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8JOZ
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BU of 8joz by Molmil
Crystal structure of CmoM from E. coli complexed with sinefungin and cellularly expressed tRNA Ser
Descriptor: MAGNESIUM ION, SINEFUNGIN, tRNA 5-carboxymethoxyuridine methyltransferase, ...
Authors:Yoo, J, Kim, J.
Deposit date:2023-06-09
Release date:2023-08-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural basis for the selective methylation of 5-carboxymethoxyuridine in tRNA modification.
Nucleic Acids Res., 51, 2023
6BW6
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BU of 6bw6 by Molmil
Human GPT (DPAGT1) H129 variant in complex with tunicamycin
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Tunicamycin, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
Authors:Yoo, J, Kuk, A.C.Y, Mashalidis, E.H, Lee, S.-Y.
Deposit date:2017-12-14
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation.
Nat. Struct. Mol. Biol., 25, 2018
6DT0
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BU of 6dt0 by Molmil
Cryo-EM structure of a mitochondrial calcium uniporter
Descriptor: CALCIUM ION, Mitochondrial calcium uniporter
Authors:Yoo, J, Wu, M, Yin, Y, Herzik, M.A.J, Lander, G.C, Lee, S.-Y.
Deposit date:2018-06-14
Release date:2018-07-11
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of a mitochondrial calcium uniporter.
Science, 361, 2018
6BW5
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BU of 6bw5 by Molmil
Human GPT (DPAGT1) in complex with tunicamycin
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Tunicamycin, UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
Authors:Yoo, J, Kuk, A.C.Y, Mashalidis, E.H, Lee, S.-Y.
Deposit date:2017-12-14
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:GlcNAc-1-P-transferase-tunicamycin complex structure reveals basis for inhibition of N-glycosylation.
Nat. Struct. Mol. Biol., 25, 2018
4ZG0
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BU of 4zg0 by Molmil
Crystal structure of Mouse Syndesmos protein
Descriptor: Protein syndesmos
Authors:Lee, I, Kim, H, Yoo, J, Cho, H, Lee, W.
Deposit date:2015-04-22
Release date:2016-04-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Crystal structure of syndesmos and its interaction with Syndecan-4 proteoglycan
Biochem.Biophys.Res.Commun., 463, 2015
2XHS
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BU of 2xhs by Molmil
Crystal structure of the ligand binding domain of Fushi tarazu factor 1 of Drosophila melanogaster.
Descriptor: NUCLEAR HORMONE RECEPTOR FTZ-F1, SEGMENTATION PROTEIN FUSHI TARAZU
Authors:Yoo, J.H, Cho, H.S.
Deposit date:2010-06-21
Release date:2011-07-20
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Fushi Tarazu Factor 1 Ligand Binding Domain/Fushi Tarazu Peptide Complex Identifies New Class of Nuclear Receptors.
J.Biol.Chem., 286, 2011
4UV7
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BU of 4uv7 by Molmil
The complex structure of extracellular domain of EGFR and GC1118A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPIDERMAL GROWTH FACTOR RECEPTOR, ...
Authors:Yoo, J.H, Cho, H.S.
Deposit date:2014-08-05
Release date:2015-10-14
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Gc1118, an Anti-Egfr Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity Against High-Affinity Egfr Ligands.
Mol.Cancer Ther., 15, 2016
4BFM
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BU of 4bfm by Molmil
The crystal structure of mouse PK38
Descriptor: MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION
Authors:Yoo, J.H, Cho, Y.S, Park, S.M, Cho, H.S.
Deposit date:2013-03-21
Release date:2014-02-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The Structures of the Kinase Domain and Uba Domain of Mpk38 Suggest the Activation Mechanism for Kinase Activity.
Acta Crystallogr.,Sect.D, 70, 2014
8DEP
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BU of 8dep by Molmil
Cryo-EM structure of the human reduced folate carrier, apo condition
Descriptor: Digitonin, Reduced folate transporter,Soluble cytochrome b562
Authors:Wright, N.J, Fedor, J.G, Lee, S.-Y.
Deposit date:2022-06-21
Release date:2022-09-21
Last modified:2022-10-12
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Methotrexate recognition by the human reduced folate carrier SLC19A1.
Nature, 609, 2022
5G1E
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BU of 5g1e by Molmil
The complex structure of syntenin-1 PDZ domain with c-terminal extension
Descriptor: SYNTENIN-1
Authors:Lee, I, Kim, H, Yun, J.H, Lee, W.
Deposit date:2016-03-25
Release date:2016-11-23
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:New Structural Insight of C-Terminal Region of Syntenin-1, Enhancing the Molecular Dimerization and Inhibitory Function Related on Syndecan-4 Signaling.
Sci.Rep., 6, 2016
4XZZ
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BU of 4xzz by Molmil
Structure of Helicobacter pylori Csd6 in the ligand-free state
Descriptor: Conserved hypothetical secreted protein, GLYCEROL
Authors:Kim, H.S, Im, H.N, Yoon, H.J, Suh, S.W.
Deposit date:2015-02-05
Release date:2015-09-02
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The Cell Shape-determining Csd6 Protein from Helicobacter pylori Constitutes a New Family of l,d-Carboxypeptidase
J.Biol.Chem., 290, 2015
4Y4V
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BU of 4y4v by Molmil
Structure of Helicobacter pylori Csd6 in the D-Ala-bound state
Descriptor: Conserved hypothetical secreted protein, D-ALANINE, GLYCEROL
Authors:Kim, H.S, Im, H.N, Yoon, H.J, Suh, S.W.
Deposit date:2015-02-11
Release date:2015-09-02
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:The Cell Shape-determining Csd6 Protein from Helicobacter pylori Constitutes a New Family of l,d-Carboxypeptidase
J.Biol.Chem., 290, 2015
8HKP
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BU of 8hkp by Molmil
Structurally hetero-junctional human Cx36/GJD2 gap junction channel in detergents (C6 symmetry)
Descriptor: Gap junction delta-2 protein, Lauryl Maltose Neopentyl Glycol
Authors:Lee, S.N, Cho, H.J, Jeong, H, Ryu, B, Lee, H.J, Lee, H.H, Woo, J.S.
Deposit date:2022-11-27
Release date:2023-03-22
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel.
Nat Commun, 14, 2023
6L3T
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BU of 6l3t by Molmil
Human Cx31.3/GJC3 connexin hemichannel in the absence of calcium
Descriptor: Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol
Authors:Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S.
Deposit date:2019-10-15
Release date:2020-09-09
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (2.34 Å)
Cite:Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel.
Sci Adv, 6, 2020
6L3V
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BU of 6l3v by Molmil
The R15G mutant of human Cx31.3/GJC3 connexin hemichannel
Descriptor: Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol
Authors:Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S.
Deposit date:2019-10-15
Release date:2020-09-09
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel.
Sci Adv, 6, 2020
6L3U
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BU of 6l3u by Molmil
Human Cx31.3/GJC3 connexin hemichannel in the presence of calcium
Descriptor: CALCIUM ION, Gap junction gamma-3 protein, Lauryl Maltose Neopentyl Glycol
Authors:Lee, H.J, Jeong, H, Ryu, B, Hyun, J, Woo, J.S.
Deposit date:2019-10-15
Release date:2020-09-09
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel.
Sci Adv, 6, 2020
5G1D
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BU of 5g1d by Molmil
The complex structure of syntenin-1 PDZ domain with c-terminal extension
Descriptor: SYNDECAN-4, SYNTENIN-1
Authors:Lee, I, Kim, H, Yun, J.H, Lee, W.
Deposit date:2016-03-25
Release date:2016-11-23
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:New Structural Insight of C-Terminal Region of Syntenin-1, Enhancing the Molecular Dimerization and Inhibitory Function Related on Syndecan-4 Signaling.
Sci.Rep., 6, 2016
2RL2
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BU of 2rl2 by Molmil
Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine and fosfomycin
Descriptor: SULFATE ION, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, ...
Authors:Yoon, H.J, Suh, S.W.
Deposit date:2007-10-18
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine and fosfomycin
Proteins, 71, 2008
2RL1
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BU of 2rl1 by Molmil
Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine
Descriptor: SULFATE ION, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
Authors:Yoon, H.J, Suh, S.W.
Deposit date:2007-10-18
Release date:2008-03-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine and fosfomycin
Proteins, 71, 2008
7TX7
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BU of 7tx7 by Molmil
Cryo-EM structure of the human reduced folate carrier
Descriptor: Digitonin, Reduced folate transporter,Soluble cytochrome b562
Authors:Wright, N.J, Fedor, J.G, Lee, S.-Y.
Deposit date:2022-02-07
Release date:2022-09-21
Last modified:2022-10-12
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Methotrexate recognition by the human reduced folate carrier SLC19A1.
Nature, 609, 2022
7TX6
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BU of 7tx6 by Molmil
Cryo-EM structure of the human reduced folate carrier in complex with methotrexate
Descriptor: Digitonin, METHOTREXATE, Reduced folate transporter,Soluble cytochrome b562
Authors:Wright, N.J, Fedor, J.G, Lee, S.-Y.
Deposit date:2022-02-07
Release date:2022-09-21
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Methotrexate recognition by the human reduced folate carrier SLC19A1.
Nature, 609, 2022
3SWE
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BU of 3swe by Molmil
Haemophilus influenzae MurA in complex with UDP-N-acetylmuramic acid and covalent adduct of PEP with Cys117
Descriptor: (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, GLYCEROL, SULFATE ION, ...
Authors:Zhu, J.-Y, Schonbrunn, E.
Deposit date:2011-07-13
Release date:2012-03-14
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Functional Consequence of Covalent Reaction of Phosphoenolpyruvate with UDP-N-acetylglucosamine 1-Carboxyvinyltransferase (MurA).
J.Biol.Chem., 287, 2012
7XQG
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BU of 7xqg by Molmil
Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (GCN conformation)
Descriptor: CHOLESTEROL HEMISUCCINATE, Gap junction alpha-1 protein, PHOSPHATIDYLETHANOLAMINE
Authors:Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S.
Deposit date:2022-05-07
Release date:2023-01-25
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023
7XQH
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BU of 7xqh by Molmil
Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (GCN-TM1i conformation)
Descriptor: C-terminal deletion mutant of gap junction alpha-1 protein (Cx43-M257)
Authors:Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S.
Deposit date:2022-05-07
Release date:2023-01-25
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023
7XQJ
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BU of 7xqj by Molmil
Hemichannel-focused structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel in POPE nanodiscs (PLN conformation)
Descriptor: Gap junction alpha-1 protein
Authors:Lee, H.J, Cha, H.J, Jeong, H, Lee, S.N, Lee, C.W, Woo, J.S.
Deposit date:2022-05-07
Release date:2023-01-25
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM.
Nat Commun, 14, 2023

 

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