Author results

6JU2
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO CRNA PROMOTER IN CLASS 1
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-04-12
Release date:2019-06-12
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 2019
6JU3
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STRUCTURE OF INFLUENZA D VIRUS POLYMERASE BOUND TO CRNA PROMOTER IN CLASS 2
Descriptor:Polymerase 3, RNA-directed RNA polymerase catalytic subunit, Polymerase PB2, ...
Authors:Peng, Q., Peng, R., Qi, J., Gao, G.F., Shi, Y.
Deposit date:2019-04-12
Release date:2019-06-12
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 2019
6R47
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THE STRUCTURE OF PISTOL RIBOZYME BOUND TO MAGNESIUM
Descriptor:RNA (50-MER), RNA, MAGNESIUM ION
Authors:Lilley, D.M.J., Wilson, T.M., Liu, Y.
Deposit date:2019-03-22
Release date:2019-07-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Comparison of the Structures and Mechanisms of the Pistol and Hammerhead Ribozymes.
J.Am.Chem.Soc., 141, 2019
6O8B
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CRYSTAL STRUCTURE OF STING CTD IN COMPLEX WITH TBK1
Descriptor:Stimulator of interferon genes protein, Serine/threonine-protein kinase TBK1, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide
Authors:Li, P., Zhao, B., Du, F.
Deposit date:2019-03-09
Release date:2019-05-22
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature, 569, 2019
6O8C
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CRYSTAL STRUCTURE OF STING CTT IN COMPLEX WITH TBK1
Descriptor:Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide
Authors:Li, P., Zhao, B., Du, F.
Deposit date:2019-03-09
Release date:2019-05-22
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature, 569, 2019
6O3N
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CROSS-ALPHA AMYLOID-LIKE STRUCTURE ALPHAAMA
Descriptor:Cross-alpha Amyloid-like Structure alphaAmA
Authors:Zhang, S.-Q., Liu, L., DeGrado, W.F.
Deposit date:2019-02-26
Release date:2019-03-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Designed peptides that assemble into cross-alpha amyloid-like structures
Nat. Chem. Biol., 14, 2018
6NT2
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TYPE 1 PRMT IN COMPLEX WITH THE INHIBITOR GSK3368715
Descriptor:Protein arginine N-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, N~1~-({5-[4,4-bis(ethoxymethyl)cyclohexyl]-1H-pyrazol-4-yl}methyl)-N~1~,N~2~-dimethylethane-1,2-diamine, ...
Authors:Concha, N.O.
Deposit date:2019-01-28
Release date:2019-07-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss.
Cancer Cell, 2019
6NQD
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CRYO-EM STRUCTURE OF T/F100 SOSIP.664 HIV-1 ENV TRIMER IN COMPLEX WITH 8ANC195 FAB
Descriptor:T/F100 Env gp120, T/F100 Env gp41, 8ANC195 G52K5 heavy chain, ...
Authors:Fang, Q., Rossmann, M.G.
Deposit date:2019-01-21
Release date:2019-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:A sequestered fusion peptide in the structure of an HIV-1 transmitted founder envelope trimer.
Nat Commun, 10, 2019
6J7J
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA EARP
Descriptor:Pseudomonas aeruginosa Earp, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:He, C., Li, F.
Deposit date:2019-01-18
Release date:2019-05-15
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Complex Structure ofPseudomonas aeruginosaArginine Rhamnosyltransferase EarP with Its Acceptor Elongation Factor P.
J.Bacteriol., 201, 2019
6J7K
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA EARP IN COMPLEX WITH TDP-RHA
Descriptor:Pseudomonas aeruginosa Earp, 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:He, C., Li, F.
Deposit date:2019-01-18
Release date:2019-05-15
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Complex Structure ofPseudomonas aeruginosaArginine Rhamnosyltransferase EarP with Its Acceptor Elongation Factor P.
J.Bacteriol., 201, 2019
6J7L
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA EARP IN COMPLEX WITH TDP
Descriptor:Pseudomonas aeruginosa Earp, THYMIDINE-5'-DIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:He, C., Li, F.
Deposit date:2019-01-18
Release date:2019-05-15
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Complex Structure ofPseudomonas aeruginosaArginine Rhamnosyltransferase EarP with Its Acceptor Elongation Factor P.
J.Bacteriol., 201, 2019
6J7M
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COMPLEX STRUCTURE OF THE PSEUDOMONAS AERUGINOSA RHAMNOSYLTRANSFERASE EARP WITH THE ACCEPTOR ELONGATION FACTOR EF-P
Descriptor:Earp, Elongation factor P, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:He, C., Li, F.
Deposit date:2019-01-18
Release date:2019-05-15
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Complex Structure ofPseudomonas aeruginosaArginine Rhamnosyltransferase EarP with Its Acceptor Elongation Factor P.
J.Bacteriol., 201, 2019
6NN3
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STRUCTURE OF PARVOVIRUS B19 DECORATED WITH FAB MOLECULES FROM A HUMAN ANTIBODY
Descriptor:VP2 of B19 parvovirus, Fab monoclonal antibody 860-55D, heavy chain, ...
Authors:Rossmann, M.G., Sun, Y., Klose, T., Liu, Y.
Deposit date:2019-01-14
Release date:2019-02-13
Last modified:2019-05-01
Method:ELECTRON MICROSCOPY (3.22 Å)
Cite:Structure of Parvovirus B19 Decorated by Fabs from a Human Antibody.
J. Virol., 93, 2019
6J0Z
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CRYSTAL STRUCTURE OF ALPK
Descriptor:Putative angucycline-like polyketide oxygenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Wang, W., Liu, Y., Liang, H.
Deposit date:2018-12-27
Release date:2019-03-06
Method:X-RAY DIFFRACTION (2.889 Å)
Cite:Crystal structure of AlpK: An essential monooxygenase involved in the biosynthesis of kinamycin
Biochem. Biophys. Res. Commun., 510, 2019
6NHV
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SINGLE PARTICLE RECONSTRUCTION OF DARPIN AND ITS BOUND GFP ON A SYMMETRIC SCAFFOLD
Descriptor:superfolder GFP, DARP14 - Subunit B, Subunit A-DARPin
Authors:Liu, Y., Huynh, D., Yeates, T.O.
Deposit date:2018-12-24
Release date:2019-05-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A 3.8 angstrom resolution cryo-EM structure of a small protein bound to an imaging scaffold.
Nat Commun, 10, 2019
6NHT
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SINGLE PARTICLE RECONSTRUCTION OF THE SYMMETRIC CORE AN ENGINEERED PROTEIN SCAFFOLD
Descriptor:DARP14 - Subunit A with DARPin, DARP14 - Subunit B
Authors:Liu, Y., Huynh, D., Yeates, T.O.
Deposit date:2018-12-23
Release date:2019-05-08
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:A 3.8 angstrom resolution cryo-EM structure of a small protein bound to an imaging scaffold.
Nat Commun, 10, 2019
6IXM
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CRYSTAL STRUCTURE OF THE KETONE REDUCTASE CHKRED20 FROM THE GENOME OF CHRYSEOBACTERIUM SP. CA49 COMPLEXED WITH NAD
Descriptor:Short-chain dehydrogenase reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Zhao, F.J., Jin, Y., Liu, Z.C., Wang, G.G., Wu, Z.L.
Deposit date:2018-12-11
Release date:2019-04-03
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structure-guided engineering of ChKRED20 from Chryseobacterium sp. CA49 for asymmetric reduction of aryl ketoesters.
Enzyme Microb. Technol., 125, 2019
6NCL
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NEAR-ATOMIC STRUCTURE OF ICOSAHEDRALLY AVERAGED PBCV-1 CAPSID
Descriptor:P14, P9, P10, ...
Authors:Fang, Q., Rossmann, M.G.
Deposit date:2018-12-11
Release date:2019-01-30
Last modified:2019-02-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Near-atomic structure of a giant virus.
Nat Commun, 10, 2019
6IQD
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CRYSTAL STRUCTURE OF ALCOHOL DEHYDROGENASE FROM GEOBACILLUS STEAROTHERMOPHILUS
Descriptor:Alcohol dehydrogenase, ZINC ION
Authors:Xue, S., Feng, Y., Guo, X., Zhao, Z.
Deposit date:2018-11-07
Release date:2019-06-05
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Characterization of the substrate scope of an alcohol dehydrogenase commonly used as methanol dehydrogenase.
Bioorg.Med.Chem.Lett., 29, 2019
6MZC
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HUMAN TFIID BC CORE
Descriptor:Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 4, Transcription initiation factor TFIID subunit 5, ...
Authors:Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZD
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HUMAN TFIID LOBE A CANONICAL
Descriptor:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 3, Transcription initiation factor TFIID subunit 4, ...
Authors:Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZI
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CRYOEM STRUCTURE OF HUMAN ENTEROVIRUS D68 EXPANDED 1 PARTICLE (PH 6.5, 4 DEGREES CELSIUS, 3 MIN)
Descriptor:viral protein 1, viral protein 3, viral protein 2, ...
Authors:Liu, Y., Rossmann, M.G.
Deposit date:2018-11-05
Release date:2018-12-19
Last modified:2019-01-09
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6MZL
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HUMAN TFIID CANONICAL STATE
Descriptor:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, Transcription initiation factor TFIID subunit 3, ...
Authors:Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (23 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6MZM
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HUMAN TFIID BOUND TO PROMOTER DNA AND TFIIA
Descriptor:Transcription initiation factor TFIID subunit 1, TAF1, Transcription initiation factor TFIID subunit 2, ...
Authors:Patel, A.B., Louder, R.K., Greber, B.J., Grunberg, S., Luo, J., Fang, J., Liu, Y., Ranish, J., Hahn, S., Nogales, E.
Deposit date:2018-11-05
Release date:2018-11-28
Last modified:2019-01-02
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
6IH2
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CRYSTAL STRUCTURE OF PHOSPHITE DEHYDROGENASE FROM RALSTONIA SP. 4506
Descriptor:Phosphite dehydrogenase
Authors:Song, X., Zhao, Z., Liu, Y., Feng, Y.
Deposit date:2018-09-28
Release date:2019-03-13
Method:X-RAY DIFFRACTION (2.048 Å)
Cite:Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor
Acs Catalysis, 9, 2019