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7ZPQ
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BU of 7zpq by Molmil
Structure of the RQT-bound 80S ribosome from S. cerevisiae (C1)
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R.
Deposit date:2022-04-28
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structural basis for clearing of ribosome collisions by the RQT complex.
Nat Commun, 14, 2023
6R86
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BU of 6r86 by Molmil
Yeast Vms1-60S ribosomal subunit complex (post-state)
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R.
Deposit date:2019-03-31
Release date:2019-07-31
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.
Nature, 570, 2019
6R87
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BU of 6r87 by Molmil
Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state without Arb1)
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R.
Deposit date:2019-03-31
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.
Nature, 570, 2019
6R84
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BU of 6r84 by Molmil
Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state with Arb1)
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R.
Deposit date:2019-03-31
Release date:2019-06-26
Last modified:2019-07-10
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.
Nature, 570, 2019
7ZS5
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BU of 7zs5 by Molmil
Structure of 60S ribosomal subunit from S. cerevisiae with eIF6 and tRNA
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R.
Deposit date:2022-05-06
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for clearing of ribosome collisions by the RQT complex.
Nat Commun, 14, 2023
7ZUW
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BU of 7zuw by Molmil
Structure of RQT (C1) bound to the stalled ribosome in a disome unit from S. cerevisiae
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R.
Deposit date:2022-05-13
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis for clearing of ribosome collisions by the RQT complex.
Nat Commun, 14, 2023
7ZUX
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BU of 7zux by Molmil
Collided ribosome in a disome unit from S. cerevisiae
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R.
Deposit date:2022-05-13
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural basis for clearing of ribosome collisions by the RQT complex.
Nat Commun, 14, 2023
7ZRS
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BU of 7zrs by Molmil
Structure of the RQT-bound 80S ribosome from S. cerevisiae (C2) - composite map
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R.
Deposit date:2022-05-05
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural basis for clearing of ribosome collisions by the RQT complex.
Nat Commun, 14, 2023
7ZW0
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BU of 7zw0 by Molmil
FAP-80S Complex - Rotated state
Descriptor: 18S ribosomal RNA (RDN18-1), 25S ribosomal RNA (RDN25-1), 40S ribosomal protein S0-A, ...
Authors:Ikeuchi, K, Buschauer, R, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2022-05-17
Release date:2022-10-05
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover.
Mol.Cell, 82, 2022
7QVP
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BU of 7qvp by Molmil
Human collided disome (di-ribosome) stalled on XBP1 mRNA
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Denk, T.G, Tesina, P, Beckmann, R.
Deposit date:2022-01-22
Release date:2022-10-12
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.
Nat Commun, 13, 2022
6I7O
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BU of 6i7o by Molmil
The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways recognition.
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Tesina, P, Cheng, J, Becker, T, Beckmann, R.
Deposit date:2018-11-16
Release date:2019-01-16
Last modified:2019-03-13
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways.
EMBO J., 38, 2019
6TB3
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BU of 6tb3 by Molmil
yeast 80S ribosome in complex with the Not5 subunit of the CCR4-NOT complex
Descriptor: 25S rRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Buschauer, R, Cheng, J, Berninghausen, O, Tesina, P, Becker, T, Beckmann, R.
Deposit date:2019-10-31
Release date:2020-04-22
Last modified:2020-04-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The Ccr4-Not complex monitors the translating ribosome for codon optimality.
Science, 368, 2020
6TNU
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BU of 6tnu by Molmil
Yeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs.
Descriptor: 18S rRNA, 25S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ...
Authors:Buschauer, R, Cheng, J, Berninghausen, O, Tesina, P, Becker, T, Beckmann, R.
Deposit date:2019-12-10
Release date:2020-04-22
Last modified:2020-04-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The Ccr4-Not complex monitors the translating ribosome for codon optimality.
Science, 368, 2020
7W3N
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BU of 7w3n by Molmil
Crystal structure of Ufm1 fused to UFBP1 UFIM
Descriptor: UFBP1 peptide,Ubiquitin-fold modifier 1
Authors:Noda, N.N.
Deposit date:2021-11-25
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.
Nat Commun, 13, 2022
7W3O
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BU of 7w3o by Molmil
Crystal structure of human CYB5R3
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 3 soluble form
Authors:Noda, N.N.
Deposit date:2021-11-25
Release date:2022-12-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.
Nat Commun, 13, 2022
6SNT
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BU of 6snt by Molmil
Yeast 80S ribosome stalled on SDD1 mRNA.
Descriptor: 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, 40S ribosomal protein S10-A, ...
Authors:Tesina, P, Buschauer, R, Cheng, J, Becker, T, Beckmann, R.
Deposit date:2019-08-27
Release date:2020-03-04
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.
Nat.Struct.Mol.Biol., 27, 2020
6SV4
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BU of 6sv4 by Molmil
The cryo-EM structure of SDD1-stalled collided trisome.
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Tesina, P, Buschauer, R, Cheng, J, Becker, T, Beckmann, R.
Deposit date:2019-09-17
Release date:2020-03-04
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.
Nat.Struct.Mol.Biol., 27, 2020
3WXM
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BU of 3wxm by Molmil
Crystal structure of archaeal Pelota and GTP-bound EF1 alpha complex
Descriptor: Elongation factor 1-alpha, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kobayashi, K, Ishitani, R, Nureki, O.
Deposit date:2014-08-04
Release date:2014-09-03
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for mRNA surveillance by archaeal Pelota and GTP-bound EF1 alpha complex
Proc.Natl.Acad.Sci.USA, 107, 2010
8C83
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BU of 8c83 by Molmil
Cryo-EM structure of in vitro reconstituted Otu2-bound Ub-40S complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-18
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8CAS
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BU of 8cas by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-24
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8CAH
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BU of 8cah by Molmil
Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-24
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8CBJ
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BU of 8cbj by Molmil
Cryo-EM structure of Otu2-bound cytoplasmic pre-40S ribosome biogenesis complex
Descriptor: 20S pre-ribosomal RNA, 20S-pre-rRNA D-site endonuclease NOB1, 40S ribosomal protein S0-A, ...
Authors:Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2023-01-25
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
8AGU
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BU of 8agu by Molmil
Yeast RQC complex in state E
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Tesina, P, Buschauer, R, Beckmann, R.
Deposit date:2022-07-20
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGX
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BU of 8agx by Molmil
Yeast RQC complex in state with the RING domain of Ltn1 in the IN position
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Tesina, P, Buschauer, R, Beckmann, R.
Deposit date:2022-07-20
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGV
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BU of 8agv by Molmil
Yeast RQC complex in state H
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Tesina, P, Buschauer, R, Beckmann, R.
Deposit date:2022-07-20
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023

 

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