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6ZE1
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BU of 6ze1 by Molmil
human NBD1 of CFTR in complex with nanobody G11a
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ...
Authors:Garcia-Pino, A, Govaerts, C, Scholl, D, Sigoillot, M.
Deposit date:2020-06-15
Release date:2021-06-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.705 Å)
Cite:A topological switch in CFTR modulates channel activity and sensitivity to unfolding.
Nat.Chem.Biol., 17, 2021
3J9R
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BU of 3j9r by Molmil
Atomic structures of a bactericidal contractile nanotube in its pre- and post-contraction states
Descriptor: sheath
Authors:Ge, P, Scholl, D, Leiman, P.G, Yu, X, Miller, J.F, Zhou, Z.H.
Deposit date:2015-02-17
Release date:2015-04-01
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states.
Nat.Struct.Mol.Biol., 22, 2015
3J9Q
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BU of 3j9q by Molmil
Atomic structures of a bactericidal contractile nanotube in its pre- and post-contraction states
Descriptor: sheath, tube
Authors:Ge, P, Scholl, D, Leiman, P.G, Yu, X, Miller, J.F, Zhou, Z.H.
Deposit date:2015-02-17
Release date:2015-04-01
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states.
Nat.Struct.Mol.Biol., 22, 2015
6PYT
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BU of 6pyt by Molmil
CryoEM Structure of Pyocin R2 - precontracted - trunk
Descriptor: Pyocin sheath PA0622, Pyocin tube PA0623
Authors:Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H.
Deposit date:2019-07-30
Release date:2020-04-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
6GJQ
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BU of 6gjq by Molmil
human NBD1 of CFTR in complex with nanobody T27
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, Nanobody T27
Authors:Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C.
Deposit date:2018-05-16
Release date:2019-06-19
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nat Commun, 10, 2019
6GKD
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BU of 6gkd by Molmil
human NBD1 of CFTR in complex with nanobodies D12 and G3a
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, GLYCEROL, ...
Authors:Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C.
Deposit date:2018-05-18
Release date:2019-06-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nat Commun, 10, 2019
6GJU
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BU of 6gju by Molmil
human NBD1 of CFTR in complex with nanobodies T2a and T4
Descriptor: Cystic fibrosis transmembrane conductance regulator, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C.
Deposit date:2018-05-17
Release date:2019-06-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nat Commun, 10, 2019
6GJS
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BU of 6gjs by Molmil
Human NBD1 of CFTR in complex with nanobodies D12 and T4
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ...
Authors:Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C.
Deposit date:2018-05-16
Release date:2019-06-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nat Commun, 10, 2019
6GK4
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BU of 6gk4 by Molmil
Human NBD1 of CFTR in complex with nanobodies D12 and T8
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, GLYCEROL, ...
Authors:Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C.
Deposit date:2018-05-18
Release date:2019-06-19
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Nat Commun, 10, 2019
6U5B
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BU of 6u5b by Molmil
CryoEM Structure of Pyocin R2 - precontracted - baseplate
Descriptor: Glue PA0627, Ripcord PA0626, Sheath Initiator PA0617, ...
Authors:Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H.
Deposit date:2019-08-27
Release date:2020-04-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
6U5H
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BU of 6u5h by Molmil
CryoEM Structure of Pyocin R2 - precontracted - hub
Descriptor: Probable bacteriophage protein Pyocin R2
Authors:Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H.
Deposit date:2019-08-27
Release date:2020-04-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
6U5K
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BU of 6u5k by Molmil
CryoEM Structure of Pyocin R2 - postcontracted - baseplate
Descriptor: Glue PA0627, Sheath Initiator PA0617, Sheath PA0622, ...
Authors:Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H.
Deposit date:2019-08-27
Release date:2020-04-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
6U5F
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BU of 6u5f by Molmil
CryoEM Structure of Pyocin R2 - precontracted - collar
Descriptor: Collar PA0615, Sheath PA0622, Tube PA0623
Authors:Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H.
Deposit date:2019-08-27
Release date:2020-04-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
6U5J
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BU of 6u5j by Molmil
CryoEM Structure of Pyocin R2 - postcontracted - collar
Descriptor: Collar PA0615, Sheath PA0622
Authors:Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H.
Deposit date:2019-08-27
Release date:2020-04-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
5CES
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BU of 5ces by Molmil
C-terminal domain of the R-type pyocin baseplate protein PA0618
Descriptor: PA0618
Authors:Plattner, M, Buth, S.A, Shneider, M.M, Leiman, P.G.
Deposit date:2015-07-07
Release date:2016-07-27
Last modified:2020-05-13
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
6CL5
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BU of 6cl5 by Molmil
Structure of P. aeruginosa R1 pyocin fiber PALES_06171 comprising C-terminal residues 323-701
Descriptor: FE (III) ION, MAGNESIUM ION, SODIUM ION, ...
Authors:Buth, S.A, Shneider, M.M, Leiman, P.G.
Deposit date:2018-03-01
Release date:2018-06-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.324 Å)
Cite:Structure and Analysis of R1 and R2 Pyocin Receptor-Binding Fibers.
Viruses, 10, 2018
6CL6
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BU of 6cl6 by Molmil
Structure of P. aeruginosa R2 pyocin fiber PA0620 comprising C-terminal residues 323-691
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, FE (III) ION, ...
Authors:Buth, S.A, Shneider, M.M, Leiman, P.G.
Deposit date:2018-03-01
Release date:2018-06-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.898 Å)
Cite:Structure and Analysis of R1 and R2 Pyocin Receptor-Binding Fibers.
Viruses, 10, 2018
5W5E
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BU of 5w5e by Molmil
Re-refinement of the pyocin tube structure
Descriptor: FIIR2 protein
Authors:Wang, F, Zheng, W, Taylor, N.M, Guerrero-Ferreira, R.C, Leiman, P.G, Egelman, E.H.
Deposit date:2017-06-15
Release date:2017-08-16
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Refined Cryo-EM Structure of the T4 Tail Tube: Exploring the Lowest Dose Limit.
Structure, 25, 2017
6S2U
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BU of 6s2u by Molmil
Structure of the catalytic domain of T. thermophilus Rel in complex with AMP and ppGpp
Descriptor: (P)ppGpp synthetase I, SpoT/RelA, ADENOSINE MONOPHOSPHATE, ...
Authors:Garcia-Pino, A.
Deposit date:2019-06-22
Release date:2020-07-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes.
Nat.Chem.Biol., 16, 2020
6S2V
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BU of 6s2v by Molmil
Structure of the N-terminal catalytic region of T. thermophilus Rel
Descriptor: (P)ppGpp synthetase I, SpoT/RelA, CHLORIDE ION, ...
Authors:Garcia-Pino, A.
Deposit date:2019-06-22
Release date:2020-07-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes.
Nat.Chem.Biol., 16, 2020
6S2T
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BU of 6s2t by Molmil
Structure of the N-terminal catalytic region of T. thermophilus Rel bound to ppGpp
Descriptor: (P)ppGpp synthetase I, SpoT/RelA, CHLORIDE ION, ...
Authors:Garcia-Pino, A.
Deposit date:2019-06-22
Release date:2020-07-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes.
Nat.Chem.Biol., 16, 2020

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