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7ZJW
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BU of 7zjw by Molmil
Rabbit 80S ribosome as it decodes the Sec-UGA codon
Descriptor: 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ...
Authors:Hilal, T, Simonovic, M, Spahn, C.M.T.
Deposit date:2022-04-12
Release date:2022-10-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
Science, 376, 2022
5M1J
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BU of 5m1j by Molmil
Nonstop ribosomal complex bound with Dom34 and Hbs1
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Hilal, T, Yamamoto, H, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2016-10-07
Release date:2017-01-18
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution.
Nat Commun, 7, 2016
7ZJX
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BU of 7zjx by Molmil
Rabbit 80S ribosome programmed with SECIS and SBP2
Descriptor: 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ...
Authors:Hilal, T, Simonovic, M, Spahn, C.M.T.
Deposit date:2022-04-12
Release date:2022-09-07
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
Science, 376, 2022
7BL5
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BU of 7bl5 by Molmil
pre-50S-ObgE particle
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
Authors:Hilal, T, Nikolay, R, Spahn, C.M.T, Schmidt, S.
Deposit date:2021-01-18
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
7BL4
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BU of 7bl4 by Molmil
in vitro reconstituted 50S-ObgE-GMPPNP-RsfS particle
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Hilal, T, Nikolay, R, Spahn, C.M.T.
Deposit date:2021-01-18
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
7BL6
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BU of 7bl6 by Molmil
50S-ObgE-GMPPNP particle
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T.
Deposit date:2021-01-18
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
7BL2
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BU of 7bl2 by Molmil
pre-50S-ObgE particle state 1
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ...
Authors:Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T.
Deposit date:2021-01-18
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
7BL3
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BU of 7bl3 by Molmil
pre-50S-ObgE particle state 2
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ...
Authors:Hilal, T, Nikolay, R, Spahn, C.M.T.
Deposit date:2021-01-18
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
6GBZ
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BU of 6gbz by Molmil
50S ribosomal subunit assembly intermediate state 5
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Nikolay, R, Hilal, T, Qin, B, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2018-04-16
Release date:2018-06-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
5FLX
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BU of 5flx by Molmil
Mammalian 40S HCV-IRES complex
Descriptor: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ...
Authors:Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T.
Deposit date:2015-10-28
Release date:2015-12-23
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA.
Embo J., 34, 2015
8ALZ
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BU of 8alz by Molmil
Cryo-EM structure of ASCC3 in complex with ASC1
Descriptor: Activating signal cointegrator 1, Activating signal cointegrator 1 complex subunit 3, ZINC ION
Authors:Jia, J, Hilal, T, Loll, B, Wahl, M.C.
Deposit date:2022-08-01
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of ASCC3 in complex with ASC1
Nat Commun, 2023
6TQN
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BU of 6tqn by Molmil
rrn anti-termination complex without S4
Descriptor: 30S ribosomal protein S10, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N.
Deposit date:2019-12-17
Release date:2020-08-05
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis.
Mol.Cell, 79, 2020
6TQO
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BU of 6tqo by Molmil
rrn anti-termination complex
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S4, DNA-directed RNA polymerase subunit alpha, ...
Authors:Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N.
Deposit date:2019-12-17
Release date:2020-08-05
Last modified:2020-12-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis.
Mol.Cell, 79, 2020
6Z9T
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BU of 6z9t by Molmil
Transcription termination intermediate complex 5
Descriptor: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Said, N, Hilal, T, Loll, B, Wahl, M.C.
Deposit date:2020-06-04
Release date:2020-11-04
Last modified:2021-02-03
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
6Z9P
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BU of 6z9p by Molmil
Transcription termination intermediate complex 1
Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Said, N, Hilal, T, Loll, B, Wahl, M.C.
Deposit date:2020-06-04
Release date:2020-11-04
Last modified:2021-02-03
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
6Z9Q
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BU of 6z9q by Molmil
Transcription termination intermediate complex 2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ...
Authors:Said, N, Hilal, T, Loll, B, Wahl, M.C.
Deposit date:2020-06-04
Release date:2020-11-04
Last modified:2021-02-03
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Steps toward translocation-independent RNA polymerase inactivation by terminator ATPase rho.
Science, 371, 2021
4D61
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BU of 4d61 by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Descriptor: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ...
Authors:Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
Deposit date:2014-11-07
Release date:2015-03-04
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
4D67
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BU of 4d67 by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Descriptor: 28S RRNA, 5.8S RRNA, 5S RRNA, ...
Authors:Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
Deposit date:2014-11-10
Release date:2015-03-04
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State
Mol.Cell, 57, 2015
4D5N
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BU of 4d5n by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Descriptor: CRICKET PARALYSIS VIRUS IRES RNA, EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1
Authors:Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
Deposit date:2014-11-06
Release date:2015-02-04
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
4D5L
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BU of 4d5l by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Descriptor: 18S RRNA 2, 40S RIBOSOMAL PROTEIN ES1, 40S RIBOSOMAL PROTEIN ES10, ...
Authors:Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
Deposit date:2014-11-05
Release date:2015-02-04
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.
Mol.Cell, 57, 2015
4D5Y
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BU of 4d5y by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
Descriptor: 28S Ribosomal RNA, 5.8S Ribosomal RNA, 5S Ribosomal RNA, ...
Authors:Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
Deposit date:2014-11-07
Release date:2015-03-04
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State
Mol.Cell, 57, 2015
7PX3
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BU of 7px3 by Molmil
Structure of U5 snRNP assembly and recycling factor TSSC4 in complex with BRR2 and Jab1 domain of PRPF8
Descriptor: Pre-mRNA-processing-splicing factor 8, Protein TSSC4, U5 small nuclear ribonucleoprotein 200 kDa helicase
Authors:Bergfort, A, Kuropka, B, Ilik, I.A, Freund, C, Aktas, T, Hilal, T, Weber, G, Wahl, M.C.
Deposit date:2021-10-07
Release date:2022-01-26
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
7OS2
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BU of 7os2 by Molmil
Cryo-EM structure of Brr2 in complex with Jab1/MPN and C9ORF78
Descriptor: Pre-mRNA-processing-splicing factor 8, Telomere length and silencing protein 1 homolog, U5 small nuclear ribonucleoprotein 200 kDa helicase
Authors:Bergfort, A, Hilal, T, Weber, G, Wahl, M.C.
Deposit date:2021-06-07
Release date:2022-02-23
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
7OS1
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BU of 7os1 by Molmil
Cryo-EM structure of Brr2 in complex with Fbp21
Descriptor: U5 small nuclear ribonucleoprotein 200 kDa helicase, WW domain-binding protein 4
Authors:Bergfort, A, Hilal, T, Weber, G, Wahl, M.C.
Deposit date:2021-06-07
Release date:2022-02-23
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The intrinsically disordered TSSC4 protein acts as a helicase inhibitor, placeholder and multi-interaction coordinator during snRNP assembly and recycling.
Nucleic Acids Res., 50, 2022
7PIU
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BU of 7piu by Molmil
Cryo-EM structure of the agonist setmelanotide bound to the active melanocortin-4 receptor (MC4R) in complex with the heterotrimeric Gs protein at 2.6 A resolution.
Descriptor: CALCIUM ION, Camelid antibody fragment - nanobody 35, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Heyder, N.A, Schmidt, A, Kleinau, G, Hilal, T, Scheerer, P.
Deposit date:2021-08-23
Release date:2021-11-17
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-alpha-MSH and setmelanotide.
Cell Res., 31, 2021

 

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