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7QNG
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BU of 7qng by Molmil
Structure of a MHC I-Tapasin-ERp57 complex
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
Authors:Mueller, I.K, Thomas, C, Trowitzsch, S, Tampe, R.
Deposit date:2021-12-20
Release date:2022-09-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of an MHC I-tapasin-ERp57 editing complex defines chaperone promiscuity.
Nat Commun, 13, 2022
8OMR
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BU of 8omr by Molmil
Human tRNA guanine transglycosylase (TGT) bound to tRNAAsp
Descriptor: 9-DEAZAGUANINE, Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase catalytic subunit 1, ...
Authors:Sievers, K, Neumann, P, Susac, L, Trowitzsch, S, Tampe, R, Ficner, R.
Deposit date:2023-03-31
Release date:2023-12-20
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural and functional insights into tRNA recognition by human tRNA guanine transglycosylase.
Structure, 32, 2024
6TMF
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BU of 6tmf by Molmil
Structure of an archaeal ABCE1-bound ribosomal post-splitting complex
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Kratzat, H, Becker, T, Tampe, R, Beckmann, R.
Deposit date:2019-12-04
Release date:2020-02-12
Last modified:2020-05-13
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex.
Embo J., 39, 2020
7QPD
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BU of 7qpd by Molmil
Structure of the human MHC I peptide-loading complex editing module
Descriptor: Beta-2-microglobulin, Calreticulin, HLA class I histocompatibility antigen, ...
Authors:Domnick, A, Susac, L, Trowitzsch, S, Thomas, C, Tampe, R.
Deposit date:2022-01-03
Release date:2022-07-20
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Molecular basis of MHC I quality control in the peptide loading complex.
Nat Commun, 13, 2022
4K8O
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BU of 4k8o by Molmil
CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF TAP1 WITH ATP (D645N, D651A MUTANT)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Antigen peptide transporter 1, CITRIC ACID, ...
Authors:Vakkasoglu, A.S, Grossmann, N, Hulpke, S, Abele, R, Tampe, R, Gaudet, R.
Deposit date:2013-04-18
Release date:2014-09-03
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter.
Nat Commun, 5, 2014
1QLO
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BU of 1qlo by Molmil
Structure of the active domain of the herpes simplex virus protein ICP47 in water/sodium dodecyl sulfate solution determined by nuclear magnetic resonance spectroscopy
Descriptor: HERPES SIMPLEX VIRUS PROTEIN ICP47
Authors:Pfaender, R, Neumann, L, Zweckstetter, M, Seger, C, Holak, T.A, Tampe, R.
Deposit date:1999-09-09
Release date:1999-12-14
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:The Structure of the Active Domain of the Herpes Simplex Virus Protein Icp47 in Water/Sodium Dodecyl Sulfate Solution Determined by Nuclear Magnetic Resonance Spectroscopy.
Biochemistry, 38, 1999
6ENY
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BU of 6eny by Molmil
Structure of the human PLC editing module
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Calreticulin, ...
Authors:Trowitzsch, S, Januliene, D, Blees, A, Moeller, A, Tampe, R.
Deposit date:2017-10-07
Release date:2017-11-29
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structure of the human MHC-I peptide-loading complex.
Nature, 551, 2017
7PHR
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BU of 7phr by Molmil
Structure of a fully assembled T-cell receptor engaging a tumor-associated peptide-MHC I
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Susac, L, Thomas, C, Tampe, R.
Deposit date:2021-08-18
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC.
Cell, 185, 2022
3OZX
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BU of 3ozx by Molmil
Crystal structure of ABCE1 of Sulfolubus solfataricus (-FeS domain)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Barthelme, D, Tampe, R.
Deposit date:2010-09-27
Release date:2011-02-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Ribosome Recycling in Archaea A Mechanistic Link between FeS Cluster Biosynthesis and Conformational Switch of Twin-ATPase ABCE1
To be Published
5OPI
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BU of 5opi by Molmil
Crystal structure of the TAPBPR-MHC I peptide editing complex
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
Authors:Thomas, C, Tampe, R.
Deposit date:2017-08-09
Release date:2017-10-18
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the TAPBPR-MHC I complex defines the mechanism of peptide loading and editing.
Science, 358, 2017
5LL6
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BU of 5ll6 by Molmil
Structure of the 40S ABCE1 post-splitting complex in ribosome recycling and translation initiation
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Heuer, A, Gerovac, M, Schmidt, C, Trowitzsch, S, Preis, A, Koetter, P, Berninghausen, O, Becker, T, Beckmann, R, Tampe, R.
Deposit date:2016-07-26
Release date:2017-04-12
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation.
Nat. Struct. Mol. Biol., 24, 2017
5LW7
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BU of 5lw7 by Molmil
S. solfataricus ABCE1 post-splitting state
Descriptor: ABC transporter ATP-binding protein, IRON/SULFUR CLUSTER
Authors:Heuer, A, Gerovac, M, Beckmann, R, Tampe, R.
Deposit date:2016-09-15
Release date:2016-11-16
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Structure of the ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry.
Nat Commun, 7, 2016
5MKK
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BU of 5mkk by Molmil
Crystal structure of the heterodimeric ABC transporter TmrAB, a homolog of the antigen translocation complex TAP
Descriptor: Multidrug resistance ABC transporter ATP-binding and permease protein, SULFATE ION
Authors:Noell, A, Thomas, C, Tomasiak, T.M, Olieric, V, Wang, M, Diederichs, K, Stroud, R.M, Pos, K.M, Tampe, R.
Deposit date:2016-12-05
Release date:2017-01-18
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6RAM
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BU of 6ram by Molmil
Heterodimeric ABC exporter TmrAB under turnover conditions in asymmetric unlocked return conformation with wider opened intracellular gate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
Deposit date:2019-04-06
Release date:2019-07-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6RAH
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BU of 6rah by Molmil
Heterodimeric ABC exporter TmrAB in ATP-bound outward-facing open conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding and permease protein, ...
Authors:Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
Deposit date:2019-04-06
Release date:2019-07-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6RAG
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BU of 6rag by Molmil
Heterodimeric ABC exporter TmrAB in inward-facing wide conformation under turnover conditions
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
Deposit date:2019-04-06
Release date:2019-07-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6RAN
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BU of 6ran by Molmil
Heterodimeric ABC exporter TmrAB in inward-facing wide conformation
Descriptor: Multidrug resistance ABC transporter ATP-binding and permease protein, Nanobody Nb9F10
Authors:Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
Deposit date:2019-04-06
Release date:2019-07-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6RAJ
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BU of 6raj by Molmil
Heterodimeric ABC exporter TmrAB in vanadate trapped outward-facing open conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, MAGNESIUM ION, ...
Authors:Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
Deposit date:2019-04-06
Release date:2019-07-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6RAK
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BU of 6rak by Molmil
Heterodimeric ABC exporter TmrAB in vanadate trapped outward-facing occluded conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ADP ORTHOVANADATE, MAGNESIUM ION, ...
Authors:Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
Deposit date:2019-04-06
Release date:2019-07-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6RAI
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BU of 6rai by Molmil
Heterodimeric ABC exporter TmrAB in ATP-bound outward-facing occluded conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding and permease protein, ...
Authors:Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
Deposit date:2019-04-06
Release date:2019-07-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6RAF
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BU of 6raf by Molmil
Heterodimeric ABC exporter TmrAB in inward-facing narrow conformation under turnover conditions
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Anti-vesicular stomatitis virus N VHH, ...
Authors:Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
Deposit date:2019-04-06
Release date:2019-07-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
6RAL
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BU of 6ral by Molmil
Heterodimeric ABC exporter TmrAB under turnover conditions in asymmetric unlocked return conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R.
Deposit date:2019-04-06
Release date:2019-07-31
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Conformation space of a heterodimeric ABC exporter under turnover conditions.
Nature, 571, 2019
7ZRZ
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BU of 7zrz by Molmil
Structure of the human tRNA splicing endonuclease defines substrate recognition
Descriptor: pre-tRNA Arg TCT 3-2, tRNA-splicing endonuclease subunit Sen15, tRNA-splicing endonuclease subunit Sen2, ...
Authors:Sekulovski, S, Trowitzsch, S.
Deposit date:2022-05-05
Release date:2023-05-17
Last modified:2023-06-28
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural basis of substrate recognition by human tRNA splicing endonuclease TSEN.
Nat.Struct.Mol.Biol., 30, 2023
5LIS
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BU of 5lis by Molmil
Insulin solved by Native SAD from a dataset collected in one second
Descriptor: Insulin
Authors:Casanas, A, Finke, A, Wang, M.
Deposit date:2016-07-15
Release date:2016-08-03
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (2.293 Å)
Cite:EIGER detector: application in macromolecular crystallography.
Acta Crystallogr D Struct Biol, 72, 2016
5LIN
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BU of 5lin by Molmil
Lysozyme, collected at rotation 1 degree per second
Descriptor: CHLORIDE ION, Lysozyme C
Authors:Casanas, A, Finke, A, Wang, M.
Deposit date:2016-07-15
Release date:2016-08-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.496 Å)
Cite:EIGER detector: application in macromolecular crystallography.
Acta Crystallogr D Struct Biol, 72, 2016

 

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