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3C66
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BU of 3c66 by Molmil
Yeast poly(A) polymerase in complex with Fip1 residues 80-105
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Poly(A) polymerase, ...
Authors:Bohm, A, Meinke, G.
Deposit date:2008-02-02
Release date:2008-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of yeast poly(A) polymerase in complex with a peptide from Fip1, an intrinsically disordered protein.
Biochemistry, 47, 2008
4FB3
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BU of 4fb3 by Molmil
Polyomavirus T-ag binds symmetrical repeats at the viral origin in an asymmetrical manner
Descriptor: Large T antigen, ORI DNA oligonucleotide-Crick strand, ORI DNA oligonucleotide-Watson strand
Authors:Bohm, A, Harrison, C.J, Schaffhausen, B.S, Jiang, T.
Deposit date:2012-05-22
Release date:2013-10-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.79 Å)
Cite:Polyomavirus large T antigen binds symmetrical repeats at the viral origin in an asymmetrical manner.
J.Virol., 87, 2013
3MI7
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BU of 3mi7 by Molmil
An Enhanced Repressor of Human Papillomavirus E2 Protein
Descriptor: 1,2-ETHANEDIOL, Regulatory protein E2
Authors:Bohm, A, Baleja, J, Bose, K, Meinke, G.
Deposit date:2010-04-09
Release date:2011-04-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Design and characterization of an enhanced repressor of human papillomavirus E2 protein.
Faseb J., 25, 2011
2NTC
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BU of 2ntc by Molmil
Crystal Structure of sv40 large T antigen origin binding domain with DNA
Descriptor: 21-nt PEN element of the SV40 DNA origin, large T antigen
Authors:Bohm, A, Meinke, G, Bullock, P.A.
Deposit date:2006-11-07
Release date:2007-02-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of the SV40 T-Antigen Origin Binding Domain in Complex with DNA
Plos Biol., 5, 2007
1HMC
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BU of 1hmc by Molmil
THREE-DIMENSIONAL STRUCTURE OF DIMERIC HUMAN RECOMBINANT MACROPHAGE COLONY STIMULATING FACTOR
Descriptor: HUMAN MACROPHAGE COLONY STIMULATING FACTOR
Authors:Bohm, A, Pandit, J, Jancarik, J, Halenbeck, R, Koths, K, Kim, S.-H.
Deposit date:1993-12-22
Release date:1994-04-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structure of dimeric human recombinant macrophage colony-stimulating factor.
Science, 258, 1992
2O1P
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BU of 2o1p by Molmil
Structure of yeast Poly(A) Polymerase in a somewhat closed state
Descriptor: Poly(A) polymerase
Authors:Bohm, A, Balbo, P, Toth, J.
Deposit date:2006-11-29
Release date:2007-01-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray crystallographic and steady state fluorescence characterization of the protein dynamics of yeast polyadenylate polymerase.
J.Mol.Biol., 366, 2007
2HHP
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BU of 2hhp by Molmil
Structure of yeast poly(A) polymerase in a closed conformation.
Descriptor: CITRATE ANION, MAGNESIUM ION, Poly(A) polymerase
Authors:Bohm, A, Toth, J.
Deposit date:2006-06-28
Release date:2007-01-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallographic and steady state fluorescence characterization of the protein dynamics of yeast polyadenylate polymerase.
J.Mol.Biol., 366, 2007
2Q66
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BU of 2q66 by Molmil
Structure of Yeast Poly(A) Polymerase with ATP and oligo(A)
Descriptor: 1,2-ETHANEDIOL, 5'-R(P*AP*AP*AP*AP*A)-3', ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Bohm, A, Balbo, P.
Deposit date:2007-06-04
Release date:2007-08-28
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanism of poly(A) polymerase: structure of the enzyme-MgATP-RNA ternary complex and kinetic analysis.
Structure, 15, 2007
1S26
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BU of 1s26 by Molmil
Structure of Anthrax Edema Factor-Calmodulin-alpha,beta-methyleneadenosine 5'-triphosphate Complex Reveals an Alternative Mode of ATP Binding to the Catalytic Site
Descriptor: CALCIUM ION, Calmodulin, Calmodulin-sensitive adenylate cyclase, ...
Authors:Shen, Y, Zhukovskaya, N.L, Bohm, A, Tang, W.-J.
Deposit date:2004-01-08
Release date:2004-04-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of anthrax edema factor-calmodulin-adenosine-5'-(alpha,beta-methylene)-triphosphate complex reveals an alternative mode of ATP binding to the catalytic site
Biochem.Biophys.Res.Commun., 317, 2004
1GOT
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BU of 1got by Molmil
HETEROTRIMERIC COMPLEX OF A GT-ALPHA/GI-ALPHA CHIMERA AND THE GT-BETA-GAMMA SUBUNITS
Descriptor: GT-ALPHA/GI-ALPHA CHIMERA, GT-BETA, GT-GAMMA, ...
Authors:Lambright, D.G, Sondek, J, Bohm, A, Skiba, N.P, Hamm, H.E, Sigler, P.B.
Deposit date:1996-08-07
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0 A crystal structure of a heterotrimeric G protein.
Nature, 379, 1996
5D9I
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BU of 5d9i by Molmil
SV40 Large T antigen origin binding domain bound to artificial DNA fork
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Meinke, G, Bohm, A, Bullock, P.A.
Deposit date:2015-08-18
Release date:2015-09-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based analysis of the interaction between the simian virus 40 T-antigen origin binding domain and single-stranded DNA.
J. Virol., 85, 2011
1TBG
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BU of 1tbg by Molmil
BETA-GAMMA DIMER OF THE HETEROTRIMERIC G-PROTEIN TRANSDUCIN
Descriptor: TRANSDUCIN
Authors:Sondek, J.S, Bohm, A, Lambright, D.G, Hamm, H.E, Sigler, P.B.
Deposit date:1996-06-15
Release date:1997-04-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a G-protein beta gamma dimer at 2.1A resolution.
Nature, 379, 1996
5U91
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BU of 5u91 by Molmil
Crystal structure of Tre/loxLTR complex
Descriptor: DNA (37-MER), Tre recombinase protein
Authors:Meinke, G, Karpinski, J, Buchholz, F, Bohm, A.
Deposit date:2016-12-15
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.104 Å)
Cite:Crystal structure of an engineered, HIV-specific recombinase for removal of integrated proviral DNA.
Nucleic Acids Res., 45, 2017
5UM4
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BU of 5um4 by Molmil
Crystal structure of the F255A mutant Kir3.1 cytoplasmic pore domain
Descriptor: G protein-activated inward rectifier potassium channel 1
Authors:Meinke, G, Bohm, A, Noujaim, S.
Deposit date:2017-01-26
Release date:2018-01-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the F255A mutant Kir3.1 cytoplasmic pore domain
To Be Published
1FA0
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BU of 1fa0 by Molmil
STRUCTURE OF YEAST POLY(A) POLYMERASE BOUND TO MANGANATE AND 3'-DATP
Descriptor: 3'-DEOXYADENOSINE, 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Bard, J, Zhelkovsky, A.M, Helmling, S, Moore, C.L, Bohm, A.
Deposit date:2000-07-11
Release date:2000-08-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of yeast poly(A) polymerase alone and in complex with 3'-dATP.
Science, 289, 2000
5CYN
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BU of 5cyn by Molmil
JC Virus large T-antigen origin binding domain F258L mutant
Descriptor: 1,2-ETHANEDIOL, Large T antigen
Authors:Meinke, G, Bohm, A, Bullock, P.A.
Deposit date:2015-07-30
Release date:2015-12-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Based Analyses of the JC Virus T-Antigen F258L Mutant Provides Evidence for DNA Dependent Conformational Changes in the C-Termini of Polyomavirus Origin Binding Domains.
Plos Pathog., 12, 2016
3QK2
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BU of 3qk2 by Molmil
Structure-Based Analysis of the Interaction between the Simian Virus 40 T-Antigen Origin Binding Domain and Single-Stranded DNA
Descriptor: Large T antigen, THIOCYANATE ION
Authors:Meinke, G, Bullock, P.A, Bohm, A.
Deposit date:2011-01-31
Release date:2011-02-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.643 Å)
Cite:Structure-based analysis of the interaction between the simian virus 40 T-antigen origin binding domain and single-stranded DNA.
J.Virol., 85, 2011
2TRC
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BU of 2trc by Molmil
PHOSDUCIN/TRANSDUCIN BETA-GAMMA COMPLEX
Descriptor: GADOLINIUM ATOM, PHOSDUCIN, TRANSDUCIN
Authors:Gaudet, R, Bohm, A, Sigler, P.B.
Deposit date:1997-01-06
Release date:1997-06-05
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin.
Cell(Cambridge,Mass.), 87, 1996
4LIF
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BU of 4lif by Molmil
Crystal structure of the JCV large T-antigen origin binding domain
Descriptor: Large T antigen, SULFATE ION
Authors:Meinke, G, Bohm, A, Bullock, P.
Deposit date:2013-07-02
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
Plos Pathog., 10, 2014
4LMD
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BU of 4lmd by Molmil
Crystal structure of the JCV large t-antigen origin binding domain
Descriptor: CITRATE ANION, GLYCEROL, Large T antigen
Authors:Meinke, G, Bohm, A, Bullock, P.
Deposit date:2013-07-10
Release date:2014-04-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
Plos Pathog., 10, 2014
4NBP
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BU of 4nbp by Molmil
Crystal structure of the JCV large T-antigen origin binding domain
Descriptor: L(+)-TARTARIC ACID, Large T antigen
Authors:Meinke, G, Bohm, A, Bullock, P.
Deposit date:2013-10-23
Release date:2014-03-05
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (1.315 Å)
Cite:Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
Plos Pathog., 10, 2014
2IF9
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BU of 2if9 by Molmil
Crystal Structure of SV40 T-antigen origin binding domain disulfide-linked dimer
Descriptor: Large T antigen
Authors:Meinke, G, Bullock, P.A, Bohm, A.
Deposit date:2006-09-20
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.586 Å)
Cite:The Crystal Structure of the SV40 T-Antigen Origin Binding Domain in Complex with DNA
Plos Biol., 5, 2007
3QFQ
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BU of 3qfq by Molmil
Asymmetric Assembly of Merkel Cell Polyomavirus Large T-antigen Origin Binding Domains at the Viral Origin
Descriptor: DNA (26-MER), Large T antigen
Authors:Harrison, C.J, Meinke, G, Bohm, A.
Deposit date:2011-01-22
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9001 Å)
Cite:Asymmetric assembly of merkel cell polyomavirus large T-antigen origin binding domains at the viral origin.
J.Mol.Biol., 409, 2011
3QGJ
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BU of 3qgj by Molmil
1.3A Structure of alpha-Lytic Protease Bound to Ac-AlaAlaPro-Alanal
Descriptor: 1,2-ETHANEDIOL, Ac-AlaAlaPro-Alanal peptide, Alpha-lytic protease, ...
Authors:Everill, P, Meinke, G, Bohm, A, Bachovchin, W.
Deposit date:2011-01-24
Release date:2012-02-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Substrate Binding Defines Ser195 Position in the Catalytic Triad of Serine Proteases, Not His57 protonation
To be Published
1K90
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BU of 1k90 by Molmil
Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP
Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CALMODULIN, ...
Authors:Drum, C.L, Yan, S.-Z, Bard, J, Shen, Y.-Q, Lu, D, Soelaiman, S, Grabarek, Z, Bohm, A, Tang, W.-J.
Deposit date:2001-10-26
Release date:2002-01-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
Nature, 415, 2002

 

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