1J8S
 
 | | PAPG ADHESIN RECEPTOR BINDING DOMAIN-UNBOUND FORM | | Descriptor: | PYELONEPHRITIC ADHESIN | | Authors: | Dodson, K.W, Pinkner, J.S, Rose, T, Magnusson, G, Hultgren, S.J, Waksman, G. | | Deposit date: | 2001-05-22 | | Release date: | 2001-06-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor.
Cell(Cambridge,Mass.), 105, 2001
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1J8R
 | | BINARY COMPLEX OF THE PAPG RECEPTOR-BINDING DOMAIN BOUND TO GBO4 RECEPTOR | | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PYELONEPHRITIC ADHESIN | | Authors: | Dodson, K.W, Pinkner, J.S, Rose, T, Magnusson, G, Hultgren, S.J, Waksman, G, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2001-05-22 | | Release date: | 2001-06-22 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor.
Cell(Cambridge,Mass.), 105, 2001
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8DEZ
 | | Abp2D Receptor Binding Domain ACICU | | Descriptor: | Abp2D Receptor Binding Domain, CITRATE ANION, SULFATE ION | | Authors: | Tamadonfar, K.O, Pinkner, J.P, Dodson, K.W, Kalas, V, Hultgren, S.J. | | Deposit date: | 2022-06-21 | | Release date: | 2023-03-01 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.29 Å) | | Cite: | Structure-function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8DKA
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8DF0
 | | Abp1D receptor binding domain | | Descriptor: | Abp1D Receptor Binding Domain | | Authors: | Tamadonfar, K.O, Pinkner, J.S, Dodson, K.W, Hultgren, S.J. | | Deposit date: | 2022-06-21 | | Release date: | 2023-03-01 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure-function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections.
Proc.Natl.Acad.Sci.USA, 120, 2023
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5LNG
 | | Lectin domain of E. coli F9 pilus adhesin FmlH | | Descriptor: | Putative Fml fimbrial adhesin FmlD, SULFATE ION | | Authors: | Ruer, S, Conover, M.S, Kalas, V, Taganna, J, De Greve, H, Pinkner, J.S, Dodson, K.W, Hultgren, S.J, Remaut, H. | | Deposit date: | 2016-08-04 | | Release date: | 2016-10-05 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Inflammation-Induced Adhesin-Receptor Interaction Provides a Fitness Advantage to Uropathogenic E. coli during Chronic Infection.
Cell Host Microbe, 20, 2016
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5LNE
 | | E. coli F9 pilus adhesin FmlH bound to the Thomsen-Friedenreich (TF) antigen | | Descriptor: | NICKEL (II) ION, Putative Fml fimbrial adhesin FmlD, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose | | Authors: | Ruer, S, Conover, M.S, Kalas, V, Taganna, J, De Greve, H, Pinkner, J.S, Dodson, K.W, Hultgren, S.J, Remaut, H. | | Deposit date: | 2016-08-04 | | Release date: | 2016-10-05 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Inflammation-Induced Adhesin-Receptor Interaction Provides a Fitness Advantage to Uropathogenic E. coli during Chronic Infection.
Cell Host Microbe, 20, 2016
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2WMP
 | | Structure of the E. coli chaperone PapD in complex with the pilin domain of the PapGII adhesin | | Descriptor: | CHAPERONE PROTEIN PAPD, PAPG PROTEIN | | Authors: | Ford, B.A, Verger, D, Elam, J.S, Dodson, K.W, Pinkner, J.S, Hultgren, S.J. | | Deposit date: | 2009-07-02 | | Release date: | 2010-08-25 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the Papd-Papgii Pilin Complex Reveals an Open and Flexible P5 Pocket.
J.Bacteriol., 194, 2012
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5VQ5
 | | Crystal Structure of the Lectin Domain From the F17-like Adhesin, UclD | | Descriptor: | Adhesin, IODIDE ION | | Authors: | Klein, R.D, Spaulding, C.N, Dodson, K.W, Pinkner, J.S, Hultgren, S.J, Fremont, D. | | Deposit date: | 2017-05-08 | | Release date: | 2017-05-24 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.
Nature, 546, 2017
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3ME0
 | | Structure of the E. coli chaperone PAPD in complex with the pilin domain of the PapGII adhesin | | Descriptor: | Chaperone protein papD, PapG protein | | Authors: | Ford, B.A, Elam, J.S, Dodson, K.W, Pinkner, J.S, Hultgren, S.J. | | Deposit date: | 2010-03-31 | | Release date: | 2011-04-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structure of the E. Coli Chaperone PapD in Complex with the Pilin Domain of the PapGII Adhesin
To be Published
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5NWP
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6C53
 | | Cryo-EM structure of the Type 1 pilus rod | | Descriptor: | Type-1 fimbrial protein, A chain | | Authors: | Zheng, W, Wang, F, Luna-Rico, A, Francetic, O, Hultgren, S.J, Egelman, E.H. | | Deposit date: | 2018-01-13 | | Release date: | 2018-01-31 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions.
Elife, 7, 2018
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6CD2
 | | Crystal structure of the PapC usher bound to the chaperone-adhesin PapD-PapG | | Descriptor: | Chaperone protein PapD, Outer membrane usher protein PapC, PapGII adhesin protein | | Authors: | Omattage, N.S, Deng, Z, Yuan, P, Hultgren, S.J. | | Deposit date: | 2018-02-07 | | Release date: | 2018-10-03 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in Escherichia coli.
Nat Microbiol, 3, 2018
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5JR4
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5JQI
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7Q3N
 | | Cryo-EM of the complex between human uromodulin (UMOD)/Tamm-Horsfall protein (THP) and the FimH lectin domain from uropathogenic E. coli | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Type 1 fimbiral adhesin FimH, ... | | Authors: | Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B. | | Deposit date: | 2021-10-28 | | Release date: | 2022-03-16 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (7.4 Å) | | Cite: | Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
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1PDK
 | | PAPD-PAPK CHAPERONE-PILUS SUBUNIT COMPLEX FROM E.COLI P PILUS | | Descriptor: | PROTEIN (CHAPERONE PROTEIN PAPD), PROTEIN (PROTEIN PAPK) | | Authors: | Fuetterer, K, Sauer, F.G, Hultgren, S.J, Waksman, G. | | Deposit date: | 1999-03-29 | | Release date: | 1999-08-17 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis of chaperone function and pilus biogenesis.
Science, 285, 1999
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