Author results

3QG6
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STRUCTURAL BASIS FOR LIGAND RECOGNITION AND DISCRIMINATION OF A QUORUM QUENCHING ANTIBODY
分子名称:AP4-24H11 Light Chain, AP4-24H11 Heavy Chain, Agr autoinducing peptide, ...
著者Kirchdoerfer, R.N., Janda, J.D., Kaufmann, G.F., Wilson, I.A.
登録日2011-01-24
公開日2011-03-23
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody.
J.Biol.Chem., 286, 2011
3TWI
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VARIABLE LYMPHOCYTE RECEPTOR RECOGNITION OF THE IMMUNODOMINANT GLYCOPROTEIN OF BACILLUS ANTHRACIS SPORES
分子名称:BclA protein, Variable lymphocyte receptor B, GLYCEROL
著者Kirchdoerfer, R.N., Herrin, B.R., Han, B.W., Turnbough Jr., C.L., Cooper, M.D., Wilson, I.A.
登録日2011-09-21
公開日2012-03-14
最終更新日2012-03-28
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores.
Structure, 20, 2012
3TYJ
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BACILLUS COLLAGEN-LIKE PROTEIN OF ANTHRACIS P159S MUTANT
分子名称:BclA protein
著者Kirchdoerfer, R.N., Herrin, B.R., Han, B.W., Turnbough Jr., C.L., Cooper, M.D., Wilson, I.A.
登録日2011-09-26
公開日2012-03-14
最終更新日2012-03-28
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Variable Lymphocyte Receptor Recognition of the Immunodominant Glycoprotein of Bacillus anthracis Spores.
Structure, 20, 2012
4ZTA
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EBOLA VIRUS NUCLEOPROTEIN BOUND TO VP35 CHAPERONING PEPTIDE I212121
分子名称:Polymerase cofactor VP35,Nucleoprotein
著者Kirchdoerfer, R.N., Abelson, D.M., Saphire, E.O.
登録日2015-05-14
公開日2015-05-27
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ebola virus nucleoprotein bound to VP35 chaperoning peptide I212121
to be published
4ZTG
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EBOLA VIRUS NUCLEOPROTEIN BOUND TO VP35 CHAPERONING PEPTIDE P22121
分子名称:Polymerase cofactor VP35,Nucleoprotein fusion protein
著者Kirchdoerfer, R.N., Abelson, D.M., Saphire, E.O.
登録日2015-05-14
公開日2015-05-27
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Ebola virus nucleoprotein bound to VP35 chaperoning peptide P22121
to be published
4ZTI
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EBOLA VIRUS NUCLEOPROTEIN BOUND TO VP35 CHAPERONING PEPTIDE P212121
分子名称:Polymerase cofactor VP35,Nucleoprotein
著者Kirchdoerfer, R.N., Abelson, D.M., Saphire, E.O.
登録日2015-05-14
公開日2015-05-27
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ebola virus nucleoprotein bound to VP35 chaperoning peptide P212121
to be published
5I08
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PREFUSION STRUCTURE OF A HUMAN CORONAVIRUS SPIKE PROTEIN
分子名称:Spike glycoprotein, envelope glycoprotein chimera
著者Kirchdoerfer, R.N., Cottrell, C.A., Wang, N., Pallesen, J., Yassine, H.M., Turner, H.L., Corbett, K.S., Graham, B.S., McLellan, J.S., Ward, A.B.
登録日2016-02-03
公開日2016-03-02
最終更新日2016-04-13
実験手法ELECTRON MICROSCOPY (4.04 Å)
主引用文献Pre-fusion structure of a human coronavirus spike protein.
Nature, 531, 2016
5T3T
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EBOLA VIRUS VP30 CTD BOUND TO NUCLEOPROTEIN
分子名称:Fusion protein of Nucleoprotein and Minor nucleoprotein VP30, SULFATE ION
著者Kirchdoerfer, R.N., Moyer, C.L., Abelson, D.M., Saphire, E.O.
登録日2016-08-26
公開日2016-09-28
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Ebola Virus VP30-NP Interaction Is a Regulator of Viral RNA Synthesis.
Plos Pathog., 12, 2016
6CRV
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, C3 SYMMETRY
分子名称:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
著者Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
登録日2018-03-19
公開日2018-04-11
最終更新日2019-02-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRW
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, SINGLE UPWARDS S1 CTD CONFORMATION
分子名称:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
登録日2018-03-19
公開日2018-04-11
最終更新日2019-02-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRX
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, TWO S1 CTDS IN THE UPWARDS CONFORMATION
分子名称:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
登録日2018-03-19
公開日2018-04-11
最終更新日2019-02-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRZ
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SARS SPIKE GLYCOPROTEIN, TRYPSIN-CLEAVED, STABILIZED VARIANT, C3 SYMMETRY
分子名称:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
登録日2018-03-19
公開日2018-04-11
最終更新日2019-02-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CS0
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SARS SPIKE GLYCOPROTEIN, TRYPSIN-CLEAVED, STABILIZED VARIANT, ONE S1 CTD IN AN UPWARDS CONFORMATION
分子名称:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
登録日2018-03-19
公開日2018-04-11
最終更新日2019-02-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CS1
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SARS SPIKE GLYCOPROTEIN, TRYPSIN-CLEAVED, STABILIZED VARIANT, TWO S1 CTDS IN AN UPWARDS CONFORMATION
分子名称:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
登録日2018-03-19
公開日2018-04-11
最終更新日2019-02-20
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CS2
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SARS SPIKE GLYCOPROTEIN - HUMAN ACE2 COMPLEX, STABILIZED VARIANT, ALL ACE2-BOUND PARTICLES
分子名称:Spike glycoprotein,Fibritin, Angiotensin-converting enzyme 2, N-ACETYL-D-GLUCOSAMINE, ...
著者Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
登録日2018-03-19
公開日2018-04-11
最終更新日2019-02-20
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6NUR
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SARS-CORONAVIRUS NSP12 BOUND TO NSP7 AND NSP8 CO-FACTORS
分子名称:NSP12, NSP8, NSP7, ...
著者Kirchdoerfer, R.N., Ward, A.B.
登録日2019-02-01
公開日2019-05-29
最終更新日2019-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors.
Nat Commun, 10, 2019
6NUS
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SARS-CORONAVIRUS NSP12 BOUND TO NSP8 CO-FACTOR
分子名称:NSP12, NSP8, ZINC ION
著者Kirchdoerfer, R.N., Ward, A.B.
登録日2019-02-01
公開日2019-05-29
最終更新日2019-06-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors.
Nat Commun, 10, 2019
6NUT
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EBOLA VIRUS NUCLEOPROTEIN - RNA COMPLEX
分子名称:Nucleoprotein, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3')
著者Kirchdoerfer, R.N., Ward, A.B.
登録日2019-02-01
公開日2019-05-01
最終更新日2019-11-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structure of the Ebola virus nucleoprotein-RNA complex.
Acta Crystallogr.,Sect.F, 75, 2019
2OP4
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CRYSTAL STRUCTURE OF QUORUM-QUENCHING ANTIBODY 1G9
分子名称:Murine Antibody Fab RS2-1G9 Lambda Light Chain, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, 1,2-ETHANEDIOL
著者Kirchdoerfer, R.N., Debler, E.W., Wilson, I.A.
登録日2007-01-26
公開日2007-05-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
2YMN
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ORGANIZATION OF THE INFLUENZA VIRUS REPLICATION MACHINERY
分子名称:NUCLEOPROTEIN
著者Moeller, A., Kirchdoerfer, R.N., Potter, C.S., Carragher, B., Wilson, I.A.
登録日2012-10-09
公開日2012-12-05
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Organization of the Influenza Virus Replication Machinery.
Science, 338, 2012
5TOH
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CRYSTAL STRUCTURE OF THE MARBURG VIRUS VP35 OLIGOMERIZATION DOMAIN I2
分子名称:Polymerase cofactor VP35
著者Bruhn, J.F., Kirchdoerfer, R.N., Tickle, I.J., Bricogne, G., Saphire, E.O.
登録日2016-10-17
公開日2016-11-09
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal Structure of the Marburg Virus VP35 Oligomerization Domain.
J. Virol., 91, 2017
6BP2
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THERAPEUTIC HUMAN MONOCLONAL ANTIBODY MR191 BOUND TO A MARBURGVIRUS GLYCOPROTEIN
分子名称:Envelope glycoprotein, Envelope glycoprotein GP2, MR191 Fab Heavy Chain, ...
著者King, L.B., Fusco, M.L., Flyak, A.I., Ilinykh, P.A., Huang, K., Gunn, B., Kirchdoerfer, R.N., Hastie, K.M., Sangha, A.K., Meiler, J., Alter, G., Bukreyev, A., Crowe, J.E.J., Saphire, E.O.
登録日2017-11-21
公開日2018-01-17
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (3.172 Å)
主引用文献The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding.
Cell Host Microbe, 23, 2018
3QG7
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STRUCTURAL BASIS FOR LIGAND RECOGNITION AND DISCRIMINATION OF A QUORUM QUENCHING ANTIBODY
分子名称:AP4-24H11 Antibody Heavy Chain, AP4-24H11 Antibody Light Chain, HEXAETHYLENE GLYCOL, ...
著者Kirchdoerfer, R.K., Kaufmann, G.F., Janda, J.D., Wilson, I.A.
登録日2011-01-24
公開日2011-03-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Structural Basis for Ligand Recognition and Discrimination of a Quorum-quenching Antibody.
J.Biol.Chem., 286, 2011
5T3W
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MARBURG VIRUS VP30 BOUND TO NUCLEOPROTEIN
分子名称:Fusion protein of Nucleoprotein and Minor nucleoprotein VP30
著者Kirchdoerfer, R.K., Moyer, C.L., Abelson, D.M., Saphire, E.O.
登録日2016-08-26
公開日2016-09-28
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献The Ebola Virus VP30-NP Interaction Is a Regulator of Viral RNA Synthesis.
Plos Pathog., 12, 2016
2NTF
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CRYSTAL STRUCTURE OF A QUORUM-QUENCHING ANTIBODY IN COMPLEX WITH AN N-ACYL-L-HOMOSERINE LACTONE ANALOG
分子名称:Murine Antibody Fab RS2-1G9 Lambda Light Chain, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, 3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE
著者Debler, E.W., Wilson, I.A.
登録日2006-11-07
公開日2007-05-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
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