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4V19
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BU of 4v19 by Molmil
Structure of the large subunit of the mammalian mitoribosome, part 1 of 2
Descriptor: MAGNESIUM ION, MITORIBOSOMAL 16S RRNA, MITORIBOSOMAL CP TRNA, ...
Authors:Greber, B.J, Boehringer, D, Leibundgut, M, Bieri, P, Leitner, A, Schmitz, N, Aebersold, R, Ban, N.
Deposit date:2014-09-25
Release date:2014-10-08
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The Complete Structure of the Large Subunit of the Mammalian Mitochondrial Ribosome
Nature, 515, 2014
4V8T
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BU of 4v8t by Molmil
Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1
Descriptor: 25S RIBOSOMAL RNA, 5.8S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, ...
Authors:Greber, B.J, Boehringer, D, Montellese, C, Ban, N.
Deposit date:2012-08-07
Release date:2014-07-09
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Cryo-Em Structures of Arx1 and Maturation Factors Rei1 and Jjj1 Bound to the 60S Ribosomal Subunit
Nat.Struct.Mol.Biol., 19, 2012
4V1A
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BU of 4v1a by Molmil
Structure of the large subunit of the mammalian mitoribosome, part 2 of 2
Descriptor: MITORIBOSOMAL PROTEIN ML37, MRPL37, MITORIBOSOMAL PROTEIN ML38, ...
Authors:Greber, B.J, Boehringer, D, Leibundgut, M, Bieri, P, Leitner, A, Schmitz, N, Aebersold, R, Ban, N.
Deposit date:2014-09-25
Release date:2014-10-08
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The Complete Structure of the Large Subunit of the Mammalian Mitochondrial Ribosome
Nature, 515, 2014
5OF4
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BU of 5of4 by Molmil
The cryo-EM structure of human TFIIH
Descriptor: General transcription factor IIH subunit 2, General transcription factor IIH subunit 3, General transcription factor IIH subunit 4,p52,General transcription factor IIH subunit 4, ...
Authors:Greber, B.J, Nguyen, T.H.D, Fang, J, Afonine, P.V, Adams, P.D, Nogales, E.
Deposit date:2017-07-10
Release date:2017-09-13
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The cryo-electron microscopy structure of human transcription factor IIH.
Nature, 549, 2017
7B5O
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BU of 7b5o by Molmil
Cryo-EM structure of the human CAK bound to ICEC0942 at 2.5 Angstroms resolution
Descriptor: (3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, CDK-activating kinase assembly factor MAT1, Cyclin-H, ...
Authors:Greber, B.J, Remis, J, Ali, S, Nogales, E.
Deposit date:2020-12-05
Release date:2021-02-10
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:2.5 angstrom -resolution structure of human CDK-activating kinase bound to the clinical inhibitor ICEC0942.
Biophys.J., 120, 2021
7B5Q
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BU of 7b5q by Molmil
Cryo-EM structure of the human CAK bound to ICEC0942 (PHENIX-OPLS3e)
Descriptor: (3R,4R)-4-[[[7-[(phenylmethyl)amino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, CDK-activating kinase assembly factor MAT1, Cyclin-H, ...
Authors:Greber, B.J, Remis, J, Ali, S, Nogales, E.
Deposit date:2020-12-05
Release date:2021-02-10
Last modified:2021-03-03
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:2.5 angstrom -resolution structure of human CDK-activating kinase bound to the clinical inhibitor ICEC0942.
Biophys.J., 120, 2021
5AJ3
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BU of 5aj3 by Molmil
Structure of the small subunit of the mammalian mitoribosome
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MITORIBOSOMAL 12S RRNA, ...
Authors:Greber, B.J, Bieri, P, Leibundgut, M, Leitner, A, Aebersold, R, Boehringer, D, Ban, N.
Deposit date:2015-02-20
Release date:2015-04-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Ribosome. The complete structure of the 55S mammalian mitochondrial ribosome.
Science, 348, 2015
5AJ4
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BU of 5aj4 by Molmil
Structure of the 55S mammalian mitoribosome.
Descriptor: 28S RIBOSOMAL PROTEIN S18B, MITOCHONDRIAL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Greber, B.J, Bieri, P, Leibundgut, M, Leitner, A, Aebersold, R, Boehringer, D, Ban, N.
Deposit date:2015-02-20
Release date:2015-04-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The complete structure of the 55S mammalian mitochondrial ribosome.
Science, 348, 2015
5APO
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BU of 5apo by Molmil
Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally tagged Rei1
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, N.
Deposit date:2015-09-17
Release date:2015-12-16
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell(Cambridge,Mass.), 164, 2016
5APN
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BU of 5apn by Molmil
Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and N-terminally tagged Rei1
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, V.
Deposit date:2015-09-17
Release date:2015-12-16
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell, 164, 2015
4ADX
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BU of 4adx by Molmil
The Cryo-EM Structure of the Archaeal 50S Ribosomal Subunit in Complex with Initiation Factor 6
Descriptor: 23S Ribosomal RNA EXPANSION SEGMENTS, 23S ribosomal RNA, 5S Ribosomal RNA, ...
Authors:Greber, B.J, Boehringer, D, Godinic-Mikulcic, V, Crnkovic, A, Ibba, M, Weygand-Durasevic, I, Ban, N.
Deposit date:2012-01-04
Release date:2012-02-08
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Cryo-Em Structure of the Archaeal 50S Ribosomal Subunit in Complex with Initiation Factor 6 and Implications for Ribosome Evolution
J.Mol.Biol., 418, 2012
4CE4
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BU of 4ce4 by Molmil
39S large subunit of the porcine mitochondrial ribosome
Descriptor: 16S Ribosomal RNA, ICT1, MRPL13, ...
Authors:Greber, B.J, Boehringer, D, Leitner, A, Bieri, P, Voigts-Hoffmann, F, Erzberger, J.P, Leibundgut, M, Aebersold, R, Ban, N.
Deposit date:2013-11-08
Release date:2013-12-18
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Architecture of the Large Subunit of the Mammalian Mitochondrial Ribosome.
Nature, 505, 2014
6XD3
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BU of 6xd3 by Molmil
Structure of the human CAK in complex with THZ1
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Greber, B.J, Perez-Bertoldi, J.M, Lim, K, Iavarone, A.T, Toso, D.B, Nogales, E.
Deposit date:2020-06-09
Release date:2020-09-09
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The cryoelectron microscopy structure of the human CDK-activating kinase.
Proc.Natl.Acad.Sci.USA, 117, 2020
6XBZ
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BU of 6xbz by Molmil
Structure of the human CDK-activating kinase
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Greber, B.J, Perez-Bertoldi, J.M, Lim, K, Iavarone, A.T, Toso, D.B, Nogales, E.
Deposit date:2020-06-07
Release date:2020-09-09
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:The cryoelectron microscopy structure of the human CDK-activating kinase.
Proc.Natl.Acad.Sci.USA, 117, 2020
6MZV
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BU of 6mzv by Molmil
Cryo-EM structure of the HO BMC shell: BMC-TD focused structure, widened inner ring
Descriptor: Microcompartments protein
Authors:Greber, B.J, Sutter, M, Kerfeld, C.A.
Deposit date:2018-11-05
Release date:2019-03-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly.
Structure, 27, 2019
6MZX
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BU of 6mzx by Molmil
Cryo-EM structure of the HO BMC shell: Icosahedral reconstruction (main population)
Descriptor: Ethanolamine utilization protein EutN/carboxysome structural protein Ccml, Microcompartments protein HO-5815, Microcompartments protein HO-5816
Authors:Greber, B.J, Sutter, M, Kerfeld, C.A.
Deposit date:2018-11-06
Release date:2019-03-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly.
Structure, 27, 2019
6N07
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BU of 6n07 by Molmil
Structure of the HO BMC shell: BMC-TD focused map, open inner pore, compacted shell
Descriptor: Microcompartments protein
Authors:Greber, B.J, Sutter, M, Kerfeld, C.A.
Deposit date:2018-11-06
Release date:2019-03-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly.
Structure, 27, 2019
6N06
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BU of 6n06 by Molmil
Cryo-EM structure of the HO BMC shell: BMC-T1 in the assembled shell
Descriptor: Microcompartments protein
Authors:Greber, B.J, Sutter, M, Kerfeld, C.A.
Deposit date:2018-11-06
Release date:2019-03-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly.
Structure, 27, 2019
6N0F
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BU of 6n0f by Molmil
Cryo-EM structure of the HO BMC shell: subregion classified for BMC-T: TD-TSTSTS
Descriptor: Microcompartments protein
Authors:Greber, B.J, Sutter, M, Kerfeld, C.A.
Deposit date:2018-11-07
Release date:2019-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly.
Structure, 27, 2019
6N0G
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BU of 6n0g by Molmil
Cryo-EM structure of the HO BMC shell: subregion classified for BMC-T: TS-TDTDTD
Descriptor: Microcompartments protein
Authors:Greber, B.J, Sutter, M, Kerfeld, C.A.
Deposit date:2018-11-07
Release date:2019-03-13
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly.
Structure, 27, 2019
6MZY
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BU of 6mzy by Molmil
Cryo-EM structure of the HO BMC shell: Icosahedral reconstruction of the compacted subpopulation
Descriptor: Ethanolamine utilization protein EutN/carboxysome structural protein Ccml, Microcompartments protein
Authors:Greber, B.J, Sutter, M, Kerfeld, C.A.
Deposit date:2018-11-06
Release date:2019-03-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly.
Structure, 27, 2019
6MZU
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BU of 6mzu by Molmil
Cryo-EM structure of the HO BMC shell: BMC-TD focused structure, closed state
Descriptor: Microcompartments protein
Authors:Greber, B.J, Sutter, M, Kerfeld, C.A.
Deposit date:2018-11-05
Release date:2019-03-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly.
Structure, 27, 2019
6N09
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BU of 6n09 by Molmil
Cryo-EM structure of the HO BMC shell: subregion classified for BMC-T: TD-TDTDTD
Descriptor: Microcompartments protein
Authors:Greber, B.J, Sutter, M, Kerfeld, C.A.
Deposit date:2018-11-06
Release date:2019-03-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly.
Structure, 27, 2019
6NMI
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BU of 6nmi by Molmil
Cryo-EM structure of the human TFIIH core complex
Descriptor: CDK-activating kinase assembly factor MAT1, General transcription and DNA repair factor IIH helicase subunit XPB, General transcription and DNA repair factor IIH helicase subunit XPD, ...
Authors:Greber, B.J, Toso, D, Fang, J, Nogales, E.
Deposit date:2019-01-10
Release date:2019-03-13
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The complete structure of the human TFIIH core complex.
Elife, 8, 2019
8PLZ
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BU of 8plz by Molmil
Cryo-EM structure of CAK in complex with inhibitor CT7030
Descriptor: (3~{R},4~{R})-4-[[[7-[(2-methoxyphenyl)methylamino]-3-propan-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol, CDK-activating kinase assembly factor MAT1, Cyclin-H, ...
Authors:Cushing, V.I, Koh, A.F, Feng, J, Jurgaityte, K, Bahl, A.K, Ali, S, Kotecha, A, Greber, B.J.
Deposit date:2023-06-27
Release date:2024-03-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (1.9 Å)
Cite:High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design.
Nat Commun, 15, 2024

 

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