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2KR6
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BU of 2kr6 by Molmil
Solution structure of presenilin-1 CTF subunit
Descriptor: Presenilin-1
Authors:Doetsch, V.
Deposit date:2009-12-04
Release date:2010-04-28
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of presenilin-1 CTF subunit
To be Published
5HKH
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BU of 5hkh by Molmil
Crystal structure of Ufm1 in complex with UBA5
Descriptor: ASP-ASN-GLU-TRP-GLY-ILE-GLU-LEU-VAL, Ubiquitin-fold modifier 1
Authors:Huber, J, Doetsch, V, Rogov, V.V, Akutsu, M.
Deposit date:2016-01-14
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation.
J.Biol.Chem., 291, 2016
1ZGW
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BU of 1zgw by Molmil
NMR structure of E. Coli Ada protein in complex with DNA
Descriptor: 5'-D(*GP*CP*AP*AP*AP*TP*TP*AP*AP*AP*GP*CP*GP*CP*AP*AP*GP*A)-3', 5'-D(*TP*CP*TP*TP*GP*CP*GP*CP*TP*TP*TP*AP*AP*TP*TP*TP*GP*C)-3', Ada polyprotein, ...
Authors:He, C, Hus, J.C, Sun, L.J, Zhou, P, Norman, D.P, Doetsch, V, Wei, H, Gross, J.D, Lane, W.S, Wagner, G, Verdine, G.L.
Deposit date:2005-04-22
Release date:2005-10-18
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:A Methylation-Dependent Electrostatic Switch Controls DNA Repair and Transcriptional Activation by E. coli Ada.
Mol.Cell, 20, 2005
1SR2
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BU of 1sr2 by Molmil
Solution structure of the Escherichia coli YojN Histidine-Phosphotransferase (HPt) domain
Descriptor: Putative sensor-like histidine kinase yojN
Authors:Rogov, V.V, Bernhard, F, Loehr, F, Doetsch, V.
Deposit date:2004-03-22
Release date:2004-10-26
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution Structure of the Escherichia coli YojN Histidine-phosphotransferase Domain and its Interaction with Cognate Phosphoryl Receiver Domains
J.Mol.Biol., 343, 2004
2GDX
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BU of 2gdx by Molmil
Solution structure of the B. brevis TycC3-PCP in H-state
Descriptor: Tyrocidine synthetase III
Authors:Koglin, A, Loehr, F, Rogov, V.V, Marahiel, M.A, Bernhard, F, Doetsch, V.
Deposit date:2006-03-17
Release date:2006-08-01
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Conformational switches modulate protein interactions in peptide antibiotic synthetases
Science, 312, 2006
2GDW
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BU of 2gdw by Molmil
Solution structure of the B. brevis TycC3-PCP in A/H-state
Descriptor: Tyrocidine synthetase III
Authors:Koglin, A, Loehr, F, Rogov, V.V, Marahiel, M.A, Bernhard, F, Doetsch, V.
Deposit date:2006-03-17
Release date:2006-08-01
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Conformational switches modulate protein interactions in peptide antibiotic synthetases
Science, 312, 2006
2GDY
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BU of 2gdy by Molmil
Solution structure of the B. brevis TycC3-PCP in A-state
Descriptor: Tyrocidine synthetase III
Authors:Koglin, A, Loehr, F, Rogov, V.V, Marahiel, M.A, Bernhard, F, Doetsch, V.
Deposit date:2006-03-17
Release date:2006-08-01
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Conformational switches modulate protein interactions in peptide antibiotic synthetases
Science, 312, 2006
2RP5
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BU of 2rp5 by Molmil
Solution structure of the oligomerization domain in CEP-1
Descriptor: Putative uncharacterized protein cep-1
Authors:Ou, H.D, Doetsch, V.
Deposit date:2008-05-01
Release date:2008-05-27
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structural evolution of C-terminal domains in the p53 family
Embo J., 26, 2007
2RP4
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BU of 2rp4 by Molmil
Solution Structure of the oligomerization domain in Dmp53
Descriptor: Transcription factor p53
Authors:Ou, H.D, Doetsch, V.
Deposit date:2008-04-30
Release date:2008-05-27
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structural evolution of C-terminal domains in the p53 family
Embo J., 26, 2007
1A66
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BU of 1a66 by Molmil
SOLUTION NMR STRUCTURE OF THE CORE NFATC1/DNA COMPLEX, 18 STRUCTURES
Descriptor: CORE NFATC1, DNA (5'-D(*CP*AP*AP*TP*TP*TP*TP*CP*CP*TP*CP*G)-3'), DNA (5'-D(*CP*GP*AP*GP*GP*AP*AP*AP*AP*TP*TP*G)-3')
Authors:Zhou, P, Sun, L.J, Doetsch, V, Wagner, G, Verdine, G.L.
Deposit date:1998-03-06
Release date:1998-06-17
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Solution structure of the core NFATC1/DNA complex.
Cell(Cambridge,Mass.), 92, 1998
4XC2
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BU of 4xc2 by Molmil
Crystal structure of GABARAP in complex with KBTBD6 LIR peptide
Descriptor: GABA(A) receptor-associated protein, Kelch repeat and BTB domain-containing protein 6
Authors:Huber, J, Genau, H.M, Baschieri, F, Doetsch, V, Farhan, H, Rogov, V.V, Behrends, C, Akutsu, M.
Deposit date:2014-12-17
Release date:2015-03-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:CUL3-KBTBD6/KBTBD7 Ubiquitin Ligase Cooperates with GABARAP Proteins to Spatially Restrict TIAM1-RAC1 Signaling.
Mol.Cell, 57, 2015
7Z7E
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BU of 7z7e by Molmil
Crystal structure of p63 DNA binding domain in complex with inhibitory DARPin G4
Descriptor: DARPIN, Isoform 4 of Tumor protein 63, ZINC ION
Authors:Strubel, A, Gebel, J, Chaikuad, A, Muenick, P, Doetsch, V.
Deposit date:2022-03-15
Release date:2022-06-29
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Cell Death Differ., 29, 2022
6H8C
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BU of 6h8c by Molmil
Structure of the human GABARAPL2 protein in complex with the UBA5 LIR motif
Descriptor: Gamma-aminobutyric acid receptor-associated protein-like 2, Ubiquitin-like modifier-activating enzyme 5
Authors:Huber, J, Loehr, F, Gruber, J, Akutsu, M, Guentert, P, Doetsch, V, Rogov, V.V.
Deposit date:2018-08-02
Release date:2019-05-01
Last modified:2020-01-29
Method:SOLUTION NMR
Cite:An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5.
Autophagy, 16, 2020
8POK
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BU of 8pok by Molmil
Cryo-EM structure of cell-free synthesized human histamine H2 receptor coupled to heterotrimeric Gs protein in lipid environment
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, HISTAMINE, ...
Authors:Schnelle, K, Koeck, Z, Persechino, M, Umbach, S, Schihada, H, Januliene, D, Parey, K, Pockes, S, Kolb, P, Doetsch, V, Moeller, A, Hilger, D, Bernhard, F.
Deposit date:2023-07-05
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of cell-free synthesized human histamine 2 receptor/G s complex in nanodisc environment.
Nat Commun, 15, 2024
8P9C
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BU of 8p9c by Molmil
Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11
Descriptor: 1,2-ETHANEDIOL, Darpin 1810 F11, Tumor protein 63, ...
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2023-06-05
Release date:2023-11-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.
Cell Death Dis, 14, 2023
8P9D
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BU of 8p9d by Molmil
Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 A2
Descriptor: Darpin 1810 A2, Tumor protein 63, Tumor protein p73
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2023-06-05
Release date:2023-11-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.
Cell Death Dis, 14, 2023
8P9E
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BU of 8p9e by Molmil
Crystal structure of wild type p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11
Descriptor: Darpin 1810 F11, GLYCEROL, Isoform 2 of Tumor protein 63, ...
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2023-06-05
Release date:2023-11-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.
Cell Death Dis, 14, 2023
4MRT
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BU of 4mrt by Molmil
Structure of the Phosphopantetheine Transferase Sfp in Complex with Coenzyme A and a Peptidyl Carrier Protein
Descriptor: 4'-phosphopantetheinyl transferase sfp, COENZYME A, GLYCEROL, ...
Authors:Tufar, P, Rahighi, S, Kraas, F.I, Kirchner, D.K, Loehr, F, Henrich, E, Koepke, J, Dikic, I, Guentert, P, Marahiel, M.A, Doetsch, V.
Deposit date:2013-09-17
Release date:2014-04-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification.
Chem.Biol., 21, 2014
1GYF
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BU of 1gyf by Molmil
GYF DOMAIN FROM HUMAN CD2BP2 PROTEIN
Descriptor: PROTEIN (CYTOPLASMIC DOMAIN BINDING PROTEIN (CD2BP2))
Authors:Freund, C, Doetsch, V, Nishizawa, K, Reinherz, E.L, Wagner, G.
Deposit date:1999-04-30
Release date:2000-01-05
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The GYF domain is a novel structural fold that is involved in lymphoid signaling through proline-rich sequences.
Nat.Struct.Biol., 6, 1999
7OVC
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BU of 7ovc by Molmil
Structure of the human UFC1 protein in complex with the UBA5 C-terminal UFC1-binding motif.
Descriptor: Ubiquitin-fold modifier-conjugating enzyme 1, Ubiquitin-like modifier-activating enzyme 5
Authors:Wesch, W, Loehr, F, Rogova, N, Doetsch, V, Rogov, V.V.
Deposit date:2021-06-14
Release date:2021-08-04
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Concerted Action of UBA5 C-Terminal Unstructured Regions Is Important for Transfer of Activated UFM1 to UFC1.
Int J Mol Sci, 22, 2021
5N2O
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BU of 5n2o by Molmil
Structure Of P63 SAM Domain L514F Mutant Causative Of AEC Syndrome
Descriptor: Tumor protein 63
Authors:Rinnenthal, J, Wuerz, J.M, Osterburg, C, Guentert, P, Doetsch, V.
Deposit date:2017-02-08
Release date:2018-02-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7Z71
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BU of 7z71 by Molmil
Crystal structure of p63 DBD in complex with darpin C14
Descriptor: Darpin C14, Isoform 4 of Tumor protein 63, ZINC ION
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-03-14
Release date:2022-07-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Cell Death Differ., 29, 2022
7Z73
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BU of 7z73 by Molmil
Crystal structure of p63 tetramerization domain in complex with darpin 8F1
Descriptor: Darpin 8F1, Isoform 2 of Tumor protein 63
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-03-14
Release date:2022-07-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Cell Death Differ., 29, 2022
7Z72
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BU of 7z72 by Molmil
Crystal structure of p63 SAM in complex with darpin A5
Descriptor: DI(HYDROXYETHYL)ETHER, Darpin A5, Isoform 9 of Tumor protein 63
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-03-14
Release date:2022-07-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Cell Death Differ., 29, 2022
2KBY
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BU of 2kby by Molmil
The Tetramerization Domain of Human p73
Descriptor: Tumor protein p73
Authors:Coutandin, D, Ikeya, T, Loehr, F, Guntert, P, Ou, H.D, Doetsch, V.
Deposit date:2008-12-12
Release date:2009-09-29
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Conformational stability and activity of p73 require a second helix in the tetramerization domain.
Cell Death Differ., 16, 2009

 

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