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6OF1
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BU of 6of1 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with dirithromycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.80A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Khabibullina, N.F, Tereshchenkov, A.G, Komarova, E.S, Syroegin, E.A, Shiriaev, D.I, Paleskava, A, Kartsev, V.G, Bogdanov, A.A, Konevega, A.L, Dontsova, O.A, Sergiev, P.V, Osterman, I.A, Polikanov, Y.S.
Deposit date:2019-03-28
Release date:2019-04-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Dirithromycin Bound to the Bacterial Ribosome Suggests New Ways for Rational Improvement of Macrolides.
Antimicrob.Agents Chemother., 63, 2019
6XZA
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BU of 6xza by Molmil
E. coli 70S ribosome in complex with dirithromycin, and deacylated tRNA(iMet) (focused classification).
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L.
Deposit date:2020-02-03
Release date:2020-11-04
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome.
Rna, 26, 2020
6XZB
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BU of 6xzb by Molmil
E. coli 70S ribosome in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet) (focused classification).
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L.
Deposit date:2020-02-03
Release date:2020-11-04
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome.
Rna, 26, 2020
6XZ7
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BU of 6xz7 by Molmil
E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet).
Descriptor: 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Pichkur, E.B, Polikanov, Y.S, Myasnikov, A.G, Konevega, A.L.
Deposit date:2020-02-03
Release date:2020-07-22
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to theE. coli70S ribosome.
Rna, 26, 2020
6Y6X
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BU of 6y6x by Molmil
Tetracenomycin X bound to the human ribosome
Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Buschauer, R, Cheng, J, Berninghausen, O, Beckmann, R, Wilson, D.N.
Deposit date:2020-02-27
Release date:2020-07-08
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020
6Y69
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BU of 6y69 by Molmil
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Wieland, M, Wilson, D.N.
Deposit date:2020-02-26
Release date:2020-07-01
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020

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