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6QG1
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BU of 6qg1 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 2)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG2
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BU of 6qg2 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model A)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG6
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BU of 6qg6 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model D)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.65 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG0
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BU of 6qg0 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 1)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG3
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BU of 6qg3 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model B)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG5
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BU of 6qg5 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model C)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6ZMW
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BU of 6zmw by Molmil
Structure of a human 48S translational initiation complex
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
Deposit date:2020-07-04
Release date:2020-09-23
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
8OZ0
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BU of 8oz0 by Molmil
Structure of a human 48S translation initiation complex with eIF4F and eIF4A
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Fraser, C.S, Ramakrishnan, V.
Deposit date:2023-05-06
Release date:2024-02-07
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The structure of a human translation initiation complex reveals two independent roles for the helicase eIF4A.
Nat.Struct.Mol.Biol., 31, 2024
5IQR
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BU of 5iqr by Molmil
Structure of RelA bound to the 70S ribosome
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Brown, A, Fernandez, I.S, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2016-03-11
Release date:2016-05-04
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Ribosome-dependent activation of stringent control.
Nature, 534, 2016
3D36
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BU of 3d36 by Molmil
How to Switch Off a Histidine Kinase: Crystal Structure of Geobacillus stearothermophilus KinB with the Inhibitor Sda
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Bick, M.J, Lamour, V, Rajashankar, K.R, Gordiyenko, Y, Robinson, C.V, Darst, S.A.
Deposit date:2008-05-09
Release date:2009-01-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:How to switch off a histidine kinase: crystal structure of Geobacillus stearothermophilus KinB with the inhibitor Sda
J.Mol.Biol., 386, 2009
6FYX
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BU of 6fyx by Molmil
Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
5MDW
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BU of 5mdw by Molmil
Structure of ArfA(A18T) and RF2 bound to the 70S ribosome (pre-accommodated state)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2016-11-13
Release date:2016-12-14
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Translational termination without a stop codon.
Science, 354, 2016
5MDV
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BU of 5mdv by Molmil
Structure of ArfA and RF2 bound to the 70S ribosome (accommodated state)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2016-11-13
Release date:2016-12-14
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Translational termination without a stop codon.
Science, 354, 2016
5MDY
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BU of 5mdy by Molmil
Structure of ArfA and TtRF2 bound to the 70S ribosome (pre-accommodated state)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2016-11-13
Release date:2016-12-21
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Translational termination without a stop codon.
Science, 354, 2016
5MDZ
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BU of 5mdz by Molmil
Structure of the 70S ribosome (empty A site)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2016-11-13
Release date:2016-12-14
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Translational termination without a stop codon.
Science, 354, 2016
6YBT
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BU of 6ybt by Molmil
Structure of a human 48S translational initiation complex - eIF3bgi
Descriptor: Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit B, Eukaryotic translation initiation factor 3 subunit I
Authors:Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
Deposit date:2020-03-17
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
6YBV
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BU of 6ybv by Molmil
Structure of a human 48S translational initiation complex - eIF2-TC
Descriptor: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ...
Authors:Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
Deposit date:2020-03-17
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
6YBS
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BU of 6ybs by Molmil
Structure of a human 48S translational initiation complex - head
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ...
Authors:Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
Deposit date:2020-03-17
Release date:2020-09-16
Last modified:2022-12-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
6YBW
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BU of 6ybw by Molmil
Structure of a human 48S translational initiation complex - 40S body
Descriptor: 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S13, ...
Authors:Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
Deposit date:2020-03-18
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
6YBD
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BU of 6ybd by Molmil
Structure of a human 48S translational initiation complex - eIF3
Descriptor: 40S ribosomal protein S13, 40S ribosomal protein S14, 40S ribosomal protein S17, ...
Authors:Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
Deposit date:2020-03-16
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
6FYY
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BU of 6fyy by Molmil
Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
6GSM
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BU of 6gsm by Molmil
Structure of a partial yeast 48S preinitiation complex in open conformation.
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-07-31
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
4BKX
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BU of 4bkx by Molmil
The structure of HDAC1 in complex with the dimeric ELM2-SANT domain of MTA1 from the NuRD complex
Descriptor: ACETATE ION, HISTONE DEACETYLASE 1, METASTASIS-ASSOCIATED PROTEIN MTA1, ...
Authors:Millard, C.J, Watson, P.J, Celardo, I, Gordiyenko, Y, Cowley, S.M, Robinson, C.V, Fairall, L, Schwabe, J.W.R.
Deposit date:2013-04-30
Release date:2013-07-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Class I Hdacs Share a Common Mechanism of Regulation by Inositol Phosphates.
Mol.Cell, 51, 2013
4CYJ
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BU of 4cyj by Molmil
Chaetomium thermophilum Pan2:Pan3 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, ...
Authors:Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
Deposit date:2014-04-11
Release date:2014-06-11
Last modified:2014-07-30
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
Embo J., 33, 2014
4CYI
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BU of 4cyi by Molmil
Chaetomium thermophilum Pan3
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, ...
Authors:Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
Deposit date:2014-04-11
Release date:2014-06-11
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
Embo J., 33, 2014

 

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