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6QW6
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BU of 6qw6 by Molmil
Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution.
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Charenton, C, Wilkinson, M.E, Nagai, K.
Deposit date:2019-03-05
Release date:2019-04-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
6QX9
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BU of 6qx9 by Molmil
Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Charenton, C, Wilkinson, M.E, Nagai, K.
Deposit date:2019-03-07
Release date:2019-04-17
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
5LM5
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BU of 5lm5 by Molmil
Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator bound to Dcp2 HLM2 peptide (region 435-451)
Descriptor: DNA topoisomerase 2-associated protein PAT1, mRNA decapping protein 2
Authors:Charenton, C, Gaudon-Plesse, C, Fourati, Z, Taverniti, V, Back, R, Kolesnikova, O, Seraphin, B, Graille, M.
Deposit date:2016-07-29
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LMG
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BU of 5lmg by Molmil
Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator bound to Dcp2 HLM10 peptide (region 954-970)
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA topoisomerase 2-associated protein PAT1, ...
Authors:Charenton, C, Gaudon-Plesse, C, Fourati, Z, Taverniti, V, Back, R, Kolesnikova, O, Seraphin, B, Graille, M.
Deposit date:2016-07-30
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5LOP
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BU of 5lop by Molmil
Structure of the active form of /K. lactis/ Dcp1-Dcp2-Edc3 decapping complex bound to m7GDP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, KLLA0A11308p, KLLA0E01827p, ...
Authors:Charenton, C, Taverniti, V, Gaudon-Plesse, C, Back, R, Seraphin, B, Graille, M.
Deposit date:2016-08-09
Release date:2016-10-05
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the active form of Dcp1-Dcp2 decapping enzyme bound to m(7)GDP and its Edc3 activator.
Nat.Struct.Mol.Biol., 23, 2016
5LON
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BU of 5lon by Molmil
Structure of /K. lactis/ Dcp1-Dcp2 decapping complex.
Descriptor: KLLA0E01827p, KLLA0F23980p
Authors:Charenton, C, Taverniti, V, Gaudon-Plesse, C, Back, R, Seraphin, B, Graille, M.
Deposit date:2016-08-09
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the active form of Dcp1-Dcp2 decapping enzyme bound to m(7)GDP and its Edc3 activator.
Nat.Struct.Mol.Biol., 23, 2016
5LMF
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BU of 5lmf by Molmil
Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator bound to Dcp2 HLM3 peptide (region 484-500)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA topoisomerase 2-associated protein PAT1, ...
Authors:Charenton, C, Gaudon-Plesse, C, Fourati, Z, Taverniti, V, Back, R, Kolesnikova, O, Seraphin, B, Graille, M.
Deposit date:2016-07-30
Release date:2017-08-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6G90
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BU of 6g90 by Molmil
Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2)
Descriptor: 56 kDa U1 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing factor 39, ...
Authors:Plaschka, C, Lin, P.-C, Charenton, C, Nagai, K.
Deposit date:2018-04-10
Release date:2018-08-22
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Prespliceosome structure provides insights into spliceosome assembly and regulation.
Nature, 559, 2018
4CVN
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BU of 4cvn by Molmil
Structure of the Fap7-Rps14 complex
Descriptor: 30S RIBOSOMAL PROTEIN S11, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Loch, J, Blaud, M, Rety, S, Lebaron, S, Deschamps, P, Bareille, J, Jombart, J, Robert-Paganin, J, Delbos, L, Chardon, F, Zhang, E, Charenton, C, Tollervey, D, Leulliot, N.
Deposit date:2014-03-28
Release date:2014-05-28
Method:X-RAY DIFFRACTION (2.121 Å)
Cite:RNA Mimicry by the Fap7 Adenylate Kinase in Ribosome Biogenesis
Plos Biol., 12, 2014
4CW7
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BU of 4cw7 by Molmil
Structure of the Fap7-Rps14 complex in complex with ATP
Descriptor: 30S RIBOSOMAL PROTEIN S11, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Loc'h, J, Blaud, M, Rety, S, Lebaron, S, Deschamps, P, Bareille, J, Jombart, J, Robert-Paganin, J, Delbos, L, Chardon, F, Zhang, E, Charenton, C, Tollervey, D, Leulliot, N.
Deposit date:2014-04-01
Release date:2014-05-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:RNA Mimicry by the Fap7 Adenylate Kinase in Ribosome Biogenesis
Plos Biol., 12, 2014
6Y3P
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BU of 6y3p by Molmil
Crystal structure of the C-terminal domain from K. lactis Pby1, an ATP-grasp enzyme interacting with the mRNA decapping enzyme Dcp2
Descriptor: KLLA0B12012p, SULFATE ION
Authors:Graille, M.
Deposit date:2020-02-18
Release date:2020-04-29
Last modified:2020-06-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Pby1 is a direct partner of the Dcp2 decapping enzyme.
Nucleic Acids Res., 48, 2020
6Y3Z
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BU of 6y3z by Molmil
Crystal structure of the Pby1 ATP-grasp enzyme bound to the S. cerevisiae mRNA decapping complex (Dcp1-Dcp2-Edc3)
Descriptor: Enhancer of mRNA-decapping protein 3, MAGNESIUM ION, Probable tubulin--tyrosine ligase PBY1, ...
Authors:Graille, M.
Deposit date:2020-02-19
Release date:2020-04-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Pby1 is a direct partner of the Dcp2 decapping enzyme.
Nucleic Acids Res., 48, 2020
5FG1
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BU of 5fg1 by Molmil
Structure of the conserved yeast listerin (Ltn1) selenomethionine-substituted N-terminal domain, TRIGONAL FORM
Descriptor: E3 ubiquitin-protein ligase listerin, POTASSIUM ION
Authors:Doamekpor, S.K, Lima, C.D.
Deposit date:2015-12-19
Release date:2016-07-06
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure and function of the yeast listerin (Ltn1) conserved N-terminal domain in binding to stalled 60S ribosomal subunits.
Proc.Natl.Acad.Sci.USA, 113, 2016
5FG0
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BU of 5fg0 by Molmil
Structure of the conserved yeast listerin (Ltn1) N-terminal domain, MONOCLINIC FORM
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase listerin, POTASSIUM ION
Authors:Doamekpor, S.K, Lima, C.D.
Deposit date:2015-12-19
Release date:2016-07-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structure and function of the yeast listerin (Ltn1) conserved N-terminal domain in binding to stalled 60S ribosomal subunits.
Proc.Natl.Acad.Sci.USA, 113, 2016
4OJJ
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BU of 4ojj by Molmil
Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator (Space group : P212121)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA topoisomerase 2-associated protein PAT1, ...
Authors:Fourati-Kammoun, Z, Kolesnikova, O, Back, R, Keller, J, Lazar, N, Gaudon-Plesse, C, Seraphin, B, Graille, M.
Deposit date:2014-01-21
Release date:2014-10-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:The C-terminal domain from S. cerevisiae Pat1 displays two conserved regions involved in decapping factor recruitment.
Plos One, 9, 2014
4OGP
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BU of 4ogp by Molmil
Structure of C-terminal domain from S. cerevisiae Pat1 decapping activator (Space group : P21)
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA topoisomerase 2-associated protein PAT1
Authors:Fourati-Kammoun, Z, Kolesnikova, O, Back, R, Keller, J, Lazar, N, Gaudon-Plesse, C, Seraphin, B, Graille, M.
Deposit date:2014-01-16
Release date:2014-10-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The C-terminal domain from S. cerevisiae Pat1 displays two conserved regions involved in decapping factor recruitment.
Plos One, 9, 2014

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