4INS | | THE STRUCTURE OF 2ZN PIG INSULIN CRYSTALS AT 1.5 ANGSTROMS RESOLUTION | | 分子名称: | INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION | | 著者 | Dodson, G.G., Dodson, E.J., Hodgkin, D.C., Isaacs, N.W., Vijayan, M. | | 登録日 | 1989-07-10 | | 公開日 | 1990-04-15 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The structure of 2Zn pig insulin crystals at 1.5 A resolution.
Philos.Trans.R.Soc.London,Ser.B, 319, 1988
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2INS | | THE STRUCTURE OF DES-PHE B1 BOVINE INSULIN | | 分子名称: | DES-PHE B1 INSULIN (CHAIN A), DES-PHE B1 INSULIN (CHAIN B), ZINC ION | | 著者 | Smith, G.D., Duax, W.L., Dodson, E.J., Dodson, G.G., Degraaf, R.A.G., Reynolds, C.D. | | 登録日 | 1982-05-10 | | 公開日 | 1982-08-05 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The Structure of Des-Phe B1 Bovine Insulin
Acta Crystallogr.,Sect.B, 38, 1982
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1ZNI | | INSULIN | | 分子名称: | INSULIN, ZINC ION, CHLORIDE ION | | 著者 | Turkenburg, M.G.W., Whittingham, J.L., Dodson, G.G., Dodson, E.J., Xiao, B., Bentley, G.A. | | 登録日 | 1997-09-23 | | 公開日 | 1998-01-28 | | 最終更新日 | 2018-07-04 | | 実験手法 | X-RAY DIFFRACTION (1.498 Å) | | 主引用文献 | Structure of insulin in 4-zinc insulin.
Nature, 261, 1976
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3JSD | | INSULIN'S BIOSYNTHESIS AND ACTIVITY HAVE OPPOSING STRUCTURAL REQUIREMENTS: A NEW FACTOR IN NEONATAL DIABETES MELLITUS | | 分子名称: | Insulin A chain, Insulin B chain, ZINC ION, ... | | 著者 | Weiss, M.A., Wan, Z.L., Dodson, E.J., Liu, M., Xu, B., Hua, Q.X., Turkenburg, M., Whittingham, J., Nakagawa, S.H., Huang, K., Hu, S.Q., Jia, W.H., Wang, S.H., Brange, J., Whittaker, J., Arvan, P., Katsoyannis, P.G., Dodson, G.G. | | 登録日 | 2009-09-10 | | 公開日 | 2010-09-15 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
To be Published
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1ZNJ | | INSULIN, MONOCLINIC CRYSTAL FORM | | 分子名称: | INSULIN, PHENOL, ZINC ION, ... | | 著者 | Turkenburg, M.G.W., Whittingham, J.L., Turkenburg, J.P., Dodson, G.G., Derewenda, U., Smith, G.D., Dodson, E.J., Derewenda, Z.S., Xiao, B. | | 登録日 | 1997-09-23 | | 公開日 | 1998-01-28 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure Determination and Refinement of Two Crystal Forms of Native Insulins
To be Published
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3TGL | | STRUCTURE AND MOLECULAR MODEL REFINEMENT OF RHIZOMUCOR MIEHEI TRIACYLGLYCERIDE LIPASE: A CASE STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT | | 分子名称: | TRIACYL-GLYCEROL ACYLHYDROLASE | | 著者 | Brady, L., Brzozowski, A.M., Derewenda, Z.S., Dodson, E.J., Dodson, G.G., Tolley, S.P., Turkenburg, J.P., Christiansen, L., Huge-Jensen, B., Norskov, L., Thim, L. | | 登録日 | 1991-07-29 | | 公開日 | 1993-07-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | STRUCTURE AND MOLECULAR-MODEL REFINEMENT OF RHIZOMUCOR-MIEHEI TRIACYLGLYCERIDE LIPASE - A CASE-STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT.
Acta Crystallogr.,Sect.B, 48, 1992
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1MPJ | | X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL | | 分子名称: | PHENOL INSULIN, PHENOL, ZINC ION, ... | | 著者 | Whittingham, J.L., Dodson, E.J., Moody, P.C.E., Dodson, G.G. | | 登録日 | 1995-09-13 | | 公開日 | 1996-01-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol.
Biochemistry, 34, 1995
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2TCI | | X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL | | 分子名称: | THIOCYANATE INSULIN, THIOCYANATE ION, ZINC ION | | 著者 | Whittingham, J.L., Dodson, E.J., Moody, P.C.E., Dodson, G.G. | | 登録日 | 1995-09-13 | | 公開日 | 1996-01-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol.
Biochemistry, 34, 1995
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3MTH | | X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL | | 分子名称: | METHYLPARABEN INSULIN, 4-HYDROXY-BENZOIC ACID METHYL ESTER, ZINC ION, ... | | 著者 | Whittingham, J.L., Dodson, E.J., Moody, P.C.E., Dodson, G.G. | | 登録日 | 1995-09-13 | | 公開日 | 1996-01-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol.
Biochemistry, 34, 1995
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3ROV | | INSULIN'S BIOSYNTHESIS AND ACTIVITY HAVE OPPOSING STRUCTURAL REQUIREMENTS: A NEW FACTOR IN NEONATAL DIABETES MELLITUS | | 分子名称: | Insulin, PHENOL, ZINC ION, ... | | 著者 | Weiss, M.A., Wan, Z.L., Dodson, E.J., Liu, M., Xu, B., Hua, Q.X., Turkenburg, M., Whittingham, J., Nakagawa, S.H., Huang, K., Hu, S.Q., Jia, W.H., Wang, S.H., Brange, J., Whittaker, J., Arvan, P., Katsoyannis, P.G., Dodson, G.G. | | 登録日 | 2011-04-26 | | 公開日 | 2012-05-02 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
To be Published
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1GQM | | THE STRUCTURE OF S100A12 IN A HEXAMERIC FORM AND ITS PROPOSED ROLE IN RECEPTOR SIGNALLING | | 分子名称: | CALGRANULIN C, CALCIUM ION | | 著者 | Moroz, O.V., Antson, A.A., Dodson, E.G., Burrel, H.J., Grist, S.J., Lloyd, R.M., Maitland, N.J., Dodson, G.G., Wilson, K.S., Lukanidin, E., Bronstein, I.B. | | 登録日 | 2001-11-26 | | 公開日 | 2002-02-28 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The Structure of S100A12 in a Hexameric Form and its Proposed Role in Receptor Signalling
Acta Crystallogr.,Sect.D, 58, 2002
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1QAW | | REGULATORY FEATURES OF THE TRP OPERON AND THE CRYSTAL STRUCTURE OF THE TRP RNA-BINDING ATTENUATION PROTEIN FROM BACILLUS STEAROTHERMOPHILUS. | | 分子名称: | TRP RNA-BINDING ATTENUATION PROTEIN, TRYPTOPHAN | | 著者 | Chen, X.-P., Antson, A.A., Yang, M., Baumann, C., Dodson, E.J., Dodson, G.G., Gollnick, P. | | 登録日 | 1999-03-31 | | 公開日 | 1999-04-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Regulatory features of the trp operon and the crystal structure of the trp RNA-binding attenuation protein from Bacillus stearothermophilus.
J.Mol.Biol., 289, 1999
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2Z71 | | STRUCTURE OF TRUNCATED MUTANT CYS1GLY OF PENICILLIN V ACYLASE FROM BACILLUS SPHAERICUS CO-CRYSTALLIZED WITH PENICILLIN V | | 分子名称: | Penicillin acylase, (2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID | | 著者 | Pathak, M.C., Brannigan, J., Dodson, G.G., Suresh, C.G. | | 登録日 | 2007-08-10 | | 公開日 | 2008-08-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Studies on the catalysis and post translational processing of penicillin V acylase
To be published
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3P2X | | INSULIN FIBRILLATION IS THE JANUS FACE OF INDUCED FIT. A CHIARAL CLAMP STABILIZES THE NATIVE STATE AT THE EXPENSE OF ACTIVITY | | 分子名称: | Insulin, ZINC ION, CHLORIDE ION, ... | | 著者 | Hua, Q.X., Wan, Z.L., Huang, K., Hu, S.Q., Phillip, N.F., Jia, W.H., Whittingham, J., Dodson, G.G., Katsoyannis, P.G., Weiss, M.A. | | 登録日 | 2010-10-04 | | 公開日 | 2011-11-23 | | 最終更新日 | 2014-10-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity
To be Published
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3P33 | | INSULIN FIBRILLATION IS THE JANUS FACE OF INDUCED FIT. A CHIRAL CLAMP STABILIZES THE NATIVE STATE AT THE EXPENSE OF ACTIVITY | | 分子名称: | Insulin, PHENOL, ZINC ION, ... | | 著者 | Hua, Q.X., Wan, Z.L., Huang, K., Hu, S.Q., Phillip, N.F., Jia, W.H., Whittingham, J., Dodson, G.G., Katsoyannis, P.G., Weiss, M.A. | | 登録日 | 2010-10-04 | | 公開日 | 2011-11-23 | | 最終更新日 | 2014-10-15 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity
To be Published
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6INS | | X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE | | 分子名称: | INSULIN, ZINC ION | | 著者 | Derewenda, U., Derewenda, Z., Dodson, E.J., Dodson, G.G., Bing, X., Markussen, J. | | 登録日 | 1992-11-25 | | 公開日 | 1994-01-31 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue.
J.Mol.Biol., 220, 1991
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1AX4 | | TRYPTOPHANASE FROM PROTEUS VULGARIS | | 分子名称: | TRYPTOPHANASE, POTASSIUM ION | | 著者 | Isupov, M.N., Antson, A.A., Dodson, E.J., Dodson, G.G., Dementieva, I.S., Zakomirdina, L.N., Wilson, K.S., Dauter, Z., Lebedev, A.A., Harutyunyan, E.H. | | 登録日 | 1997-10-28 | | 公開日 | 1998-01-28 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of tryptophanase.
J.Mol.Biol., 276, 1998
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1IZA | |
1IZB | |
1GKF | | CRYSTAL STRUCTURES OF PENICILLIN ACYLASE ENZYME-SUBSTRATE COMPLEXES: STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM | | 分子名称: | PENICILLIN G ACYLASE ALPHA SUBUNIT, PENICILLIN G ACYLASE BETA SUBUNIT, 1,2-ETHANEDIOL, ... | | 著者 | McVey, C.E., Walsh, M.A., Dodson, G.G., Wilson, K.S., Brannigan, J.A. | | 登録日 | 2001-08-13 | | 公開日 | 2002-01-04 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Crystal Structures of Penicillin Acylase Enzyme- Substrate Complexes: Structural Insights Into the Catalytic Mechanism
J.Mol.Biol., 313, 2001
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1GM7 | | CRYSTAL STRUCTURES OF PENICILLIN ACYLASE ENZYME-SUBSTRATE COMPLEXES: STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM | | 分子名称: | PENICILLIN G ACYLASE ALPHA SUBUNIT, PENICILLIN G ACYLASE BETA SUBUNIT, 1,2-ETHANEDIOL, ... | | 著者 | McVey, C.E., Walsh, M.A., Dodson, G.G., Wilson, K.S., Brannigan, J.A. | | 登録日 | 2001-09-11 | | 公開日 | 2001-11-28 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal Structures of Penicillin Acylase Enzyme- Substrate Complexes: Structural Insights Into the Catalytic Mechanism
J.Mol.Biol., 313, 2001
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1GM8 | | CRYSTAL STRUCTURES OF PENICILLIN ACYLASE ENZYME-SUBSTRATE COMPLEXES: STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM | | 分子名称: | PENICILLIN G ACYLASE ALPHA SUBUNIT, PENICILLIN G ACYLASE BETA SUBUNIT, CALCIUM ION, ... | | 著者 | McVey, C.E., Walsh, M.A., Dodson, G.G., Wilson, K.S., Brannigan, J.A. | | 登録日 | 2001-09-11 | | 公開日 | 2001-11-28 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structures of Penicillin Acylase Enzyme- Substrate Complexes: Structural Insights Into the Catalytic Mechanism
J.Mol.Biol., 313, 2001
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1GM9 | | CRYSTAL STRUCTURES OF PENICILLIN ACYLASE ENZYME-SUBSTRATE COMPLEXES: STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM | | 分子名称: | PENICILLIN G ACYLASE ALPHA SUBUNIT, PENICILLIN G ACYLASE BETA SUBUNIT, 1,2-ETHANEDIOL, ... | | 著者 | McVey, C.E., Walsh, M.A., Dodson, G.G., Wilson, K.S., Brannigan, J.A. | | 登録日 | 2001-09-12 | | 公開日 | 2001-11-28 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structures of Penicillin Acylase Enzyme- Substrate Complexes: Structural Insights Into the Catalytic Mechanism
J.Mol.Biol., 313, 2001
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1PMB | | THE DETERMINATION OF THE CRYSTAL STRUCTURE OF RECOMBINANT PIG MYOGLOBIN BY MOLECULAR REPLACEMENT AND ITS REFINEMENT | | 分子名称: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Smerdon, S.J., Oldfield, T.J., Dodson, E.J., Dodson, G.G., Hubbard, R.E., Wilkinson, A.J. | | 登録日 | 1989-11-27 | | 公開日 | 1990-01-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Determination of the crystal structure of recombinant pig myoglobin by molecular replacement and its refinement.
Acta Crystallogr.,Sect.B, 46, 1990
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1GZR | | HUMAN INSULIN-LIKE GROWTH FACTOR; ESRF DATA | | 分子名称: | INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE | | 著者 | Brzozowski, A.M., Dodson, E.J., Dodson, G.G., Murshudov, G., Verma, C., Turkenburg, J.P., De Bree, F.M., Dauter, Z. | | 登録日 | 2002-05-28 | | 公開日 | 2002-07-25 | | 最終更新日 | 2019-05-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
Biochemistry, 41, 2002
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