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1UW4
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BU of 1uw4 by Molmil
The structural basis of the interaction between nonsense mediated decay factors UPF2 and UPF3
Descriptor: BETA-MERCAPTOETHANOL, REGULATOR OF NONSENSE TRANSCRIPTS 2, UPF3X
Authors:Kadlec, J, Izaurralde, E, Cusack, S.
Deposit date:2004-01-29
Release date:2004-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Structural Basis for the Interaction between Nonsense-Mediated Mrna Decay Factors Upf2 and Upf3
Nat.Struct.Mol.Biol., 11, 2004
3DUZ
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BU of 3duz by Molmil
Crystal structure of the postfusion form of baculovirus fusion protein GP64
Descriptor: MERCURY (II) ION, Major envelope glycoprotein
Authors:Kadlec, J, Loureiro, S, Abrescia, N.G.A, Jones, I.M, Stuart, D.I.
Deposit date:2008-07-18
Release date:2008-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The postfusion structure of baculovirus gp64 supports a unified view of viral fusion machines.
Nat.Struct.Mol.Biol., 15, 2008
2IYK
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BU of 2iyk by Molmil
Crystal structure of the UPF2-interacting domain of nonsense mediated mRNA decay factor UPF1
Descriptor: REGULATOR OF NONSENSE TRANSCRIPTS 1, ZINC ION
Authors:Kadlec, J, Guilligay, D, Ravelli, R.B, Cusack, S.
Deposit date:2006-07-18
Release date:2006-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal Structure of the Upf2-Interacting Domain of Nonsense-Mediated Mrna Decay Factor Upf1.
RNA, 12, 2006
2Y0M
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BU of 2y0m by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN DOSAGE COMPENSATION FACTORS MSL1 AND MOF
Descriptor: ACETYL COENZYME *A, MALE-SPECIFIC LETHAL 1 HOMOLOG, PROBABLE HISTONE ACETYLTRANSFERASE MYST1, ...
Authors:Kadlec, J, Hallacli, E, Lipp, M, Holz, H, Sanchez Weatherby, J, Cusack, S, Akhtar, A.
Deposit date:2010-12-03
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for Mof and Msl3 Recruitment Into the Dosage Compensation Complex by Msl1.
Nat.Struct.Mol.Biol., 18, 2011
2Y0N
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BU of 2y0n by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN DOSAGE COMPENSATION FACTORS MSL1 AND MSL3
Descriptor: MALE-SPECIFIC LETHAL 1 HOMOLOG, MALE-SPECIFIC LETHAL 3 HOMOLOG
Authors:Kadlec, J, Hallacli, E, Lipp, M, Holz, H, Sanchez Weatherby, J, Cusack, S, Akhtar, A.
Deposit date:2010-12-04
Release date:2011-01-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for Mof and Msl3 Recruitment Into the Dosage Compensation Complex by Msl1.
Nat.Struct.Mol.Biol., 18, 2011
4UOI
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BU of 4uoi by Molmil
Unexpected structure for the N-terminal domain of Hepatitis C virus envelope glycoprotein E1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GENOME POLYPROTEIN
Authors:El Omari, K, Iourin, O, Kadlec, J, Harlos, K, Grimes, J.M, Stuart, D.I.
Deposit date:2014-06-04
Release date:2014-08-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Unexpected Structure for the N-Terminal Domain of Hepatitis C Virus Envelope Glycoprotein E1
Acta Crystallogr.,Sect.D, 70, 2014
7QWV
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BU of 7qwv by Molmil
Crystal structure of the REC114-TOPOVIBL complex.
Descriptor: Meiotic recombination protein REC114, Type 2 DNA topoisomerase 6 subunit B-like
Authors:Juarez-Martinez, A.B, Robert, T, de Massy, B, Kadlec, J.
Deposit date:2022-01-25
Release date:2023-02-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:TOPOVIBL-REC114 interaction regulates meiotic DNA double-strand breaks.
Nat Commun, 13, 2022
8BY6
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BU of 8by6 by Molmil
Structure of the human nuclear cap-binding complex bound to NCBP3(560-620) and cap-analogue m7GpppG
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ...
Authors:Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J.
Deposit date:2022-12-12
Release date:2024-01-24
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex.
Cell Rep, 43, 2024
5O8M
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BU of 5o8m by Molmil
Crystal structure of the MmI1 YTH domain
Descriptor: GLYCEROL, YTH domain-containing protein mmi1
Authors:Brettschneider, J, Verdel, A, Kadlec, J.
Deposit date:2017-06-13
Release date:2018-04-25
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation.
EMBO J., 36, 2017
7QUU
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BU of 7quu by Molmil
Red1-Iss10 complex
Descriptor: NURS complex subunit red1, Uncharacterized protein C7D4.14c
Authors:Mackereth, C.D, Kadlec, J, Laroussi, H.
Deposit date:2022-01-18
Release date:2022-09-07
Last modified:2022-11-16
Method:SOLUTION NMR
Cite:Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex.
Nat Commun, 13, 2022
7QY5
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BU of 7qy5 by Molmil
Crystal structure of the S.pombe Ars2-Red1 complex.
Descriptor: NURS complex subunit pir2, RNA elimination defective protein Red1, ZINC ION
Authors:Foucher, A.E, Kadlec, J.
Deposit date:2022-01-27
Release date:2022-11-16
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex.
Nat Commun, 13, 2022
6HFG
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BU of 6hfg by Molmil
Structure of the REC114 PH domain
Descriptor: Meiotic recombination protein REC114
Authors:Juarez-Martinez, A.B, de Massy, B, Kadlec, J.
Deposit date:2018-08-21
Release date:2019-07-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4.
Life Sci Alliance, 1, 2018
1L4A
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BU of 1l4a by Molmil
X-RAY STRUCTURE OF THE NEURONAL COMPLEXIN/SNARE COMPLEX FROM THE SQUID LOLIGO PEALEI
Descriptor: S-SNAP25 fusion protein, S-SYNTAXIN, SYNAPHIN A, ...
Authors:Bracher, A, Kadlec, J, Betz, H, Weissenhorn, W.
Deposit date:2002-03-04
Release date:2002-07-31
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:X-ray structure of a neuronal complexin-SNARE complex from squid.
J.Biol.Chem., 277, 2002
8PNT
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BU of 8pnt by Molmil
Structure of the human nuclear cap-binding complex bound to PHAX and m7G-capped RNA
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ...
Authors:Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J.
Deposit date:2023-07-01
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex.
Cell Rep, 43, 2024
8PMP
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BU of 8pmp by Molmil
Structure of the human nuclear cap-binding complex bound to ARS2[147-871] and m7GTP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ...
Authors:Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J.
Deposit date:2023-06-29
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex.
Cell Rep, 43, 2024
2WJY
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BU of 2wjy by Molmil
Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 Orthorhombic form
Descriptor: REGULATOR OF NONSENSE TRANSCRIPTS 1, SULFATE ION, ZINC ION
Authors:Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S.
Deposit date:2009-06-01
Release date:2009-07-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2.
Embo J., 28, 2009
2WJV
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BU of 2wjv by Molmil
Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2
Descriptor: REGULATOR OF NONSENSE TRANSCRIPTS 1, REGULATOR OF NONSENSE TRANSCRIPTS 2, SULFATE ION, ...
Authors:Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S.
Deposit date:2009-06-01
Release date:2009-07-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2.
Embo J., 28, 2009
4CY1
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BU of 4cy1 by Molmil
Crystal structure of the KANSL1-WDR5 complex.
Descriptor: GLYCEROL, KAT8 REGULATORY NSL COMPLEX SUBUNIT 1, WD REPEAT-CONTAINING PROTEIN 5
Authors:Dias, J, Brettschneider, J, Cusack, S, Kadlec, J.
Deposit date:2014-04-09
Release date:2014-05-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
4CY2
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BU of 4cy2 by Molmil
Crystal structure of the KANSL1-WDR5-KANSL2 complex.
Descriptor: KAT8 REGULATORY NSL COMPLEX SUBUNIT 1, KAT8 REGULATORY NSL COMPLEX SUBUNIT 2, WD REPEAT-CONTAINING PROTEIN 5
Authors:Dias, J, Brettschneider, J, Cusack, S, Kadlec, J.
Deposit date:2014-04-09
Release date:2014-05-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
4CY5
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BU of 4cy5 by Molmil
Crystal structure of the NSL1-WDS-NSL2 complex.
Descriptor: CG4699, ISOFORM D, DIM GAMMA-TUBULIN 1, ...
Authors:Dias, J, Brettschneider, J, Cusack, S, Kadlec, J.
Deposit date:2014-04-10
Release date:2014-05-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
4CY3
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BU of 4cy3 by Molmil
Crystal structure of the NSL1-WDS complex.
Descriptor: CG4699, ISOFORM D, GLYCEROL, ...
Authors:Dias, J, Brettschneider, J, Cusack, S, Kadlec, J.
Deposit date:2014-04-10
Release date:2014-05-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.
Genes Dev., 28, 2014
4D26
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BU of 4d26 by Molmil
Crystal structure of the Bombyx mori Vasa helicase (E339Q) in complex with RNA,ADP and Pi
Descriptor: 5'-R(*UP*GP*AP*CP*AP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, BMVLG PROTEIN, ...
Authors:Spinelli, P, Pillai, R.S, Kadlec, J, Cusack, S.
Deposit date:2014-05-07
Release date:2014-06-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:RNA Clamping by Vasa Assembles a Pirna Amplifier Complex on Transposon Transcripts.
Cell(Cambridge,Mass.), 157, 2014
4D25
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BU of 4d25 by Molmil
Crystal structure of the Bombyx mori Vasa helicase (E339Q) in complex with RNA and AMPPNP
Descriptor: 5'-R(*UP*GP*AP*CP*AP*UP)-3', BMVLG PROTEIN, GLYCEROL, ...
Authors:Spinelli, P, Pillai, R.S, Kadlec, J, Cusack, S.
Deposit date:2014-05-07
Release date:2014-06-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:RNA Clamping by Vasa Assembles a Pirna Amplifier Complex on Transposon Transcripts.
Cell(Cambridge,Mass.), 157, 2014
4B9W
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BU of 4b9w by Molmil
Structure of extended Tudor domain TD3 from mouse TDRD1 in complex with MILI peptide containing dimethylarginine 45.
Descriptor: GLYCEROL, PIWI-LIKE PROTEIN 2, TUDOR DOMAIN-CONTAINING PROTEIN 1
Authors:Mathioudakis, N, Palencia, A, Kadlec, J, Round, A, Tripsianes, K, Sattler, M, Pillai, R.S, Cusack, S.
Deposit date:2012-09-08
Release date:2012-10-17
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors.
Rna, 18, 2012
4B86
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BU of 4b86 by Molmil
Crystal structure of the MSL1-MSL2 complex (3.5A)
Descriptor: MALE-SPECIFIC LETHAL 1 HOMOLOG, MALE-SPECIFIC LETHAL 2 HOMOLOG, ZINC ION
Authors:Hallacli, E, Lipp, M, Georgiev, P, Spielman, C, Cusack, S, Akhtar, A, Kadlec, J.
Deposit date:2012-08-24
Release date:2013-02-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Msl1-Mediated Dimerization of the Dosage Compensation Complex is Essential for Male X-Chromosome Regulation in Drosophila.
Mol.Cell, 48, 2012

 

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