1B27
| |
1B3S
| |
1B2S
| |
1B2U
| |
5LAP
| p53 cancer mutant Y220C with Cys182 alkylation | Descriptor: | 5-chloranylpyrimidine-4-carboxylic acid, Cellular tumor antigen p53, ZINC ION | Authors: | Joerger, A.C, Bauer, M.R, Fersht, A.R. | Deposit date: | 2016-06-14 | Release date: | 2016-08-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | 2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
1BAN
| |
1BAO
| |
5NP0
| Closed dimer of human ATM (Ataxia telangiectasia mutated) | Descriptor: | Serine-protein kinase ATM | Authors: | Baretic, D, Pollard, H.K, Fisher, D.I, Johnson, C.M, Santhanam, B, Truman, C.M, Kouba, T, Fersht, A.R, Phillips, C, Williams, R.L. | Deposit date: | 2017-04-13 | Release date: | 2017-05-17 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (5.7 Å) | Cite: | Structures of closed and open conformations of dimeric human ATM. Sci Adv, 3, 2017
|
|
1BRS
| |
2J1Y
| |
2J1X
| |
2J1W
| |
2J20
| |
2J1Z
| |
2J21
| |
1BSE
| |
1BSA
| |
1BSD
| |
1BRG
| |
1BSB
| |
1BSC
| |
1P7I
| CRYSTAL STRUCTURE OF ENGRAILED HOMEODOMAIN MUTANT K52A | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | Deposit date: | 2003-05-02 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003
|
|
1P7J
| Crystal structure of engrailed homeodomain mutant K52E | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Segmentation polarity homeobox protein engrailed | Authors: | Stollar, E.J, Mayor, U, Lovell, S.C, Federici, L, Freund, S.M, Fersht, A.R, Luisi, B.F. | Deposit date: | 2003-05-02 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Engrailed Homeodomain Mutants: IMPLICATIONS FOR STABILITY AND DYNAMICS J.Biol.Chem., 278, 2003
|
|
1QPU
| SOLUTION STRUCTURE OF OXIDIZED ESCHERICHIA COLI CYTOCHROME B562 | Descriptor: | CYTOCHROME B562, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Arnesano, F, Banci, L, Bertini, I, Faraone-Mennella, J, Rosato, A, Barker, P.D, Fersht, A.R. | Deposit date: | 1999-05-30 | Release date: | 1999-06-02 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | The solution structure of oxidized Escherichia coli cytochrome b562. Biochemistry, 38, 1999
|
|
1CIQ
| COMPLEX OF TWO FRAGMENTS OF CI2, RESIDUES 1-40 AND 41-64 | Descriptor: | CHYMOTRYPSIN INHIBITOR 2 | Authors: | Buckle, A.M, Fersht, A.R. | Deposit date: | 1995-10-02 | Release date: | 1996-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Towards the complete structural characterization of a protein folding pathway: the structures of the denatured, transition and native states for the association/folding of two complementary fragments of cleaved chymotrypsin inhibitor 2. Direct evidence for a nucleation-condensation mechanism Structure Fold.Des., 1, 1996
|
|