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2BJI
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HIGH RESOLUTION STRUCTURE OF MYO-INOSITOL MONOPHOSPHATASE, THE TARGET OF LITHIUM THERAPY
分子名称:INOSITOL-1(OR 4)-MONOPHOSPHATASE, MAGNESIUM ION
著者Gill, R., Mohammed, F., Badyal, R., Coates, L., Erskine, P., Thompson, D., Cooper, J., Gore, M., Wood, S.
登録日2005-02-03
公開日2005-02-11
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献High-resolution structure of myo-inositol monophosphatase, the putative target of lithium therapy.
Acta Crystallogr. D Biol. Crystallogr., 61, 2005
3EQ1
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THE CRYSTAL STRUCTURE OF HUMAN PORPHOBILINOGEN DEAMINASE AT 2.8A RESOLUTION
分子名称:Porphobilinogen deaminase, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, SULFATE ION
著者Kolstoe, S.E., Gill, R., Mohammed, F., Wood, S.P.
登録日2008-09-30
公開日2009-03-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of human porphobilinogen deaminase at 2.8 A: the molecular basis of acute intermittent porphyria
Biochem.J., 420, 2009
1W31
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YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE 5-HYDROXYLAEVULINIC ACID COMPLEX
分子名称:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, 5-HYDROXYLAEVULINIC ACID, ZINC ION
著者Erskine, P.T., Coates, L., Newbold, R., Brindley, A.A., Stauffer, F., Beaven, G.D.E., Gill, R., Wood, S.P., Warren, M.J., Cooper, J.B., Shoolingin-Jordan, P.M., Neier, R.
登録日2004-07-11
公開日2005-08-23
最終更新日2014-08-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with the Inhibitor 5-Hydroxylaevulinic Acid
Acta Crystallogr.,Sect.D, 61, 2005
1B9G
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INSULIN-LIKE-GROWTH-FACTOR-1
分子名称:PROTEIN (GROWTH FACTOR IGF-1)
著者De Wolf, E., Gill, R., Geddes, S., Pitts, J., Wollmer, A., Grotzinger, J.
登録日1999-02-11
公開日1999-02-23
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of a mini IGF-1.
Protein Sci., 5, 1996
1H4J
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METHYLOBACTERIUM EXTORQUENS METHANOL DEHYDROGENASE D303E MUTANT
分子名称:Methanol dehydrogenase [cytochrome c] subunit 1, Methanol dehydrogenase [cytochrome c] subunit 2, PYRROLOQUINOLINE QUINONE, ...
著者Mohammed, F., Gill, R., Thompson, D., Cooper, J.B., Wood, S.P., Afolabi, P.R., Anthony, C.
登録日2001-05-11
公開日2001-08-23
最終更新日2018-09-19
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Site-Directed Mutagenesis and X-Ray Crystallography of the Pqq-Containing Quinoprotein Methanol Dehydrogenase and its Electron Acceptor, Cytochrome C(L)(,)
Biochemistry, 40, 2001
1QN2
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CYTOCHROME CH FROM METHYLOBACTERIUM EXTORQUENS
分子名称:CYTOCHROME CH, HEME C
著者Read, J., Gill, R., Dales, S.L., Cooper, J.B., Wood, S.P., Anthony, C.
登録日1999-10-13
公開日2000-10-13
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献The Molecular Structure of an Unusual Cytochrome C2 Determined at 2.0A; the Cytochrome cH from Methylobacterium Extorquens
Protein Sci., 8, 1999
1W1Z
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STRUCTURE OF THE PLANT LIKE 5-AMINOLAEVULINIC ACID DEHYDRATASE FROM CHLOROBIUM VIBRIOFORME
分子名称:DELTA-AMINOLEVULINIC ACID DEHYDRATASE, LAEVULINIC ACID, MAGNESIUM ION
著者Coates, L., Beaven, G., Erskine, P.T., Beale, S.I., Avissar, Y.J., Gill, R., Mohammed, F., Wood, S.P., Shoolingin-Jordan, P., Cooper, J.B.
登録日2004-06-24
公開日2004-09-02
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The X-ray structure of the plant like 5-aminolaevulinic acid dehydratase from Chlorobium vibrioforme complexed with the inhibitor laevulinic acid at 2.6 A resolution.
J. Mol. Biol., 342, 2004
1W6S
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THE HIGH RESOLUTION STRUCTURE OF METHANOL DEHYDROGENASE FROM METHYLOBACTERIUM EXTORQUENS
分子名称:METHANOL DEHYDROGENASE SUBUNIT 1, METHANOL DEHYDROGENASE SUBUNIT 2, PYRROLOQUINOLINE QUINONE, ...
著者Williams, P.A., Coates, L., Mohammed, F., Gill, R., Erskine, P.T., Wood, S.P., Anthony, C., Cooper, J.B.
登録日2004-08-23
公開日2004-12-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The Atomic Resolution Structure of Methanol Dehydrogenase from Methylobacterium Extorquens
Acta Crystallogr.,Sect.D, 61, 2005
2C8S
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CYTOCHROME CL FROM METHYLOBACTERIUM EXTORQUENS
分子名称:CYTOCHROME C-L, PROTOPORPHYRIN IX CONTAINING FE, CALCIUM ION
著者Williams, P.A., Coates, L., Mohammed, F., Gill, R., Erskine, P.T., Wood J, S.P., Cooper, B., Anthony, C.
登録日2005-12-06
公開日2005-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The 1.6A X-Ray Structure of the Unusual C-Type Cytochrome, Cytochrome Cl, from the Methylotrophic Bacterium Methylobacterium Extorquens.
J.Mol.Biol., 357, 2006
2IZP
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BIPD - AN INVASION PRTEIN ASSOCIATED WITH THE TYPE-III SECRETION SYSTEM OF BURKHOLDERIA PSEUDOMALLEI.
分子名称:PUTATIVE MEMBRANE ANTIGEN
著者Erskine, P.T., Knight, M.J., Ruaux, A., Mikolajek, H., Wong-Fat-Sang, N., Withers, J., Gill, R., Wood, S.P., Wood, M., Fox, G.C., Cooper, J.B.
登録日2006-07-25
公開日2006-09-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献High Resolution Structure of Bipd: An Invasion Protein Associated with the Type III Secretion System of Burkholderia Pseudomallei.
J.Mol.Biol., 363, 2006
4HTG
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PORPHOBILINOGEN DEAMINASE FROM ARABIDOPSIS THALIANA
分子名称:Porphobilinogen deaminase, chloroplastic, 3-[(5Z)-5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methylidene}-4-(carboxymethyl)-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]propanoic acid, ...
著者Roberts, A., Gill, R., Hussey, R.J., Erskine, P.T., Cooper, J.B., Wood, S.P., Chrystal, E.J.T., Shoolingin-Jordan, P.M.
登録日2012-11-01
公開日2013-02-27
最終更新日2013-04-03
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Insights into the mechanism of pyrrole polymerization catalysed by porphobilinogen deaminase: high-resolution X-ray studies of the Arabidopsis thaliana enzyme.
Acta Crystallogr.,Sect.D, 69, 2013
4YP2
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CLEAVAGE OF NICOTINAMIDE ADENINE DINUCLEOTIDES BY THE RIBOSOME INACTIVATING PROTEIN FROM MOMORDICA CHARANTIA
分子名称:Ribosome-inactivating protein momordin I, N-ACETYL-D-GLUCOSAMINE, NICOTINAMIDE
著者Vinkovic, M., Hussain, J., Wood, G.E., Gill, R., Wood, S.P.
登録日2015-03-12
公開日2015-05-20
最終更新日2015-09-09
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Cleavage of nicotinamide adenine dinucleotide by the ribosome-inactivating protein from Momordica charantia.
Acta Crystallogr.,Sect.F, 71, 2015
5CF9
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CLEAVAGE OF NICOTINAMIDE ADENINE DINUCLEOTIDE BY THE RIBOSOME INACTIVATING PROTEIN OF MOMORDICA CHARANTIA - ENZYME-NADP+ CO-CRYSTALLISATION.
分子名称:Ribosome-inactivating protein momordin I, N-ACETYL-D-GLUCOSAMINE, NICOTINAMIDE
著者Vinkovic, M., Wood, S.P., Gill, R., Husain, J., Wood, G.E., Dunn, G.
登録日2015-07-08
公開日2015-07-22
最終更新日2015-09-09
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Cleavage of nicotinamide adenine dinucleotide by the ribosome-inactivating protein from Momordica charantia.
Acta Crystallogr.,Sect.F, 71, 2015
3IPB
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HUMAN TRANSTHYRETIN (TTR) COMPLEXED WITH A PALINDROMIC BIVALENT AMYLOID INHIBITOR (11 CARBON LINKER).
分子名称:Transthyretin, 2,2'-{undecane-1,11-diylbis[oxy(3,5-dichlorobenzene-4,1-diyl)imino]}dibenzoic acid
著者Kolstoe, S.E., Wood, S.P., Pepys, M.B.
登録日2009-08-17
公開日2010-11-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Proc.Natl.Acad.Sci.USA, 107, 2010
3IPE
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HUMAN TRANSTHYRETIN (TTR) COMPLEXED WITH A PALINDROMIC BIVALENT AMYLOID INHIBITOR (7 CARBON LINKER).
分子名称:Transthyretin, 2,2'-{heptane-1,7-diylbis[oxy(3,5-dichlorobenzene-4,1-diyl)imino]}dibenzoic acid
著者Kolstoe, S.E., Wood, S.P., Pepys, M.B.
登録日2009-08-17
公開日2010-11-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M1O
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HUMAN TRANSTHYRETIN (TTR) COMPLEXED WITH 2-((3,5-DICHLORO-4-HYDROXYPHENYL)AMINO)BENZOIC ACID
分子名称:Transthyretin, 2-[(3,5-dichloro-4-hydroxyphenyl)amino]benzoic acid
著者Kolstoe, S.E., Wood, S.P.
登録日2010-03-05
公開日2010-11-17
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Proc.Natl.Acad.Sci.USA, 107, 2010
5HMS
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X-RAY STRUCTURE OF HUMAN RECOMBINANT 5-AMINOLAEVULINIC ACID DEHYDRATASE (HRALAD).
分子名称:Delta-aminolevulinic acid dehydratase, ZINC ION
著者Butler, D., Erskine, P.T., Cooper, J.B., Shoolingin-Jordan, P.M.
登録日2016-01-17
公開日2016-01-27
最終更新日2017-03-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5HNR
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THE X-RAY STRUCTURE OF OCTAMERIC HUMAN NATIVE 5-AMINOLAEVULINIC ACID DEHYDRATASE.
分子名称:Delta-aminolevulinic acid dehydratase, ZINC ION, SULFATE ION, ...
著者Mills-Davies, N.L., Thompson, D., Shoolingin-Jordan, P.M., Erskine, P.T., Cooper, J.B.
登録日2016-01-18
公開日2016-01-27
最終更新日2017-01-25
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5LZL
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PYROBACULUM CALIDIFONTIS 5-AMINOLAEVULINIC ACID DEHYDRATASE
分子名称:Delta-aminolevulinic acid dehydratase, ZINC ION
著者Azim, N., Erskine, P.T., Guo, J., Cooper, J.B.
登録日2016-09-30
公開日2016-10-12
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (3.47 Å)
主引用文献Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
5MHB
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PRODUCT-COMPLEX OF E.COLI 5-AMINO LAEVULINIC ACID DEHYDRATASE
分子名称:Delta-aminolevulinic acid dehydratase, 3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC ACID, ZINC ION, ...
著者Norton, E., Erskine, P.T., Shoolingin-Jordan, P.M., Cooper, J.B.
登録日2016-11-23
公開日2016-12-07
最終更新日2017-01-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.
Acta Crystallogr D Struct Biol, 73, 2017
6GIU
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HUMAN IMPASE WITH L-690330
分子名称:Inositol monophosphatase 1, MANGANESE (II) ION, [1-(4-oxidanylphenoxy)-1-phosphono-ethyl]phosphonic acid, ...
著者Kraft, L.V., Roe, S.M.
登録日2018-05-15
公開日2018-10-17
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Co-crystallization of human inositol monophosphatase with the lithium mimetic L-690,330.
Acta Crystallogr D Struct Biol, 74, 2018
6GJ0
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HUMAN IMPASE WITH MN
分子名称:Inositol monophosphatase 1, MANGANESE (II) ION, GLYCEROL, ...
著者Kraft, L.V., Roe, S.M.
登録日2018-05-15
公開日2018-10-17
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Co-crystallization of human inositol monophosphatase with the lithium mimetic L-690,330.
Acta Crystallogr D Struct Biol, 74, 2018