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1C1K
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BU of 1c1k by Molmil
BACTERIOPHAGE T4 GENE 59 HELICASE ASSEMBLY PROTEIN
Descriptor: BPT4 GENE 59 HELICASE ASSEMBLY PROTEIN, CHLORIDE ION, IRIDIUM ION
Authors:Mueser, T.C, Jones, C.E, Nossal, N.G, Hyde, C.C.
Deposit date:1999-07-22
Release date:2000-02-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Bacteriophage T4 gene 59 helicase assembly protein binds replication fork DNA. The 1.45 A resolution crystal structure reveals a novel alpha-helical two-domain fold.
J.Mol.Biol., 296, 2000
1TFR
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BU of 1tfr by Molmil
RNASE H FROM BACTERIOPHAGE T4
Descriptor: MAGNESIUM ION, T4 RNASE H
Authors:Mueser, T.C, Nossal, N.G, Hyde, C.C.
Deposit date:1996-04-27
Release date:1996-11-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structure of bacteriophage T4 RNase H, a 5' to 3' RNA-DNA and DNA-DNA exonuclease with sequence similarity to the RAD2 family of eukaryotic proteins.
Cell(Cambridge,Mass.), 85, 1996
1G0A
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BU of 1g0a by Molmil
CARBONMONOXY LIGANDED BOVINE HEMOGLOBIN PH 8.5
Descriptor: CARBON MONOXIDE, HEMOGLOBIN ALPHA CHAIN, HEMOGLOBIN BETA CHAIN, ...
Authors:Mueser, T.C, Rogers, P.H, Arnone, A.
Deposit date:2000-10-05
Release date:2000-12-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Interface sliding as illustrated by the multiple quaternary structures of liganded hemoglobin.
Biochemistry, 39, 2000
1G09
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BU of 1g09 by Molmil
CARBONMONOXY LIGANDED BOVINE HEMOGLOBIN PH 7.2
Descriptor: CARBON MONOXIDE, HEMOGLOBIN ALPHA CHAIN, HEMOGLOBIN BETA CHAIN, ...
Authors:Mueser, T.C, Rogers, P.H, Arnone, A.
Deposit date:2000-10-05
Release date:2000-12-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Interface sliding as illustrated by the multiple quaternary structures of liganded hemoglobin.
Biochemistry, 39, 2000
1G0B
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BU of 1g0b by Molmil
CARBONMONOXY LIGANDED EQUINE HEMOGLOBIN PH 8.5
Descriptor: CARBON MONOXIDE, HEMOGLOBIN ALPHA CHAIN, HEMOGLOBIN BETA CHAIN, ...
Authors:Mueser, T.C, Rogers, P.H, Arnone, A.
Deposit date:2000-10-05
Release date:2000-12-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Interface sliding as illustrated by the multiple quaternary structures of liganded hemoglobin.
Biochemistry, 39, 2000
1G08
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BU of 1g08 by Molmil
CARBONMONOXY LIGANDED BOVINE HEMOGLOBIN PH 5.0
Descriptor: CARBON MONOXIDE, HEMOGLOBIN ALPHA CHAIN, HEMOGLOBIN BETA CHAIN, ...
Authors:Mueser, T.C, Rogers, P.H, Arnone, A.
Deposit date:2000-10-05
Release date:2000-12-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Interface sliding as illustrated by the multiple quaternary structures of liganded hemoglobin.
Biochemistry, 39, 2000
5TOQ
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BU of 5toq by Molmil
High resolution crystal structure of AAT
Descriptor: Aspartate aminotransferase, cytoplasmic
Authors:Mueser, T.C, Dajnowicz, S, Kovalevsky, A.
Deposit date:2016-10-18
Release date:2017-03-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Direct evidence that an extended hydrogen-bonding network influences activation of pyridoxal 5'-phosphate in aspartate aminotransferase.
J. Biol. Chem., 292, 2017
5TON
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BU of 5ton by Molmil
Crystal structure of AAT H143L mutant
Descriptor: Aspartate aminotransferase, cytoplasmic
Authors:Mueser, T.C, Dajnowicz, S, Kovalevsky, A.
Deposit date:2016-10-18
Release date:2017-03-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Direct evidence that an extended hydrogen-bonding network influences activation of pyridoxal 5'-phosphate in aspartate aminotransferase.
J. Biol. Chem., 292, 2017
5TOR
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BU of 5tor by Molmil
Crystal structure of AAT D222T mutant
Descriptor: Aspartate aminotransferase, cytoplasmic
Authors:Mueser, T.C, Dajnowicz, S, Kovalevsky, A.
Deposit date:2016-10-18
Release date:2017-03-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Direct evidence that an extended hydrogen-bonding network influences activation of pyridoxal 5'-phosphate in aspartate aminotransferase.
J. Biol. Chem., 292, 2017
5TOT
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BU of 5tot by Molmil
Crystal structure of AAT H143L:H189L double mutant
Descriptor: Aspartate aminotransferase, cytoplasmic
Authors:Mueser, T.C, Dajnowicz, S, Kovalevsky, A.
Deposit date:2016-10-18
Release date:2017-03-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Direct evidence that an extended hydrogen-bonding network influences activation of pyridoxal 5'-phosphate in aspartate aminotransferase.
J. Biol. Chem., 292, 2017
3RDE
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BU of 3rde by Molmil
Crystal structure of the catalytic domain of porcine leukocyte 12-lipoxygenase
Descriptor: 3-{4-[(tridec-2-yn-1-yloxy)methyl]phenyl}propanoic acid, Arachidonate 12-lipoxygenase, 12S-type, ...
Authors:Funk, M.O, Xu, S, Marnett, L.J, Mueser, T.C.
Deposit date:2011-04-01
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.892 Å)
Cite:Crystal structure of 12-lipoxygenase catalytic-domain-inhibitor complex identifies a substrate-binding channel for catalysis.
Structure, 20, 2012
5C6E
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BU of 5c6e by Molmil
Joint X-ray/neutron structure of equine cyanomet hemoglobin in R state
Descriptor: CYANIDE ION, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
Authors:Dajnowicz, S, Sean, S, Hanson, B.L, Fisher, S.Z, Langan, P, Kovalevsky, A.Y, Mueser, T.C.
Deposit date:2015-06-22
Release date:2016-06-22
Last modified:2024-03-06
Method:NEUTRON DIFFRACTION (1.7 Å), X-RAY DIFFRACTION
Cite:Visualizing the Bohr effect in hemoglobin: neutron structure of equine cyanomethemoglobin in the R state and comparison with human deoxyhemoglobin in the T state.
Acta Crystallogr D Struct Biol, 72, 2016
7TUR
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BU of 7tur by Molmil
Joint X-ray/neutron structure of aspastate aminotransferase (AAT) in complex with pyridoxamine 5'-phosphate (PMP)
Descriptor: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aspartate aminotransferase, ...
Authors:Drago, V.N, Kovalevsky, A.Y, Dajnowicz, S, Mueser, T.C.
Deposit date:2022-02-03
Release date:2022-09-28
Last modified:2023-10-25
Method:NEUTRON DIFFRACTION (1.7 Å), X-RAY DIFFRACTION
Cite:An N⋯H⋯N low-barrier hydrogen bond preorganizes the catalytic site of aspartate aminotransferase to facilitate the second half-reaction.
Chem Sci, 13, 2022
2IHN
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BU of 2ihn by Molmil
Co-crystal of Bacteriophage T4 RNase H with a fork DNA substrate
Descriptor: 5'-D(*CP*TP*AP*AP*CP*TP*TP*TP*GP*AP*GP*GP*CP*AP*GP*AP*CP*C)-3', 5'-D(*GP*GP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*TP*AP*GP*TP*CP*AP*A)-3', Ribonuclease H
Authors:Devos, J.M, Mueser, T.C.
Deposit date:2006-09-26
Release date:2007-08-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how FEN-1 family nucleases bind their substrates.
J.Biol.Chem., 282, 2007
1QBZ
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BU of 1qbz by Molmil
THE CRYSTAL STRUCTURE OF THE SIV GP41 ECTODOMAIN AT 1.47 A
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, MERCURY (II) ION, ...
Authors:Yang, Z.-N, Mueser, T.C, Kaufman, J, Stahl, S.J, Wingfield, P.T, Hyde, C.C.
Deposit date:1999-04-28
Release date:1999-05-17
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:The crystal structure of the SIV gp41 ectodomain at 1.47 A resolution.
J.Struct.Biol., 126, 1999
8EZC
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BU of 8ezc by Molmil
X-ray crystal structure of salmonella typhimurium Tryptophan synthase internal aldimine
Descriptor: SODIUM ION, Tryptophan synthase alpha chain, Tryptophan synthase beta chain
Authors:Drago, V.N, Mueser, T.C.
Deposit date:2022-10-31
Release date:2024-02-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Neutron diffraction from a microgravity-grown crystal reveals the active site hydrogens of the internal aldimine form of tryptophan synthase
Cell Rep Phys Sci, 5, 2024
8EYP
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BU of 8eyp by Molmil
Joint X-ray/neutron structure of Salmonella typhimurium tryptophan synthase internal aldimine from microgravity-grown crystal
Descriptor: SODIUM ION, Tryptophan synthase alpha chain, Tryptophan synthase beta chain
Authors:Drago, V.N, Kovalevsky, A, Blakeley, M.P, Forsyth, V.T, Mueser, T.C.
Deposit date:2022-10-28
Release date:2024-02-14
Last modified:2024-02-28
Method:NEUTRON DIFFRACTION (1.8 Å), X-RAY DIFFRACTION
Cite:Neutron diffraction from a microgravity-grown crystal reveals the active site hydrogens of the internal aldimine form of tryptophan synthase
Cell Rep Phys Sci, 5, 2024
8EYS
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BU of 8eys by Molmil
X-ray crystal structure of salmonella typhimurium Tryptophan synthase internal aldimine at pH 5.0
Descriptor: Tryptophan synthase alpha chain, Tryptophan synthase beta chain
Authors:Drago, V.N, Kovalevsky, A.Y, Mueser, T.C.
Deposit date:2022-10-28
Release date:2024-02-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Neutron diffraction from a microgravity-grown crystal reveals the active site hydrogens of the internal aldimine form of tryptophan synthase
Cell Rep Phys Sci, 5, 2024
1C0M
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BU of 1c0m by Molmil
CRYSTAL STRUCTURE OF RSV TWO-DOMAIN INTEGRASE
Descriptor: PROTEIN (INTEGRASE)
Authors:Yang, Z.-N, Mueser, T.C, Bushman, F.D, Hyde, C.C.
Deposit date:1999-07-16
Release date:2000-03-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase.
J.Mol.Biol., 296, 2000
1C1A
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BU of 1c1a by Molmil
CRYSTAL STRUCTURE OF RSV TWO-DOMAIN INTEGRASE
Descriptor: RSV INTEGRASE
Authors:Yang, Z.-N, Mueser, T.C, Bushman, F.D, Hyde, C.C.
Deposit date:1999-07-21
Release date:2000-03-01
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase.
J.Mol.Biol., 296, 2000
7MT4
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BU of 7mt4 by Molmil
Crystal structure of tryptophan Synthase in complex with F9, NH4+, pH7.8 - alpha aminoacrylate form - E(A-A)
Descriptor: 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, AMMONIUM ION, ...
Authors:Drago, V, Hilario, E, Dunn, M.F, Mueser, T.C, Mueller, L.J.
Deposit date:2021-05-12
Release date:2021-12-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Imaging active site chemistry and protonation states: NMR crystallography of the tryptophan synthase alpha-aminoacrylate intermediate.
Proc.Natl.Acad.Sci.USA, 119, 2022
7MT6
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BU of 7mt6 by Molmil
Crystal structure of tryptophan synthase in complex with F9, Cs+, benzimidazole, pH7.8 - alpha aminoacrylate form - E(A-A)(BZI)
Descriptor: 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, BENZIMIDAZOLE, ...
Authors:Drago, V, Hilario, E, Dunn, M.F, Mueser, T.C, Mueller, L.J.
Deposit date:2021-05-12
Release date:2021-12-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Imaging active site chemistry and protonation states: NMR crystallography of the tryptophan synthase alpha-aminoacrylate intermediate.
Proc.Natl.Acad.Sci.USA, 119, 2022
7MT5
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BU of 7mt5 by Molmil
Crystal structure of tryptophan synthase in complex with F9, Cs+, pH7.8 - alpha aminoacrylate form - E(A-A)
Descriptor: 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, CESIUM ION, ...
Authors:Drago, V, Hilario, E, Dunn, M.F, Mueser, T.C, Mueller, L.J.
Deposit date:2021-05-12
Release date:2021-12-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Imaging active site chemistry and protonation states: NMR crystallography of the tryptophan synthase alpha-aminoacrylate intermediate.
Proc.Natl.Acad.Sci.USA, 119, 2022
3H8W
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BU of 3h8w by Molmil
Structure of D132N T4 RNase H in the presence of divalent magnesium
Descriptor: Ribonuclease H
Authors:Tomanicek, S.J, Mueser, T.C.
Deposit date:2009-04-29
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Additional Order Appears in the Absence of Metals in a FEN-1 protein: Structural Analysis of Magnesium Binding to Bacteriophage T4 RNaseH
TO BE PUBLISHED
3H7I
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BU of 3h7i by Molmil
Structure of the metal-free D132N T4 RNase H
Descriptor: Ribonuclease H, SULFATE ION
Authors:Tomanicek, S.J, Mueser, T.C.
Deposit date:2009-04-27
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Additional Order Appears in the Absence of Metals in a FEN-1 protein: Structural Analysis of Magnesium Binding to Bacteriophage T4 RNaseH
To be Published

 

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