Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
5TJ6
DownloadVisualize
BU of 5tj6 by Molmil
Ca2+ bound aplysia Slo1
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, High conductance calcium-activated potassium channel, ...
Authors:MacKinnon, R, Tao, X, Hite, R.K.
Deposit date:2016-10-03
Release date:2016-12-14
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of the open high-conductance Ca(2+)-activated K(+) channel.
Nature, 541, 2017
5TJI
DownloadVisualize
BU of 5tji by Molmil
Ca2+ bound aplysia Slo1
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, High conductance calcium-activated potassium channel
Authors:MacKinnon, R, Tao, X, Hite, R.K.
Deposit date:2016-10-04
Release date:2016-12-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for gating the high-conductance Ca(2+)-activated K(+) channel.
Nature, 541, 2017
6V00
DownloadVisualize
BU of 6v00 by Molmil
structure of human KCNQ1-KCNE3-CaM complex
Descriptor: CALCIUM ION, Calmodulin-1, MCherry fluorescent protein,Potassium voltage-gated channel subfamily E member 3, ...
Authors:Mackinnon, R, Sun, J.
Deposit date:2019-11-16
Release date:2019-12-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural Basis of Human KCNQ1 Modulation and Gating.
Cell, 180, 2020
6UZZ
DownloadVisualize
BU of 6uzz by Molmil
structure of human KCNQ1-CaM complex
Descriptor: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1
Authors:Mackinnon, R, Sun, J.
Deposit date:2019-11-16
Release date:2019-12-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural Basis of Human KCNQ1 Modulation and Gating.
Cell, 180, 2020
6V01
DownloadVisualize
BU of 6v01 by Molmil
structure of human KCNQ1-KCNE3-CaM complex with PIP2
Descriptor: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily E member 3, ...
Authors:Mackinnon, R, Sun, J.
Deposit date:2019-11-18
Release date:2019-12-04
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Basis of Human KCNQ1 Modulation and Gating.
Cell, 180, 2020
5VMS
DownloadVisualize
BU of 5vms by Molmil
CryoEM structure of Xenopus KCNQ1 channel
Descriptor: CALCIUM ION, Calmodulin, Potassium voltage-gated channel subfamily KQT member 1
Authors:Mackinnon, R, Sun, J.
Deposit date:2017-04-28
Release date:2017-06-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome.
Cell, 169, 2017
4JTA
DownloadVisualize
BU of 4jta by Molmil
Crystal structure of Kv1.2-2.1 paddle chimera channel in complex with Charybdotoxin
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ...
Authors:MacKinnon, R, Banerjee, A, Lee, A, Campbell, E.
Deposit date:2013-03-23
Release date:2013-06-12
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K(+) channel.
Elife, 2, 2013
1S5H
DownloadVisualize
BU of 1s5h by Molmil
Potassium Channel Kcsa-Fab Complex T75C mutant in K+
Descriptor: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, DIACYL GLYCEROL, ...
Authors:Mackinnon, R, Zhou, M.
Deposit date:2004-01-20
Release date:2004-05-18
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A mutant KcsA K(+) channel with altered conduction properties and selectivity filter ion distribution.
J.Mol.Biol., 338, 2004
1AGT
DownloadVisualize
BU of 1agt by Molmil
SOLUTION STRUCTURE OF THE POTASSIUM CHANNEL INHIBITOR AGITOXIN 2: CALIPER FOR PROBING CHANNEL GEOMETRY
Descriptor: AGITOXIN 2
Authors:Krezel, A.M, Kasibhatla, C, Hidalgo, P, Mackinnon, R, Wagner, G.
Deposit date:1995-04-14
Release date:1995-07-10
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry.
Protein Sci., 4, 1995
5K7L
DownloadVisualize
BU of 5k7l by Molmil
Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 bound to the channel inhibitor calmodulin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Calmodulin, ...
Authors:Whicher, J.R, MacKinnon, R.
Deposit date:2016-05-26
Release date:2016-08-17
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Structure of the voltage-gated K+ channel Eag1 reveals an alternative voltage sensing mechanism.
Science, 353, 2016
4WFG
DownloadVisualize
BU of 4wfg by Molmil
Human TRAAK K+ channel in a Tl+ bound conductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Brohawn, S.G, MacKinnon, R.
Deposit date:2014-09-15
Release date:2014-12-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
4WFH
DownloadVisualize
BU of 4wfh by Molmil
Human TRAAK K+ channel in a Tl+ bound nonconductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Brohawn, S.G, MacKinnon, R.
Deposit date:2014-09-15
Release date:2014-12-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
4WFE
DownloadVisualize
BU of 4wfe by Molmil
Human TRAAK K+ channel in a K+ bound conductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Brohawn, S.G, MacKinnon, R.
Deposit date:2014-09-15
Release date:2014-12-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
4WFF
DownloadVisualize
BU of 4wff by Molmil
Human TRAAK K+ channel in a K+ bound nonconductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Brohawn, S.G, MacKinnon, R.
Deposit date:2014-09-15
Release date:2014-12-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel.
Nature, 516, 2014
6B3R
DownloadVisualize
BU of 6b3r by Molmil
Structure of the mechanosensitive channel Piezo1
Descriptor: Piezo-type mechanosensitive ion channel component 1, unknown fragment
Authors:Guo, Y.R, MacKinnon, R.
Deposit date:2017-09-22
Release date:2017-12-20
Last modified:2018-05-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure-based membrane dome mechanism for Piezo mechanosensitivity.
Elife, 6, 2017
1BFE
DownloadVisualize
BU of 1bfe by Molmil
THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95
Descriptor: PSD-95
Authors:Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
Deposit date:1998-05-20
Release date:1998-10-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
1BE9
DownloadVisualize
BU of 1be9 by Molmil
THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT.
Descriptor: CRIPT, PSD-95
Authors:Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
Deposit date:1998-05-20
Release date:1998-10-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ.
Cell(Cambridge,Mass.), 85, 1996
1BL8
DownloadVisualize
BU of 1bl8 by Molmil
POTASSIUM CHANNEL (KCSA) FROM STREPTOMYCES LIVIDANS
Descriptor: POTASSIUM ION, PROTEIN (POTASSIUM CHANNEL PROTEIN)
Authors:Doyle, D.A, Cabral, J.M, Pfuetzner, R.A, Kuo, A, Gulbis, J.M, Cohen, S.L, Chait, B.T, Mackinnon, R.
Deposit date:1998-07-23
Release date:1998-07-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structure of the potassium channel: molecular basis of K+ conduction and selectivity.
Science, 280, 1998
1BYW
DownloadVisualize
BU of 1byw by Molmil
STRUCTURE OF THE N-TERMINAL DOMAIN OF THE HUMAN-ERG POTASSIUM CHANNEL
Descriptor: PROTEIN (HUMAN ERG POTASSIUM CHANNEL)
Authors:Cabral, J.H.M, Lee, A, Mackinnon, R.
Deposit date:1998-10-15
Release date:1998-12-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure and Functional Analysis of the Herg Potassium Channel N-Terminus: A Eukaryotic Pas Domain
Cell(Cambridge,Mass.), 95, 1998
8SIK
DownloadVisualize
BU of 8sik by Molmil
KCNQ1 with voltage sensor in the up conformation
Descriptor: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1
Authors:Mandala, V.S, MacKinnon, R.
Deposit date:2023-04-16
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The membrane electric field regulates the PIP 2 -binding site to gate the KCNQ1 channel.
Proc.Natl.Acad.Sci.USA, 120, 2023
8SIM
DownloadVisualize
BU of 8sim by Molmil
KCNQ1 with voltage sensor in the intermediate conformation
Descriptor: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1
Authors:Mandala, V.S, MacKinnon, R.
Deposit date:2023-04-16
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:The membrane electric field regulates the PIP 2 -binding site to gate the KCNQ1 channel.
Proc.Natl.Acad.Sci.USA, 120, 2023
8SIN
DownloadVisualize
BU of 8sin by Molmil
KCNQ1 with voltage sensor in the down conformation
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1
Authors:Mandala, V.S, MacKinnon, R.
Deposit date:2023-04-16
Release date:2023-05-31
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:The membrane electric field regulates the PIP 2 -binding site to gate the KCNQ1 channel.
Proc.Natl.Acad.Sci.USA, 120, 2023
7N0L
DownloadVisualize
BU of 7n0l by Molmil
Cryo-EM structure of TACAN in the H196A H197A mutant form (TMEM120A)
Descriptor: COENZYME A, Ion channel TACAN
Authors:Niu, Y, Tao, X, MacKinnon, R.
Deposit date:2021-05-25
Release date:2021-09-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Analysis of the mechanosensor channel functionality of TACAN.
Elife, 10, 2021
7N0K
DownloadVisualize
BU of 7n0k by Molmil
Cryo-EM structure of TACAN in the apo form (TMEM120A)
Descriptor: Ion channel TACAN
Authors:Niu, Y, Tao, X, MacKinnon, R.
Deposit date:2021-05-25
Release date:2021-09-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Analysis of the mechanosensor channel functionality of TACAN.
Elife, 10, 2021
8UQN
DownloadVisualize
BU of 8uqn by Molmil
PLCb3-Gaq complex on membranes
Descriptor: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Falzone, M.E, MacKinnon, R.
Deposit date:2023-10-24
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The mechanism of G alpha q regulation of PLC beta 3 -catalyzed PIP2 hydrolysis.
Proc.Natl.Acad.Sci.USA, 120, 2023

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon