Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2HT6
DownloadVisualize
BU of 2ht6 by Molmil
Crystal structure of Human Gem G-domain bound to GDP
Descriptor: GTP-binding protein GEM, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Opatowsky, Y, Hirsch, J.A.
Deposit date:2006-07-25
Release date:2006-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-function studies of the G-domain from human gem, a novel small G-protein.
Febs Lett., 580, 2006
1T3S
DownloadVisualize
BU of 1t3s by Molmil
Structural Analysis of the Voltage-Dependent Calcium Channel Beta Subunit Functional Core
Descriptor: Dihydropyridine-sensitive L-type, calcium channel beta-2 subunit, MERCURY (II) ION
Authors:Opatowsky, Y, Chen, C.-C, Campbell, K.P, Hirsch, J.A.
Deposit date:2004-04-27
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of the voltage-dependent calcium channel beta subunit functional core and its complex with the alpha 1 interaction domain.
Neuron, 42, 2004
1T3L
DownloadVisualize
BU of 1t3l by Molmil
Structural Analysis of the Voltage-Dependent Calcium Channel Beta Subunit Functional Core in Complex with Alpha1 Interaction Domain
Descriptor: Dihydropyridine-sensitive L-type, calcium channel beta-2 subunit, Voltage-dependent L-type calcium channel alpha-1S subunit
Authors:Opatowsky, Y, Chen, C.-C, Campbell, K.P, Hirsch, J.A.
Deposit date:2004-04-27
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of Voltage-Dependent Calcium Channel Beta Subunit Functional Core and Its Complex with the Alpha1 Interaction Domain
NEURON, 42, 2004
4PQJ
DownloadVisualize
BU of 4pqj by Molmil
Crystal structure of a phosphate binding protein
Descriptor: PHOSPHATE ION, Phosphate binding protein
Authors:Opatowsky, Y, Neznansky, A.
Deposit date:2014-03-03
Release date:2015-03-18
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal structure of a phosphate binding protein
TO BE PUBLISHED
5NOI
DownloadVisualize
BU of 5noi by Molmil
human Robo2 extracellular domains 4-5
Descriptor: Roundabout homolog 2
Authors:Opatowsky, Y, Barak, R.
Deposit date:2017-04-12
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Robo Ig4 Is a Dimerization Domain.
J. Mol. Biol., 429, 2017
4RTT
DownloadVisualize
BU of 4rtt by Molmil
Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment
Descriptor: SLIT-ROBO Rho GTPase-activating protein 2, SULFATE ION
Authors:Opatowsky, Y, Guez-Hadad, J.
Deposit date:2014-11-16
Release date:2015-11-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism.
Structure, 23, 2015
4RUG
DownloadVisualize
BU of 4rug by Molmil
Cyrstal structure of SLIT-ROBO Rho GTPase-activating protein 2 fragment
Descriptor: SLIT-ROBO Rho GTPase-activating protein 2
Authors:Opatowsky, Y, Guez-Hadad, J.
Deposit date:2014-11-19
Release date:2015-11-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism.
Structure, 23, 2015
6ZG0
DownloadVisualize
BU of 6zg0 by Molmil
SARM1 SAM1-2 domains
Descriptor: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y.
Deposit date:2020-06-18
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
3KVQ
DownloadVisualize
BU of 3kvq by Molmil
Crystal structure of VEGFR2 extracellular domain D7
Descriptor: Vascular endothelial growth factor receptor 2
Authors:Yang, Y, Opatowsky, Y, Xie, P, Schlessinger, J.
Deposit date:2009-11-30
Release date:2010-02-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling
Proc.Natl.Acad.Sci.USA, 107, 2010
6QWV
DownloadVisualize
BU of 6qwv by Molmil
SARM1 SAM1-2 domains
Descriptor: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Sporny, M, Isupov, N.M, Opatowsky, Y.
Deposit date:2019-03-06
Release date:2019-07-03
Last modified:2019-09-18
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structural Evidence for an Octameric Ring Arrangement of SARM1.
J.Mol.Biol., 431, 2019
4HLJ
DownloadVisualize
BU of 4hlj by Molmil
Axon Guidance Receptor
Descriptor: PENTAETHYLENE GLYCOL, Roundabout homolog 1
Authors:Barak, R, Opatowsky, Y.
Deposit date:2012-10-17
Release date:2013-11-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Axon Guidance Receptor
To be Published
8P2M
DownloadVisualize
BU of 8p2m by Molmil
C. elegans TIR-1 protein.
Descriptor: NAD(+) hydrolase tir-1
Authors:Isupov, M.N, Opatowsky, Y.
Deposit date:2023-05-16
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (3.82 Å)
Cite:Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023
8P2L
DownloadVisualize
BU of 8p2l by Molmil
A CHIMERA construct containing human SARM1 ARM and SAM domains and C. elegans TIR domain.
Descriptor: NAD(+) hydrolase SARM1,NAD(+) hydrolase tir-1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Isupov, M.N, Opatowsky, Y.
Deposit date:2023-05-16
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023
6ZFX
DownloadVisualize
BU of 6zfx by Molmil
hSARM1 GraFix-ed
Descriptor: (~{E})-4-methylnon-4-enedial, NAD(+) hydrolase SARM1
Authors:Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y.
Deposit date:2020-06-18
Release date:2020-11-18
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
6ZG1
DownloadVisualize
BU of 6zg1 by Molmil
SARM1 SAM1-2 domains
Descriptor: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y.
Deposit date:2020-06-18
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
7ANW
DownloadVisualize
BU of 7anw by Molmil
hSARM1 NAD+ complex
Descriptor: NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Mim, C, Isupov, M.N, Zalk, R, Dessau, M, Hons, M, Opatowsky, Y.
Deposit date:2020-10-13
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
6I9S
DownloadVisualize
BU of 6i9s by Molmil
hRobo2 Extracellular Domains 2-3
Descriptor: Roundabout homolog 2, SODIUM ION
Authors:Barak, R, Isupov, N.M, Opatowsky, Y.
Deposit date:2018-11-25
Release date:2019-03-13
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural Principles in Robo Activation and Auto-inhibition.
Cell, 177, 2019
6IAA
DownloadVisualize
BU of 6iaa by Molmil
hRobo2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Roundabout homolog 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Barak, R, Isupov, N.M, Opatowsky, Y.
Deposit date:2018-11-26
Release date:2019-03-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural Principles in Robo Activation and Auto-inhibition.
Cell, 177, 2019
2E9W
DownloadVisualize
BU of 2e9w by Molmil
Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Kit ligand, Mast/stem cell growth factor receptor
Authors:Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J.
Deposit date:2007-01-27
Release date:2007-08-07
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor
Cell(Cambridge,Mass.), 130, 2007
2EC8
DownloadVisualize
BU of 2ec8 by Molmil
Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Mast/stem cell growth factor receptor
Authors:Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J.
Deposit date:2007-02-11
Release date:2007-08-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor
Cell(Cambridge,Mass.), 130, 2007
5I6J
DownloadVisualize
BU of 5i6j by Molmil
Crystal Structure of SRGAP2 F-BARx
Descriptor: SLIT-ROBO Rho GTPase-activating protein 2
Authors:Sporny, M, Guez-Haddad, J, Isupov, M.N, Opatowsky, Y.
Deposit date:2016-02-16
Release date:2017-03-08
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural History of Human SRGAP2 Proteins.
Mol. Biol. Evol., 34, 2017
5I7D
DownloadVisualize
BU of 5i7d by Molmil
Crystal Structure of srGAP2 F-BARx WT Form-2
Descriptor: SLIT-ROBO Rho GTPase-activating protein 2
Authors:Sporny, M, Guez-Haddad, J, Isupov, M.N, Opatowsky, Y.
Deposit date:2016-02-17
Release date:2017-08-30
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Structural Basis for srGAP2 Membrane Interactions, and Antagonism by the Human Specific Paralog srGAP2C
To Be Published
5I6R
DownloadVisualize
BU of 5i6r by Molmil
Crystal Structure of srGAP2 F-BARx WT Form-1
Descriptor: ACETATE ION, D-MALATE, SLIT-ROBO Rho GTPase-activating protein 2, ...
Authors:Sporny, M, Guez-Haddad, J, Isupov, M.N, Opatowsky, Y.
Deposit date:2016-02-16
Release date:2017-08-30
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural Basis for srGAP2 Membrane Interactions, and Antagonism by the Human Specific Paralog srGAP2C
To Be Published
4OMB
DownloadVisualize
BU of 4omb by Molmil
Phosphate binding protein
Descriptor: PHOSPHATE ION, PLATINUM (II) ION, Phosphate binding protein
Authors:Neznansky, A, Opatowsky, Y.
Deposit date:2014-01-27
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Pseudomonas aeruginosa phosphate transport protein PstS plays a phosphate-independent role in biofilm formation.
Faseb J., 28, 2014
7QG0
DownloadVisualize
BU of 7qg0 by Molmil
Inhibitor-induced hSARM1 duplex
Descriptor: NAD(+) hydrolase SARM1
Authors:Zalk, R, Kahzma, T, Guez-Haddad, J.
Deposit date:2021-12-07
Release date:2022-12-21
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:A duplex structure of SARM1 octamers stabilized by a new inhibitor.
Cell.Mol.Life Sci., 80, 2022

 

12>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon