Author results

3P4A
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2'FLUORO MODIFIED RNA OCTAMER FA2U2
分子名称:2'Fluoro modified RNA 8-MER, STRONTIUM ION, MAGNESIUM ION
著者Manoharan, M., Akinc, A., Pandey, R.K., Qin, J., Hadwiger, P., John, M., Mills, K., Charisse, K., Maier, M.A., Nechev, L., Greene, E.M., Pallan, P.S., Rozners, E., Rajeev, K.G., Egli, M.
登録日2010-10-06
公開日2011-01-05
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA.
Nucleic Acids Res., 39, 2011
1D8Y
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CRYSTAL STRUCTURE OF THE COMPLEX OF DNA POLYMERASE I KLENOW FRAGMENT WITH DNA
分子名称:D(T)19 OLIGOMER, DNA POLYMERASE I, ZINC ION, ...
著者Teplova, M., Wallace, S.T., Tereshko, V., Minasov, G., Simons, A.M., Cook, P.D., Manoharan, M., Egli, M.
登録日1999-10-26
公開日1999-12-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural origins of the exonuclease resistance of a zwitterionic RNA.
Proc.Natl.Acad.Sci.USA, 96, 1999
1D9D
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CRYSTALL STRUCTURE OF THE COMPLEX OF DNA POLYMERASE I KLENOW FRAGMENT WITH SHORT DNA FRAGMENT CARRYING 2'-0-AMINOPROPYL-RNA MODIFICATIONS 5'-D(TCG)-AP(AUC)-3'
分子名称:5'-D(*TP*CP*GP)-R(AP*(U31)P*(C31))-3', DNA POLYMERASE I, ZINC ION, ...
著者Teplova, M., Wallace, S.T., Tereshko, V., Minasov, G., Simons, A.M., Cook, P.D., Manoharan, M., Egli, M.
登録日1999-10-27
公開日1999-12-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structural origins of the exonuclease resistance of a zwitterionic RNA.
Proc.Natl.Acad.Sci.USA, 96, 1999
1D9F
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CRYSTAL STRUCTURE OF THE COMPLEX OF DNA POLYMERASE I KLENOW FRAGMENT WITH DNA TETRAMER CARRYING 2'-O-(3-AMINOPROPYL)-RNA MODIFICATION 5'-D(TT)-AP(U)-D(T)-3'
分子名称:DNA/RNA (5'-D(*TP*TP)-R(*(U31)P)-D(*T)-3'), DNA POLYMERASE I, ZINC ION, ...
著者Teplova, M., Wallace, S.T., Tereshko, V., Minasov, G., Simons, A.M., Cook, P.D., Manoharan, M., Egli, M.
登録日1999-10-27
公開日1999-12-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural origins of the exonuclease resistance of a zwitterionic RNA.
Proc.Natl.Acad.Sci.USA, 96, 1999
1D9H
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STRUCTURAL ORIGINS OF THE EXONUCLEASE RESISTANCE OF A ZWITTERIONIC RNA
分子名称:DNA/RNA (5'-D(*GP*CP*GP*TP*AP)-R(*(U31)P)-D(*AP*CP*GP*C)-3')
著者Teplova, M., Wallace, S.T., Tereshko, V., Minasov, G., Simons, A.M., Cook, P.D., Manoharan, M., Egli, M.
登録日1999-10-27
公開日1999-12-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural origins of the exonuclease resistance of a zwitterionic RNA
Proc.Natl.Acad.Sci.USA, 96, 1999
1DPL
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A-DNA DECAMER GCGTA(T23)TACGC WITH INCORPORATED 2'-METHOXY-3'-METHYLENEPHOSPHATE-THYMIDINE
分子名称:5'-D(*GP*CP*GP*TP*AP*(T23)P*AP*CP*GP*C)-3', MAGNESIUM ION, SPERMINE
著者Egli, M., Tereshko, V., Teplova, M., Minasov, G., Joachimiak, A., Sanishvili, R., Weeks, C.M., Miller, R., Maier, M.A., An, H., Dan Cook, P., Manoharan, M.
登録日1999-12-27
公開日2000-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (0.83 Å)
主引用文献X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.
Biopolymers, 48, 1998
1DPN
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B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE
分子名称:DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
著者Egli, M., Tereshko, V., Teplova, M., Minasov, G., Joachimiak, A., Sanishvili, R., Weeks, C.M., Miller, R., Maier, M.A., An, H., Dan Cook, P., Manoharan, M.
登録日1999-12-27
公開日2000-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.
Biopolymers, 48, 1998
1I0F
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1.6 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-AMINOOXYETHYL THYMINE IN PLACE OF T6, BA-FORM
分子名称:5'-D(*GP*CP*GP*TP*AP*(127)P*AP*CP*GP*C)-3', BARIUM ION
著者Tereshko, V., Wilds, C.J., Minasov, G., Prakash, T.P., Maier, M.A., Howard, A., Wawrzak, Z., Manoharan, M., Egli, M.
登録日2001-01-29
公開日2001-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.
Nucleic Acids Res., 29, 2001
1I0G
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1.45 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-FLUOROETHYL THYMINE IN PLACE OF T6, MEDIUM NA-SALT
分子名称:5'-D(*GP*CP*GP*TP*AP*(125)P*AP*CP*GP*C)-3', SODIUM ION
著者Tereshko, V., Wilds, C.J., Minasov, G., Prakash, T.P., Maier, M.A., Howard, A., Wawrzak, Z., Manoharan, M., Egli, M.
登録日2001-01-29
公開日2001-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.
Nucleic Acids Res., 29, 2001
1I0J
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1.06 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-3'-METHYLENEPHOSPHONATE (T23) THYMINE IN PLACE OF T6, HIGH CS-SALT
分子名称:5'-D(*GP*CP*GP*TP*AP*(T23)P*AP*CP*GP*C)-3', CESIUM ION
著者Tereshko, V., Wilds, C.J., Minasov, G., Prakash, T.P., Maier, M.A., Howard, A., Wawrzak, Z., Manoharan, M., Egli, M.
登録日2001-01-29
公開日2001-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.
Nucleic Acids Res., 29, 2001
1I0K
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1.05 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)] THYMINE IN PLACE OF T6, MEDIUM CS-SALT
分子名称:5'-D(*GP*CP*GP*TP*AP*(126)P*AP*CP*GP*C)-3', CESIUM ION
著者Tereshko, V., Wilds, C.J., Minasov, G., Prakash, T.P., Maier, M.A., Howard, A., Wawrzak, Z., Manoharan, M., Egli, M.
登録日2001-01-29
公開日2001-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.
Nucleic Acids Res., 29, 2001
1I0M
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1.05 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-FLUOROETHYL THYMINE IN PLACE OF T6, HIGH RB-SALT
分子名称:5'-D(*GP*CP*GP*TP*AP*(125)P*AP*CP*GP*C)-3', RUBIDIUM ION
著者Tereshko, V., Wilds, C.J., Minasov, G., Prakash, T.P., Maier, M.A., Howard, A., Wawrzak, Z., Manoharan, M., Egli, M.
登録日2001-01-29
公開日2001-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.
Nucleic Acids Res., 29, 2001
1I0N
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1.3 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)] THYMINE IN PLACE OF T6, MEDIUM RB-SALT
分子名称:5'-D(*GP*CP*GP*TP*AP*(126)P*AP*CP*GP*C)-3', RUBIDIUM ION
著者Tereshko, V., Wilds, C.J., Minasov, G., Prakash, T.P., Maier, M.A., Howard, A., Wawrzak, Z., Manoharan, M., Egli, M.
登録日2001-01-29
公開日2001-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.
Nucleic Acids Res., 29, 2001
1I0O
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1.6 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-3'-METHYLENEPHOSPHONATE THYMINE IN PLACE OF T6, HIGH K-SALT
分子名称:5'-D(*GP*CP*GP*TP*AP*(T23)P*AP*CP*GP*C)-3', POTASSIUM ION
著者Tereshko, V., Wilds, C.J., Minasov, G., Prakash, T.P., Maier, M.A., Howard, A., Wawrzak, Z., Manoharan, M., Egli, M.
登録日2001-01-29
公開日2001-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments
Nucleic Acids Res., 29, 2001
1I0P
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1.3 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)], MEDIUM K-SALT
分子名称:5'-D(*GP*CP*GP*TP*AP*(126)P*AP*CP*GP*C)-3', POTASSIUM ION
著者Tereshko, V., Wilds, C.J., Minasov, G., Prakash, T.P., Maier, M.A., Howard, A., Wawrzak, Z., Manoharan, M., Egli, M.
登録日2001-01-29
公開日2001-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.
Nucleic Acids Res., 29, 2001
1I0Q
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1.3 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)] THYMINE IN PLACE OF T6, MEDIUM NA-SALT
分子名称:5'-D(*GP*CP*GP*TP*AP*(126)P*AP*CP*GP*C)-3', SODIUM ION
著者Tereshko, V., Wilds, C.J., Minasov, G., Prakash, T.P., Maier, M.A., Howard, A., Wawrzak, Z., Manoharan, M., Egli, M.
登録日2001-01-29
公開日2001-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.
Nucleic Acids Res., 29, 2001
1I0T
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0.6 A STRUCTURE OF Z-DNA CGCGCG
分子名称:5'-D(*CP*GP*CP*GP*CP*G)-3', SPERMINE
著者Tereshko, V., Wilds, C.J., Minasov, G., Prakash, T.P., Maier, M.A., Howard, A., Wawrzak, Z., Manoharan, M., Egli, M.
登録日2001-01-29
公開日2001-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (0.6 Å)
主引用文献Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.
Nucleic Acids Res., 29, 2001
1KGK
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DIRECT OBSERVATION OF A CYTOSINE ANALOG THAT FORMS FIVE HYDROGEN BONDS TO GUANOSINE; GUANYL G-CLAMP
分子名称:5'-D(*GP*(GCK)P*GP*TP*AP*TP*AP*CP*GP*C)-3', METHOXY-ETHOXYL, SPERMINE (FULLY PROTONATED FORM)
著者Wilds, C.J., Maier, M.A., Tereshko, V., Manoharan, M., Egli, M.
登録日2001-11-27
公開日2001-12-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Direct Observation of a Cytosine Analogue that Forms Five Hydrogen Bonds to Guanosine: Guanidino G-Clamp
Angew.Chem.Int.Ed.Engl., 41, 2002
1MLX
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CRYSTAL STRUCTURE ANALYSIS OF A 2'-O-[2-(METHYLTHIO)-ETHYL]-MODIFIED OLIGODEOXYNUCLEOTIDE DUPLEX
分子名称:5'-D(*GP*CP*GP*TP*AP*SMTP*AP*CP*GP*C)-3'
著者Prakash, T.P., Manoharan, M., Kawasaki, A.M., Fraser, A.S., Lesnik, E.A., Sioufi, N., Leeds, J.M., Teplova, M., Egli, M.
登録日2002-08-31
公開日2002-12-04
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献2'-O-[2-(Methylthio)ethyl]-Modified Oligonucleotide: An Analogue of 2'-O-[2-(Methoxy)-ethyl]-Modified Oligonucleotide with Improved Protein Binding Properties and High Binding Affinity to Target RNA
Biochemistry, 41, 2002
1NZG
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CRYSTAL STRUCTURE OF A-DNA DECAMER GCGTA(3ME)ACGC, WITH A MODIFIED 5-METHYLURIDINE
分子名称:5'-D(*GP*CP*GP*TP*AP*(3ME)P*AP*CP*GP*C)-3'
著者Prhavc, M., Prakash, T.P., Minasov, G., Egli, M., Manoharan, M.
登録日2003-02-17
公開日2003-08-26
最終更新日2011-11-02
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modified oligonucleotides: symbiosis of charge interaction factors and stereoelectronic effects
Org.Lett., 5, 2003
1R3G
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1.16A X-RAY STRUCTURE OF THE SYNTHETIC DNA FRAGMENT WITH THE INCORPORATED 2'-O-[(2-GUANIDINIUM)ETHYL]-5-METHYLURIDINE RESIDUES
分子名称:5'-D(*GP*CP*GP*TP*AP*(GMU)P*AP*CP*GP*C)-3'), MAGNESIUM ION
著者Prakash, T.P., Puschl, A., Lesnik, E., Tereshko, V., Egli, M., Manoharan, M.
登録日2003-10-01
公開日2003-10-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献2'-O-[2-(Guanidinium)ethyl]-Modified Oligonucleotides: Stabilizing Effect on Duplex and Triplex Structures.
Org.Lett., 6, 2004
1XUW
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STRUCTURAL RATIONALIZATION OF A LARGE DIFFERENCE IN RNA AFFINITY DESPITE A SMALL DIFFERENCE IN CHEMISTRY BETWEEN TWO 2'-O-MODIFIED NUCLEIC ACID ANALOGS
分子名称:DNA (5'-D(*GP*CP*GP*TP*AP*(NMT)P*AP*CP*GP*C)-3')
著者Pattanayek, R., Sethaphong, L., Pan, C., Prhavc, M., Prakash, T.P., Manoharan, M., Egli, M.
登録日2004-10-26
公開日2004-12-14
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues.
J.Am.Chem.Soc., 126, 2004
1XUX
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STRUCTURAL RATIONALIZATION OF A LARGE DIFFERENCE IN RNA AFFINITY DESPITE A SMALL DIFFERENCE IN CHEMISTRY BETWEEN TWO 2'-O-MODIFIED NUCLEIC ACID ANALOGS
分子名称:DNA (5'-D(*GP*CP*GP*TP*AP*(NMS)P*AP*CP*GP*C)-3')
著者Pattanayek, R., Sethaphong, L., Pan, C., Prhavc, M., Prakash, T.P., Manoharan, M., Egli, M.
登録日2004-10-26
公開日2004-12-14
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues.
J.Am.Chem.Soc., 126, 2004
1Y7F
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CRYSTAL STRUCTURE OF THE A-DNA GCGTAT*CGC WITH A 2'-O-[2-[HYDROXY(METHYLENEAMINO)OXY]ETHYL] THYMIDINE (T*)
分子名称:5'-D(*GP*CP*GP*TP*AP*(2NT)P*AP*CP*GP*C)-3'), BARIUM ION
著者Egli, M., Minasov, G., Tereshko, V., Pallan, P.S., Teplova, M., Inamati, G.B., Lesnik, E.A., Owens, S.R., Ross, B.S., Prakash, T.P., Manoharan, M.
登録日2004-12-08
公開日2005-06-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
1Y84
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CRYSTAL STRUCTURE OF THE A-DNA GCGTAT*CGC WITH A 2'-O-[2-(IMIDAZOLYL)ETHYL] THYMIDINE (T*)
分子名称:5'-D(*GP*CP*GP*TP*AP*(EIT)P*AP*CP*GP*C)-3', MAGNESIUM ION, SPERMINE
著者Egli, M., Minasov, G., Tereshko, V., Pallan, P.S., Teplova, M., Inamati, G.B., Lesnik, E.A., Owens, S.R., Ross, B.S., Prakash, T.P., Manoharan, M.
登録日2004-12-10
公開日2005-06-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
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