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4IRP
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BU of 4irp by Molmil
Crystal structure of catalytic domain of human beta1,4-galactosyltransferase-7 in open conformation with manganses and UDP
Descriptor: ACETATE ION, Beta-1,4-galactosyltransferase 7, IMIDAZOLE, ...
Authors:Tsutsui, Y, Ramakrishnan, B, Qasba, P.K.
Deposit date:2013-01-15
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding.
J.Biol.Chem., 288, 2013
4IRQ
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BU of 4irq by Molmil
Crystal structure of catalytic domain of human beta1,4galactosyltransferase 7 in closed conformation in complex with manganese and UDP
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-1,4-galactosyltransferase 7, MANGANESE (II) ION, ...
Authors:Tsutsui, Y, Ramakrishnan, B, Qasba, P.K.
Deposit date:2013-01-15
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of beta-1,4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding.
J.Biol.Chem., 288, 2013
3VIQ
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BU of 3viq by Molmil
Crystal structure of Swi5-Sfr1 complex from fission yeast
Descriptor: GLYCEROL, Mating-type switching protein swi5, NITRATE ION, ...
Authors:Kuwabara, N, Murayama, Y, Hashimoto, H, Kokabu, Y, Ikeguchi, M, Sato, M, Mayanagi, K, Tsutsui, Y, Iwasaki, H, Shimizu, T.
Deposit date:2011-10-06
Release date:2012-08-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanistic insights into the activation of Rad51-mediated strand exchange from the structure of a recombination activator, the Swi5-Sfr1 complex
Structure, 20, 2012
4LW6
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BU of 4lw6 by Molmil
Crystal structure of catalytic domain of Drosophila beta1,4galactosyltransferase 7 complex with xylobiose
Descriptor: 2-AMINO-1,3-PROPANEDIOL, Beta-4-galactosyltransferase 7, MANGANESE (II) ION, ...
Authors:Qasba, P.K, Ramakrishnan, B.
Deposit date:2013-07-26
Release date:2013-09-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding.
J.Biol.Chem., 288, 2013
4LW3
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BU of 4lw3 by Molmil
Crystal structure of the Drosophila beta1,4galactosyltransferase7 catalytic domain D211N single mutant enzyme complex with manganese and UDP-galactose
Descriptor: Beta-4-galactosyltransferase 7, GALACTOSE-URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION
Authors:Ramakrishnan, B, Qasba, P.K.
Deposit date:2013-07-26
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding.
J.Biol.Chem., 288, 2013
4M4K
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BU of 4m4k by Molmil
Crystal structure of the Drosphila beta,14galactosyltransferase 7 mutant D211N complex with manganese, UDP-Gal and xylobiose
Descriptor: Beta-4-galactosyltransferase 7, CHLORIDE ION, GALACTOSE-URIDINE-5'-DIPHOSPHATE, ...
Authors:Ramakrishnan, B, Qasba, P.K.
Deposit date:2013-08-07
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding.
J.Biol.Chem., 288, 2013
7TVD
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BU of 7tvd by Molmil
Crystal structure of the kinase domain of EGFR exon-19 (del-747-749) mutant
Descriptor: Epidermal growth factor receptor
Authors:Ashtekar, K.D, Stayrook, S.E, Lemmon, M.A.
Deposit date:2022-02-04
Release date:2022-02-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Biochemical and structural basis for differential inhibitor sensitivity of EGFR with distinct exon 19 mutations.
Nat Commun, 13, 2022
7LS0
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BU of 7ls0 by Molmil
Structure of the Human ALK GRD bound to AUG
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor fused with ALK and LTK ligand 2, CITRIC ACID
Authors:Stayrook, S, Li, T, Klein, D.E.
Deposit date:2021-02-17
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
7LIR
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BU of 7lir by Molmil
Structure of the invertebrate ALK GRD
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor homolog scd-2, ...
Authors:Stayrook, S, Li, T, Klein, D.E.
Deposit date:2021-01-27
Release date:2021-11-24
Last modified:2021-12-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
7LRZ
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BU of 7lrz by Molmil
Structure of the Human ALK GRD
Descriptor: ALK tyrosine kinase receptor
Authors:Stayrook, S, Li, T, Klein, D.E.
Deposit date:2021-02-17
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
7MK7
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BU of 7mk7 by Molmil
Augmentor domain of augmentor-beta
Descriptor: ALK and LTK ligand 1,Maltodextrin-binding protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Krimmer, S.G, Reshetnyak, A.V, Puleo, D.E, Schlessinger, J.
Deposit date:2021-04-21
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.42815185 Å)
Cite:Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
3VIR
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BU of 3vir by Molmil
Crystal strcture of Swi5 from fission yeast
Descriptor: Mating-type switching protein swi5, octyl beta-D-glucopyranoside
Authors:Kuwabara, N, Yamada, N, Hashimoto, H, Sato, M, Iwasaki, H, Shimizu, T.
Deposit date:2011-10-06
Release date:2012-08-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanistic insights into the activation of Rad51-mediated strand exchange from the structure of a recombination activator, the Swi5-Sfr1 complex
Structure, 20, 2012
6TU9
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BU of 6tu9 by Molmil
The ROR1 Pseudokinase Domain Bound To Ponatinib
Descriptor: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Inactive tyrosine-protein kinase transmembrane receptor ROR1
Authors:Mathea, S, Preuss, F, Chatterjee, D, Niininen, W, Ungureanu, D, Shin, D, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S.
Deposit date:2020-01-04
Release date:2020-01-22
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases.
Mol.Cell, 79, 2020
6TUA
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BU of 6tua by Molmil
The RYK Pseudokinase Domain
Descriptor: SULFATE ION, Tyrosine-protein kinase RYK
Authors:Mathea, S, Chatterjee, D, Preuss, F, Shin, D, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S.
Deposit date:2020-01-04
Release date:2020-01-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases.
Mol.Cell, 79, 2020

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PDB entries from 2024-03-27

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