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1R7R
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BU of 1r7r by Molmil
The crystal structure of murine p97/VCP at 3.6A
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
Authors:Huyton, T, Pye, V.E, Briggs, L.C, Flynn, T.C, Beuron, F, Kondo, H, Ma, J, Zhang, X, Freemont, P.S.
Deposit date:2003-10-22
Release date:2003-12-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The crystal structure of murine p97/VCP at 3.6A
J.Struct.Biol., 144, 2003
7ZAL
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BU of 7zal by Molmil
FNIP family proteins from Cafeteria roenbergensis virus (CroV): leucine-rich repeats with novel structural features
Descriptor: Crov539
Authors:Huyton, T, Goerlich, D.
Deposit date:2022-03-22
Release date:2022-08-24
Last modified:2022-10-26
Method:X-RAY DIFFRACTION (2.732 Å)
Cite:Crystal structures of FNIP/FGxxFN motif-containing leucine-rich repeat proteins.
Sci Rep, 12, 2022
2Q7N
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BU of 2q7n by Molmil
Crystal structure of Leukemia inhibitory factor in complex with LIF receptor (domains 1-5)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Huyton, T, Zhang, J.G, Nicola, N.A, Garrett, T.P.J.
Deposit date:2007-06-07
Release date:2007-07-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (4 Å)
Cite:An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor.
Proc.Natl.Acad.Sci.USA, 104, 2007
6NYR
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BU of 6nyr by Molmil
The crystal structure of CroV588 a novel circular LRR protein structure
Descriptor: Crov588, GLYCEROL
Authors:Huyton, T, Jaiswal, M, Gorlich, D.
Deposit date:2019-02-12
Release date:2020-08-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.431 Å)
Cite:The crystal structure of CroV588 a novel circular LRR protein structure
To Be Published
6NYS
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BU of 6nys by Molmil
The crystal structure of CroV588 a novel circular LRR protein structure
Descriptor: 6-tungstotellurate(VI), crov588
Authors:Huyton, T, Jaiswal, M, Gorlich, D.
Deposit date:2019-02-12
Release date:2020-08-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The crystal structure of CroV588 a novel circular LRR protein structure
To Be Published
2JE0
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BU of 2je0 by Molmil
Crystal Structure of pp32
Descriptor: ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A, GLYCEROL
Authors:Huyton, T, Wolberger, C.
Deposit date:2007-01-12
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of the Tumor Suppressor Protein Pp32 (Anp32A): Structural Insights Into Anp32 Family of Proteins.
Protein Sci., 16, 2007
2JE1
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BU of 2je1 by Molmil
The crystal Structure of the tumor supressor protein pp32 (Anp32a) :structural insights into the Anp32 family of proteins
Descriptor: ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A, GLYCEROL
Authors:Huyton, T, Wolberger, C.
Deposit date:2007-01-12
Release date:2007-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:The Crystal Structure of the Tumor Suppressor Protein Pp32 (Anp32A): Structural Insights Into Anp32 Family of Proteins.
Protein Sci., 16, 2007
5MSE
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BU of 5mse by Molmil
GFP nuclear transport receptor mimic 3B8
Descriptor: Green fluorescent protein, IMIDAZOLE, SODIUM ION
Authors:Huyton, T, Gorlich, D.
Deposit date:2017-01-04
Release date:2018-05-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Surface Properties Determining Passage Rates of Proteins through Nuclear Pores.
Cell, 174, 2018
6QUG
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BU of 6qug by Molmil
GHK tagged MBP-Nup98(1-29)
Descriptor: COPPER (II) ION, Maltodextrin-binding protein,Nucleoporin, putative, ...
Authors:Huyton, T, Gorlich, D.
Deposit date:2019-02-27
Release date:2020-05-27
Last modified:2020-12-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The copper(II)-binding tripeptide GHK, a valuable crystallization and phasing tag for macromolecular crystallography.
Acta Crystallogr D Struct Biol, 76, 2020
6QUI
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BU of 6qui by Molmil
GHK tagged GFP variant at 17Kev
Descriptor: COPPER (II) ION, GLYCEROL, Green fluorescent protein, ...
Authors:Huyton, T, Gorlich, D.
Deposit date:2019-02-27
Release date:2020-05-27
Last modified:2022-12-07
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The copper(II)-binding tripeptide GHK, a valuable crystallization and phasing tag for macromolecular crystallography.
Acta Crystallogr D Struct Biol, 76, 2020
6QUH
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BU of 6quh by Molmil
GHK tagged GFP variant crystal form II at 1.34A wavelength
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, COPPER (II) ION, ...
Authors:Huyton, T, Gorlich, D.
Deposit date:2019-02-27
Release date:2020-05-27
Last modified:2022-12-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The copper(II)-binding tripeptide GHK, a valuable crystallization and phasing tag for macromolecular crystallography.
Acta Crystallogr D Struct Biol, 76, 2020
6QUJ
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BU of 6quj by Molmil
GHK tagged GFP variant
Descriptor: COPPER (II) ION, GLYCEROL, Green fluorescent protein, ...
Authors:Huyton, T, Gorlich, D.
Deposit date:2019-02-27
Release date:2020-05-27
Last modified:2022-12-07
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:The copper(II)-binding tripeptide GHK, a valuable crystallization and phasing tag for macromolecular crystallography.
Acta Crystallogr D Struct Biol, 76, 2020
7NQ6
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BU of 7nq6 by Molmil
High resolution crystal structure of C-terminal domain (residues 715-866) of Nucleoporin-98
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Nuclear pore complex protein Nup96, ...
Authors:Trakhanov, S, Goerlich, D, Huyton, T.
Deposit date:2021-03-01
Release date:2021-04-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High resolution crystal structure of C-terminal domain (residues 715-866) of Nucleoporin-98
To Be Published
6FVB
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BU of 6fvb by Molmil
Structure of Lph2 , a novel bidirectional nuclear transport receptor in S. cerevisiae
Descriptor: Importin beta-like protein KAP120
Authors:Vera Rodriguez, A, Huyton, T, Gorlich, D.
Deposit date:2018-03-01
Release date:2019-09-11
Method:X-RAY DIFFRACTION (3.297 Å)
Cite:Structure of Lph2 , a novel bidirectional nuclear transport receptor in S. cerevisiae
To Be Published
1GQZ
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BU of 1gqz by Molmil
Refinement of Haemophilus influenzae Diaminopimelate epimerase at 1.7A
Descriptor: DIAMINOPIMELATE EPIMERASE
Authors:Roper, D.I, Huyton, T, Turkenburg, J.P.
Deposit date:2001-12-07
Release date:2003-06-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Refinement of Haemophilus influenzae diaminopimelic acid epimerase (DapF) at 1.75 A resolution suggests a mechanism for stereocontrol during catalysis.
Acta Crystallogr. D Biol. Crystallogr., 60, 2004
3CDG
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BU of 3cdg by Molmil
Human CD94/NKG2A in complex with HLA-E
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, alpha chain E, ...
Authors:Petrie, E.J, Clements, C.S, Lin, J, Sullivan, L.C, Johnson, D, Huyton, T, Heroux, A, Hoare, H.L, Beddoe, T, Reid, H.H, Wilce, M.C.J, Brooks, A.G, Rossjohn, J.
Deposit date:2008-02-26
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence
J.Exp.Med., 205, 2008
2B8H
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BU of 2b8h by Molmil
A/NWS/whale/Maine/1/84 (H1N9) reassortant influenza virus neuraminidase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Smith, B.J, Platis, D, Cox, M.M.J, Huyton, T, Joosten, R.P, McKimm-Breschkin, J.L, Zhang, J.-G, Luo, C.S, Lou, M.-Z, Garrett, T.P.J, Labrou, N.E.
Deposit date:2005-10-07
Release date:2006-09-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a calcium-deficient form of influenza virus neuraminidase: implications for substrate binding.
Acta Crystallogr.,Sect.D, 62, 2006
2BN8
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BU of 2bn8 by Molmil
Solution Structure and interactions of the E .coli Cell Division Activator Protein CedA
Descriptor: CELL DIVISION ACTIVATOR CEDA
Authors:Chen, H.A, Simpson, P, Huyton, T, Roper, D, Matthews, S.
Deposit date:2005-03-22
Release date:2006-12-21
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:Solution Structure and Interactions of the Escherichia Coli Cell Division Activator Protein Ceda.
Biochemistry, 44, 2005
3G5V
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BU of 3g5v by Molmil
Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR
Descriptor: 806 light chain, 808 heavy chain, ACETATE ION, ...
Authors:Garrett, T.P.J, Burgess, A.W, Huyton, T, Xu, Y.
Deposit date:2009-02-05
Release date:2010-02-09
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Antibodies specifically targeting a locally misfolded region of tumor associated EGFR
Proc.Natl.Acad.Sci.USA, 106, 2009
1E4E
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BU of 1e4e by Molmil
D-alanyl-D-lacate ligase
Descriptor: 1(S)-AMINOETHYL-(2-CARBOXYPROPYL)PHOSPHORYL-PHOSPHINIC ACID, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
Authors:Roper, D.I.
Deposit date:2000-07-03
Release date:2001-06-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The molecular basis of vancomycin resistance in clinically relevant Enterococci: crystal structure of D-alanyl-D-lactate ligase (VanA).
Proc. Natl. Acad. Sci. U.S.A., 97, 2000
3LN5
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BU of 3ln5 by Molmil
Crystal structure of HLA-B*4104 in complex with a 11mer self-peptide derived from S-methyl-5-thioadenosine phosphorylase
Descriptor: 11-mer peptide from S-methyl-5'-thioadenosine phosphorylase, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Theodossis, A, Gras, S, Rossjohn, J.
Deposit date:2010-02-02
Release date:2010-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family
Haematologica, 96, 2011
3BDW
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BU of 3bdw by Molmil
Human CD94/NKG2A
Descriptor: NKG2-A/NKG2-B type II integral membrane protein, Natural killer cells antigen CD94
Authors:Sullivan, L.C, Clements, C.S.
Deposit date:2007-11-15
Release date:2008-01-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Heterodimeric Assembly of the CD94-NKG2 Receptor Family and Implications for Human Leukocyte Antigen-E Recognition
Immunity, 27, 2007
3FX4
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BU of 3fx4 by Molmil
Porcine aldehyde reductase in ternary complex with inhibitor
Descriptor: Alcohol dehydrogenase [NADP+], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ...
Authors:Carbone, V, El-Kabbani, O.
Deposit date:2009-01-20
Release date:2009-12-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structure of aldehyde reductase in ternary complex with a 5-arylidene-2,4-thiazolidinedione aldose reductase inhibitor.
Eur.J.Med.Chem., 45, 2010
3G5X
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BU of 3g5x by Molmil
Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR
Descriptor: 806 heavy chain, 806 light chain
Authors:Garrett, T.P.J, Burgess, A.W.
Deposit date:2009-02-05
Release date:2009-12-15
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Antibodies specifically targeting a locally misfolded region of tumor associated EGFR
Proc.Natl.Acad.Sci.USA, 106, 2009
3G5Y
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BU of 3g5y by Molmil
Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR
Descriptor: 175 heavy chain, 175 light chain, EGFR peptide
Authors:Garrett, T.P.J, Burgess, A.W.
Deposit date:2009-02-05
Release date:2010-02-09
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Antibodies specifically targeting a locally misfolded region of tumor associated EGFR
Proc.Natl.Acad.Sci.USA, 106, 2009

 

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