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1BRS
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BU of 1brs by Molmil
PROTEIN-PROTEIN RECOGNITION: CRYSTAL STRUCTURAL ANALYSIS OF A BARNASE-BARSTAR COMPLEX AT 2.0-A RESOLUTION
Descriptor: BARNASE, BARSTAR
Authors:Buckle, A.M, Schreiber, G, Fersht, A.R.
Deposit date:1994-03-11
Release date:1994-06-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-A resolution.
Biochemistry, 33, 1994
1KID
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BU of 1kid by Molmil
GROEL (HSP60 CLASS) FRAGMENT (APICAL DOMAIN) COMPRISING RESIDUES 191-376, MUTANT WITH ALA 262 REPLACED WITH LEU AND ILE 267 REPLACED WITH MET
Descriptor: GROEL (HSP60 CLASS)
Authors:Buckle, A.M, Fersht, A.R.
Deposit date:1996-12-13
Release date:1997-09-17
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A structural model for GroEL-polypeptide recognition.
Proc.Natl.Acad.Sci.USA, 94, 1997
1BSE
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BU of 1bse by Molmil
CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor: BARNASE
Authors:Buckle, A.M, Henrick, K, Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BSA
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BU of 1bsa by Molmil
CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor: BARNASE
Authors:Buckle, A.M, Henrick, K, Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BSD
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BU of 1bsd by Molmil
CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor: BARNASE
Authors:Buckle, A.M, Henrick, K, Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BSB
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BU of 1bsb by Molmil
CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor: BARNASE
Authors:Buckle, A.M, Henrick, K, Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BRN
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BU of 1brn by Molmil
SUBSITE BINDING IN AN RNASE: STRUCTURE OF A BARNASE-TETRANUCLEOTIDE COMPLEX AT 1.76 ANGSTROMS RESOLUTION
Descriptor: DNA (5'-D(*CP*GP*AP*C)-3'), PROTEIN (BARNASE (E.C.3.1.27.-))
Authors:Buckle, A.M, Fersht, A.R.
Deposit date:1993-11-17
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Subsite binding in an RNase: structure of a barnase-tetranucleotide complex at 1.76-A resolution.
Biochemistry, 33, 1994
1BSC
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BU of 1bsc by Molmil
CRYSTAL STRUCTURAL ANALYSIS OF MUTATIONS IN THE HYDROPHOBIC CORES OF BARNASE
Descriptor: BARNASE
Authors:Buckle, A.M, Henrick, K, Fersht, A.R.
Deposit date:1993-07-19
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BNI
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BU of 1bni by Molmil
BARNASE WILDTYPE STRUCTURE AT PH 6.0
Descriptor: BARNASE
Authors:Cameron, A, Henrick, K, Fersht, A.R, Dodson, G, Buckle, A.M.
Deposit date:1995-05-17
Release date:1995-09-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1BNJ
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BU of 1bnj by Molmil
BARNASE WILDTYPE STRUCTURE AT PH 9.0
Descriptor: BARNASE
Authors:Cameron, A, Henrick, K, Fersht, A.R, Dodson, G, Buckle, A.M.
Deposit date:1995-05-17
Release date:1995-09-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structural analysis of mutations in the hydrophobic cores of barnase.
J.Mol.Biol., 234, 1993
1CIQ
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BU of 1ciq by Molmil
COMPLEX OF TWO FRAGMENTS OF CI2, RESIDUES 1-40 AND 41-64
Descriptor: CHYMOTRYPSIN INHIBITOR 2
Authors:Buckle, A.M, Fersht, A.R.
Deposit date:1995-10-02
Release date:1996-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Towards the complete structural characterization of a protein folding pathway: the structures of the denatured, transition and native states for the association/folding of two complementary fragments of cleaved chymotrypsin inhibitor 2. Direct evidence for a nucleation-condensation mechanism
Structure Fold.Des., 1, 1996
1JON
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BU of 1jon by Molmil
GROEL (HSP60 CLASS) FRAGMENT COMPRISING RESIDUES 191-345
Descriptor: GROEL, HSP60 CLASS
Authors:Buckle, A.M, Fersht, A.R.
Deposit date:1996-05-30
Release date:1997-03-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Chaperone activity and structure of monomeric polypeptide binding domains of GroEL.
Proc.Natl.Acad.Sci.USA, 93, 1996
3G01
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BU of 3g01 by Molmil
Structure of GrC mutant E192R/E193G
Descriptor: Granzyme C
Authors:Buckle, A.M, Kaiserman, D, Whisstock, J.C.
Deposit date:2009-01-27
Release date:2009-03-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of granzyme C reveals an unusual mechanism of protease autoinhibition
Proc.Natl.Acad.Sci.USA, 106, 2009
3FZZ
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BU of 3fzz by Molmil
Structure of GrC
Descriptor: Granzyme C, SULFATE ION
Authors:Buckle, A.M, Kaiserman, D, Whisstock, J.C.
Deposit date:2009-01-27
Release date:2009-03-17
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of granzyme C reveals an unusual mechanism of protease autoinhibition
Proc.Natl.Acad.Sci.USA, 106, 2009
2GPZ
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BU of 2gpz by Molmil
Transthyretin-like protein from Salmonella dublin
Descriptor: SULFATE ION, transthyretin-like protein
Authors:Buckle, A.M, Law, R.H, Whisstock, J.C.
Deposit date:2006-04-19
Release date:2006-05-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Crystal Structure of the Transthyretin-like Protein from Salmonella dublin, a Prokaryote 5-Hydroxyisourate Hydrolase.
J.Mol.Biol., 359, 2006
2H4P
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BU of 2h4p by Molmil
Crystal structure of wildtype MENT in the cleaved conformation
Descriptor: Heterochromatin-associated protein MENT
Authors:Buckle, A.M, McGowan, S, Irving, J.A, Whisstock, J.C.
Deposit date:2006-05-24
Release date:2006-07-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation.
Embo J., 25, 2006
3H7O
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BU of 3h7o by Molmil
Crystal structure of scabies mite inactivated protease paralogue S-I1 (SMIPP-S-I1)
Descriptor: GLYCEROL, Group 3 allergen SMIPP-S Yv6023A04, SULFATE ION
Authors:Buckle, A.M.
Deposit date:2009-04-28
Release date:2009-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural mechanisms of inactivation in scabies mite serine protease paralogues.
J.Mol.Biol., 390, 2009
3H7T
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BU of 3h7t by Molmil
Crystal structure of scabies mite inactivated protease paralogue S-D1 (SMIPP-S-D1)
Descriptor: Group 3 allergen SMIPP-S YvT004A06, ZINC ION
Authors:Buckle, A.M.
Deposit date:2009-04-28
Release date:2009-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural mechanisms of inactivation in scabies mite serine protease paralogues.
J.Mol.Biol., 390, 2009
2DG4
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BU of 2dg4 by Molmil
FK506-binding protein mutant WF59 complexed with Rapamycin
Descriptor: FK506-binding protein 1A, GLYCEROL, RAPAMYCIN IMMUNOSUPPRESSANT DRUG
Authors:Buckle, A.M.
Deposit date:2006-03-08
Release date:2006-04-25
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Energetic and structural analysis of the role of tryptophan 59 in FKBP12
Biochemistry, 42, 2003
2DG3
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BU of 2dg3 by Molmil
Wildtype FK506-binding protein complexed with Rapamycin
Descriptor: FK506-binding protein 1A, GLYCEROL, RAPAMYCIN IMMUNOSUPPRESSANT DRUG
Authors:Buckle, A.M.
Deposit date:2006-03-08
Release date:2006-04-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Energetic and structural analysis of the role of tryptophan 59 in FKBP12
Biochemistry, 42, 2003
2OKK
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BU of 2okk by Molmil
The X-ray crystal structure of the 65kDa isoform of Glutamic Acid Decarboxylase (GAD65)
Descriptor: GAMMA-AMINO-BUTANOIC ACID, GLYCEROL, Glutamate decarboxylase 2
Authors:Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C.
Deposit date:2007-01-17
Release date:2007-03-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
Nat.Struct.Mol.Biol., 14, 2007
2OKJ
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BU of 2okj by Molmil
The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67)
Descriptor: 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID, GAMMA-AMINO-BUTANOIC ACID, Glutamate decarboxylase 1
Authors:Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C.
Deposit date:2007-01-17
Release date:2007-03-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop.
Nat.Struct.Mol.Biol., 14, 2007
6EE5
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BU of 6ee5 by Molmil
Reactive centre loop dynamics and serpin specificity
Descriptor: Conserpin-AATRCL
Authors:Marijanovic, E.M, Porebski, B.T, McGowan, S, Buckle, A.M.
Deposit date:2018-08-13
Release date:2018-08-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Reactive centre loop dynamics and serpin specificity.
Sci Rep, 9, 2019
4U3H
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BU of 4u3h by Molmil
Crystal structure of FN3con
Descriptor: FN3con
Authors:Porebski, B.T, McGowan, S, Buckle, A.M.
Deposit date:2014-07-21
Release date:2015-02-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural and dynamic properties that govern the stability of an engineered fibronectin type III domain.
Protein Eng.Des.Sel., 28, 2015
5J7C
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BU of 5j7c by Molmil
A picomolar affinity FN3 domain in complex with hen egg-white lysozyme
Descriptor: FNfn10-anti-lysozyme (DE0.4.1), Lysozyme C
Authors:Porebski, B.T, Drinkwater, N, McGowan, S, Buckle, A.M.
Deposit date:2016-04-06
Release date:2016-08-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.535 Å)
Cite:Circumventing the stability-function trade-off in an engineered FN3 domain.
Protein Eng.Des.Sel., 2016

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