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1PX5
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BU of 1px5 by Molmil
Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase
Descriptor: 2'-5'-oligoadenylate synthetase 1, SULFATE ION
Authors:Hartmann, R, Justesen, J, Sarkar, S.N, Sen, G.C, Yee, V.C.
Deposit date:2003-07-02
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase
Mol.Cell, 12, 2003
4AC5
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BU of 4ac5 by Molmil
Lipidic sponge phase crystal structure of the Bl. viridis reaction centre solved using serial femtosecond crystallography
Descriptor: 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ...
Authors:Johansson, L.C, Arnlund, D, White, T.A, Katona, G, DePonte, D.P, Weierstall, U, Doak, R.B, Shoeman, R.L, Lomb, L, Malmerberg, E, Davidsson, J, Nass, K, Liang, M, Andreasson, J, Aquila, A, Bajt, S, Barthelmess, M, Barty, A, Bogan, M.J, Bostedt, C, Bozek, J.D, Caleman, C, Coffee, R, Coppola, N, Ekeberg, T, Epp, S.W, Erk, B, Fleckenstein, H, Foucar, L, Graafsma, H, Gumprecht, L, Hajdu, J, Hampton, C.Y, Hartmann, R, Hartmann, A, Hauser, G, Hirsemann, H, Holl, P, Hunter, M.S, Kassemeyer, S, Kimmel, N, Kirian, R.A, Maia, F.R.N.C, Marchesini, S, Martin, A.V, Reich, C, Rolles, D, Rudek, B, Rudenko, A, Schlichting, I, Schulz, J, Seibert, M.M, Sierra, R, Soltau, H, Starodub, D, Stellato, F, Stern, S, Struder, L, Timneanu, N, Ullrich, J, Wahlgren, W.Y, Wang, X, Weidenspointner, G, Wunderer, C, Fromme, P, Chapman, H.N, Spence, J.C.H, Neutze, R.
Deposit date:2011-12-14
Release date:2012-02-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (8.2 Å)
Cite:Lipidic Phase Membrane Protein Serial Femtosecond Crystallography.
Nat.Methods, 9, 2012
7ZGO
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BU of 7zgo by Molmil
Cryo-EM structure of human NKCC1 (TM domain)
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, ...
Authors:Nissen, P, Fenton, R, Neumann, C, Lindtoft Rosenbaek, L, Kock Flygaard, R, Habeck, M, Lykkegaard Karlsen, J, Wang, Y, Lindorff-Larsen, K, Gad, H, Hartmann, R, Lyons, J.
Deposit date:2022-04-04
Release date:2022-10-05
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity.
Embo J., 41, 2022
4XQ7
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BU of 4xq7 by Molmil
The crystal structure of the OAS-like domain (OLD) of human OASL
Descriptor: 2'-5'-oligoadenylate synthase-like protein
Authors:Ibsen, M.S, Gad, H.H, Andersen, L.L, Hornung, V, Julkunen, I, Sarkar, S.N, Hartmann, R.
Deposit date:2015-01-19
Release date:2015-04-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling.
Nucleic Acids Res., 43, 2015
3PCQ
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BU of 3pcq by Molmil
Femtosecond X-ray protein Nanocrystallography
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
Authors:Chapman, H.N, Fromme, P, Barty, A, White, T.A, Kirian, R.A, Aquila, A, Hunter, M.S, Schulz, J, Deponte, D.P, Weierstall, U, Doak, R.B, Maia, F.R.N.C, Martin, A.V, Schlichting, I, Lomb, L, Coppola, N, Shoeman, R.L, Epp, S.W, Hartmann, R, Rolles, D, Rudenko, A, Foucar, L, Kimmel, N, Weidenspointner, G, Holl, P, Liang, M, Barthelmess, M, Caleman, C, Boutet, S, Bogan, M.J, Krzywinski, J, Bostedt, C, Bajt, S, Gumprecht, L, Rudek, B, Erk, B, Schmidt, C, Homke, A, Reich, C, Pietschner, D, Struder, L, Hauser, G, Gorke, H, Ullrich, J, Herrmann, S, Schaller, G, Schopper, F, Soltau, H, Kuhnel, K.-U, Messerschmidt, M, Bozek, J.D, Hau-Riege, S.P, Frank, M, Hampton, C.Y, Sierra, R, Starodub, D, Williams, G.J, Hajdu, J, Timneanu, N, Seibert, M.M, Andreasson, J, Rocker, A, Jonsson, O, Svenda, M, Stern, S, Nass, K, Andritschke, R, Schroter, C.-D, Krasniqi, F, Bott, M, Schmidt, K.E, Wang, X, Grotjohann, I, Holton, J.M, Barends, T.R.M, Neutze, R, Marchesini, S, Fromme, R, Schorb, S, Rupp, D, Adolph, M, Gorkhover, T, Andersson, I, Hirsemann, H, Potdevin, G, Graafsma, H, Nilsson, B, Spence, J.C.H.
Deposit date:2010-10-21
Release date:2011-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (8.984 Å)
Cite:Femtosecond X-ray protein nanocrystallography.
Nature, 470, 2011
3PIW
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BU of 3piw by Molmil
Zebrafish interferon 2
Descriptor: Type I interferon 2
Authors:Hamming, O.J, Hartmann, R, Lutfalla, G, Levraud, J.-P.
Deposit date:2010-11-08
Release date:2011-07-20
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.492 Å)
Cite:Crystal Structure of Zebrafish Interferons I and II Reveals Conservation of Type I Interferon Structure in Vertebrates.
J.Virol., 85, 2011
3PIV
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BU of 3piv by Molmil
Zebrafish interferon 1
Descriptor: Interferon, NICKEL (II) ION
Authors:Hamming, O.J, Hartmann, R, Lutfalla, G, Levraud, J.-P.
Deposit date:2010-11-08
Release date:2011-07-20
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.086 Å)
Cite:Crystal Structure of Zebrafish Interferons I and II Reveals Conservation of Type I Interferon Structure in Vertebrates.
J.Virol., 85, 2011
3TGX
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BU of 3tgx by Molmil
IL-21:IL21R complex
Descriptor: Interleukin-21, Interleukin-21 receptor, NICKEL (II) ION, ...
Authors:Hamming, O.J, Kang, L, Svenson, A, Karlsen, J.L, Rahbek-Nielsen, H, Paludan, S.R, Hjort, S.A, Bondensgaard, K, Hartmann, R.
Deposit date:2011-08-18
Release date:2012-02-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the interleukin 21 receptor bound to interleukin 21 reveals that a sugar chain interacting with the WSXWS motif is an integral part of the interleukin 21 receptor.
J.Biol.Chem., 2012
4NZD
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BU of 4nzd by Molmil
Interleukin 21 receptor
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Interleukin-21 receptor, ...
Authors:Hamming, O.T, Kang, L, Siupka, P, Gad, H.H, Hartmann, R.
Deposit date:2013-12-12
Release date:2014-12-17
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Interleukin 21 receptor structure and function
To be Published
4O6K
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BU of 4o6k by Molmil
The crystal structure of zebrafish IL-22
Descriptor: Interleukin 22
Authors:Siupka, P, Hamming, O.J, Fretaud, M, Luftalla, G, Levraud, J.P, Hartmann, R.
Deposit date:2013-12-21
Release date:2014-09-10
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of zebrafish IL-22 reveals an evolutionary, conserved structure highly similar to that of human IL-22.
Genes Immun., 15, 2014
2YOM
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BU of 2yom by Molmil
Solution NMR structure of the C-terminal extension of two bacterial light, oxygen, voltage (LOV) photoreceptor proteins from Pseudomonas putida
Descriptor: SENSORY BOX PROTEIN
Authors:Rani, R, Lecher, J, Hartmann, R, Krauss, U, Jaeger, K, Willbold, D.
Deposit date:2012-10-25
Release date:2013-07-10
Last modified:2019-10-23
Method:SOLUTION NMR
Cite:Conservation of Dark Recovery Kinetic Parameters and Structural Features in the Pseudomonadaceae "Short" Light, Oxygen, Voltage (Lov) Protein Family: Implications for the Design of Lov-Based Optogenetic Tools.
Biochemistry, 52, 2013
2YON
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BU of 2yon by Molmil
Solution NMR structure of the C-terminal extension of two bacterial light, oxygen, voltage (LOV) photoreceptor proteins from Pseudomonas putida
Descriptor: SENSORY BOX PROTEIN
Authors:Rani, R, Hartmann, R, Lecher, J, Krauss, U, Jaeger, K, Willbold, D.
Deposit date:2012-10-25
Release date:2013-07-10
Last modified:2019-10-23
Method:SOLUTION NMR
Cite:Conservation of Dark Recovery Kinetic Parameters and Structural Features in the Pseudomonadaceae "Short" Light, Oxygen, Voltage (Lov) Protein Family: Implications for the Design of Lov-Based Optogenetic Tools.
Biochemistry, 52, 2013
3HAK
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BU of 3hak by Molmil
Human prion protein variant V129
Descriptor: Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-01
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HAF
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BU of 3haf by Molmil
Human prion protein variant V129 domain swapped dimer
Descriptor: CADMIUM ION, CHLORIDE ION, Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-01
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HEQ
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BU of 3heq by Molmil
Human prion protein variant D178N with M129
Descriptor: CADMIUM ION, Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-10
Release date:2010-01-12
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HES
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BU of 3hes by Molmil
Human prion protein variant F198S with M129
Descriptor: CADMIUM ION, Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-10
Release date:2010-01-12
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HHC
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BU of 3hhc by Molmil
Interferon-lambda is functionally an interferon but structurally related to the IL-10 family
Descriptor: IODIDE ION, Interleukin-28B
Authors:Gad, H.H, Hamming, O.J, Hartmann, R.
Deposit date:2009-05-15
Release date:2009-07-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Interferon-{lambda} Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family
J.Biol.Chem., 284, 2009
3HER
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BU of 3her by Molmil
Human prion protein variant F198S with V129
Descriptor: CADMIUM ION, Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-10
Release date:2010-01-12
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HJX
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BU of 3hjx by Molmil
Human prion protein variant D178N with V129
Descriptor: CADMIUM ION, CHLORIDE ION, Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-22
Release date:2010-01-12
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3HJ5
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BU of 3hj5 by Molmil
Human prion protein variant V129 domain swapped dimer
Descriptor: Major prion protein
Authors:Lee, S, Antony, L, Hartmann, R, Knaus, K.J, Surewicz, K, Surewicz, W.K, Yee, V.C.
Deposit date:2009-05-20
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Conformational diversity in prion protein variants influences intermolecular beta-sheet formation.
Embo J., 29, 2010
3L9J
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BU of 3l9j by Molmil
Selection of a novel highly specific TNFalpha antagonist: Insight from the crystal structure of the antagonist-TNFalpha complex
Descriptor: MAGNESIUM ION, TNFalpha, Tumor necrosis factor, ...
Authors:Byla, P, Andersen, M.H, Thogersen, H.C, Gad, H.H, Hartmann, R.
Deposit date:2010-01-05
Release date:2010-02-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Selection of a novel and highly specific TNF{alpha} antagonist: insight from the crystal structure of the antagonist-TNF{alpha} complex
J.Biol.Chem., 285, 2010
3MOR
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BU of 3mor by Molmil
Crystal structure of Cathepsin B from Trypanosoma Brucei
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Cathepsin B-like cysteine protease, ...
Authors:Cupelli, K, Stehle, T.
Deposit date:2010-04-23
Release date:2011-11-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:In vivo protein crystallization opens new routes in structural biology.
Nat.Methods, 9, 2012
5J3W
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BU of 5j3w by Molmil
Crystal structures reveal signaling states of a short blue light photoreceptor protein PpSB1-LOV (dark state)
Descriptor: FLAVIN MONONUCLEOTIDE, Sensory box protein
Authors:Granzin, J, Batra-Safferling, R.
Deposit date:2016-03-31
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Signaling States of a Short Blue-Light Photoreceptor Protein PpSB1-LOV Revealed from Crystal Structures and Solution NMR Spectroscopy.
J.Mol.Biol., 428, 2016
5J4E
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BU of 5j4e by Molmil
Crystal structures reveal signaling states of a short blue light photoreceptor protein PpSB1-LOV (Photoexcited state)
Descriptor: FLAVIN MONONUCLEOTIDE, Sensory box protein
Authors:Granzin, J, Batra-Safferling, R.
Deposit date:2016-04-01
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Signaling States of a Short Blue-Light Photoreceptor Protein PpSB1-LOV Revealed from Crystal Structures and Solution NMR Spectroscopy.
J.Mol.Biol., 428, 2016
7UCW
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BU of 7ucw by Molmil
Structure of mouse Decr1 in complex with 2'-5' oligoadenylate
Descriptor: Decr1 protein, [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
Authors:Govande, A.A, Kranzusch, P.J.
Deposit date:2022-03-17
Release date:2023-03-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:RNase L-activating 2'-5' oligoadenylates bind ABCF1, ABCF3 and Decr-1.
J.Gen.Virol., 104, 2023

 

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