Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6WAR
DownloadVisualize
BU of 6war by Molmil
Crystal structure of the MERS-CoV RBD bound by the neutralizing single-domain antibody MERS VHH-55
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein, nanobody MERS VHH-55
Authors:Wrapp, D, Torres, G.M, McLellan, J.S.
Deposit date:2020-03-25
Release date:2020-04-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
Cell, 181, 2020
6WAQ
DownloadVisualize
BU of 6waq by Molmil
Crystal structure of the SARS-CoV-1 RBD bound by the cross-reactive single-domain antibody SARS VHH-72
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, nanobody SARS VHH-72
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2020-03-25
Release date:2020-04-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
Cell, 181, 2020
6VSB
DownloadVisualize
BU of 6vsb by Molmil
Prefusion 2019-nCoV spike glycoprotein with a single receptor-binding domain up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Wrapp, D, Wang, N, Corbett, K.S, Goldsmith, J.A, Hsieh, C, Abiona, O, Graham, B.S, McLellan, J.S.
Deposit date:2020-02-10
Release date:2020-02-26
Last modified:2021-01-27
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.
Science, 367, 2020
6U7K
DownloadVisualize
BU of 6u7k by Molmil
Prefusion structure of PEDV spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2019-09-03
Release date:2019-09-18
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:The 3.1-Angstrom Cryo-electron Microscopy Structure of the Porcine Epidemic Diarrhea Virus Spike Protein in the Prefusion Conformation.
J.Virol., 93, 2019
8EU8
DownloadVisualize
BU of 8eu8 by Molmil
Cryo-EM structure of CH848 10.17DT DS-SOSIP-2P Env
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848 10.17DT SOSIP Envelope glycoprotein gp160
Authors:Wrapp, D, Acharya, P, Haynes, B.F.
Deposit date:2022-10-18
Release date:2023-01-04
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Structure-Based Stabilization of SOSIP Env Enhances Recombinant Ectodomain Durability and Yield.
J.Virol., 97, 2023
7KBB
DownloadVisualize
BU of 7kbb by Molmil
Cryo-EM structure of the HCMV pentamer bound by Fabs 2-18 and 8I21
Descriptor: 2-18 Fab Heavy Chain, 2-18 Fab Light Chain, 8I21 Fab Heavy Chain, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2020-10-01
Release date:2021-08-11
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7KBA
DownloadVisualize
BU of 7kba by Molmil
Crystal structure of the HCMV pentamer-specific Fab 2-18
Descriptor: 2-18 Fab Heavy Chain, 2-18 Fab Light Chain
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2020-10-01
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7M1C
DownloadVisualize
BU of 7m1c by Molmil
Crystal structure of the HCMV pentamer-specific antibody 1-32
Descriptor: 1-32 Fab Heavy Chain, 1-32 Fab Light Chain
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2021-03-12
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7M30
DownloadVisualize
BU of 7m30 by Molmil
Cryo-EM structure of the HCMV pentamer bound by antibodies 1-103, 1-32 and 2-25
Descriptor: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain, 1-32 Fab Heavy Chain, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2021-03-17
Release date:2021-08-11
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7LYV
DownloadVisualize
BU of 7lyv by Molmil
Crystal structure of the HCMV pentamer-specific antibody 1-103
Descriptor: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain
Authors:Wrapp, D, Jones, H.G, McLellan, J.S.
Deposit date:2021-03-08
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7M22
DownloadVisualize
BU of 7m22 by Molmil
Cryo-EM structure of the HCMV pentamer bound by human neuropilin 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein UL130, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2021-03-15
Release date:2021-08-11
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7LYW
DownloadVisualize
BU of 7lyw by Molmil
Crystal structure of the HCMV pentamer-specific antibody 2-25
Descriptor: 2-25 Fab Heavy Chain, 2-25 Fab Light Chain
Authors:Wrapp, D, Mishra, A.K, McLellan, J.S.
Deposit date:2021-03-08
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
6XKL
DownloadVisualize
BU of 6xkl by Molmil
SARS-CoV-2 HexaPro S One RBD up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Wrapp, D, Hsieh, C.-L, Goldsmith, J.A, McLellan, J.S.
Deposit date:2020-06-26
Release date:2020-07-15
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structure-based design of prefusion-stabilized SARS-CoV-2 spikes.
Science, 369, 2020
6UOE
DownloadVisualize
BU of 6uoe by Molmil
3-25 Fab germline-reversion variant bound to an HCMV gB-derived peptide
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-25 Fab heavy chain, 3-25 Fab light chain, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2019-10-14
Release date:2020-07-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step.
Plos Pathog., 16, 2020
8DF1
DownloadVisualize
BU of 8df1 by Molmil
Chi3l1 bound by antibody C59
Descriptor: C59 Fab Heavy chain, C59 Fab Light chain, Chitinase-3-like protein 1, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2022-06-21
Release date:2023-03-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.
Antib Ther, 6, 2023
6APD
DownloadVisualize
BU of 6apd by Molmil
Crystal structure of RSV F bound by AM22 and the infant antibody ADI-19425
Descriptor: AM22 Fab Heavy Chain,IGH@ protein, AM22 Fab Light Chain,Uncharacterized protein, Fusion glycoprotein F0,Envelope glycoprotein, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2017-08-17
Release date:2018-03-21
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation.
Immunity, 48, 2018
7LUC
DownloadVisualize
BU of 7luc by Molmil
Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B
Descriptor: 01.4B Fab Heavy chain, 01.4B Fab Light chain, 32.4K Fab Heavy chain, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2021-02-22
Release date:2021-04-21
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses.
Immunity, 54, 2021
5TP3
DownloadVisualize
BU of 5tp3 by Molmil
Crystal structure of the RSV-neutralizing single-domain antibody F-VHH-4
Descriptor: F-VHH-4
Authors:Wrapp, D, Gilman, M.S.A, McLellan, J.S.
Deposit date:2016-10-19
Release date:2017-02-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.874 Å)
Cite:Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nat Commun, 8, 2017
8F5H
DownloadVisualize
BU of 8f5h by Molmil
SARS-CoV-2 S2 helix epitope scaffold
Descriptor: S2hlx_EX_19
Authors:Kapingidza, A.B, Wrapp, D, Winters, K, Azoitei, M.L.
Deposit date:2022-11-14
Release date:2023-10-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.
Nat Commun, 14, 2023
8F5I
DownloadVisualize
BU of 8f5i by Molmil
SARS-CoV-2 S2 helix epitope scaffold bound by antibody DH1057.1
Descriptor: DH1057.1 HC, DH1057.1 LC, Specialized acyl carrier protein, ...
Authors:Kapingidza, A.B, Wrapp, D, Winters, K, Azoitei, M.L.
Deposit date:2022-11-14
Release date:2023-10-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.
Nat Commun, 14, 2023
8FDO
DownloadVisualize
BU of 8fdo by Molmil
SARS-CoV-2 fusion peptide epitope scaffold FP15 bound to DH1058
Descriptor: DH1058 Heavy chain, DH1058 Light chain, FP15
Authors:Kapingidza, A.B, Marston, D.J, Wrapp, D, Winters, K, Azoitei, M.L.
Deposit date:2022-12-04
Release date:2023-10-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.
Nat Commun, 14, 2023
7KHA
DownloadVisualize
BU of 7kha by Molmil
Cryo-EM Structure of the Desulfovibrio vulgaris Type I-C Apo Cascade
Descriptor: CRISPR-associated protein, CT1133 family, CT1134 family, ...
Authors:O'Brien, R, Wrapp, D, Bravo, J.P.K, Schwartz, E, Taylor, D.
Deposit date:2020-10-20
Release date:2020-11-11
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural basis for assembly of non-canonical small subunits into type I-C Cascade.
Nat Commun, 11, 2020
5VZR
DownloadVisualize
BU of 5vzr by Molmil
Crystal Structure of MERS-CoV neutralizing antibody G4 Fab
Descriptor: G4 antibody heavy chain, G4 antibody light chain, GLYCEROL
Authors:Wang, N, Wrapp, D, McLellan, J.S.
Deposit date:2017-05-29
Release date:2017-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VYH
DownloadVisualize
BU of 5vyh by Molmil
Crystal Structure of MERS-CoV S1 N-terminal Domain
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
Authors:Wang, N, Wrapp, D, Pallesen, J, Ward, A.B, McLellan, J.S.
Deposit date:2017-05-25
Release date:2017-08-30
Last modified:2021-03-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6ZP7
DownloadVisualize
BU of 6zp7 by Molmil
SARS-CoV-2 spike in prefusion state (flexibility analysis, 1-up open conformation)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ...
Authors:Martinez, M, Marabini, R, Carazo, J.M.
Deposit date:2020-07-08
Release date:2020-07-29
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Continuous flexibility analysis of SARS-CoV-2 spike prefusion structures.
Iucrj, 7, 2020

 

123>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon