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8BF0
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BU of 8bf0 by Molmil
Structure of a Fab portion from TKH2
Descriptor: Anti-dectin-1 15E2 light chain, Anti-lox-1 15C4 heavy chain, CITRIC ACID, ...
Authors:Diskin, R, Borenstein-Katz, A.
Deposit date:2022-10-23
Release date:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of a Fab portion from TKH2
To Be Published
2NPQ
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BU of 2npq by Molmil
A Novel Lipid Binding Site in the p38 alpha MAP Kinase
Descriptor: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
Authors:Diskin, R, Engelberg, D, Livnah, O.
Deposit date:2006-10-29
Release date:2007-10-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A novel lipid binding site formed by the MAP kinase insert in p38 alpha.
J.Mol.Biol., 375, 2008
6QCU
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BU of 6qcu by Molmil
Crystal structure of a Fab portion of the anti EBOV 3T0331 antibody
Descriptor: Heavy chain, Light chain, SULFATE ION
Authors:Diskin, R, Cohen-Dvashi, H.
Deposit date:2018-12-31
Release date:2019-10-02
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:rVSV-ZEBOV induces a polyclonal and convergent B cell response with potent Ebola virus-neutralizing antibodies
Nat.Med. (N.Y.), 2019
6QD8
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BU of 6qd8 by Molmil
EM structure of a EBOV-GP bound to 4M0368 neutralizing antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, Envelope glycoprotein,Virion spike glycoprotein,EBOV-GP1, ...
Authors:Diskin, R, Cohen-Dvashi, H.
Deposit date:2019-01-01
Release date:2019-10-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:rVSV-ZEBOV induces a polyclonal and convergent B cell response with potent Ebola virus-neutralizing antibodies
Nat.Med. (N.Y.), 2019
3U7Y
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BU of 3u7y by Molmil
Structure of NIH45-46 Fab in complex with gp120 of 93TH057 HIV
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CITRATE ANION, ...
Authors:Diskin, R, Bjorkman, P.J.
Deposit date:2011-10-14
Release date:2011-11-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4478 Å)
Cite:Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design.
Science, 334, 2011
3U7W
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BU of 3u7w by Molmil
Crystal structure of NIH45-46 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Heavy chain, ...
Authors:Diskin, R, Bjorkman, P.J.
Deposit date:2011-10-14
Release date:2011-11-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design.
Science, 334, 2011
2FSM
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BU of 2fsm by Molmil
mitogen activated protein kinase p38alpha (D176A+F327S) activating mutant form-B
Descriptor: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
Authors:Diskin, R, Livnah, O.
Deposit date:2006-01-23
Release date:2006-12-05
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation
J.Mol.Biol., 365, 2007
2FST
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BU of 2fst by Molmil
mitogen activated protein kinase p38alpha (D176A+F327L) activating mutant
Descriptor: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
Authors:Diskin, R, Livnah, O.
Deposit date:2006-01-23
Release date:2006-12-05
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation
J.Mol.Biol., 365, 2007
2FSO
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BU of 2fso by Molmil
mitogen activated protein kinase p38alpha (D176A) activating mutant
Descriptor: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
Authors:Diskin, R, Livnah, O.
Deposit date:2006-01-23
Release date:2006-12-05
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation
J.Mol.Biol., 365, 2007
2FSL
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BU of 2fsl by Molmil
mitogen activated protein kinase p38alpha (D176A+F327S) activating mutant form-A
Descriptor: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
Authors:Diskin, R, Livnah, O.
Deposit date:2006-01-23
Release date:2006-12-05
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation
J.Mol.Biol., 365, 2007
3LMJ
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BU of 3lmj by Molmil
Structure of human anti HIV 21c Fab
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Heavy chain of anti HIV Fab from human 21c antibody, Light chain of anti HIV Fab from human 21c antibody
Authors:Diskin, R, Marcovecchio, P.M, Bjorkman, P.J.
Deposit date:2010-01-30
Release date:2010-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity.
Nat.Struct.Mol.Biol., 17, 2010
3LQA
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BU of 3lqa by Molmil
Crystal structure of clade C gp120 in complex with sCD4 and 21c Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, Heavy chain of anti HIV Fab from human 21c antibody, ...
Authors:Diskin, R, Marcovecchio, P.M, Bjorkman, P.J.
Deposit date:2010-02-08
Release date:2010-04-07
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity.
Nat.Struct.Mol.Biol., 17, 2010
4JKP
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BU of 4jkp by Molmil
Restricting HIV-1 Pathways for Escape using Rationally-Designed Anti-HIV-1 Antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody 45-46M2, Light chain of antibody 45-46M2, ...
Authors:Diskin, R, Bjorkman, P.J.
Deposit date:2013-03-11
Release date:2013-05-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies.
J.Exp.Med., 210, 2013
7ZVJ
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BU of 7zvj by Molmil
Homodimeric structure of LARGE1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Diskin, R, Katz, M.
Deposit date:2022-05-16
Release date:2022-11-30
Last modified:2022-12-28
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural basis for matriglycan synthesis by the LARGE1 dual glycosyltransferase.
Plos One, 17, 2022
7PVD
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BU of 7pvd by Molmil
Structure of the membrane soluble spike complex from the Lassa virus in a C1-symmetric map focused on the ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G2, ...
Authors:Diskin, R, Katz, M.
Deposit date:2021-10-02
Release date:2021-12-29
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure and receptor recognition by the Lassa virus spike complex.
Nature, 603, 2022
7PUY
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BU of 7puy by Molmil
Structure of the membrane soluble spike complex from the Lassa virus in a C3-symmetric map
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G2, ...
Authors:Diskin, R, Katz, M.
Deposit date:2021-10-01
Release date:2021-12-29
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure and receptor recognition by the Lassa virus spike complex.
Nature, 603, 2022
6QD7
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BU of 6qd7 by Molmil
EM structure of a EBOV-GP bound to 3T0331 neutralizing antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, Envelope glycoprotein,Virion spike glycoprotein,EBOV-GP1, ...
Authors:Diskin, R, Cohen-Dvashi, H.
Deposit date:2019-01-01
Release date:2019-10-02
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV.
Nat. Med., 25, 2019
6XTG
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BU of 6xtg by Molmil
Ab 1116NS19.9 bound to CA19-9
Descriptor: Heavy chain, Light chain, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Diskin, R, Borenstein-Katz, A.
Deposit date:2020-01-16
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies.
J.Mol.Biol., 433, 2021
6XUN
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BU of 6xun by Molmil
Ab 5b1 bound to CA19-9
Descriptor: GLYCEROL, Heavy chain, Light chain, ...
Authors:Diskin, R, Borenstein-Katz, A.
Deposit date:2020-01-20
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies.
J.Mol.Biol., 433, 2021
6XUK
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BU of 6xuk by Molmil
AbLIFT design 15 of Ab 1116NS19.9
Descriptor: GLYCEROL, Heavy chain, Light chain, ...
Authors:Diskin, R, Borenstein-Katz, A.
Deposit date:2020-01-20
Release date:2021-02-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies.
J.Mol.Biol., 433, 2021
6XUD
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BU of 6xud by Molmil
Apo Ab 1116NS19.9
Descriptor: Heavy chain, Light chain
Authors:Diskin, R, Borenstein-Katz, A.
Deposit date:2020-01-19
Release date:2021-01-27
Last modified:2021-09-29
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies.
J.Mol.Biol., 433, 2021
6XUL
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BU of 6xul by Molmil
Apo Ab 5b1
Descriptor: Heavy chain, Light chain
Authors:Diskin, R, Borenstein-Katz, A.
Deposit date:2020-01-20
Release date:2021-02-03
Last modified:2023-03-08
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies.
J.Mol.Biol., 433, 2021
6S9J
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BU of 6s9j by Molmil
Crystal structure of TfR1 mimicry in complex with GP1 from MACV
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pre-glycoprotein polyprotein GP complex, ...
Authors:Diskin, R, Cohen-Dvashi, H.
Deposit date:2019-07-15
Release date:2020-01-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.698 Å)
Cite:Rational design of universal immunotherapy for TfR1-tropic arenaviruses.
Nat Commun, 11, 2020
3RPI
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BU of 3rpi by Molmil
Crystal Structure of Fab from 3BNC60, Highly Potent anti-HIV Antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain from highly potent anti-HIV neutralizing antibody, Light chain from highly potent anti-HIV neutralizing antibody
Authors:Diskin, R, Bjorkman, P.J.
Deposit date:2011-04-26
Release date:2011-07-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.648 Å)
Cite:Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.
Science, 333, 2011
6S8J
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BU of 6s8j by Molmil
Structure of ZEBOV GP in complex with 5T0180 antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope Glycoprotein 1, Envelope glycoprotein, ...
Authors:Diskin, R, Cohen-Dvashi, H.
Deposit date:2019-07-10
Release date:2020-02-12
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Structural Basis for a Convergent Immune Response against Ebola Virus.
Cell Host Microbe, 27, 2020

 

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