong, G, Lesigang, J.
Deposit date:2022-09-01
Release date:2023-09-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Sec8 specifically interacts with the PDZ2 domain of synapse associated protein 102 (SAP102).
Front Cell Dev Biol, 11, 2023
7A1R
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BU of 7a1r by Molmil
Crystal structure of the C2B domain of Trypanosoma brucei extended synaptotagmin (E-Syt)
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Dong, G.
Deposit date:2020-08-13
Release date:2021-06-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural studies of the shortest extended synaptotagmin with only two C2 domains from Trypanosoma brucei .
Iscience, 24, 2021
7A1I
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BU of 7a1i by Molmil
Crystal structure of the BILBO2/FPC4 complex
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BILBO1_N domain-containing protein, ...
Authors:Dong, G.
Deposit date:2020-08-13
Release date:2021-07-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural and functional studies of the first tripartite protein complex at the Trypanosoma brucei flagellar pocket collar.
Plos Pathog., 17, 2021
2OCY
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BU of 2ocy by Molmil
Complex of the guanine exchange factor Sec2p and the Rab GTPase Sec4p
Descriptor: Rab guanine nucleotide exchange factor SEC2, Ras-related protein SEC4
Authors:Reinisch, K.M, Dong, G.
Deposit date:2006-12-21
Release date:2007-02-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A Catalytic Coiled Coil: Structural Insights into the Activation of the Rab GTPase Sec4p by Sec2p.
Mol.Cell, 25, 2007
4NK7
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BU of 4nk7 by Molmil
Crystal Structure of the D. melanogaster Plk4 cryptic polo box (CPB)
Descriptor: Serine/threonine-protein kinase PLK4
Authors:Dong, G, Lesigang, J.
Deposit date:2013-11-12
Release date:2014-08-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.233 Å)
Cite:Structure of the C. elegans ZYG-1 Cryptic Polo Box Suggests a Conserved Mechanism for Centriolar Docking of Plk4 Kinases.
Structure, 22, 2014
7Q83
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BU of 7q83 by Molmil
Crystal structure of S. cerevisiae Sso2 in complex with the pleckstrin homology domain of Sec3
Descriptor: Exocyst complex component SEC3, Protein SSO2
Authors:Zhang, Y, Dong, G.
Deposit date:2021-11-09
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Double NPY motifs at the N-terminus of the yeast t-SNARE Sso2 synergistically bind Sec3 to promote membrane fusion.
Elife, 11, 2022
2MEK
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BU of 2mek by Molmil
N-terminal domain of Bilbo1 from Trypanosoma brucei
Descriptor: N-TERMINAL DOMAIN OF BILBO1
Authors:Vidilaseris, K, Morriswood, B, Kontaxis, G, Dong, G.
Deposit date:2013-09-24
Release date:2014-01-01
Method:SOLUTION NMR
Cite:Structure and assembly mechanism of TbBILBO1, an essential flagellar pocket collar protein
To be Published
5LG4
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BU of 5lg4 by Molmil
Crystal structure of the Sec3/Sso2 complex at 2.9 angstrom resolution
Descriptor: Exocyst complex component SEC3, Protein SSO2, SULFATE ION
Authors:Zhang, Y.B, Dong, G.
Deposit date:2016-07-05
Release date:2017-02-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion.
Nat Commun, 8, 2017
5M4Y
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BU of 5m4y by Molmil
Crystal structure of the Sec3/Sso2 complex at 2.20 angstrom resolution
Descriptor: Exocyst complex component SEC3, GLYCEROL, Protein SSO2
Authors:Zhang, Y.B, Dong, G.
Deposit date:2016-10-19
Release date:2017-02-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion.
Nat Commun, 8, 2017
6SJQ
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BU of 6sjq by Molmil
1.7-A resolution crystal structure of the N-terminal domain of T. brucei BILBO1
Descriptor: Flagellar pocket-related cytoskeletal protein, GLYCEROL
Authors:Vidilaseris, K, Dong, G.
Deposit date:2019-08-13
Release date:2020-01-01
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (1.604 Å)
Cite:Crystal structure of the N-terminal domain of the trypanosome flagellar protein BILBO1 reveals a ubiquitin fold with a long structured loop for protein binding.
J.Biol.Chem., 295, 2020
3K53
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BU of 3k53 by Molmil
Crystal Structure of NFeoB from P. furiosus
Descriptor: Ferrous iron transport protein b
Authors:Eng, E.T, Dong, G, Unger, V.M.
Deposit date:2009-10-06
Release date:2010-05-26
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural fold, conservation and Fe(II) binding of the intracellular domain of prokaryote FeoB.
J.Struct.Biol., 170, 2010
4GKW
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BU of 4gkw by Molmil
Crystal Structure of the Coiled-coil Domain of C. elegans SAS-6
Descriptor: Spindle assembly abnormal protein 6
Authors:Qiao, R, Dong, G.
Deposit date:2012-08-13
Release date:2012-11-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:SAS-6 coiled-coil structure and interaction with SAS-5 suggest a regulatory mechanism in C. elegans centriole assembly.
Embo J., 31, 2012
6FND
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BU of 6fnd by Molmil
Crystal structure of Toxoplasma gondii AKMT
Descriptor: 1,2-ETHANEDIOL, Apical complex lysine methyltransferase, DI(HYDROXYETHYL)ETHER, ...
Authors:Pivovarova, Y, Dong, G.
Deposit date:2018-02-02
Release date:2018-11-14
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structure of a Novel Dimeric SET Domain Methyltransferase that Regulates Cell Motility.
J. Mol. Biol., 430, 2018
4NKB
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BU of 4nkb by Molmil
Crystal Structure of the cryptic polo box (CPB)of ZYG-1
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ...
Authors:Shimanovskaya, E, Dong, G.
Deposit date:2013-11-12
Release date:2014-08-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the C. elegans ZYG-1 Cryptic Polo Box Suggests a Conserved Mechanism for Centriolar Docking of Plk4 Kinases.
Structure, 22, 2014
7U1M
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BU of 7u1m by Molmil
Crystal structure of NTMT1 in complex with compound YD206
Descriptor: (1R,3S,4R)-1-azabicyclo[2.2.2]octan-3-yl {2-[2-(4-fluorophenyl)-1,3-thiazol-4-yl]propan-2-yl}carbamate, N-terminal Xaa-Pro-Lys N-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Yadav, R, Noinaj, N.
Deposit date:2022-02-21
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Venglustat Inhibits Protein N-Terminal Methyltransferase 1 in a Substrate-Competitive Manner.
J.Med.Chem., 65, 2022
6WJ7
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BU of 6wj7 by Molmil
The structure of NTMT1 in complex with compound C2A
Descriptor: AN6-GLZ-PRO-LYS-ARG-ILE-ALA-NH2, N-terminal Xaa-Pro-Lys N-methyltransferase 1
Authors:Srinivasan, K, Chen, D, Huang, R, Noinaj, N.
Deposit date:2020-04-13
Release date:2020-08-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Probing the Plasticity in the Active Site of Protein N-terminal Methyltransferase 1 Using Bisubstrate Analogues.
J.Med.Chem., 63, 2020
6WH8
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BU of 6wh8 by Molmil
The structure of NTMT1 in complex with compound BM-30
Descriptor: 4HP-PRO-LYS-ARG-NH2, BM-30, N-terminal Xaa-Pro-Lys N-methyltransferase 1, ...
Authors:Noinaj, N, Chen, D, Huang, R.
Deposit date:2020-04-07
Release date:2020-08-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.729 Å)
Cite:Selective Peptidomimetic Inhibitors of NTMT1/2: Rational Design, Synthesis, Characterization, and Crystallographic Studies.
J.Med.Chem., 63, 2020

 

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