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3KAY
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CRYSTAL STRUCTURE OF ABSCISIC ACID RECEPTOR PYL1
分子名称:Putative uncharacterized protein At5g46790
著者Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Xu, H.E.
登録日2009-10-19
公開日2009-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3KAZ
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CRYSTAL STRUCTURE OF ABSCISIC ACID RECEPTOR PYL2
分子名称:Putative uncharacterized protein At2g26040, 1,3-BUTANEDIOL
著者Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Xu, H.E.
登録日2009-10-19
公開日2009-12-08
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3KB0
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CRYSTAL STRUCTURE OF ABSCISIC ACID-BOUND PYL2
分子名称:Putative uncharacterized protein At2g26040, (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid
著者Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Xu, H.E.
登録日2009-10-19
公開日2009-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3KB3
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CRYSTAL STRUCTURE OF ABSCISIC ACID-BOUND PYL2 IN COMPLEX WITH HAB1
分子名称:Putative uncharacterized protein At2g26040, Protein phosphatase 2C 16, (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ...
著者Zhou, X.E., Melcher, K., Soon, F.-F., Ng, L.-M., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Xu, H.E.
登録日2009-10-20
公開日2009-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3NMH
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CRYSTAL STRUCTURE OF THE ABSCISIC RECEPTOR PYL2 IN COMPLEX WITH PYRABACTIN
分子名称:Abscisic acid receptor PYL2, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
著者Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
登録日2010-06-22
公開日2010-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3NMN
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CRYSTAL STRUCTURE OF PYRABACTIN-BOUND ABSCISIC ACID RECEPTOR PYL1 IN COMPLEX WITH TYPE 2C PROTEIN PHOSPHATASE ABI1
分子名称:Abscisic acid receptor PYL1, Protein phosphatase 2C 56, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, ...
著者Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
登録日2010-06-22
公開日2010-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3NMP
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CRYSTAL STRUCTURE OF THE ABSCISIC RECEPTOR PYL2 MUTANT A93F IN COMPLEX WITH PYRABACTIN
分子名称:Abscisic acid receptor PYL2, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide
著者Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
登録日2010-06-22
公開日2010-08-25
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3NMT
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CRYSTAL STRUCTURE OF PYRABACTIN BOUND ABSCISIC ACID RECEPTOR PYL2 MUTANT A93F IN COMPLEX WITH TYPE 2C PROTEIN PHOSPHATASE HAB1
分子名称:Abscisic acid receptor PYL2, Protein phosphatase 2C 16, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, ...
著者Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
登録日2010-06-22
公開日2010-08-25
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
3NMV
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CRYSTAL STRUCTURE OF PYRABACTIN-BOUND ABSCISIC ACID RECEPTOR PYL2 MUTANT A93F IN COMPLEX WITH TYPE 2C PROTEIN PHOSPHATASE ABI2
分子名称:Abscisic acid receptor PYL2, Protein phosphatase 2C 77, 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, ...
著者Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
登録日2010-06-22
公開日2010-08-25
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification and mechanism of ABA receptor antagonism.
Nat.Struct.Mol.Biol., 17, 2010
5J9K
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CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL TOPLESS DOMAIN (1-209) IN COMPLEX WITH RICE D53 REPRESSOR EAR PEPTIDE MOTIF
分子名称:Protein TPR1, rice D53 peptide 794-808, ZINC ION
著者Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
登録日2016-04-10
公開日2017-07-05
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5JA5
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CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL TOPLESS DOMAIN (1-209) L111A AND L130A MUTANT IN COMPLEX WITH RICE D53 REPRESSOR EAR PEPTIDE MOTIF
分子名称:Protein TPR1, The rice D53 peptide (a.a. 794-808), ZINC ION
著者Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
登録日2016-04-12
公開日2017-07-05
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5JGC
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CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL TOPLESS DOMAIN (1-209) L111A, L130A, L179A AND I195A MUTANT
分子名称:Protein TPR1, ZINC ION
著者Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
登録日2016-04-20
公開日2017-07-05
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
5JHP
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CRYSTAL STRUCTURE OF THE RICE TOPLESS RELATED PROTEIN 2 (TPR2) N-TERMINAL TOPLESS DOMAIN (1-209) L179A AND I195A MUTANT IN COMPLEX WITH RICE D53 REPRESSOR EAR PEPTIDE MOTIF
分子名称:Protein TPR1, The rice D53 EAR peptide (794-808)
著者Ke, J., Ma, H., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
登録日2016-04-21
公開日2017-07-05
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex.
Sci Adv, 3, 2017
4ZWJ
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CRYSTAL STRUCTURE OF RHODOPSIN BOUND TO ARRESTIN BY FEMTOSECOND X-RAY LASER
分子名称:Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin
著者Kang, Y., Zhou, X.E., Gao, X., He, Y., Liu, W., Ishchenko, A., Barty, A., White, T.A., Yefanov, O., Han, G.W., Xu, Q., de Waal, P.W., Ke, J., Tan, M.H.E., Zhang, C., Moeller, A., West, G.M., Pascal, B., Eps, N.V., Caro, L.N., Vishnivetskiy, S.A., Lee, R.J., Suino-Powell, K.M., Gu, X., Pal, K., Ma, J., Zhi, X., Boutet, S., Williams, G.J., Messerschmidt, M., Gati, C., Zatsepin, N.A., Wang, D., James, D., Basu, S., Roy-Chowdhury, S., Conrad, C., Coe, J., Liu, H., Lisova, S., Kupitz, C., Grotjohann, I., Fromme, R., Jiang, Y., Tan, M., Yang, H., Li, J., Wang, M., Zheng, Z., Li, D., Howe, N., Zhao, Y., Standfuss, J., Diederichs, K., Dong, Y., Potter, C.S., Carragher, B., Caffrey, M., Jiang, H., Chapman, H.N., Spence, J.C.H., Fromme, P., Weierstall, U., Ernst, O.P., Katritch, V., Gurevich, V.V., Griffin, P.R., Hubbell, W.L., Stevens, R.C., Cherezov, V., Melcher, K., Xu, H.E., GPCR Network (GPCR)
登録日2015-05-19
公開日2015-07-29
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (3.302 Å)
主引用文献Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Nature, 523, 2015
4P6W
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CRYSTAL STRUCTURE OF MOMETASONE FUROATE-BOUND GLUCOCORTICOID RECEPTOR LIGAND BINDING DOMAIN
分子名称:Glucocorticoid receptor, Nuclear receptor coactivator 2, MOMETASONE FUROATE
著者He, Y., Zhou, X.E., Tolbert, W.D., Powell, K., Melcher, K., Xu, H.E.
登録日2014-03-25
公開日2014-04-16
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.951 Å)
主引用文献Structures and mechanism for the design of highly potent glucocorticoids.
Cell Res., 24, 2014
4P6X
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CRYSTAL STRUCTURE OF CORTISOL-BOUND GLUCOCORTICOID RECEPTOR LIGAND BINDING DOMAIN
分子名称:Glucocorticoid receptor, Nuclear receptor coactivator 2, (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
著者He, Y., Zhou, X.E., Tolbert, W.D., Powell, K., Melcher, K., Xu, H.E.
登録日2014-03-25
公開日2014-04-16
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures and mechanism for the design of highly potent glucocorticoids.
Cell Res., 24, 2014
5TO5
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STRUCTURE OF THE TPR OLIGOMERIZATION DOMAIN
分子名称:Nucleoprotein TPR
著者Pal, K., Xu, Q., Zhou, X.E., Melcher, K., Xu, H.E.
登録日2016-10-16
公開日2017-10-18
最終更新日2019-05-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis of TPR-Mediated Oligomerization and Activation of Oncogenic Fusion Kinases.
Structure, 25, 2017
5TO6
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STRUCTURE OF THE TPR OLIGOMERIZATION DOMAIN
分子名称:Nucleoprotein TPR
著者Pal, K., Bandyopadhyay, A., Xu, Q., Zhou, X.E., Melcher, K., Xu, H.E.
登録日2016-10-16
公開日2017-10-18
最終更新日2019-05-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis of TPR-Mediated Oligomerization and Activation of Oncogenic Fusion Kinases.
Structure, 25, 2017
5TO7
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STRUCTURE OF THE TPR OLIGOMERIZATION DOMAIN
分子名称:Nucleoprotein TPR
著者Pal, K., Xu, Q., Zhou, X.E., Melcher, K., Xu, H.E.
登録日2016-10-16
公開日2017-10-18
最終更新日2019-05-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis of TPR-Mediated Oligomerization and Activation of Oncogenic Fusion Kinases.
Structure, 25, 2017
5TVB
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STRUCTURE OF THE TPR OLIGOMERIZATION DOMAIN
分子名称:Nucleoprotein TPR
著者Pal, K., Xu, Q., Zhou, X.E., Melcher, K., Xu, H.E.
登録日2016-11-08
公開日2017-09-20
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Basis of TPR-Mediated Oligomerization and Activation of Oncogenic Fusion Kinases.
Structure, 25, 2017
5TWO
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PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH A NOVEL SELECTIVELY PPAR GAMMA-MODULATING LIGAND VSP-51
分子名称:Peroxisome proliferator-activated receptor gamma, PRO-SER-LEU-LEU-LYS-LYS-LEU-LEU-LEU-ALA-PRO, N-benzyl-1-[(4-chloro-3-fluorophenyl)methyl]-1H-indole-5-carboxamide
著者Yi, W., Shi, J., Zhao, G., Zhou, X.E., Suino-Powell, K., Melcher, K., Xu, H.E.
登録日2016-11-14
公開日2017-02-08
最終更新日2018-10-24
実験手法X-RAY DIFFRACTION (1.927 Å)
主引用文献Identification of a novel selective PPAR gamma ligand with a unique binding mode and improved therapeutic profile in vitro.
Sci Rep, 7, 2017
5W0P
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CRYSTAL STRUCTURE OF RHODOPSIN BOUND TO VISUAL ARRESTIN DETERMINED BY X-RAY FREE ELECTRON LASER
分子名称:Endolysin,Rhodopsin,S-arrestin, N-ACETYL-D-GLUCOSAMINE
著者Zhou, X.E., He, Y., de Waal, P.W., Gao, X., Kang, Y., Van Eps, N., Yin, Y., Pal, K., Goswami, D., White, T.A., Barty, A., Latorraca, N.R., Chapman, H.N., Hubbell, W.L., Dror, R.O., Stevens, R.C., Cherezov, V., Gurevich, V.V., Griffin, P.R., Ernst, O.P., Melcher, K., Xu, H.E.
登録日2017-05-31
公開日2017-08-09
最終更新日2018-11-21
実験手法X-RAY DIFFRACTION (3.013 Å)
主引用文献Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.
Cell, 170, 2017
5IZQ
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CRYSTAL STRUCTURE OF HUMAN FOLATE RECEPTOR ALPHA IN COMPLEX WITH NOVEL ANTIFOLATE AGF183
分子名称:Folate receptor alpha, N-(4-{[2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)ethyl]amino}benzene-1-carbonyl)-L-glutamic acid
著者Ke, J., Gu, X., Brunzelle, J.S., Xu, H.E., Melcher, K.
登録日2016-03-25
公開日2016-08-10
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor alpha and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.
J.Med.Chem., 59, 2016
5T0F
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CRYSTAL STRUCTURE OF THE MYC3 N-TERMINAL DOMAIN [44-242] IN COMPLEX WITH JAZ10 CMID DOMAIN [16-58] FROM ARABIDOPSIS
分子名称:Transcription factor MYC3, Protein TIFY 9
著者Ke, J., Zhang, F., Brunzelle, J.S., He, S.Y., Xu, H.E., Melcher, K.
登録日2016-08-16
公開日2017-01-25
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into alternative splicing-mediated desensitization of jasmonate signaling.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5T0Q
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CRYSTAL STRUCTURE OF THE MYC3 N-TERMINAL DOMAIN [44-242] IN COMPLEX WITH JAZ10 JAS DOMAIN [166-192] FROM ARABIDOPSIS
分子名称:Transcription factor MYC3, Protein TIFY 9
著者Ke, J., Zhang, F., Brunzelle, J.S., He, S.Y., Xu, H.E., Melcher, K.
登録日2016-08-16
公開日2017-01-25
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural insights into alternative splicing-mediated desensitization of jasmonate signaling.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017