Author results

6N9E
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH A SHORT SUBSTRATE MIMIC CC-PMN AND BOUND TO MRNA AND P-SITE TRNA AT 3.7A RESOLUTION
分子名称:23S Ribosomal RNA, 5S Ribosomal RNA, 50S Ribosomal Protein L2, ...
著者Melnikov, S.V., Khabibullina, N.F., Mairhofer, E., Vargas-Rodriguez, O., Reynolds, N.M., Micura, R., Soll, D., Polikanov, Y.S.
登録日2018-12-03
公開日2018-12-12
最終更新日2019-03-13
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site.
Nucleic Acids Res., 47, 2019
6N9F
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH A SHORT SUBSTRATE MIMIC ACCA-DPHE AND BOUND TO MRNA AND P-SITE TRNA AT 3.7A RESOLUTION
分子名称:23S Ribosomal RNA, 5S Ribosomal RNA, 50S Ribosomal Protein L2, ...
著者Melnikov, S.V., Khabibullina, N.F., Mairhofer, E., Vargas-Rodriguez, O., Reynolds, N.M., Micura, R., Soll, D., Polikanov, Y.S.
登録日2018-12-03
公開日2018-12-12
最終更新日2019-03-13
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site.
Nucleic Acids Res., 47, 2019
5MRX
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27-NT SRL WITH A 5-HYDROXYMETHYL CYTIDINE MODIFICATION
分子名称:RNA (27-MER)
著者Ennifar, E., Micura, R.
登録日2016-12-28
公開日2018-01-17
実験手法X-RAY DIFFRACTION (0.851 Å)
主引用文献Xray structure of 5hmrc-modified RNA at atomic resolution
To Be Published
5Y85
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STRUCTURE-BASED INSIGHTS INTO SELF-CLEAVAGE BY A FOUR-WAY JUNCTIONAL TWISTER-SISTER RIBOZYME
分子名称:RNA (5'-R(P*AP*CP*CP*CP*GP*CP*AP*AP*GP*GP*CP*CP*GP*AP*CP*GP*GP*C)-3'), DNA/RNA (50-MER), MAGNESIUM ION
著者Zheng, L., Micura, R.L., Ren, A.
登録日2017-08-18
公開日2017-11-22
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme
Nat Commun, 8, 2017
5Y87
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STRUCTURE-BASED INSIGHTS INTO SELF-CLEAVAGE BY A FOUR-WAY JUNCTIONAL TWISTER-SISTER RIBOZYME
分子名称:RNA (5'-R(P*AP*CP*CP*CP*GP*CP*AP*AP*GP*GP*CP*CP*GP*AP*CP*GP*GP*C)-3'), DNA/RNA (50-MER), MANGANESE (II) ION
著者Zheng, L., Micura, R.L., Ren, A.
登録日2017-08-19
公開日2017-11-22
最終更新日2019-01-23
実験手法X-RAY DIFFRACTION (2.132 Å)
主引用文献Structure-based insights into self-cleavage by a four-way junctional twister-sister ribozyme
Nat Commun, 8, 2017
5VXB
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CRYSTAL STRUCTURE OF CAULOBACTER CRESCENTUS PROXP-ALA AT 1.69 ANGSTROM
分子名称:ProXp-ala
著者Foster, M.P., Musier-Forsyth, K., Nakanishi, K., Ma, X.
登録日2017-05-23
公開日2017-08-09
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Conformational and chemical selection by a trans-acting editing domain.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NQI
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E.COLI 16S RRNA SARCIN-RICIN LOOP CONTAINING A 5-HYDROXYMETHYLCYTOSINE MODIFICATION
分子名称:E.Coli 27-mer SRL RNA
著者Ennifar, E., Micura, R.
登録日2017-04-20
公開日2017-07-26
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (0.851 Å)
主引用文献Synthesis, Thermodynamic Properties, and Crystal Structure of RNA Oligonucleotides Containing 5-Hydroxymethylcytosine.
J. Org. Chem., 82, 2017
5DGE
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COPING WITH PROLINE STALLING: STRUCTURAL BASIS OF HYPUSINE-INDUCED PROTEIN SYNTHESIS BY THE EUKARYOTIC RIBOSOME
分子名称:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
登録日2015-08-27
公開日2017-01-25
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
5TGM
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CRYSTAL STRUCTURE OF THE S.CEREVISIAE 80S RIBOSOME IN COMPLEX WITH THE A-SITE BOUND AMINOACYL-TRNA ANALOG ACCA-PRO
分子名称:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Melnikov, S., Mailliot, J., Yusupov, M.
登録日2016-09-28
公開日2017-01-18
最終更新日2017-01-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
5DGF
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COMPLEX OF YEAST 80S RIBOSOME WITH HYPUSINE-CONTAINING/NON-MODIFIED EIF5A AND/OR A PEPTIDYL-TRNA ANALOG
分子名称:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
登録日2015-08-27
公開日2016-12-14
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
5DGV
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COMPLEX OF YEAST 80S RIBOSOME WITH HYPUSINE-CONTAINING/NON-MODIFIED EIF5A AND/OR A PEPTIDYL-TRNA ANALOG
分子名称:Saccharomyces cerevisiae S288c RDN37-1 miscRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
登録日2015-08-28
公開日2016-12-14
最終更新日2017-03-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
5LYB
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CRYSTAL STRUCTURE OF THE S.CEREVISIAE 80S RIBOSOME IN COMPLEX WITH THE A-SITE BOUND AMINOACYL-TRNA ANALOG ACCPMN
分子名称:18S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Melnikov, S., Mailliot, J.
登録日2016-09-26
公開日2016-11-23
最終更新日2016-12-14
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
5TGA
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CRYSTAL STRUCTURE OF THE S.CEREVISIAE 80S RIBOSOME IN COMPLEX WITH THE A-SITE BOUND AMINOACYL-TRNA ANALOG ACCA-PRO
分子名称:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Melnikov, S., Mailliot, J.
登録日2016-09-27
公開日2016-11-23
最終更新日2016-12-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
5DAT
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COMPLEX OF YEAST 80S RIBOSOME WITH HYPUSINE-CONTAINING EIF5A
分子名称:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
登録日2015-08-20
公開日2016-08-31
最終更新日2018-11-21
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
5K7C
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THE NATIVE STRUCTURE OF NATIVE PISTOL RIBOZYME
分子名称:RNA 47-MER, DNA/RNA 11-MER, MAGNESIUM ION
著者Ren, A., Patel, D.
登録日2016-05-26
公開日2016-07-13
最終更新日2016-08-31
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.
Nat.Chem.Biol., 12, 2016
5K7D
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THE STRUCTURE OF NATIVE PISTOL RIBOZYME, BOUND TO IRIDIUM
分子名称:RNA 47-MER, DNA/RNA 11-MER, IRIDIUM HEXAMMINE ION, ...
著者Ren, A., Patel, D.
登録日2016-05-26
公開日2016-07-13
最終更新日2016-08-31
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.
Nat.Chem.Biol., 12, 2016
5K7E
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THE STRUCTURE OF PISTOL RIBOZYME, SOAKED WITH MN2+
分子名称:RNA 47-MER, DNA/RNA 11-MER, MANGANESE (II) ION
著者Ren, A., Patel, D.
登録日2016-05-26
公開日2016-07-13
最終更新日2016-08-31
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.
Nat.Chem.Biol., 12, 2016
5DC3
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COMPLEX OF YEAST 80S RIBOSOME WITH NON-MODIFIED EIF5A
分子名称:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
登録日2015-08-23
公開日2016-06-01
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome.
J.Mol.Biol., 428, 2016
5D99
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3DW4 REDETERMINED BY DIRECT METHODS STARTING FROM RANDOM PHASE ANGLES
分子名称:RNA (27-MER) hairpin from sarcin-ricin domain of E. coli 23S rRNA, GLYCEROL
著者Mooers, B.H.M.
登録日2015-08-18
公開日2016-04-13
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (0.97 Å)
主引用文献Direct-methods structure determination of a trypanosome RNA-editing substrate fragment with translational pseudosymmetry
Acta Crystallogr.,Sect.D, 72, 2016
4Y27
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E.COLI 23S SARCIN-RICIL LOOP, MODIFIED WITH A 2-ME ON G2661 AND A METHYLPHOSPHONATE ON A2662
分子名称:27-mer SRL RNA
著者Ennifar, E., Micura, R., Fluer, S.
登録日2015-02-09
公開日2015-11-18
実験手法X-RAY DIFFRACTION (0.998 Å)
主引用文献Role of a ribosomal RNA phosphate oxygen during the EF-G-triggered GTP hydrolysis.
Proc.Natl.Acad.Sci.USA, 112, 2015
5DUN
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THE CRYSTAL STRUCTURE OF OME SUBSTITUTED TWISTER RIBOZYME
分子名称:RNA (54-MER), MAGNESIUM ION, POTASSIUM ION
著者Ren, A., Patel, D.J., Micura, R., Rajashankar, K.R.
登録日2015-09-19
公開日2015-10-28
最終更新日2016-01-27
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class.
Angew.Chem.Int.Ed.Engl., 54, 2015
4NXH
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2'-TRIFLUOROMETHYLTHIOURIDINE-MODIFIED E. COLI 23S RRNA SARCIN RICIN LOOP
分子名称:23S ribosomal RNA Sarcin Ricin Loop, GLYCEROL, SULFATE ION
著者Ennifar, E., Micura, R., Kosutic, M.
登録日2013-12-09
公開日2014-12-10
実験手法X-RAY DIFFRACTION (1.158 Å)
主引用文献2'-Trifluoromethylthio-modified RNA: synthesis, X-ray structure, thermodynamic analysis, and applications
To be Published
4RGE
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CRYSTAL STRUCTURE OF THE IN-LINE ALIGNED ENV22 TWISTER RIBOZYME
分子名称:env22 twister ribozyme, MAGNESIUM ION
著者Ren, A., Rajashankar, K.R., Simanshu, D., Patel, D.
登録日2014-09-30
公開日2014-12-03
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme.
Nat Commun, 5, 2014
4RGF
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CRYSTAL STRUCTURE OF THE IN-LINE ALIGNED ENV22 TWISTER RIBOZYME SOAKED WITH MN2+
分子名称:env22 twister ribozyme, MANGANESE (II) ION, POTASSIUM ION, ...
著者Ren, A., Rajashankar, K.R., Simanshu, D., Patel, D.
登録日2014-09-30
公開日2014-12-03
実験手法X-RAY DIFFRACTION (3.2008 Å)
主引用文献In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme.
Nat Commun, 5, 2014
4NLF
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2'-TRIFLUOROMETHYLTHIO-2'-DEOXYCYTIDINE-MODIFIED SRL
分子名称:23S ribosomal RNA Sarcin Ricin Loop, SULFATE ION
著者Ennifar, E., Micura, R., Kosutic, M.
登録日2013-11-14
公開日2014-11-19
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献2'-Trifluoromethylthio-modified RNA: synthesis, X-ray structure, thermodynamic analysis, and applications
To be Published
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