Author results

2K39
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RECOGNITION DYNAMICS UP TO MICROSECONDS REVEALED FROM RDC DERIVED UBIQUITIN ENSEMBLE IN SOLUTION
分子名称:Ubiquitin
著者Lange, O.F., Lakomek, N.A., Fares, C., Schroder, G., Walter, K., Becker, S., Meiler, J., Grubmuller, H., Griesinger, C., de Groot, B.L.
登録日2008-04-25
公開日2008-06-24
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution.
Science, 320, 2008
2K21
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NMR STRUCTURE OF HUMAN KCNE1 IN LMPG MICELLES AT PH 6.0 AND 40 DEGREE C
分子名称:Potassium voltage-gated channel subfamily E member
著者Kang, C., Tian, C., Sonnichsen, F.D., Smith, J.A., Meiler, J., George, A.L., Vanoye, C.G., Sanders, C.R., Kim, H.
登録日2008-03-19
公開日2008-12-09
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel.
Biochemistry, 47, 2008
2KN5
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A CORRESPONDENCE BETWEEN SOLUTION-STATE DYNAMICS OF AN INDIVIDUAL PROTEIN AND THE SEQUENCE AND CONFORMATIONAL DIVERSITY OF ITS FAMILY
分子名称:Ubiquitin
著者Friedland, G.D.
登録日2009-08-14
公開日2009-11-17
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A correspondence between solution-state dynamics of an individual protein and the sequence and conformational diversity of its family.
PLOS COMPUT.BIOL., 5, 2009
3MF6
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COMPUTATIONALLY DESIGNED ENDO-1,4-BETA-XYLANASE
分子名称:Endo-1,4-beta-xylanase, SULFATE ION
著者Morin, A., Harp, J.M.
登録日2010-04-01
公開日2010-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Computational design of an endo-1,4-{beta}-xylanase ligand binding site.
Protein Eng.Des.Sel., 24, 2011
3MF9
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COMPUTATIONALLY DESIGNED ENDO-1,4-BETA-XYLANASE
分子名称:Endo-1,4-beta-xylanase, SULFATE ION
著者Morin, A., Harp, J.M.
登録日2010-04-01
公開日2010-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Computational design of an endo-1,4-{beta}-xylanase ligand binding site.
Protein Eng.Des.Sel., 24, 2011
3MFA
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COMPUTATIONALLY DESIGNED ENDO-1,4-BETA-XYLANASE
分子名称:Endo-1,4-beta-xylanase, SULFATE ION
著者Morin, A., Harp, J.M.
登録日2010-04-01
公開日2010-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Computational design of an endo-1,4-{beta}-xylanase ligand binding site.
Protein Eng.Des.Sel., 24, 2011
3MFC
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COMPUTATIONALLY DESIGNED END0-1,4-BETA,XYLANASE
分子名称:Endo-1,4-beta-xylanase, SULFATE ION
著者Morin, A., Harp, J.M.
登録日2010-04-01
公開日2010-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Computational design of an endo-1,4-{beta}-xylanase ligand binding site.
Protein Eng.Des.Sel., 24, 2011
3TDM
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COMPUTATIONALLY DESIGNED TIM-BARREL PROTEIN, HALFFLR
分子名称:Computationally designed two-fold symmetric TIM-barrel protein, FLR (half molecule), PHOSPHATE ION
著者Harp, J.M., Fortenberry, C., Bowman, E., Profitt, W., Dorr, B., Mizoue, L.
登録日2011-08-11
公開日2011-11-16
最終更新日2011-11-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Exploring symmetry as an avenue to the computational design of large protein domains.
J.Am.Chem.Soc., 133, 2011
3TDN
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COMPUTATIONALLY DESIGNED TWO-FOLD SYMMETRIC TIM-BARREL PROTEIN, FLR
分子名称:FLR SYMMETRIC ALPHA-BETA TIM BARREL
著者Harp, J.M., Fortenberry, C., Bowman, E., Profitt, W., Dorr, B., Mizoue, L., Meiler, J.
登録日2011-08-11
公開日2011-11-16
最終更新日2011-11-23
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Exploring symmetry as an avenue to the computational design of large protein domains.
J.Am.Chem.Soc., 133, 2011
2LLE
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COMPUTATIONAL DESIGN OF AN EIGHT-STRANDED (BETA/ALPHA)-BARREL FROM FRAGMENTS OF DIFFERENT FOLDS
分子名称:Chemotaxis protein CheY, Imidazole glycerol phosphate synthase subunit HisF chimera
著者Coles, M., Truffault, V., Eisenbeis, S., Proffitt, W., Meiler, J., Hocker, B.
登録日2011-11-07
公開日2012-03-21
実験手法SOLUTION NMR
主引用文献Potential of fragment recombination for rational design of proteins.
J.Am.Chem.Soc., 134, 2012
4HFW
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ANTI ROTAVIRUS ANTIBODY
分子名称:6-26 Fab Light chain, 6-26 Fab Heavy chain, SULFATE ION
著者Spiller, B.W., Aiyegbo, M., Crowe, J.E.
登録日2012-10-05
公開日2013-05-29
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Human Rotavirus VP6-Specific Antibodies Mediate Intracellular Neutralization by Binding to a Quaternary Structure in the Transcriptional Pore.
Plos One, 8, 2013
4GSD
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H5.3 FAB STRUCTURE
分子名称:H5.3 Fab Light Chain, H5.3 Fab Heavy Chain
著者Spiller, B.W., Winarski, K.L.
登録日2012-08-27
公開日2013-08-21
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses.
J.Clin.Invest., 123, 2013
4OR2
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HUMAN CLASS C G PROTEIN-COUPLED METABOTROPIC GLUTAMATE RECEPTOR 1 IN COMPLEX WITH A NEGATIVE ALLOSTERIC MODULATOR
分子名称:Soluble cytochrome b562, Metabotropic glutamate receptor 1, 4-fluoro-N-methyl-N-{4-[6-(propan-2-ylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl}benzamide, ...
著者Wu, H., Wang, C., Gregory, K.J., Han, G.W., Cho, H.P., Xia, Y., Niswender, C.M., Katritch, V., Cherezov, V., Conn, P.J., Stevens, R.C., GPCR Network (GPCR)
登録日2014-02-10
公開日2014-03-19
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator
Science, 344, 2014
4PAM
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A CONSERVED PHENYLALANINE AS RELAY BETWEEN THE 5 HELIX AND THE GDP BINDING REGION OF HETEROTRIMERIC G PROTEIN
分子名称:Guanine nucleotide-binding protein G(i) subunit alpha-1, GUANOSINE-5'-DIPHOSPHATE, SULFITE ION, ...
著者Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
登録日2014-04-09
公開日2014-07-30
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.
J.Biol.Chem., 289, 2014
4PAN
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A CONSERVED PHENYLALANINE AS RELAY BETWEEN THE 5 HELIX AND THE GDP BINDING REGION OF HETEROTRIMERIC G PROTEIN
分子名称:Guanine nucleotide-binding protein G(i) subunit alpha-1, GUANOSINE-5'-DIPHOSPHATE, SULFITE ION, ...
著者Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
登録日2014-04-09
公開日2014-07-30
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.
J.Biol.Chem., 289, 2014
4PAO
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A CONSERVED PHENYLALANINE AS RELAY BETWEEN THE 5 HELIX AND THE GDP BINDING REGION OF HETEROTRIMERIC G PROTEIN
分子名称:Guanine nucleotide-binding protein G(i) subunit alpha-1, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION
著者Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
登録日2014-04-09
公開日2014-07-30
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.
J.Biol.Chem., 289, 2014
4PAQ
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A CONSERVED PHENYLALANINE AS RELAY BETWEEN THE 5 HELIX AND THE GDP BINDING REGION OF HETEROTRIMERIC G PROTEIN
分子名称:Guanine nucleotide-binding protein G(i) subunit alpha-1, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION
著者Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
登録日2014-04-09
公開日2014-07-30
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.
J.Biol.Chem., 289, 2014
4YAQ
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CRYSTAL STRUCTURE OF A COMPUTATIONALLY OPTIMIZED PG9 MUTANT
分子名称:PG9_N100FY Fab heavy chain, PG9_N100FY Light Chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Murrell, S., Julien, J.P., Wilson, I.A.
登録日2015-02-17
公開日2015-06-03
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.
J.Clin.Invest., 125, 2015
4ZWQ
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CRYSTAL STRUCTURE OF THE BACTERIOPHAGE T4 RECOMBINATION MEDIATOR PROTEIN UVSY, LATTICE TYPE I
分子名称:Recombination protein uvsY
著者Gajewski, S., White, S.W.
登録日2015-05-19
公開日2016-03-02
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献Structure and mechanism of the phage T4 recombination mediator protein UvsY.
Proc.Natl.Acad.Sci.USA, 113, 2016
4ZWR
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CRYSTAL STRUCTURE OF THE BACTERIOPHAGE T4 RECOMBINATION MEDIATOR PROTEIN UVSY, LATTICE TYPE II
分子名称:Recombination protein uvsY
著者Gajewski, S., White, S.W.
登録日2015-05-19
公開日2016-03-02
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (3.3857 Å)
主引用文献Structure and mechanism of the phage T4 recombination mediator protein UvsY.
Proc.Natl.Acad.Sci.USA, 113, 2016
4ZWS
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CRYSTAL STRUCTURE OF THE BACTERIOPHAGE T4 RECOMBINATION MEDIATOR PROTEIN UVSY, LATTICE TYPE III
分子名称:Recombination protein uvsY
著者Gajewski, S., White, S.W.
登録日2015-05-19
公開日2016-03-02
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and mechanism of the phage T4 recombination mediator protein UvsY.
Proc.Natl.Acad.Sci.USA, 113, 2016
4ZWT
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CRYSTAL STRUCTURE OF THE BACTERIOPHAGE T4 RECOMBINATION MEDIATOR PROTEIN UVSY, LATTICE TYPE IV
分子名称:Recombination protein uvsY
著者Gajewski, S., White, S.W.
登録日2015-05-19
公開日2016-03-02
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Structure and mechanism of the phage T4 recombination mediator protein UvsY.
Proc.Natl.Acad.Sci.USA, 113, 2016
4ZV6
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CRYSTAL STRUCTURE OF THE ARTIFICIAL ALPHAREP-7 OCTARELLINV.1 COMPLEX
分子名称:AlphaRep-7, Octarellin V.1
著者Figueroa, M., Sleutel, M., Urvoas, A., Valerio-Lepiniec, M., Minard, P., Martial, J.A., van de Weerdt, C.
登録日2015-05-18
公開日2016-05-25
最終更新日2016-06-08
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
J.Struct.Biol., 195, 2016
5BOP
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CRYSTAL STRUCTURE OF THE ARTIFICIAL NANOBODY OCTARELLINV.1 COMPLEX
分子名称:Nanobody, Octarellin V.1
著者Figueroa, M., Sleutel, M., Pardon, E., Steyaert, J., Martial, J.A., van de Weerdt, C.
登録日2015-05-27
公開日2016-05-25
最終更新日2016-06-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools.
J.Struct.Biol., 195, 2016
5KDL
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CRYSTAL STRUCTURE OF THE 4 ALANINE INSERTION VARIANT OF THE GI ALPHA1 SUBUNIT BOUND TO GTPGAMMAS
分子名称:Guanine nucleotide-binding protein G(i) subunit alpha-1, MAGNESIUM ION, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE
著者Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
登録日2016-06-08
公開日2016-08-03
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.665 Å)
主引用文献A Conserved Hydrophobic Core in G alpha i1 Regulates G Protein Activation and Release from Activated Receptor.
J.Biol.Chem., 291, 2016
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