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1MWL
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BU of 1mwl by Molmil
Crystal structure of geneticin bound to the eubacterial 16S rRNA A site
Descriptor: 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', GENETICIN
Authors:Vicens, Q, Westhof, E.
Deposit date:2002-09-30
Release date:2003-02-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide
J.Mol.Biol., 326, 2003
1LC4
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BU of 1lc4 by Molmil
Crystal Structure of Tobramycin Bound to the Eubacterial 16S rRNA A Site
Descriptor: 5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', TOBRAMYCIN
Authors:Vicens, Q, Westhof, E.
Deposit date:2002-04-05
Release date:2003-04-08
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Crystal Structure of a Complex between the Aminoglycoside Tobramycin and an Oligonucleotide Containing the Ribosomal Decoding A Site
Chem.Biol., 9, 2002
2YIF
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BU of 2yif by Molmil
Crystal structure of a F. nucleatum FMN riboswitch - Free state
Descriptor: FMN RIBOSWITCH, MAGNESIUM ION, POTASSIUM ION
Authors:Vicens, Q, Mondragon, E, Batey, R.T.
Deposit date:2011-05-12
Release date:2011-08-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.298 Å)
Cite:Molecular Sensing by the Aptamer Domain of the Fmn Riboswitch: A General Model for Ligand Binding by Conformational Selection.
Nucleic Acids Res., 39, 2011
2YIE
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BU of 2yie by Molmil
Crystal structure of a F. nucleatum FMN riboswitch bound to FMN
Descriptor: FLAVIN MONONUCLEOTIDE, FMN RIBOSWITCH, MAGNESIUM ION, ...
Authors:Vicens, Q, Mondragon, E, Batey, R.T.
Deposit date:2011-05-12
Release date:2011-08-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.941 Å)
Cite:Molecular Sensing by the Aptamer Domain of the Fmn Riboswitch: A General Model for Ligand Binding by Conformational Selection
Nucleic Acids Res., 39, 2011
1J7T
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BU of 1j7t by Molmil
Complex between Paromomycin and the 16S-rRNA A-site at 2.5 A resolution
Descriptor: 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', PAROMOMYCIN
Authors:Vicens, Q, Westhof, E.
Deposit date:2001-05-18
Release date:2002-05-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site.
Structure, 9, 2001
6DN2
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BU of 6dn2 by Molmil
CRYSTAL STRUCTURE OF THE FMN RIBOSWITCH BOUND TO BRX1354 SPLIT RNA
Descriptor: 4-{benzyl[2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethyl]amino}butanoic acid, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Vicens, Q, Mondragon, E, Reyes, F.E, Berman, J, Kaur, H, Kells, K, Wickens, P, Wilson, J, Gadwood, R, Schostarez, H, Suto, R.K, Coish, P, Blount, K.F, Batey, R.T.
Deposit date:2018-06-05
Release date:2018-09-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Structure-Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch.
ACS Chem. Biol., 13, 2018
6DN3
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BU of 6dn3 by Molmil
CRYSTAL STRUCTURE OF THE FMN RIBOSWITCH BOUND TO BRX1555 SPLIT RNA
Descriptor: 7,8-dimethyl-2,4-dioxo-10-(3-phenylpropyl)-1,2,3,4-tetrahydrobenzo[g]pteridin-10-ium, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Vicens, Q, Mondragon, E, Reyes, F.E, Berman, J, Kaur, H, Kells, K, Wickens, P, Wilson, J, Gadwood, R, Schostarez, H, Suto, R.K, Coish, P, Blount, K.F, Batey, R.T.
Deposit date:2018-06-05
Release date:2018-09-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch.
ACS Chem. Biol., 13, 2018
6DN1
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CRYSTAL STRUCTURE OF THE FMN RIBOSWITCH BOUND TO BRX1151 SPLIT RNA
Descriptor: 10-(6-carboxyhexyl)-8-(cyclopentylamino)-2,4-dihydroxy-7-methylbenzo[g]pteridin-10-ium, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Vicens, Q, Mondragon, E, Reyes, F.E, Berman, J, Kaur, H, Kells, K, Wickens, P, Wilson, J, Gadwood, R, Schostarez, H, Suto, R.K, Coish, P, Blount, K.F, Batey, R.T.
Deposit date:2018-06-05
Release date:2018-09-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Structure-Activity Relationship of Flavin Analogues That Target the Flavin Mononucleotide Riboswitch.
ACS Chem. Biol., 13, 2018
5OSG
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BU of 5osg by Molmil
Structure of KSRP in context of Leishmania donovani 80S
Descriptor: 18S rRNA, 40S ribosomal protein S6, RNA binding protein, ...
Authors:Brito Querido, J, Mancera-Martinez, E, Vicens, Q, Bochler, A, Chicher, J, Simonetti, A, Hashem, Y.
Deposit date:2017-08-17
Release date:2017-11-15
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The cryo-EM Structure of a Novel 40S Kinetoplastid-Specific Ribosomal Protein.
Structure, 25, 2017
5OPT
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BU of 5opt by Molmil
Structure of KSRP in context of Trypanosoma cruzi 40S
Descriptor: 18S rRNA, 40S ribosomal protein S10, putative, ...
Authors:Brito Querido, J, Mancera-Martinez, E, Vicens, Q, Bochler, A, Chicher, J, Simonetti, A, Hashem, Y.
Deposit date:2017-08-10
Release date:2017-11-15
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The cryo-EM Structure of a Novel 40S Kinetoplastid-Specific Ribosomal Protein.
Structure, 25, 2017
8GBD
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BU of 8gbd by Molmil
Homo sapiens Zalpha mutant - P193A
Descriptor: Double-stranded RNA-specific adenosine deaminase
Authors:Langeberg, C.J, Vogeli, B, Nichols, P.J, Henen, M, Vicens, Q.
Deposit date:2023-02-25
Release date:2023-03-22
Last modified:2023-03-29
Method:SOLUTION NMR
Cite:Differential Structural Features of Two Mutant ADAR1p150 Z alpha Domains Associated with Aicardi-Goutieres Syndrome.
J.Mol.Biol., 435, 2023
8GBC
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BU of 8gbc by Molmil
Homo sapiens Zalpha mutant - N173S
Descriptor: Double-stranded RNA-specific adenosine deaminase
Authors:Langeberg, C.J, Nichols, P.J, Henen, M, Vicens, Q, Vogeli, B.
Deposit date:2023-02-25
Release date:2023-03-22
Last modified:2023-03-29
Method:SOLUTION NMR
Cite:Differential Structural Features of Two Mutant ADAR1p150 Z alpha Domains Associated with Aicardi-Goutieres Syndrome.
J.Mol.Biol., 435, 2023
7A01
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BU of 7a01 by Molmil
The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism
Descriptor: 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES21, ...
Authors:Abaeva, I, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T.V, Hashem, Y, Hellen, C.U.T.
Deposit date:2020-08-05
Release date:2020-12-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Cell Rep, 33, 2020
6ZVK
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BU of 6zvk by Molmil
The Halastavi arva virus (HalV) intergenic region IRES promotes translation by the simplest possible initiation mechanism
Descriptor: 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES17, ...
Authors:Abaeva, I.S, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T, Hashem, Y, Hellen, C.U.T.
Deposit date:2020-07-24
Release date:2020-12-23
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Cell Rep, 33, 2020
5LI0
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BU of 5li0 by Molmil
70S ribosome from Staphylococcus aureus
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Khusainov, I, Vicens, Q, Bochler, A, Grosse, F, Myasnikov, A, Menetret, J.F, Chicher, J, Marzi, S, Romby, P, Yusupova, G, Yusupov, M, Hashem, Y.
Deposit date:2016-07-13
Release date:2016-12-28
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the 70S ribosome from human pathogen Staphylococcus aureus.
Nucleic Acids Res., 44, 2016
5ND9
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BU of 5nd9 by Molmil
Hibernating ribosome from Staphylococcus aureus (Rotated state)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Khusainov, I, Vicens, Q, Ayupov, R, Usachev, K, Myasnikov, A, Simonetti, A, Validov, S, Kieffer, B, Yusupova, G, Yusupov, M, Hashem, Y.
Deposit date:2017-03-07
Release date:2017-06-28
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF.
EMBO J., 36, 2017
5ND8
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BU of 5nd8 by Molmil
Hibernating ribosome from Staphylococcus aureus (Unrotated state)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Khusainov, I, Vicens, Q, Ayupov, R, Usachev, K, Myasnikov, A, Simonetti, A, Validov, S, Kieffer, B, Yusupova, G, Yusupov, M, Hashem, Y.
Deposit date:2017-03-07
Release date:2017-06-28
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF.
EMBO J., 36, 2017
7UVT
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BU of 7uvt by Molmil
Kinetically trapped misfolded state of the Tetrahymena ribozyme
Descriptor: RNA (386-MER)
Authors:Bonilla, S.L, Vicens, Q, Kieft, J.S.
Deposit date:2022-05-02
Release date:2022-08-31
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM reveals an entangled kinetic trap in the folding of a catalytic RNA.
Sci Adv, 8, 2022
7JJU
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BU of 7jju by Molmil
Crystal structure of en exoribonuclease-resistant RNA (xrRNA) from Potato leafroll virus (PLRV)
Descriptor: CACODYLATE ION, Guanidinium, IRIDIUM HEXAMMINE ION, ...
Authors:Steckelberg, A.-L, Vicens, Q, Auffinger, P, Costantino, D.C, Nix, J.C, Kieft, J.S.
Deposit date:2020-07-27
Release date:2020-09-09
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold.
Rna, 26, 2020
2ET5
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BU of 2et5 by Molmil
Complex Between Ribostamycin and the 16S-RRNA A-Site
Descriptor: 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', RIBOSTAMYCIN, SULFATE ION
Authors:Westhof, E.
Deposit date:2005-10-27
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding.
Nucleic Acids Res., 33, 2005
5NKO
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BU of 5nko by Molmil
Solution structure of the C-terminal domain of S. aureus Hibernating Promoting Factor (CTD-SaHPF)
Descriptor: Ribosome hibernation promotion factor
Authors:Usachev, K.S, Khusainov, I.S, Ayupov, R.K, Validov, S.Z, Kieffer, B, Yusupov, M.M.
Deposit date:2017-03-31
Release date:2017-07-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF.
EMBO J., 36, 2017
2ET8
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BU of 2et8 by Molmil
Complex Between Neamine and the 16S-RRNA A-Site
Descriptor: (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside, 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'
Authors:Westhof, E.
Deposit date:2005-10-27
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding.
Nucleic Acids Res., 33, 2005
2ESI
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BU of 2esi by Molmil
Complex between Kanamycin A and the 16S-Rrna A Site.
Descriptor: 5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', KANAMYCIN A
Authors:Westhof, E.
Deposit date:2005-10-26
Release date:2005-12-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding
Nucleic Acids Res., 33, 2005
2ET3
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BU of 2et3 by Molmil
Complex Between Gentamicin C1A and the 16S-RRNA A-Site
Descriptor: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'
Authors:Westhof, E.
Deposit date:2005-10-27
Release date:2005-12-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding.
Nucleic Acids Res., 33, 2005
2ESJ
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BU of 2esj by Molmil
Complex between Lividomycin A and the 16S-Rrna A Site
Descriptor: (2R,3S,4S,5S,6R)-2-((2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3S,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R ,5S,6R)-3-AMINO-5-HYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-4-HYDROXY-2-(HYDROXYMET HYL)-TETRAHYDROFURAN-3-YLOXY)-4-HYDROXY-TETRAHYDRO-2H-PYRAN-3-YLOXY)-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL, 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'
Authors:Westhof, E.
Deposit date:2005-10-26
Release date:2005-12-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding
Nucleic Acids Res., 33, 2005

 

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