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1CC0
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BU of 1cc0 by Molmil
CRYSTAL STRUCTURE OF THE RHOA.GDP-RHOGDI COMPLEX
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, rho GDP dissociation inhibitor alpha, ...
Authors:Longenecker, K.L, Read, P, Derewenda, U, Dauter, Z, Garrard, S, Walker, L, Somlyo, A.V, Somlyo, A.P, Nakamoto, R.K, Derewenda, Z.S.
Deposit date:1999-03-03
Release date:2000-01-07
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (5 Å)
Cite:How RhoGDI binds Rho.
Acta Crystallogr.,Sect.D, 55, 1999
1XCG
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BU of 1xcg by Molmil
Crystal Structure of Human RhoA in complex with DH/PH fragment of PDZRHOGEF
Descriptor: Rho guanine nucleotide exchange factor 11, Transforming protein RhoA
Authors:Derewenda, U, Oleksy, A, Stevenson, A.S, Korczynska, J, Dauter, Z, Somlyo, A.P, Otlewski, J, Somlyo, A.V, Derewenda, Z.S.
Deposit date:2004-09-01
Release date:2004-12-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle
Structure, 12, 2004
1FHG
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BU of 1fhg by Molmil
HIGH RESOLUTION REFINEMENT OF TELOKIN
Descriptor: TELOKIN
Authors:Tomchick, D.R, Minor, W, Kiyatkin, A, Lewinski, K, Somlyo, A.V, Somlyo, A.P.
Deposit date:2000-08-01
Release date:2000-08-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure determination of telokin, the C-terminal domain of myosin light chain kinase, at 2.8 A resolution.
J.Mol.Biol., 227, 1992
1FTN
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BU of 1ftn by Molmil
CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA (H12)
Authors:Wei, Y, Zhang, Y, Derewenda, U, Liu, X, Minor, W, Nakamoto, R.K, Somlyo, A.V, Somlyo, A.P, Derewenda, Z.S.
Deposit date:1997-03-13
Release date:1998-03-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of RhoA-GDP and its functional implications.
Nat.Struct.Biol., 4, 1997
3T06
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BU of 3t06 by Molmil
Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA
Descriptor: Rho guanine nucleotide exchange factor 11, Transforming protein RhoA
Authors:Bielnicki, J.A, Derewenda, U, Derewenda, Z.S.
Deposit date:2011-07-19
Release date:2011-08-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Insights into the Molecular Activation Mechanism of the RhoA-specific Guanine Nucleotide Exchange Factor, PDZRhoGEF.
J.Biol.Chem., 286, 2011
3MSX
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BU of 3msx by Molmil
Crystal structure of RhoA.GDP.MgF3 in complex with GAP domain of ArhGAP20
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 20, ...
Authors:Utepbergenov, D, Cooper, D.R, Derewenda, U, Derewenda, Z.S.
Deposit date:2010-04-29
Release date:2011-03-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Mechanism of molecular specificity of RhoGAP domains towards small GTPases of RhoA family.
To be Published
5IRC
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BU of 5irc by Molmil
p190A GAP domain complex with RhoA
Descriptor: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Derewenda, U, Derewenda, Z.
Deposit date:2016-03-12
Release date:2016-08-17
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
J.Biol.Chem., 291, 2016
4GUE
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BU of 4gue by Molmil
Structure of N-terminal kinase domain of RSK2 with flavonoid glycoside quercitrin
Descriptor: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside, MAGNESIUM ION, Ribosomal protein S6 kinase alpha-3, ...
Authors:Derewenda, U, Utepbergenov, D, Szukalska, G, Derewenda, Z.S.
Deposit date:2012-08-29
Release date:2013-01-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 69, 2013

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