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8R61
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BU of 8r61 by Molmil
Structure of IgE delta epsilon 3-4 in complex with a kappa binding nanobody
Descriptor: HMM5 IgE light chain, Immunoglobulin E VH-Ceps1-Ceps1, kappa binding nanobody
Authors:Andersen, G.R, Gandini, R.
Deposit date:2023-11-20
Release date:2023-11-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of IgE delta epsilon 3-4 in complex with a kappa binding nanobody
To Be Published
1IJE
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BU of 1ije by Molmil
Nucleotide Exchange Intermediates in the eEF1A-eEF1Ba Complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, elongation factor 1-alpha, elongation factor 1-beta
Authors:Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J.
Deposit date:2001-04-26
Release date:2001-05-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1IJF
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BU of 1ijf by Molmil
Nucleotide exchange mechanisms in the eEF1A-eEF1Ba complex
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, elongation factor 1-alpha, ...
Authors:Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J.
Deposit date:2001-04-26
Release date:2001-05-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
1G7C
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BU of 1g7c by Molmil
YEAST EEF1A:EEF1BA IN COMPLEX WITH GDPNP
Descriptor: ELONGATION FACTOR 1-ALPHA, ELONGATION FACTOR 1-BETA, GUANOSINE-5'-MONOPHOSPHATE
Authors:Andersen, G.R, Valente, L, Pedersen, L, Kinzy, T.G, Nyborg, J.
Deposit date:2000-11-10
Release date:2000-12-06
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of nucleotide exchange intermediates in the eEF1A-eEF1Balpha complex.
Nat.Struct.Biol., 8, 2001
8C1B
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BU of 8c1b by Molmil
Focused map for structure of IgE bound to the ectodomain of FceRIa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, Immunoglobulin heavy constant epsilon, ...
Authors:Andersen, G.R, Jensen, R.K.
Deposit date:2022-12-20
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of IgE bound to the ectodomain of FceRIa
To Be Published
8C1C
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BU of 8c1c by Molmil
Structure of IgE bound to the ectodomain of FceRIa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, ...
Authors:Andersen, G.R, Jensen, R.K.
Deposit date:2022-12-20
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of IgE bound to the ectodomain of FceRIa
To Be Published
1D2E
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BU of 1d2e by Molmil
CRYSTAL STRUCTURE OF MITOCHONDRIAL EF-TU IN COMPLEX WITH GDP
Descriptor: ELONGATION FACTOR TU (EF-TU), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Andersen, G.R, Thirup, S, Spremulli, L.L, Nyborg, J.
Deposit date:1999-09-23
Release date:1999-09-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:High resolution crystal structure of bovine mitochondrial EF-Tu in complex with GDP.
J.Mol.Biol., 297, 2000
1F60
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BU of 1f60 by Molmil
CRYSTAL STRUCTURE OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
Descriptor: ELONGATION FACTOR EEF1A, ELONGATION FACTOR EEF1BA
Authors:Andersen, G.R, Pedersen, L, Valente, L, Kinzy, T.G, Nyborg, J.
Deposit date:2000-06-19
Release date:2000-07-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural basis for nucleotide exchange and competition with tRNA in the yeast elongation factor complex eEF1A:eEF1Balpha.
Mol.Cell, 6, 2000
6XZU
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BU of 6xzu by Molmil
Complex of C-terminal domain of murine complement C3b with the hC3Nb3 nanobody
Descriptor: Complement C3, nanobody hC3Nb1
Authors:Andersen, G.R, Pedersen, H.
Deposit date:2020-02-05
Release date:2020-08-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity.
J Immunol., 205, 2020
8COE
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BU of 8coe by Molmil
complement C5 in complex with the LCP0195 nanobody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5 alpha chain, Complement C5 beta chain, ...
Authors:Andersen, G.R, Pedersen, D.V.
Deposit date:2023-02-28
Release date:2024-01-03
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Characterization of the bispecific VHH antibody gefurulimab (ALXN1720) targeting complement component 5, and designed for low volume subcutaneous administration.
Mol.Immunol., 165, 2023
8CEM
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BU of 8cem by Molmil
Structure of bovine native C3, re-refinement
Descriptor: Complement C3 alpha chain, Complement C3 beta chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Andersen, G.R, Fredslund, F.
Deposit date:2023-02-02
Release date:2023-04-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of bovine complement component 3 reveals the basis for thioester function.
J Mol Biol, 361, 2006
3EX7
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BU of 3ex7 by Molmil
The crystal structure of EJC in its transition state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Eukaryotic initiation factor 4A-III, ...
Authors:Andersen, G.R, Nielsen, K.H.
Deposit date:2008-10-16
Release date:2008-12-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Mechanism of ATP turnover inhibition in the EJC
Rna, 15, 2009
5I8O
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BU of 5i8o by Molmil
HMM5 Fab in complex with disaccharide
Descriptor: HMM5 antibody heavy chain, HMM5 antibody light chain, alpha-L-fucopyranose-(1-3)-methyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside
Authors:Andersen, G.R, Tjerrild, L.M, Spillner, E.
Deposit date:2016-02-19
Release date:2016-03-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of HMM5 Fab with a bound disaccharide
To be published
5I8K
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BU of 5i8k by Molmil
HHH1 Fab fragment
Descriptor: HHH1 Fab Heavy chain, HHH1 Fab Light chain
Authors:Andersen, G.R, Spillner, E.
Deposit date:2016-02-19
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.771 Å)
Cite:HHH1 Fab fragment
To be published
7Q1Y
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BU of 7q1y by Molmil
X-ray structure of human A2ML1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin-like protein 1, ...
Authors:Andersen, G.R, Zarantonello, A, Enghild, J.J, Nielsen, N.S.
Deposit date:2021-10-22
Release date:2022-04-20
Last modified:2022-11-02
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Cryo-EM structures of human A2ML1 elucidate the protease-inhibitory mechanism of the A2M family.
Nat Commun, 13, 2022
7ASC
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BU of 7asc by Molmil
TGFBIp mutant A546T
Descriptor: Transforming growth factor-beta-induced protein ig-h3
Authors:Andersen, G.R, Nielsen, N.S, Gadeberg, T.A.F.
Deposit date:2020-10-27
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.8 Å)
Cite:Mutation-induced dimerization of transforming growth factor-beta-induced protein may drive protein aggregation in granular corneal dystrophy.
J.Biol.Chem., 297, 2021
7AS7
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BU of 7as7 by Molmil
Crystal structure of the GCD-associated TGFBIp mutant R124H
Descriptor: Transforming growth factor-beta-induced protein ig-h3
Authors:Andersen, G.R, Gadeberg, T.A.F, Nielsen, N.S, Enghild, J.J.
Deposit date:2020-10-27
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mutation-induced dimerization of transforming growth factor-beta-induced protein may drive protein aggregation in granular corneal dystrophy.
J.Biol.Chem., 297, 2021
5O8W
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BU of 5o8w by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA
Descriptor: Elongation factor 1-alpha, Elongation factor 1-beta, GLUTAMINE, ...
Authors:Wirth, C, Andersen, G.R, Hunte, C.
Deposit date:2017-06-14
Release date:2017-08-23
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A.
J. Biol. Chem., 292, 2017
4WB3
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BU of 4wb3 by Molmil
Crystal structure of the mirror-image L-RNA/L-DNA aptamer NOX-D20 in complex with mouse C5a-desArg complement anaphylatoxin
Descriptor: ACETATE ION, CALCIUM ION, Complement C5, ...
Authors:Yatime, L, Maasch, C, Hoehlig, K, Klussmann, S, Vater, A, Andersen, G.R.
Deposit date:2014-09-02
Release date:2015-05-06
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer.
Nat Commun, 6, 2015
4WB2
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BU of 4wb2 by Molmil
Crystal structure of the mirror-image L-RNA/L-DNA aptamer NOX-D20 in complex with mouse C5a complement anaphylatoxin
Descriptor: ACETATE ION, CALCIUM ION, Complement C5, ...
Authors:Yatime, L, Maasch, C, Hoehlig, K, Klussmann, S, Vater, A, Andersen, G.R.
Deposit date:2014-09-02
Release date:2015-05-06
Last modified:2023-07-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer.
Nat Commun, 6, 2015
3KQ4
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BU of 3kq4 by Molmil
Structure of Intrinsic Factor-Cobalamin bound to its receptor Cubilin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Andersen, C.B.F, Madsen, M, Moestrup, S.K, Andersen, G.R.
Deposit date:2009-11-17
Release date:2010-03-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for receptor recognition of vitamin-B(12)-intrinsic factor complexes.
Nature, 464, 2010
4F4O
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BU of 4f4o by Molmil
Structure of the Haptoglobin-Haemoglobin Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Haptoglobin, ...
Authors:Andersen, C.B.F, Torvund-Jensen, M, Nielsen, M.J, Oliveira, C.L.P, Hersleth, H.P, Andersen, N.H, Pedersen, J.S, Andersen, G.R, Moestrup, S.K.
Deposit date:2012-05-11
Release date:2012-08-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the haptoglobin-haemoglobin complex.
Nature, 489, 2012
8OQ3
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BU of 8oq3 by Molmil
Structure of methylamine treated human complement C3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gadeberg, T.A.F, Andersen, G.R.
Deposit date:2023-04-11
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of methylamine treated human complement C3
To Be Published
3PRX
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BU of 3prx by Molmil
Structure of Complement C5 in Complex with CVF and SSL7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ...
Authors:Laursen, N.S, Andersen, G.R, Sottrup-Jensen, L, Andersen, K.R, Spillner, E, Braren, I.
Deposit date:2010-11-30
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
3PVM
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BU of 3pvm by Molmil
Structure of Complement C5 in Complex with CVF
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, Complement C5
Authors:Laursen, N.S, Andersen, K.R, Braren, I, Sottrup-Jensen, L, Spillner, E, Andersen, G.R.
Deposit date:2010-12-07
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011

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