1YPZ
 
 | | Immune receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | | Authors: | Adams, E.J, Garcia, K.C. | | Deposit date: | 2005-01-31 | | Release date: | 2005-04-12 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22.
Science, 308, 2005
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5HM7
 | | The Intracellular domain of Butyrophilin 3A1 protein | | Descriptor: | BETA-MERCAPTOETHANOL, Butyrophilin subfamily 3 member A1, GLYCEROL, ... | | Authors: | Adams, E.J, Gu, S. | | Deposit date: | 2016-01-15 | | Release date: | 2017-07-26 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Phosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on V gamma 9V delta 2 T cell activation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5IUE
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5KNM
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1R5V
 | | Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T-cell activation | | Descriptor: | H-2 class II histocompatibility antigen, E-K alpha chain, MHC H2-IE-beta, ... | | Authors: | Krogsgaard, M, Prado, N, Adams, E.J, He, X.L, Chow, D.C, Wilson, D.B, Garcia, K.C, Davis, M.M. | | Deposit date: | 2003-10-13 | | Release date: | 2004-02-03 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation.
Mol.Cell, 12, 2003
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1U3H
 | | Crystal structure of mouse TCR 172.10 complexed with MHC class II I-Au molecule at 2.4 A | | Descriptor: | H-2 class II histocompatibility antigen, A-U alpha chain, A-U beta chain, ... | | Authors: | Maynard, J, Petersson, K, Wilson, D.H, Adams, E.J, Blondelle, S.E, Boulanger, M.J, Wilson, D.B, Garcia, K.C. | | Deposit date: | 2004-07-21 | | Release date: | 2005-05-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity
Immunity, 22, 2005
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3OV6
 | | CD1c in complex with MPM (mannosyl-beta1-phosphomycoketide) | | Descriptor: | 1-O-[(S)-hydroxy{[(4S,8S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-beta-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | | Authors: | Scharf, L, Li, N.S, Hawk, A.J, Garzon, D, Zhang, T, Kazen, A.R, Shah, S, Haddadian, E.J, Saghatelian, A, Faraldo-Gomez, J.D, Meredith, S.C, Piccirilli, J.A, Adams, E.J. | | Deposit date: | 2010-09-15 | | Release date: | 2011-01-19 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | The 2.5 A structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation
Immunity, 33, 2010
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4EPU
 | | Ang1 fibrinogen-related domain (FReD) | | Descriptor: | Angiopoietin-1, CALCIUM ION | | Authors: | Yeykal, C.C, Adams, E.J. | | Deposit date: | 2012-04-17 | | Release date: | 2013-04-17 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.098 Å) | | Cite: | Biochemical and structural characterization of the Ang1 fibrinogen-related domain
To be Published
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4EN3
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4F8T
 | | Crystal Structure of the Human BTN3A3 Ectodomain | | Descriptor: | Butyrophilin subfamily 3 member A3 | | Authors: | Palakodeti, A, Sandstrom, A, Sundaresan, L, Harly, C, Nedellec, S, Olive, D, Scotet, E, Bonneville, M, Adams, E.J. | | Deposit date: | 2012-05-17 | | Release date: | 2012-08-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.382 Å) | | Cite: | The molecular basis for modulation of human V(gamma)9V(delta)2 T cell response by CD277/Butryophilin (BTN3A)-specific antibodies
J.Biol.Chem., 287, 2012
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4F9L
 | | Crystal Structure of the Human BTN3A1 Ectodomain in Complex with the 20.1 Single Chain Antibody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 20.1 anti-BTN3A1 antibody fragment, Butyrophilin subfamily 3 member A1 | | Authors: | Palakodeti, A, Sandstrom, A, Sundaresan, L, Harly, C, Nedellec, S, Olive, D, Scotet, E, Bonneville, M, Adams, E.J. | | Deposit date: | 2012-05-18 | | Release date: | 2012-08-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.1404 Å) | | Cite: | The molecular basis for modulation of human V(gamma)9V(delta)2 T cell responses by CD277/Butyrophilin-3 (BTN3A)-specific antibodies
J.Biol.Chem., 287, 2012
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4F80
 | | Crystal Structure of the human BTN3A1 ectodomain | | Descriptor: | Butyrophilin subfamily 3 member A1 | | Authors: | Palakodeti, A, Sandstrom, A, Sundaresan, L, Harly, C, Nedellec, S, Olive, D, Scotet, E, Bonneville, M, Adams, E.J. | | Deposit date: | 2012-05-16 | | Release date: | 2012-08-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.944 Å) | | Cite: | The molecular basis for modulation of human V(gamma)9V(delta)2 T cell responses by CD277/Butyrophilin-3 (BTN3A)-specific antibodies
J.Biol.Chem., 287, 2012
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4F9P
 | | Crystal Structure of the Human BTN3A1 Ectodomain in Complex with the 103.2 Single Chain Antibody | | Descriptor: | 103.2 anti-BTN3A1 antibody fragment, Butyrophilin subfamily 3 member A1 | | Authors: | Palakodeti, A, Sandstrom, A, Sundaresan, L, Harly, C, Nedellec, S, Olive, D, Scotet, E, Bonneville, M, Adams, E.J. | | Deposit date: | 2012-05-19 | | Release date: | 2012-08-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.519 Å) | | Cite: | The molecular basis for modulation of human V(gamma)9V(delta)2 T cell responses by CD277/Butyrophilin-3 (BTN3A)-specific antibodies
J.Biol.Chem., 287, 2012
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4F8Q
 | | Crystal Structure of the Human BTN3A2 Ectodomain | | Descriptor: | Butyrophilin subfamily 3 member A2 | | Authors: | Palakodeti, A, Sandstrom, A, Sundaresan, L, Harly, C, Nedellec, S, Olive, D, Scotet, E, Bonneville, M, Adams, E.J. | | Deposit date: | 2012-05-17 | | Release date: | 2012-08-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.3789 Å) | | Cite: | The molecular basis for modulation of human V(gamma)9V(delta)2 T cell responses by CD277/Butyrophilin-3 (BTN3A)-specific antibodies
J.Biol.Chem., 287, 2012
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6D7G
 | | Structure of 5F3 TCR in complex with HLA-A2/MART-1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MART1 PEPTIDE-BETA-2-MICROGLOBULIN-HLA-A*02 CHIMERA, T-CELL RECEPTOR GAMMA VARIABLE 8,T-CELL RECEPTOR GAMMA-2 CHAIN C REGION, ... | | Authors: | Roy, S, Adams, E.J. | | Deposit date: | 2018-04-24 | | Release date: | 2019-01-23 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Generation and molecular recognition of melanoma-associated antigen-specific human gamma delta T cells.
Sci Immunol, 3, 2018
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3TYF
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3TZV
 | | Crystal structure of an iNKT TCR in complex with CD1d-lysophosphatidylcholine | | Descriptor: | (4R,7R,18E)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ... | | Authors: | Lopez-Sagaseta, J, Adams, E.J. | | Deposit date: | 2011-09-27 | | Release date: | 2012-04-25 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.056 Å) | | Cite: | Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor.
Embo J., 31, 2012
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3U0P
 | | Crystal structure of human CD1d-lysophosphatidylcholine | | Descriptor: | (4R,7R,18E)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ... | | Authors: | Lopez-Sagaseta, J, Sibener, L.V, Adams, E.J. | | Deposit date: | 2011-09-28 | | Release date: | 2012-04-25 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor.
Embo J., 31, 2012
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8G1B
 | | Crystal structure of polyreactive 2G02 human Fab | | Descriptor: | The heavy chain of human 2G02 Fab fragment, The light chain of human 2G02 Fab fragment | | Authors: | Borowska, M.T, Adams, E.J. | | Deposit date: | 2023-02-01 | | Release date: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Biochemical and biophysical characterization of natural polyreactivity in antibodies.
Cell Rep, 42, 2023
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8FZO
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8FZP
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8G1C
 | | Crystal structure of polyreactive 3B03 human Fab | | Descriptor: | Heavy chain of monoreactive 3B03 human Fab fragment, Light chain of monoreactive 3B03 human Fab fragment | | Authors: | Borowska, M.T, Adams, E.J. | | Deposit date: | 2023-02-01 | | Release date: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Biochemical and biophysical characterization of natural polyreactivity in antibodies.
Cell Rep, 42, 2023
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8G19
 | | Crystal structure of monoreactive 4C05 human Fab | | Descriptor: | Heavy chain of anti-influenza human 4C05 Fab fragment, Light chain of anti-influenza human 4C05 Fab fragment | | Authors: | Borowska, M.T, Adams, E.J. | | Deposit date: | 2023-02-01 | | Release date: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Biochemical and biophysical characterization of natural polyreactivity in antibodies.
Cell Rep, 42, 2023
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7KPJ
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4IIQ
 | | Crystal structure of a human MAIT TCR in complex with bovine MR1 | | Descriptor: | Beta-2-microglobulin, MHC class I-related protein, Human Mucosal Associated Invariant T cell receptor alpha chain, ... | | Authors: | Lopez-Sagaseta, J, Adams, E.J. | | Deposit date: | 2012-12-20 | | Release date: | 2013-04-24 | | Last modified: | 2017-08-23 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins.
Proc.Natl.Acad.Sci.USA, 110, 2013
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