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1YNN
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BU of 1ynn by Molmil
Taq RNA polymerase-rifampicin complex
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A.
Deposit date:2005-01-24
Release date:2005-03-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
Embo J., 24, 2005
1YNJ
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BU of 1ynj by Molmil
Taq RNA polymerase-Sorangicin complex
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A.
Deposit date:2005-01-24
Release date:2005-03-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
Embo J., 24, 2005
2Q1Z
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BU of 2q1z by Molmil
Crystal Structure of Rhodobacter sphaeroides SigE in complex with the anti-sigma ChrR
Descriptor: Anti-Sigma factor ChrR, transcriptional activator ChrR, RpoE, ...
Authors:Campbell, E.A, Darst, S.A.
Deposit date:2007-05-25
Release date:2007-09-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria.
Mol.Cell, 27, 2007
1I6V
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BU of 1i6v by Molmil
THERMUS AQUATICUS CORE RNA POLYMERASE-RIFAMPICIN COMPLEX
Descriptor: DNA-DIRECTED RNA POLYMERASE, MAGNESIUM ION, RIFAMPICIN, ...
Authors:Campbell, E.A, Korzheva, N, Mustaev, A, Murakami, K, Goldfarb, A, Darst, S.A.
Deposit date:2001-03-05
Release date:2001-04-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural mechanism for rifampicin inhibition of bacterial rna polymerase.
Cell(Cambridge,Mass.), 104, 2001
1OR7
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BU of 1or7 by Molmil
Crystal Structure of Escherichia coli sigmaE with the Cytoplasmic Domain of its Anti-sigma RseA
Descriptor: RNA polymerase sigma-E factor, Sigma-E factor negative regulatory protein
Authors:Campbell, E.A, Tupy, J.L, Gruber, T.M, Wang, S, Sharp, M.M, Gross, C.A, Darst, S.A.
Deposit date:2003-03-12
Release date:2003-04-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA.
Mol.Cell, 11, 2003
1KU2
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BU of 1ku2 by Molmil
Crystal Structure of Thermus aquaticus RNA Polymerase Sigma Subunit Fragment Containing Regions 1.2 to 3.1
Descriptor: SULFATE ION, sigma factor sigA
Authors:Campbell, E.A, Muzzin, O, Chlenov, M, Sun, J.L, Olson, C.A, Weinman, O, Trester-Zedlitz, M.L, Darst, S.A.
Deposit date:2002-01-21
Release date:2002-04-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
1KU7
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BU of 1ku7 by Molmil
Crystal Structure of Thermus aquatics RNA Polymerase SigmaA Subunit Region 4 Bound to-35 Element DNA
Descriptor: 5'-D(*CP*CP*TP*TP*GP*AP*CP*AP*AP*AP*G)-3', 5'-D(*CP*CP*TP*TP*TP*GP*TP*CP*AP*AP*G)-3', sigma factor sigA
Authors:Campbell, E.A, Muzzin, O, Chlenov, M, Sun, J.L, Olson, C.A, Weinman, O, Trester-Zedlitz, M.L, Darst, S.A.
Deposit date:2002-01-21
Release date:2002-03-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
1KU3
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BU of 1ku3 by Molmil
Crystal Structure of Thermus aquaticus RNA Polymerase Sigma Subunit Fragment, Region 4
Descriptor: sigma factor sigA
Authors:Campbell, E.A, Muzzin, O, Chlenov, M, Sun, J.L, Olson, C.A, Weinman, O, Trester-Zedlitz, M.L, Darst, S.A.
Deposit date:2002-01-21
Release date:2002-04-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
1L0O
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BU of 1l0o by Molmil
Crystal Structure of the Bacillus stearothermophilus Anti-Sigma Factor SpoIIAB with the Sporulation Sigma Factor SigmaF
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, MAGNESIUM ION, ...
Authors:Campbell, E.A, Masuda, S, Sun, J.L, Muzzin, O, Olson, C.A, Wang, S, Darst, S.A.
Deposit date:2002-02-12
Release date:2002-04-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the Bacillus stearothermophilus anti-sigma factor SpoIIAB with the sporulation sigma factor sigmaF.
Cell(Cambridge,Mass.), 108, 2002
2Z2S
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BU of 2z2s by Molmil
Crystal Structure of Rhodobacter sphaeroides SigE in complex with the anti-sigma ChrR
Descriptor: Anti-Sigma factor ChrR, transcriptional activator ChrR, RpoE, ...
Authors:Darst, S.A, Campbell, E.A.
Deposit date:2007-05-26
Release date:2008-02-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A conserved structural module regulates transcriptional responses to diverse stress signals in bacteria.
Mol.Cell, 27, 2007
5UI5
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BU of 5ui5 by Molmil
Crystal structure of Aquifex aeolicus sigmaN bound to promoter DNA
Descriptor: DNA (30-MER), DNA (31-MER), RNA polymerase sigma factor RpoN
Authors:Darst, S.A, Campbell, E.A, Rajashankar, K.
Deposit date:2017-01-12
Release date:2017-02-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of Aquifex aeolicus sigma (N) bound to promoter DNA and the structure of sigma (N)-holoenzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UI8
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BU of 5ui8 by Molmil
structure of sigmaN-holoenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Darst, S.A, Campbell, E.A.
Deposit date:2017-01-13
Release date:2017-02-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.76 Å)
Cite:Crystal structure of Aquifex aeolicus sigma (N) bound to promoter DNA and the structure of sigma (N)-holoenzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4X8K
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BU of 4x8k by Molmil
Mycobacterium tuberculosis RbpA-SID in complex with SigmaA domain 2
Descriptor: 1,2-ETHANEDIOL, RNA polymerase sigma factor SigA, RNA polymerase-binding protein RbpA, ...
Authors:Hubin, E.A, Flack, J.E, Tabib-Salazar, A, Paget, M.S, Darst, S.A, Campbell, E.A.
Deposit date:2014-12-10
Release date:2015-06-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Structural, functional, and genetic analyses of the actinobacterial transcription factor RbpA.
Proc.Natl.Acad.Sci.USA, 112, 2015
6XEZ
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BU of 6xez by Molmil
Structure of SARS-CoV-2 replication-transcription complex bound to nsp13 helicase - nsp13(2)-RTC
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ...
Authors:Chen, J, Malone, B, Llewellyn, E.C, Campbell, E.A, Darst, S.A.
Deposit date:2020-06-14
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex.
Cell, 182, 2020
8SQ9
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BU of 8sq9 by Molmil
SARS-CoV-2 replication-transcription complex bound to nsp9 and UMPCPP, as a pre-catalytic NMPylation intermediate
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]uridine, MAGNESIUM ION, Non-structural protein 7, ...
Authors:Small, G.I, Darst, S.A, Campbell, E.A.
Deposit date:2023-05-04
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain.
Mol.Cell, 83, 2023
8SQK
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BU of 8sqk by Molmil
SARS-CoV-2 replication-transcription complex bound to RNA-nsp9 and GDP-betaS, as a pre-catalytic deRNAylation/mRNA capping intermediate
Descriptor: 5'-O-[(R)-hydroxy(thiophosphonooxy)phosphoryl]guanosine, MAGNESIUM ION, Non-structural protein 7, ...
Authors:Small, G.I, Darst, S.A, Campbell, E.A.
Deposit date:2023-05-04
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain.
Mol.Cell, 83, 2023
8SQJ
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BU of 8sqj by Molmil
SARS-CoV-2 replication-transcription complex bound to RNA-nsp9, as a noncatalytic RNA-nsp9 binding mode
Descriptor: 5'-O-[(R)-hydroxy(thiophosphonooxy)phosphoryl]guanosine, MAGNESIUM ION, Non-structural protein 7, ...
Authors:Small, G.I, Darst, S.A, Campbell, E.A.
Deposit date:2023-05-04
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain.
Mol.Cell, 83, 2023
6C06
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BU of 6c06 by Molmil
Mycobacterium tuberculosis RNAP Holo/RbpA/Fidaxomicin
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M.
Deposit date:2017-12-27
Release date:2018-03-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (5.15 Å)
Cite:Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
8DY7
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BU of 8dy7 by Molmil
Streptomyces venezuelae RNAP transcription open promoter complex with WhiA and WhiB transcription factors
Descriptor: DNA (71-MER), DNA (78-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Lilic, M, Campbell, E.A.
Deposit date:2022-08-03
Release date:2023-03-01
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DY9
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BU of 8dy9 by Molmil
Streptomyces venezuelae RNAP unconstrained open promoter complex with WhiA and WhiB transcription factors
Descriptor: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lilic, M, Campbell, E.A.
Deposit date:2022-08-03
Release date:2023-03-01
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
Proc.Natl.Acad.Sci.USA, 120, 2023
6C05
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BU of 6c05 by Molmil
Mycobacterium tuberculosis RNAP Holo/RbpA in relaxed state
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M.
Deposit date:2017-12-27
Release date:2018-03-28
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (5.15 Å)
Cite:Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
6C04
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BU of 6c04 by Molmil
Mtb RNAP Holo/RbpA/double fork DNA -closed clamp
Descriptor: DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M.
Deposit date:2017-12-27
Release date:2018-03-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
8E8M
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BU of 8e8m by Molmil
Mycobacterium tuberculosis RNAP paused elongation complex
Descriptor: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Delbeau, M, Darst, S.A, Campbell, E.A.
Deposit date:2022-08-25
Release date:2023-03-22
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
8E82
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BU of 8e82 by Molmil
Mycobacterium tuberculosis RNAP elongation complex with NusG transcription factor
Descriptor: DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Delbeau, M, Darst, S.A, Campbell, E.A.
Deposit date:2022-08-25
Release date:2023-03-22
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023
8E95
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BU of 8e95 by Molmil
Mycobacterium tuberculosis RNAP elongation complex
Descriptor: DNA (25-MER), DNA (33-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Delbeau, M, Darst, S.A, Campbell, E.A.
Deposit date:2022-08-26
Release date:2023-03-22
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural and functional basis of the universal transcription factor NusG pro-pausing activity in Mycobacterium tuberculosis.
Mol.Cell, 83, 2023

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PDB entries from 2024-03-27

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