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1ZJW
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BU of 1zjw by Molmil
Glutaminyl-tRNA synthetase complexed to glutamine and 2'deoxy A76 glutamine tRNA
Descriptor: ADENOSINE MONOPHOSPHATE, GLUTAMINE, Glutaminyl-tRNA, ...
Authors:Gruic-Sovulj, I, Uter, N, Bullock, T, Perona, J.J.
Deposit date:2005-05-01
Release date:2005-06-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:tRNA-dependent Aminoacyl-adenylate Hydrolysis by a Nonediting Class I Aminoacyl-tRNA Synthetase.
J.Biol.Chem., 280, 2005
4CQN
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BU of 4cqn by Molmil
Crystal structure of the E.coli LeuRS-tRNA complex with the non- cognate isoleucyl adenylate analogue
Descriptor: ESCHERICHIA COLI TRNA-LEU UAA ISOACCEPTOR, LEUCINE--TRNA LIGASE, MAGNESIUM ION, ...
Authors:Palencia, A, Cusack, S, Cvetesic, N, Haslaz, I, Gruic-Sovulj, I.
Deposit date:2014-02-20
Release date:2014-07-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Physiological Target for Leurs Translational Quality Control is Norvaline
Embo J., 33, 2014
2CJ9
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BU of 2cj9 by Molmil
Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with an analog of seryladenylate
Descriptor: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, CHLORIDE ION, SERYL-TRNA SYNTHETASE, ...
Authors:Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N.
Deposit date:2006-03-29
Release date:2006-06-26
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition
Embo J., 25, 2006
2CJA
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BU of 2cja by Molmil
Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N.
Deposit date:2006-03-30
Release date:2006-06-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition
Embo J., 25, 2006
2CIM
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BU of 2cim by Molmil
Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase
Descriptor: CHLORIDE ION, PLATINUM (II) ION, SERYL-TRNA SYNTHETASE, ...
Authors:Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N.
Deposit date:2006-03-24
Release date:2006-06-26
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition
Embo J., 25, 2006
2CJB
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BU of 2cjb by Molmil
Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with serine
Descriptor: CHLORIDE ION, SERINE, SERYL-TRNA SYNTHETASE, ...
Authors:Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N.
Deposit date:2006-03-30
Release date:2006-06-26
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition
Embo J., 25, 2006
8C8W
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BU of 8c8w by Molmil
Priestia megaterium mupirocin hyper-resistant HIGH motif mutant of type 2 isoleucyl-tRNA synthetase complexed with an isoleucyl-adenylate analogue
Descriptor: D(-)-TARTARIC ACID, Isoleucine--tRNA ligase, N-[ISOLEUCINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, ...
Authors:Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I.
Deposit date:2023-01-21
Release date:2023-08-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif.
Nat Commun, 14, 2023
8C9D
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BU of 8c9d by Molmil
Priestia megaterium W130Q mutant of type 2 isoleucyl-tRNA synthetase complexed with an isoleucyl-adenylate analogue
Descriptor: D(-)-TARTARIC ACID, Isoleucine--tRNA ligase, N-[ISOLEUCINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, ...
Authors:Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I.
Deposit date:2023-01-21
Release date:2023-08-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif.
Nat Commun, 14, 2023
8C9F
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BU of 8c9f by Molmil
Priestia megaterium inactive HIGH motif mutant of type1 isoleucyl-tRNA synthetase complexed with an isoleucyl-adenylate analogue.
Descriptor: CHLORIDE ION, Isoleucine--tRNA ligase, LITHIUM ION, ...
Authors:Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I.
Deposit date:2023-01-21
Release date:2023-08-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif.
Nat Commun, 14, 2023
8C8V
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BU of 8c8v by Molmil
Priestia megaterium mupirocin-resistant isoleucyl-tRNA synthetase 2 with a fully-resolved C-terminal tRNA-binding domain complexed with an isoleucyl-adenylate analogue
Descriptor: D(-)-TARTARIC ACID, Isoleucine--tRNA ligase, N-[ISOLEUCINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, ...
Authors:Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I.
Deposit date:2023-01-21
Release date:2023-08-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif.
Nat Commun, 14, 2023
8C9E
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BU of 8c9e by Molmil
Priestia megaterium mupirocin-sensitive isoleucyl-tRNA synthetase 1 complexed with an isoleucyl-adenylate analogue
Descriptor: CHLORIDE ION, Isoleucine--tRNA ligase, LITHIUM ION, ...
Authors:Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I.
Deposit date:2023-01-21
Release date:2023-08-16
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif.
Nat Commun, 14, 2023
8C8U
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BU of 8c8u by Molmil
Priestia megaterium mupirocin-resistant isoleucyl-tRNA synthetase 2 complexed with mupirocin
Descriptor: Isoleucine--tRNA ligase, L(+)-TARTARIC ACID, MUPIROCIN, ...
Authors:Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Gruic-Sovulj, I, Ban, N.
Deposit date:2023-01-21
Release date:2023-08-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif.
Nat Commun, 14, 2023
8C9G
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BU of 8c9g by Molmil
Priestia megaterium mupirocin-sensitive isoleucyl-tRNA synthetase 1 complexed with mupirocin
Descriptor: CHLORIDE ION, GLYCEROL, Isoleucine--tRNA ligase, ...
Authors:Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I.
Deposit date:2023-01-22
Release date:2023-08-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif.
Nat Commun, 14, 2023
6GIR
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BU of 6gir by Molmil
Arabidopsis thaliana cytosolic seryl-tRNA synthetase
Descriptor: Serine--tRNA ligase, cytoplasmic
Authors:Kekez, I, Kekez, M, Rokov-Plavec, J, Matkovic-Calogovic, D.
Deposit date:2018-05-15
Release date:2019-01-02
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.343 Å)
Cite:Arabidopsis seryl-tRNA synthetase: the first crystal structure and novel protein interactor of plant aminoacyl-tRNA synthetase.
FEBS J., 286, 2019
5ON2
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BU of 5on2 by Molmil
Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation
Descriptor: 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ...
Authors:Palencia, A, Cusack, S.
Deposit date:2017-08-02
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase.
J. Mol. Biol., 430, 2018
5OMW
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BU of 5omw by Molmil
Mutant T252A of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation
Descriptor: 5'-O-(L-leucylsulfamoyl)adenosine, L-leucyl-tRNA, Leucine--tRNA ligase, ...
Authors:Palencia, A, Cusack, S.
Deposit date:2017-08-02
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase.
J. Mol. Biol., 430, 2018
5ONH
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BU of 5onh by Molmil
Quaternary complex of wild type E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation
Descriptor: 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, L-leucyl-tRNA(Leu), ...
Authors:Palencia, A, Cusack, S.
Deposit date:2017-08-03
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase.
J. Mol. Biol., 430, 2018
5ON3
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BU of 5on3 by Molmil
Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of leucine in the aminoacylation conformation
Descriptor: (2~{S})-~{N}-[(2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-oxidanyl-oxolan-3-yl]-2-azanyl-4-methyl-pentanamide, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ...
Authors:Palencia, A, Cusack, S.
Deposit date:2017-08-02
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase.
J. Mol. Biol., 430, 2018
3MF2
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BU of 3mf2 by Molmil
Crystal structure of class II aaRS homologue (Bll0957) complexed with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, Bll0957 protein, GLYCEROL, ...
Authors:Weygand-Durasevic, I, Mocibob, M, Ivic, N, Bilokapic, S, Maier, T, Luic, M, Ban, N.
Deposit date:2010-04-01
Release date:2010-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
3MEY
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BU of 3mey by Molmil
Crystal structure of class II aaRS homologue (Bll0957) complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Bll0957 protein, MAGNESIUM ION, ...
Authors:Weygand-Durasevic, I, Mocibob, M, Ivic, N, Bilokapic, S, Maier, T, Luic, M, Ban, N.
Deposit date:2010-04-01
Release date:2010-07-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
3MF1
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BU of 3mf1 by Molmil
Crystal structure of class II aaRS homologue (Bll0957) complexed with an analogue of glycyl adenylate
Descriptor: 5'-O-(glycylsulfamoyl)adenosine, Bll0957 protein, ZINC ION
Authors:Weygand-Durasevic, I, Mocibob, M, Ivic, N, Bilokapic, S, Maier, T, Luic, M, Ban, N.
Deposit date:2010-04-01
Release date:2010-07-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
7NTZ
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BU of 7ntz by Molmil
Crystal Structure of Neisseria gonorrhoeae LeuRS L550A mutant in Complex with the Reaction Intermediate Leu-AMP
Descriptor: Leucine--tRNA ligase, MAGNESIUM ION, ZINC ION, ...
Authors:Pang, L, Strelkov, S.V, Weeks, S.D.
Deposit date:2021-03-11
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip.
Commun Biol, 5, 2022
7NU4
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BU of 7nu4 by Molmil
Crystal Structure of Neisseria gonorrhoeae LeuRS
Descriptor: 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ...
Authors:Pang, L, Strelkov, S.V, Weeks, S.D.
Deposit date:2021-03-11
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip.
Commun Biol, 5, 2022
7NUA
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BU of 7nua by Molmil
Crystal Structure of Neisseria gonorrhoeae LeuRS L550G mutant
Descriptor: Leucine--tRNA ligase, MAGNESIUM ION, ZINC ION
Authors:Pang, L, Strelkov, S.V, Weeks, S.D.
Deposit date:2021-03-11
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip.
Commun Biol, 5, 2022
7NU5
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BU of 7nu5 by Molmil
Crystal Structure of Neisseria gonorrhoeae LeuRS in Complex with L-leucine
Descriptor: LEUCINE, Leucine--tRNA ligase, MAGNESIUM ION, ...
Authors:Pang, L, Strelkov, S.V, Weeks, S.D.
Deposit date:2021-03-11
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip.
Commun Biol, 5, 2022

 

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