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2QS4
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BU of 2qs4 by Molmil
Crystal structure of the GluR5 ligand binding core dimer in complex with LY466195 at 1.58 Angstroms resolution
Descriptor: (3S,4aR,6S,8aR)-6-{[(2S)-2-carboxy-4,4-difluoropyrrolidin-1-yl]methyl}decahydroisoquinoline-3-carboxylic acid, AMMONIUM ION, GLYCEROL, ...
Authors:Alushin, G.M, Jane, D.E, Mayer, M.L.
Deposit date:2007-07-30
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists.
Neuropharmacology, 60, 2011
2QS1
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BU of 2qs1 by Molmil
Crystal structure of the GluR5 ligand binding core dimer in complex with UBP315 at 1.80 Angstroms resolution
Descriptor: 3-({3-[(2S)-2-amino-2-carboxyethyl]-5-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)-4,5-dibromothiophene-2-carboxylic acid, CHLORIDE ION, Glutamate receptor, ...
Authors:Alushin, G.M, Jane, D.E, Mayer, M.L.
Deposit date:2007-07-30
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists.
Neuropharmacology, 60, 2011
2QS2
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BU of 2qs2 by Molmil
Crystal structure of the GluR5 ligand binding core dimer in complex with UBP318 at 1.80 Angstroms resolution
Descriptor: 3-({3-[(2S)-2-amino-2-carboxyethyl]-5-bromo-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)thiophene-2-carboxylic acid, CHLORIDE ION, Glutamate receptor, ...
Authors:Alushin, G.M, Jane, D.E, Mayer, M.L.
Deposit date:2007-07-30
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists.
Neuropharmacology, 60, 2011
3IZ0
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BU of 3iz0 by Molmil
Human Ndc80 Bonsai Decorated Microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Alushin, G.M, Ramey, V.H, Pasqualato, S, Ball, D.A, Grigorieff, N, Musacchio, A, Nogales, E.
Deposit date:2010-08-09
Release date:2010-10-13
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8.6 Å)
Cite:The Ndc80 kinetochore complex forms oligomeric arrays along microtubules.
Nature, 467, 2010
3J6E
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BU of 3j6e by Molmil
Energy minimized average structure of Microtubules stabilized by GmpCpp
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E.
Deposit date:2014-02-18
Release date:2014-06-04
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
3J6F
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BU of 3j6f by Molmil
Minimized average structure of GDP-bound dynamic microtubules
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E.
Deposit date:2014-02-19
Release date:2014-06-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
3J6G
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BU of 3j6g by Molmil
Minimized average structure of microtubules stabilized by taxol
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E.
Deposit date:2014-02-19
Release date:2014-06-04
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
2QS3
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BU of 2qs3 by Molmil
Crystal structure of the GluR5 ligand binding core dimer in complex with UBP316 at 1.76 Angstroms resolution
Descriptor: 3-({3-[(2S)-2-amino-2-carboxyethyl]-5-methyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)-5-phenylthiophene-2-carboxylic acid, CHLORIDE ION, Glutamate receptor, ...
Authors:Alushin, G.M, Jane, D.E, Mayer, M.L.
Deposit date:2007-07-30
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:ACET is a highly potent and specific kainate receptor antagonist: characterisation and effects on hippocampal mossy fibre function.
Neuropharmacology, 56, 2009
7R91
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BU of 7r91 by Molmil
cryo-EM structure of the rigor state wild type myosin-15-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Gong, R, Reynolds, M.J, Gurel, P, Alushin, G.M.
Deposit date:2021-06-28
Release date:2021-07-28
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
7R8V
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BU of 7r8v by Molmil
Cryo-EM structure of the ADP state actin filament
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Gong, R, Espinosa de los Reyes, S, Reynolds, M.J, Gurel, P, Alushin, G.M.
Deposit date:2021-06-27
Release date:2021-07-28
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
6E7C
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BU of 6e7c by Molmil
14-pf 3-start GMPCPP-human alpha1B/beta2B microtubules
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Ti, S.C, Alushin, G.M, Kapoor, T.M.
Deposit date:2018-07-25
Release date:2018-10-10
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Human beta-Tubulin Isotypes Can Regulate Microtubule Protofilament Number and Stability.
Dev. Cell, 47, 2018
6E7B
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BU of 6e7b by Molmil
13-pf 3-start GMPCPP-human alpha1B/beta3 microtubules
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
Authors:Ti, S.C, Alushin, G.M, Kapoor, T.M.
Deposit date:2018-07-25
Release date:2018-10-10
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Human beta-Tubulin Isotypes Can Regulate Microtubule Protofilament Number and Stability.
Dev. Cell, 47, 2018
8D16
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BU of 8d16 by Molmil
Bent ADP-Pi-F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Reynolds, M.J, Alushin, G.M.
Deposit date:2022-05-26
Release date:2022-09-07
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
8D13
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BU of 8d13 by Molmil
Helical ADP-F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Reynolds, M.J, Alushin, G.M.
Deposit date:2022-05-26
Release date:2022-09-07
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (2.43 Å)
Cite:Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
8D18
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BU of 8d18 by Molmil
Straight ADP-F-actin 2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Reynolds, M.J, Alushin, G.M.
Deposit date:2022-05-26
Release date:2022-09-07
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
8D17
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BU of 8d17 by Molmil
Straight ADP-F-actin 1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Reynolds, M.J, Alushin, G.M.
Deposit date:2022-05-26
Release date:2022-09-07
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
8D14
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BU of 8d14 by Molmil
Helical ADP-Pi-F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Reynolds, M.J, Alushin, G.M.
Deposit date:2022-05-26
Release date:2022-09-07
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
8D15
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BU of 8d15 by Molmil
Bent ADP-F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Reynolds, M.J, Alushin, G.M.
Deposit date:2022-05-26
Release date:2022-09-07
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
6BNW
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BU of 6bnw by Molmil
CryoEM structure of Myosin VI-Actin complex in the ADP state, backbone-averaged with side chains truncated to alanine
Descriptor: Actin, alpha skeletal muscle, Unconventional myosin-VI
Authors:Gurel, P.G, Alushin, G.M.
Deposit date:2017-11-17
Release date:2018-01-10
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity.
Elife, 6, 2017
6BNQ
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BU of 6bnq by Molmil
CryoEM structure of Myosin VI-Actin complex in the ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Gurel, P.G, Alushin, G.M.
Deposit date:2017-11-17
Release date:2018-01-10
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity.
Elife, 6, 2017
6UPV
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BU of 6upv by Molmil
Alpha-E-catenin ABD-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mei, L, Alushin, G.M.
Deposit date:2019-10-18
Release date:2020-09-30
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular mechanism for direct actin force-sensing by alpha-catenin.
Elife, 9, 2020
6UPW
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BU of 6upw by Molmil
Metavinculin ABD-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mei, L, Alushin, G.M.
Deposit date:2019-10-18
Release date:2020-09-30
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular mechanism for direct actin force-sensing by alpha-catenin.
Elife, 9, 2020
7RB8
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BU of 7rb8 by Molmil
cryo-EM structure of the ADP state wild type myosin-15-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Gong, R, Reynolds, M.J, Gurel, P, Alushin, G.M.
Deposit date:2021-07-05
Release date:2021-07-28
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
7RB9
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BU of 7rb9 by Molmil
Cryo-EM structure of the rigor state Jordan myosin-15-F-actin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Gong, R, Reynolds, M.J, Gurel, P, Alushin, G.M.
Deposit date:2021-07-05
Release date:2021-07-28
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (3.76 Å)
Cite:Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
7SXA
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BU of 7sxa by Molmil
T-Plastin-F-actin complex, pre-bundling intermediate state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mei, L, Reynolds, M.J, Alushin, G.M.
Deposit date:2021-11-22
Release date:2022-08-31
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (6.87 Å)
Cite:Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022

 

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PDB entries from 2024-03-27

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