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1C9B
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BU of 1c9b by Molmil
CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)
Descriptor: ADMLP TATA-BOX DNA CONTAINING IIB RECOGNITION ELEMENT, GENERAL TRANSCRIPTION FACTOR IIB, TATA BOX BINDING PROTEIN
Authors:Tsai, F.T.F, Sigler, P.B.
Deposit date:1999-08-01
Release date:2000-01-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural basis of preinitiation complex assembly on human pol II promoters.
EMBO J., 19, 2000
7TFM
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BU of 7tfm by Molmil
Atomic Structure of the Leishmania spp. Hsp100 N-Domain
Descriptor: ATP-dependent Clp protease subunit, heat shock protein 100 (HSP100), GLYCEROL
Authors:Mercado, J.M, Lee, S, Chang, C, Sung, N, Soong, L, Catic, A, Tsai, F.T.F.
Deposit date:2022-01-06
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.055 Å)
Cite:Atomic structure of the Leishmania spp. Hsp100 N-domain.
Proteins, 90, 2022
8DEH
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BU of 8deh by Molmil
Ankyrin domain of SKD3
Descriptor: Caseinolytic peptidase B protein homolog
Authors:Lee, S, Tsai, F.T.F.
Deposit date:2022-06-20
Release date:2023-04-19
Method:X-RAY DIFFRACTION (1.815 Å)
Cite:Structural basis of impaired disaggregase function in the oxidation-sensitive SKD3 mutant causing 3-methylglutaconic aciduria
Nat Commun, 14, 2023
8FDS
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BU of 8fds by Molmil
Ankyrin domain of SKD3 isoform 2
Descriptor: Caseinolytic peptidase B protein homolog, FORMIC ACID
Authors:Lee, S, Tsai, F.T.F, Chang, C.
Deposit date:2022-12-04
Release date:2023-04-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis of impaired disaggregase function in the oxidation-sensitive SKD3 mutant causing 3-methylglutaconic aciduria
Nat Commun, 14, 2023
1QVR
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BU of 1qvr by Molmil
Crystal Structure Analysis of ClpB
Descriptor: ClpB protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PLATINUM (II) ION
Authors:Lee, S, Sowa, M.E, Watanabe, Y, Sigler, P.B, Chiu, W, Yoshida, M, Tsai, F.T.F.
Deposit date:2003-08-28
Release date:2003-10-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Structure of ClpB: A Molecular Chaperone that Rescues Proteins from an Aggregated State
Cell(Cambridge,Mass.), 115, 2003
6N8V
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BU of 6n8v by Molmil
Hsp104DWB open conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 104
Authors:Lee, S, Rho, S.H, Lee, J, Sung, N, Liu, J, Tsai, F.T.F.
Deposit date:2018-11-30
Release date:2019-01-02
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (9.3 Å)
Cite:Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation.
Cell Rep, 26, 2019
6N8Z
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BU of 6n8z by Molmil
HSP104DWB extended conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 104
Authors:Lee, S, Rho, S.H, Lee, J, Sung, N, Liu, J, Tsai, F.T.F.
Deposit date:2018-11-30
Release date:2019-01-02
Last modified:2019-01-16
Method:ELECTRON MICROSCOPY (9.3 Å)
Cite:Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation.
Cell Rep, 26, 2019
6N8T
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BU of 6n8t by Molmil
Hsp104DWB closed conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 104
Authors:Lee, S, Rho, S.H, Lee, J, Sung, N, Liu, J, Tsai, F.T.F.
Deposit date:2018-11-30
Release date:2019-01-02
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation.
Cell Rep, 26, 2019
3M6C
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BU of 3m6c by Molmil
Crystal structure of Mycobacterium tuberculosis GroEL1 apical domain
Descriptor: 60 kDa chaperonin 1
Authors:Tsai, F.T.F, Sielaff, B, Lee, K.
Deposit date:2010-03-15
Release date:2010-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional conservation of Mycobacterium tuberculosis GroEL paralogs suggests that GroEL1 Is a chaperonin.
J.Mol.Biol., 405, 2011
5F5R
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BU of 5f5r by Molmil
TRAP1N-ADPNP
Descriptor: Heat shock protein 75 kDa, mitochondrial, MAGNESIUM ION, ...
Authors:Tsai, F.T.F, Lee, S, Sung, N, Lee, J, Chang, C, Joachimiak, A.
Deposit date:2015-12-04
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate.
Proc.Natl.Acad.Sci.USA, 113, 2016
5HPH
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BU of 5hph by Molmil
Structure of TRAP1 fragment
Descriptor: GLYCEROL, Heat shock protein 75 kDa, mitochondrial, ...
Authors:Sung, N, Chang, C, Lee, S, Tsai, F.T.F.
Deposit date:2016-01-20
Release date:2016-08-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.429 Å)
Cite:2.4 angstrom resolution crystal structure of human TRAP1NM, the Hsp90 paralog in the mitochondrial matrix.
Acta Crystallogr D Struct Biol, 72, 2016
6NZ4
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BU of 6nz4 by Molmil
YcjX-GDP (type I)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, YcjX Stress Protein
Authors:Lee, S, Tsai, J, Tsai, F.T.
Deposit date:2019-02-12
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal Structure of the YcjX Stress Protein Reveals a Ras-Like GTP-Binding Protein.
J.Mol.Biol., 431, 2019
6NZ6
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BU of 6nz6 by Molmil
YcjX-GDP (type II)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, YcjX Stress Protein
Authors:Tsai, J, Sung, N, Lee, J, Chang, C, Lee, S, Tsai, F.T.
Deposit date:2019-02-12
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of the YcjX Stress Protein Reveals a Ras-Like GTP-Binding Protein.
J.Mol.Biol., 431, 2019
6NZ5
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BU of 6nz5 by Molmil
YcjX-GDPCP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, YcjX Stress Protein
Authors:Lee, S, Tsai, J, Tsai, F.T, Sung, N, Lee, J, Chang, C.
Deposit date:2019-02-12
Release date:2019-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.233 Å)
Cite:Crystal Structure of the YcjX Stress Protein Reveals a Ras-Like GTP-Binding Protein.
J.Mol.Biol., 431, 2019
5WBW
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BU of 5wbw by Molmil
Yeast Hsp104 fragment 1-360
Descriptor: Heat shock protein 104
Authors:Lee, S.
Deposit date:2017-06-29
Release date:2018-01-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural determinants for protein unfolding and translocation by the Hsp104 protein disaggregase.
Biosci. Rep., 37, 2017
6AMN
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BU of 6amn by Molmil
Crystal Structure of Hsp104 N Domain
Descriptor: Heat shock protein 104
Authors:Lee, S.
Deposit date:2017-08-10
Release date:2017-11-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.816 Å)
Cite:Overlapping and Specific Functions of the Hsp104 N Domain Define Its Role in Protein Disaggregation.
Sci Rep, 7, 2017
5F3K
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BU of 5f3k by Molmil
X-Ray Crystallographic Structure of hTrap1 N-terminal Domain-apo
Descriptor: Heat shock protein 75 kDa, mitochondrial
Authors:Sung, N, Lee, J, Kim, J, Chang, C, Joachimiak, A, Lee, S, Tsai, F.T.F.
Deposit date:2015-12-02
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP binding to dimer closure through a coiled-coil intermediate.
Proc.Natl.Acad.Sci.USA, 113, 2016
4FD2
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BU of 4fd2 by Molmil
Crystal structure of the C-terminal domain of ClpB
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB
Authors:Biter, A.B, Lee, S, Sung, N, Tsai, F.T.F.
Deposit date:2012-05-25
Release date:2012-07-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for intersubunit signaling in a protein disaggregating machine.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FCV
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BU of 4fcv by Molmil
Crystal structure of the C-terminal domain of ClpB
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB
Authors:Biter, A.B, Lee, S, Sung, N, Tsai, F.T.F.
Deposit date:2012-05-25
Release date:2012-07-18
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for intersubunit signaling in a protein disaggregating machine.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FCT
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BU of 4fct by Molmil
Crystal structure of the C-terminal domain of ClpB
Descriptor: Chaperone protein ClpB
Authors:Biter, A.B, Lee, S, Sung, N, Tsai, F.T.F.
Deposit date:2012-05-25
Release date:2012-07-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structural basis for intersubunit signaling in a protein disaggregating machine.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FCW
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BU of 4fcw by Molmil
Crystal structure of the C-terminal domain of ClpB
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB
Authors:Biter, A.B, Lee, S, Sung, N, Tsai, F.T.F.
Deposit date:2012-05-25
Release date:2012-07-18
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for intersubunit signaling in a protein disaggregating machine.
Proc.Natl.Acad.Sci.USA, 109, 2012

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