Author results

3KCU
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STRUCTURE OF FORMATE CHANNEL
分子名称:Probable formate transporter 1, 2-(6-(2-CYCLOHEXYLETHOXY)-TETRAHYDRO-4,5-DIHYDROXY-2(HYDROXYMETHYL)-2H-PYRAN-3-YLOXY)-TETRAHYDRO-6(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL
著者Wang, Y., Huang, Y., Wang, J., Yan, N., Shi, Y.
登録日2009-10-22
公開日2009-12-01
最終更新日2014-01-22
実験手法X-RAY DIFFRACTION (2.243 Å)
主引用文献Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Nature, 462, 2009
3KCV
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STRUCTURE OF FORMATE CHANNEL
分子名称:Probable formate transporter 1
著者Wang, Y., Huang, Y., Wang, J., Yan, N., Shi, Y.
登録日2009-10-22
公開日2009-12-01
最終更新日2018-02-21
実験手法X-RAY DIFFRACTION (3.198 Å)
主引用文献Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Nature, 462, 2009
6K3H
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CRYSTALLOGRAPHIC ANALYSIS OF NUCLEOSIDE DIPHOSPHATE KINASE (NDK) FROM ASPERGILLUS FLAVUS
分子名称:Nucleoside diphosphate kinase
著者Wang, Y., Wang, S., Wang, S.H.
登録日2019-05-18
公開日2019-07-03
最終更新日2019-07-10
実験手法X-RAY DIFFRACTION (2.179 Å)
主引用文献Molecular and structural basis of nucleoside diphosphate kinase-mediated regulation of spore and sclerotia development in the fungusAspergillus flavus.
J.Biol.Chem., 2019
3GX8
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF YEAST MONOTHIOL GLUTAREDOXIN GRX5
分子名称:Monothiol glutaredoxin-5, mitochondrial, SULFATE ION
著者Wang, Y., He, Y.X., Yu, J., Xiong, Y., Chen, Y., Zhou, C.Z.
登録日2009-04-01
公開日2010-04-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.673 Å)
主引用文献Structural and biochemical characterization of yeast monothiol glutaredoxin Grx5
To be Published
4ZHQ
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-MMAE COMPLEX
分子名称:Tubulin alpha-1B chain, Tubulin beta chain, Stathmin-4, ...
著者Wang, Y., Zhang, R.
登録日2015-04-26
公開日2016-07-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016
4ZI7
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-HTI286 COMPLEX
分子名称:Tubulin alpha-1B chain, Tubulin beta chain, Stathmin-4, ...
著者Wang, Y., Zhang, R.
登録日2015-04-27
公開日2016-07-27
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016
4ZOL
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-TUBULYSIN M COMPLEX
分子名称:Tubulin alpha-1B chain, Tubulin beta chain, Stathmin-4, ...
著者Wang, Y., Zhang, R.
登録日2015-05-06
公開日2016-07-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules
Mol.Pharmacol., 89, 2016
5BMV
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CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-VINBLASTINE COMPLEX
分子名称:Tubulin alpha-1B chain, Tubulin beta chain, Stathmin-4, ...
著者Wang, Y., Chen, Q., Zhang, R.
登録日2015-05-23
公開日2016-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules.
Mol.Pharmacol., 89, 2016
6J07
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CRYSTAL STRUCTURE OF HUMAN TERB2 AND TERB1
分子名称:Telomere repeats-binding bouquet formation protein 2, Telomere repeats-binding bouquet formation protein 1, ZINC ION
著者Wang, Y., Chen, Y., Wu, J., Huang, C., Lei, M.
登録日2018-12-21
公開日2019-02-27
実験手法X-RAY DIFFRACTION (3.298 Å)
主引用文献The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope.
Nat Commun, 10, 2019
6J08
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CRYSTAL STRUCTURE OF HUMAN MAJIN AND TERB2
分子名称:Membrane-anchored junction protein, Telomere repeats-binding bouquet formation protein 2
著者Wang, Y., Chen, Y., Wu, J., Huang, C., Lei, M.
登録日2018-12-21
公開日2019-02-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope.
Nat Commun, 10, 2019
3TDL
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STRUCTURE OF HUMAN SERUM ALBUMIN IN COMPLEX WITH DAUDA
分子名称:Serum albumin, MYRISTIC ACID, 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)undecanoic acid
著者Wang, Y., Luo, Z., Shi, X., Wang, H., Nie, L.
登録日2011-08-11
公開日2012-06-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A fluorescent fatty acid probe, DAUDA, selectively displaces two myristates bound in human serum albumin
Protein Sci., 20, 2011
5EX7
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CRYSTAL STRUCTURE OF BRAT NHL DOMAIN IN COMPLEX WITH AN 8-NT HUNCHBACK MRNA
分子名称:Brain tumor protein, RNA (5'-R(P*UP*UP*UP*GP*UP*UP*GP*U)-3')
著者Wang, Y., Yu, Z., Wang, M., Liu, C.P., Yang, N., Xu, R.M.
登録日2015-11-23
公開日2015-12-09
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of Brat NHL domain in complex with an 8-nt hunchback mRNA
To Be Published
5IJB
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THE LIGAND-FREE STRUCTURE OF THE MOUSE TLR4/MD-2 COMPLEX
分子名称:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
著者Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
登録日2016-03-01
公開日2016-04-27
最終更新日2016-05-04
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJC
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THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/NEOSEPTIN-3 COMPLEX
分子名称:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
著者Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
登録日2016-03-01
公開日2016-04-27
最終更新日2016-05-04
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJD
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THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LIPID A COMPLEX
分子名称:Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ...
著者Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B.
登録日2016-03-01
公開日2016-04-27
最終更新日2016-05-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
5Y7L
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SOLUTION STRUCTURE OF HBETA4 EXTRACELLULAR LOOP OF BK POTASSIUM CHANNEL
分子名称:Calcium-activated potassium channel subunit beta-4
著者Wang, Y., Lan, W., Ding, J., Cao, C.
登録日2017-08-17
公開日2018-08-01
実験手法SOLUTION NMR
主引用文献Solution structure of extracellular loop of human beta 4 subunit of BK channel and its biological implication on ChTX sensitivity.
Sci Rep, 8, 2018
3B44
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CRYSTAL STRUCTURE OF GLPG W136A MUTANT
分子名称:glpG, B-NONYLGLUCOSIDE
著者Wang, Y., Maegawa, S., Akiyama, Y., Ha, Y.
登録日2007-10-23
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.
J.Mol.Biol., 374, 2007
3B45
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CRYSTAL STRUCTURE OF GLPG AT 1.9A RESOLUTION
分子名称:glpG, B-NONYLGLUCOSIDE
著者Wang, Y., Maegawa, S., Akiyama, Y., Ha, Y.
登録日2007-10-23
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.
J.Mol.Biol., 374, 2007
4XT9
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RORGAMMA (263-509) COMPLEXED WITH GSK2435341A AND SRC2
分子名称:Nuclear receptor ROR-gamma, LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, N-[4-(2,5-dichlorophenyl)-5-phenyl-1,3-thiazol-2-yl]-2-[4-(ethylsulfonyl)phenyl]acetamide, ...
著者Wang, Y., Ma, Y.
登録日2015-01-23
公開日2015-08-12
最終更新日2015-09-16
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent ROR gamma t inverse agonists
Bioorg.Med.Chem., 23, 2015
5C8Y
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CRYSTAL STRUCTURE OF T2R-TTL-PLINABULIN COMPLEX
分子名称:Tubulin alpha, Tubulin beta, Stathmin-4, ...
著者Wang, Y., Yu, Y., Chen, Q., Yang, J.
登録日2015-06-26
公開日2015-11-04
最終更新日2016-01-27
実験手法X-RAY DIFFRACTION (2.594 Å)
主引用文献Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
5CA0
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CRYSTAL STRUCTURE OF T2R-TTL-LEXIBULIN COMPLEX
分子名称:Tubulin alpha-1B chain, Uncharacterized protein, Stathmin-4, ...
著者Wang, Y., Yu, Y., Chen, Q., Yang, J.
登録日2015-06-29
公開日2015-11-04
最終更新日2016-01-27
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
5CA1
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CRYSTAL STRUCTURE OF T2R-TTL-NOCODAZOLE COMPLEX
分子名称:Tubulin alpha, Tubulin beta-2 chain, Stathmin-4, ...
著者Wang, Y., Yu, Y., Chen, Q., Yang, J.
登録日2015-06-29
公開日2015-11-04
最終更新日2016-01-27
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
5CB4
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CRYSTAL STRUCTURE OF T2R-TTL-TIVANTINIB COMPLEX
分子名称:Tubulin alpha, Tubulin beta, Stathmin-4, ...
著者Wang, Y., Yu, Y., Chen, Q., Yang, J.
登録日2015-06-30
公開日2015-11-04
最終更新日2016-01-27
実験手法X-RAY DIFFRACTION (2.193 Å)
主引用文献Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
5EZY
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CRYSTAL STRUCTURE OF T2R-TTL-TACCALONOLIDE AJ COMPLEX
分子名称:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
著者Wang, Y., Yu, Y., Chen, Q., Yang, J.
登録日2015-11-27
公開日2017-01-11
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Mechanism of microtubule stabilization by taccalonolide AJ
Nat Commun, 8, 2017
6O58
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HUMAN MCU-EMRE COMPLEX, DIMER OF CHANNEL
分子名称:Calcium uniporter protein, mitochondrial, Essential MCU regulator, ...
著者Wang, Y., Bai, X., Jiang, Y.
登録日2019-03-01
公開日2019-05-22
最終更新日2019-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter.
Cell, 177, 2019