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8FW2
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BU of 8fw2 by Molmil
Cryo-EM structure of full-length human NLRC4 inflammasome with C11 symmetry
Descriptor: NLR family CARD domain-containing protein 4
Authors:Matico, R.E, Yu, X, Miller, R, Somani, S, Ricketts, M.D, Kumar, N, Steele, R.A, Medley, Q, Berger, S, Faustin, B, Sharma, S.
Deposit date:2023-01-20
Release date:2024-01-03
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing.
Nat.Struct.Mol.Biol., 31, 2024
8FVU
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BU of 8fvu by Molmil
Cryo-EM structure of human Needle/NAIP/NLRC4 (R288A)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Baculoviral IAP repeat-containing protein 1, Lethal factor,Type III secretion system protein, ...
Authors:Matico, R.E, Yu, X, Miller, R, Somani, S, Ricketts, M.D, Kumar, N, Steele, R.A, Medley, Q, Berger, S, Faustin, B, Sharma, S.
Deposit date:2023-01-19
Release date:2024-01-03
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing.
Nat.Struct.Mol.Biol., 31, 2024
8FW9
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BU of 8fw9 by Molmil
Cryo-EM structure of full-length human NLRC4 inflammasome with C12 symmetry
Descriptor: NLR family CARD domain-containing protein 4
Authors:Matico, R.E, Yu, X, Miller, R, Somani, S, Ricketts, M.D, Kumar, N, Steele, R.A, Medley, Q, Berger, S, Faustin, B, Sharma, S.
Deposit date:2023-01-20
Release date:2024-01-03
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (4.46 Å)
Cite:Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing.
Nat.Struct.Mol.Biol., 31, 2024
1O78
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BU of 1o78 by Molmil
Biotin carboxyl carrier domain of transcarboxylase (1.3S) [10-48] deletion mutant
Descriptor: BIOTIN CARBOXYL CARRIER PROTEIN OF METHYLMALONYL-COA CARBOXYL-TRANSFERASE
Authors:Jank, M.M, Sadowsky, J.D, Peikert, C, Berger, S.
Deposit date:2002-10-24
Release date:2002-11-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Studies on the Solution Structure of a Deletion Mutant of the Transcarboxylase Biotin Carrier Subunit
Int.J.Biol.Macromol., 30, 2002
1EV8
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BU of 1ev8 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI
Descriptor: THYMIDYLATE SYNTHASE
Authors:Phan, J, Mahdavian, E, Nivens, M.C, Minor, W, Berger, S, Spencer, H.T, Dunlap, R.B, Lebioda, L.
Deposit date:2000-04-19
Release date:2000-05-03
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Catalytic cysteine of thymidylate synthase is activated upon substrate binding.
Biochemistry, 39, 2000
1EVF
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BU of 1evf by Molmil
CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI
Descriptor: SULFATE ION, THYMIDYLATE SYNTHASE
Authors:Phan, J, Mahdavian, E, Nivens, M.C, Minor, W, Berger, S, Spencer, H.T, Dunlap, R.B, Lebioda, L.
Deposit date:2000-04-19
Release date:2000-05-03
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Catalytic cysteine of thymidylate synthase is activated upon substrate binding.
Biochemistry, 39, 2000
1EVG
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BU of 1evg by Molmil
CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI WITH UNMODIFIED CATALYTIC CYSTEINE
Descriptor: SULFATE ION, THYMIDYLATE SYNTHASE
Authors:Phan, J, Mahdavian, E, Nivens, M.C, Minor, W, Berger, S, Spencer, H.T, Dunlap, R.B, Lebioda, L.
Deposit date:2000-04-19
Release date:2000-05-03
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Catalytic cysteine of thymidylate synthase is activated upon substrate binding.
Biochemistry, 39, 2000
1EV5
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BU of 1ev5 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF ALA167 MUTANT OF ESCHERICHIA COLI
Descriptor: SULFATE ION, THYMIDYLATE SYNTHASE
Authors:Phan, J, Mahdavian, E, Nivens, M.C, Minor, W, Berger, S, Spencer, H.T, Dunlap, R.B, Lebioda, L.
Deposit date:2000-04-19
Release date:2000-05-03
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Catalytic cysteine of thymidylate synthase is activated upon substrate binding.
Biochemistry, 39, 2000
2V3L
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BU of 2v3l by Molmil
Orientational and dynamical heterogeneity of Rhodamine 6G terminally attached to a DNA helix
Descriptor: 5'-D(*CP*AP*AP*AP*GP*CP*GP*CP*CP*AP *TP*TP*CP*GP*CP*CP*AP*TP*TP*C)-3', 5'-D(*GP*AP*AP*TP*GP*GP*CP*GP*AP*AP *TP*GP*GP*CP*GP*CP*TP*TP*TP*G)-3', RHODAMINE 6G
Authors:Neubauer, H, Gaiko, N, Berger, S, Schaffer, J, Eggeling, C, Tuma, J, Verdier, L, Seidel, C.A.M, Griesinger, C, Volkmer, A.
Deposit date:2007-06-18
Release date:2007-10-09
Last modified:2017-04-19
Method:SOLUTION NMR
Cite:Orientational and Dynamical Heterogeneity of Rhodamine 6G Terminally Attached to a DNA Helix Revealed by NMR and Single-Molecule Fluorescence Spectroscopy.
J.Am.Chem.Soc., 129, 2007
8EJA
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BU of 8eja by Molmil
Computational design of potent and selective inhibitors of Bak and Bax
Descriptor: aBAK
Authors:Bera, A.K, Berger, S.A, Baker, D.
Deposit date:2022-09-16
Release date:2024-03-20
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Computational design of potent and selective inhibitors of Bak and Bax
To Be Published
5JSN
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BU of 5jsn by Molmil
Bcl2-inhibitor complex
Descriptor: Apoptosis regulator Bcl-2, Bcl2 inhibitor
Authors:Shen, B.W, Stoddard, B.L.
Deposit date:2016-05-09
Release date:2016-11-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer.
Elife, 5, 2016
5JSB
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BU of 5jsb by Molmil
Crystal structure of Mcl1-inhibitor complex
Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1, Mcl-1 inhibitor
Authors:Shen, B.W, Stoddard, B.L.
Deposit date:2016-05-07
Release date:2016-11-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer.
Elife, 5, 2016
7YXW
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BU of 7yxw by Molmil
Structure of the p22phox A200G mutant in complex with p47phox peptide
Descriptor: Cytochrome b-245 light chain, Neutrophil cytosol factor 1
Authors:Cukier, C.D, Vuillard, L.M, Komjati, B, Szlavik, Z.
Deposit date:2022-02-16
Release date:2022-03-30
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Targeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics
Acs Med.Chem.Lett., 13, 2022
8A46
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BU of 8a46 by Molmil
Crystal structure of the human Kelch domain of Keap1 in complex with compound S217879
Descriptor: 2-[(1S,2R,8S)-2,4,32-trimethyl-28,28-bis(oxidanylidene)-19,22,27-trioxa-28$l^{6}-thia-1,14,15,16-tetrazahexacyclo[21.5.3.1^{3,7}.1^{9,13}.0^{12,16}.0^{26,30}]tritriaconta-3(33),4,6,9(32),10,12,14,23,25,30-decaen-8-yl]ethanoic acid, Kelch-like ECH-associated protein 1
Authors:Weber, C, Vuillard, L, Delerive, P, Miallau, L.
Deposit date:2022-06-10
Release date:2022-07-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.323 Å)
Cite:Selective disruption of NRF2-KEAP1 interaction leads to NASH resolution and reduction of liver fibrosis in mice.
JHEP Rep, 5, 2023
7PWD
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BU of 7pwd by Molmil
Structure of an inhibited GRK2-G-beta and G-gamma complex
Descriptor: 4-chloranyl-N-[2-(4-chlorophenyl)ethyl]thieno[2,3-c]pyridine-2-carboxamide, Beta-adrenergic receptor kinase 1, CHLORIDE ION, ...
Authors:Faucher, N, Tauchert, M.J, Konz Makino, D.L, Vuillard, L.M.
Deposit date:2021-10-06
Release date:2021-10-20
Last modified:2022-05-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Synthesis of thieno[2,3-c]pyridine derived GRK2 inhibitors
Monatsh Chem, 2022

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PDB entries from 2024-03-27

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