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7ZOX
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BU of 7zox by Molmil
Nup93 in complex with xhNup93-Nb4i and xNup93-Nb2t
Descriptor: Nuclear pore complex protein Nup93, xNup93-Nb2t, xhNup93-Nb4i
Authors:Fu, Z, Guttler, T, Colom, M.S.
Deposit date:2022-04-26
Release date:2023-11-08
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Nup93 in complex with 5-Nup93 inhibitory NB and 15-Nup93 tracking NB
To Be Published
1FUG
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BU of 1fug by Molmil
S-ADENOSYLMETHIONINE SYNTHETASE
Descriptor: S-ADENOSYLMETHIONINE SYNTHETASE
Authors:Fu, Z, Markham, G.D, Takusagawa, F.
Deposit date:1996-02-25
Release date:1996-08-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Flexible loop in the structure of S-adenosylmethionine synthetase crystallized in the tetragonal modification.
J.Biomol.Struct.Dyn., 13, 1996
2CW6
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BU of 2cw6 by Molmil
Crystal Structure of Human HMG-CoA Lyase: Insights into Catalysis and the Molecular Basis for Hydroxymethylglutaric Aciduria
Descriptor: 3-HYDROXYPENTANEDIOIC ACID, Hydroxymethylglutaryl-CoA lyase, mitochondrial, ...
Authors:Fu, Z, Runquist, J.A, Hunt, J.F, Miziorko, H.M, Kim, J.-J.P.
Deposit date:2005-06-17
Release date:2005-12-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human 3-hydroxy-3-methylglutaryl-CoA Lyase: insights into catalysis and the molecular basis for hydroxymethylglutaric aciduria
J.Biol.Chem., 281, 2006
1KVK
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BU of 1kvk by Molmil
The Structure of Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, mevalonate kinase
Authors:Fu, Z, Wang, M, Potter, D, Mizioko, H.M, Kim, J.J.
Deposit date:2002-01-26
Release date:2002-03-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of a Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
J.Biol.Chem., 277, 2002
3FUQ
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BU of 3fuq by Molmil
Glycosylated SV2 and Gangliosides as Dual Receptors for Botulinum Neurotoxin Serotype F
Descriptor: BoNT/F (Neurotoxin type F)
Authors:Fu, Z, Chen, C, Barbieri, J.T, Kim, J.-J.P, Baldwin, M.R.
Deposit date:2009-01-14
Release date:2009-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F
Biochemistry, 48, 2009
6OSK
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BU of 6osk by Molmil
RF1 accommodated 70S complex at 60 ms
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
Deposit date:2019-05-01
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6ORE
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BU of 6ore by Molmil
Release complex 70S
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fu, Z.
Deposit date:2019-04-30
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OSQ
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BU of 6osq by Molmil
RF1 accommodated state bound Release complex 70S at long incubation time point
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
Deposit date:2019-05-02
Release date:2019-06-26
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OUO
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BU of 6ouo by Molmil
RF2 accommodated state bound 70S complex at long incubation time
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
Deposit date:2019-05-05
Release date:2019-06-19
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
2G7P
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BU of 2g7p by Molmil
Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors
Descriptor: Botulinum neurotoxin type A, ZINC ION
Authors:Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2006-08-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
2G7N
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BU of 2g7n by Molmil
Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to small Molecule Inhibitors
Descriptor: Botulinum neurotoxin type A, SILVER ION, ZINC ION
Authors:Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Light Chain of Botulinum Neurotoxin Serotype A bound to Small Molecule Inhibitors
To be Published
2G7K
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BU of 2g7k by Molmil
Structure of the Light Chain of Botulinum Neurotoxin, Serotype A Bound to small Molecule Inhibitors
Descriptor: Botulinum neurotoxin type A
Authors:Fu, Z, Baldwin, M.R, Boldt, G.E, Crawford, A, Janda, K.D, Barbieri, J.T, Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2006-08-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
2G7Q
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BU of 2g7q by Molmil
Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors
Descriptor: Botulinum neurotoxin type A, N-HYDROXY-L-ARGININAMIDE, ZINC ION
Authors:Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2006-08-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
1XVA
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BU of 1xva by Molmil
METHYLTRANSFERASE
Descriptor: ACETATE ION, GLYCINE N-METHYLTRANSFERASE, S-ADENOSYLMETHIONINE
Authors:Fu, Z, Hu, Y, Konishi, K, Takata, Y, Ogawa, H, Gomi, T, Fujioka, M, Takusagawa, F.
Deposit date:1996-07-20
Release date:1997-01-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of glycine N-methyltransferase from rat liver.
Biochemistry, 35, 1996
3FUO
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BU of 3fuo by Molmil
The Crystal structure of receptor binding domain of botulinum neurotoxin serotype A
Descriptor: Botulinum neurotoxin type A
Authors:Fu, Z, Chen, C, Barbieri, J.T, Kim, J.-J.P, Baldwin, M.R.
Deposit date:2009-01-14
Release date:2009-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F
Biochemistry, 48, 2009
3MP4
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BU of 3mp4 by Molmil
Crystal structure of Human lyase R41M mutant
Descriptor: Hydroxymethylglutaryl-CoA lyase
Authors:Fu, Z, Runquist, J.A, Montgomery, C, Miziorko, H.M, Kim, J.-J.P.
Deposit date:2010-04-24
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
3MP3
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BU of 3mp3 by Molmil
Crystal Structure of Human Lyase in complex with inhibitor HG-CoA
Descriptor: (3R,5S,9R,21S)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9,21-tetrahydroxy-8,8-dimethyl-10,14,19-trioxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide, 3-HYDROXYPENTANEDIOIC ACID, Hydroxymethylglutaryl-CoA lyase, ...
Authors:Fu, Z, Runquist, J.A, Montgomery, C, Miziorko, H.M, Kim, J.-J.P.
Deposit date:2010-04-24
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
3MP5
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BU of 3mp5 by Molmil
Crystal Structure of Human Lyase R41M in complex with HMG-CoA
Descriptor: 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, Hydroxymethylglutaryl-CoA lyase, MAGNESIUM ION
Authors:Fu, Z, Runquist, J.A, Montgomery, C, Miziorko, H.M, Kim, J.-J.P.
Deposit date:2010-04-24
Release date:2010-06-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
2R42
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BU of 2r42 by Molmil
The Biochemical and Structural Basis for feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism
Descriptor: MAGNESIUM ION, Mevalonate kinase, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE
Authors:Fu, Z, Voynova, N.E, Miziorko, H.M, Kim, J.P.
Deposit date:2007-08-30
Release date:2008-06-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism.
Biochemistry, 47, 2008
2R3V
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BU of 2r3v by Molmil
The Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism
Descriptor: Mevalonate kinase
Authors:Fu, Z, Voynova, N.E, Miziorko, H.M, Kim, J.P.
Deposit date:2007-08-30
Release date:2008-06-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism.
Biochemistry, 47, 2008
7CJM
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BU of 7cjm by Molmil
SARS CoV-2 PLpro in complex with GRL0617
Descriptor: 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, Non-structural protein 3, ZINC ION
Authors:Fu, Z, Huang, H.
Deposit date:2020-07-11
Release date:2020-09-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery.
Nat Commun, 12, 2021
8GXR
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BU of 8gxr by Molmil
crystal structure of UBC domain of UBE2O
Descriptor: (E3-independent) E2 ubiquitin-conjugating enzyme UBE2O, CITRIC ACID
Authors:Fu, Z, Zhu, W, Huang, H.
Deposit date:2022-09-21
Release date:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:crystal structure of UBE2O
To Be Published
6ORL
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BU of 6orl by Molmil
RF1 pre-accommodated 70S complex at 24 ms
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
Deposit date:2019-04-30
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OT3
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BU of 6ot3 by Molmil
RF2 accommodated state bound Release complex 70S at 24 ms
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
Deposit date:2019-05-02
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OST
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BU of 6ost by Molmil
RF2 pre-accommodated state bound Release complex 70S at 24ms
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
Deposit date:2019-05-02
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019

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