Author results

1S5J
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INSIGHT IN DNA REPLICATION: THE CRYSTAL STRUCTURE OF DNA POLYMERASE B1 FROM THE ARCHAEON SULFOLOBUS SOLFATARICUS
Descriptor:DNA polymerase I, SULFATE ION, MAGNESIUM ION
Authors:Savino, C., Federici, L., Nastopoulos, V., Johnson, K.A., Pisani, F.M., Rossi, M., Tsernoglou, D.
Deposit date:2004-01-21
Release date:2004-11-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Insights into DNA replication: the crystal structure of DNA polymerase B1 from the archaeon Sulfolobus solfataricus
Structure, 12, 2004
2JJN
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STRUCTURE OF CLOSED CYTOCHROME P450 ERYK
Descriptor:CYTOCHROME P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Savino, C., Sciara, G., Miele, A.E., Kendrew, S.G., Vallone, B.
Deposit date:2008-04-15
Release date:2009-07-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate.
J.Biol.Chem., 284, 2009
2JJO
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STRUCTURE OF CYTOCHROME P450 ERYK IN COMPLEX WITH ITS NATURAL SUBSTRATE ERD
Descriptor:CYTOCHROME P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, Erythromycin D
Authors:Savino, C., Sciara, G., Miele, A.E., Kendrew, S.G., Vallone, B.
Deposit date:2008-04-15
Release date:2009-07-14
Last modified:2013-02-06
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate.
J.Biol.Chem., 284, 2009
1QI7
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THE CRYSTAL STRUCTURE AT 2.0 A OF SAPORIN SO6, A RIBOSOME INACTIVATING PROTEIN FROM SAPONARIA OFFICINALIS
Descriptor:PROTEIN (N-GLYCOSIDASE), SULFATE ION
Authors:Savino, C., Federici, L., Ippoliti, R., Lendaro, E., Tsernoglou, D.
Deposit date:1999-06-08
Release date:2000-06-05
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of saporin SO6 from Saponaria officinalis and its interaction with the ribosome.
FEBS Lett., 470, 2000
2WIO
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STRUCTURE OF THE HISTIDINE TAGGED, OPEN CYTOCHROME P450 ERYK FROM S. ERYTHRAEA
Descriptor:ERYTHROMYCIN B/D C-12 HYDROXYLASE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Savino, C., Montemiglio, L.C., Sciara, G., Miele, A.E., Kedrew, S.G., Gianni, S., Vallone, B.
Deposit date:2009-05-14
Release date:2009-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Investigating the Structural Plasticity of a Cytochrome P450: Three-Dimensional Structures of P450 Eryk and Binding to its Physiological Substrate.
J.Biol.Chem., 284, 2009
2JJP
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STRUCTURE OF CYTOCHROME P450 ERYK IN COMPLEX WITH INHIBITOR KETOCONAZOLE (KC)
Descriptor:CYTOCHROME P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, 1-ACETYL-4-(4-{[(2S,4R)-2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL]METHOXY}PHENYL)PIPERAZINE, ...
Authors:Savino, C., Sciara, G., Miele, A.E., Kendrew, S.G., Vallone, B.
Deposit date:2008-04-15
Release date:2009-07-14
Last modified:2012-08-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Azole Drugs Trap Cytochrome P450 Eryk in Alternative Conformational States.
Biochemistry, 49, 2010
6I3T
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CRYSTAL STRUCTURE OF MURINE NEUROGLOBIN BOUND TO CO AT 40 K.
Descriptor:Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
Authors:Savino, C., Montemiglio, L.C., Ardiccioni, C., Exertier, C.
Deposit date:2018-11-07
Release date:2019-09-11
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ligand pathways in neuroglobin revealed by low-temperature photodissociation and docking experiments.
Iucrj, 6, 2019
6I40
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CRYSTAL STRUCTURE OF MURINE NEUROGLOBIN BOUND TO CO AT 15K UNDER ILLUMINATION USING OPTICAL FIBER
Descriptor:Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
Authors:Savino, C., Montemiglio, L.C., Ardiccioni, C., Exertier, C., Vallone, B.
Deposit date:2018-11-08
Release date:2019-09-11
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ligand pathways in neuroglobin revealed by low-temperature photodissociation and docking experiments.
Iucrj, 6, 2019
5N9W
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STRUCTURE OF ADENYLATION DOMAIN THR1 INVOLVED IN THE BIOSYNTHESIS OF 4-CHLOROTHREONINE IN STREPTOMYCES SP.OH-5093, APO STRUCTURE
Descriptor:Adenylation domain, ACETATE ION
Authors:Savino, C., Vallone, B., Scaglione, A., Parisi, G., Montemiglio, L.C., Fullone, M.R., Grgurina, I.
Deposit date:2017-02-27
Release date:2017-07-26
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.456 Å)
Cite:Structure of the adenylation domain Thr1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces sp. OH-5093-protein flexibility and molecular bases of substrate specificity.
FEBS J., 284, 2017
5N9X
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STRUCTURE OF ADENYLATION DOMAIN THR1 INVOLVED IN THE BIOSYNTHESIS OF 4-CHLOROTHREONINE IN STREPTOMYCES SP.OH-5093, LIGAND BOUND STRUCTURE
Descriptor:Adenylation domain, THREONINE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Savino, C., Vallone, B., Scaglione, A., Parisi, G., Montemiglio, L.C., Fullone, M.R., Grgurina, I.
Deposit date:2017-02-27
Release date:2017-07-26
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.396 Å)
Cite:Structure of the adenylation domain Thr1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces sp. OH-5093-protein flexibility and molecular bases of substrate specificity.
FEBS J., 284, 2017
2W6V
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STRUCTURE OF HUMAN DEOXY HEMOGLOBIN A IN COMPLEX WITH XENON
Descriptor:HEMOGLOBIN SUBUNIT ALPHA, HEMOGLOBIN SUBUNIT BETA, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Miele, A.E., Draghi, F., Sciara, G., Johnson, K.A., Renzi, F., Vallone, B., Brunori, M., Savino, C.
Deposit date:2008-12-19
Release date:2009-04-28
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Pattern of Cavities in Globins: The Case of Human Hemoglobin.
Biopolymers, 91, 2009
2W6W
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CRYSTAL STRUCTURE OF RECOMBINANT SPERM WHALE MYOGLOBIN UNDER 1ATM OF XENON
Descriptor:MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, XENON, ...
Authors:Miele, A.E., Draghi, F., Renzi, F., Sciara, G., Johnson, K.A., Vallone, B., Brunori, M., Savino, C.
Deposit date:2008-12-19
Release date:2009-04-28
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Pattern of Cavities in Globins: The Case of Human Hemoglobin.
Biopolymers, 91, 2009
2W72
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DEOXYGENATED STRUCTURE OF A DISTAL SITE HEMOGLOBIN MUTANT PLUS XE
Descriptor:HUMAN HEMOGLOBIN A, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:Miele, A.E., Draghi, F., Sciara, G., Johnson, K.A., Renzi, F., Vallone, B., Brunori, M., Savino, C.
Deposit date:2008-12-19
Release date:2009-04-28
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Pattern of Cavities in Globins: The Case of Human Hemoglobin.
Biopolymers, 91, 2009
2XFH
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STRUCTURE OF CYTOCHROME P450 ERYK COCRYSTALLIZED WITH INHIBITOR CLOTRIMAZOLE.
Descriptor:ERYTHROMYCIN B/D C-12 HYDROXYLASE, PROTOPORPHYRIN IX CONTAINING FE, 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE, ...
Authors:Savino, C., Montemiglio, L.C., Gianni, S., Vallone, B.
Deposit date:2010-05-24
Release date:2010-09-29
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Azole Drugs Trap Cytochrome P450 Eryk in Alternative Conformational States.
Biochemistry, 49, 2010
1F63
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CRYSTAL STRUCTURE OF DEOXY SPERM WHALE MYOGLOBIN MUTANT Y(B10)Q(E7)R(E10)
Descriptor:MYOGLOBIN, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE
Authors:Brunori, M., Cutruzzola, F., Savino, C., Travaglini-Allocatelli, C., Vallone, B., Gibson, Q.H.
Deposit date:2000-06-20
Release date:2000-07-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural dynamics of ligand diffusion in the protein matrix: A study on a new myoglobin mutant Y(B10) Q(E7) R(E10).
Biophys.J., 76, 1999
1F65
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CRYSTAL STRUCTURE OF OXY SPERM WHALE MYOGLOBIN MUTANT Y(B10)Q(E7)R(E10)
Descriptor:MYOGLOBIN, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Brunori, M., Cutruzzola, F., Savino, C., Travaglini-Allocatelli, C., Vallone, B., Gibson, Q.H.
Deposit date:2000-06-20
Release date:2000-07-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural dynamics of ligand diffusion in the protein matrix: A study on a new myoglobin mutant Y(B10) Q(E7) R(E10).
Biophys.J., 76, 1999
1HG8
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ENDOPOLYGALACTURONASE FROM THE PHYTOPATHOGENIC FUNGUS FUSARIUM MONILIFORME
Descriptor:ENDOPOLYGALACTURONASE, N-ACETYL-D-GLUCOSAMINE
Authors:Federici, L., Caprari, C., Mattei, B., Savino, C., De Lorenzo, G., Cervone, F., Tsernoglou, D.
Deposit date:2000-12-13
Release date:2001-11-10
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural Requirements of Endopolygalacturonase for the Interaction with Pgip (Polygalacturonase-Inhibiting Protein)
Proc.Natl.Acad.Sci.USA, 98, 2001
1LQ9
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CRYSTAL STRUCTURE OF A MONOOXYGENASE FROM THE GENE ACTVA-ORF6 OF STREPTOMYCES COELICOLOR STRAIN A3(2)
Descriptor:ACTVA-ORF6 MONOOXYGENASE, TETRAETHYLENE GLYCOL
Authors:Sciara, G., Kendrew, S.G., Miele, A.E., Marsh, N.G., Federici, L., Malatesta, F., Schimperna, G., Savino, C., Vallone, B.
Deposit date:2002-05-09
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
EMBO J., 22, 2003
1N5Q
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CRYSTAL STRUCTURE OF A MONOOXYGENASE FROM THE GENE ACTVA-ORF6 OF STREPTOMYCES COELICOLOR IN COMPLEX WITH DEHYDRATED SANCYCLINE
Descriptor:ActaVA-Orf6 monooxygenase, HEXAETHYLENE GLYCOL, 4-DIMETHYLAMINO-1,10,11,12-TETRAHYDROXY-3-OXO-3,4,4A,5-TETRAHYDRO-NAPHTHACENE-2-CARBOXYLIC ACID AMIDE
Authors:Sciara, G., Kendrew, S.G., Miele, A.E., Marsh, N.G., Federici, L., Malatesta, F., Schimperna, G., Savino, C., Vallone, B.
Deposit date:2002-11-07
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22, 2003
1N5S
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CRYSTAL STRUCTURE OF A MONOOXYGENASE FROM THE GENE ACTVA-ORF6 OF STREPTOMYCES COELICOLOR IN COMPLEX WITH THE LIGAND ACETYL DITHRANOL
Descriptor:ActVA-Orf6 monooxygenase, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, (1,8-DIHYDROXY-9-OXO-9,10-DIHYDRO-ANTHRACEN-2-YL)-ACETIC ACID
Authors:Sciara, G., Kendrew, S.G., Miele, A.E., Marsh, N.G., Federici, L., Malatesta, F., Schimperna, G., Savino, C., Vallone, B.
Deposit date:2002-11-07
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22, 2003
1N5T
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CRYSTAL STRUCTURE OF A MONOOXYGENASE FROM THE GENE ACTVA-ORF6 OF STREPTOMYCES COELICOLOR IN COMPLEX WITH THE LIGAND OXIDIZED ACETYL DITHRANOL
Descriptor:ActVA-Orf6 monooxygenase, (1,8-DIHYDROXY-9,10-DIOXO-9,10-DIHYDRO-ANTHRACEN-2-YL)-ACETIC ACID
Authors:Sciara, G., G Kendrew, S., Miele, A.E., Marsh, N.G., Federici, L., Malatesta, F., Schimperna, G., Savino, C., Vallone, B.
Deposit date:2002-11-07
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22, 2003
1N5V
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CRYSTAL STRUCTURE OF A MONOOXYGENASE FROM THE GENE ACTVA-ORF6 OF STREPTOMYCES COELICOLOR IN COMPLEX WITH THE LIGAND NANAOMYCIN D
Descriptor:ActVA-Orf6 monooxygenase, 7-HYDROXY-5-METHYL-3,3A,5,11B-TETRAHYDRO-1,4-DIOXA-CYCLOPENTA[A]ANTHRACENE-2,6,11-TRIONE
Authors:Sciara, G., Kendrew, S.G., Miele, A.E., Marsh, N.G., Federici, L., Malatesta, F., Schimperna, G., Savino, C., Vallone, B.
Deposit date:2002-11-07
Release date:2003-01-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
Embo J., 22, 2003
4MU5
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CRYSTAL STRUCTURE OF MURINE NEUROGLOBIN MUTANT M144W
Descriptor:Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Vallone, B., Avella, G., Savino, C., Ardiccioni, C., Brunori, M.
Deposit date:2013-09-20
Release date:2014-06-18
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Engineering the internal cavity of neuroglobin demonstrates the role of the haem-sliding mechanism.
Acta Crystallogr.,Sect.D, 70, 2014
1DM1
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2.0 A CRYSTAL STRUCTURE OF THE DOUBLE MUTANT H(E7)V, T(E10)R OF MYOGLOBIN FROM APLYSIA LIMACINA
Descriptor:MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Federici, L., Savino, C., Musto, R., Travaglini-Allocatelli, C., Cutruzzola, F., Brunori, M.
Deposit date:1999-12-13
Release date:2000-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Engineering His(E7) affects the control of heme reactivity in Aplysia limacina myoglobin.
Biochem.Biophys.Res.Commun., 269, 2000
4NZI
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CRYSTAL STRUCTURE OF MURINE NEUROGLOBIN MUTANT V140W
Descriptor:Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Avella, G., Savino, C., Vallone, B.
Deposit date:2013-12-12
Release date:2014-06-18
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Engineering the internal cavity of neuroglobin demonstrates the role of the haem-sliding mechanism.
Acta Crystallogr.,Sect.D, 70, 2014
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